scholarly journals Clinical application of cryolipolysis in Asian patients for subcutaneous fat reduction and body contouring

2020 ◽  
Vol 47 (2) ◽  
pp. 200-200
Author(s):  
Chang Hyun Oh ◽  
Jeong Su Shim ◽  
Kwang Il Bae ◽  
Jae Hoon Chang
Keyword(s):  
Clinical Application ◽  
Subcutaneous Fat ◽  
Body Contouring ◽  
Asian Patients ◽  
Fat Reduction

scholarly journals Clinical application of cryolipolysis in Asian patients for subcutaneous fat reduction and body contouring

2020 ◽  
Vol 47 (1) ◽  
pp. 62-69 ◽  
Author(s):  
Chang Hyun Oh ◽  
Jeong Su Shim ◽  
Kwang Il Bae ◽  
Jae Hoon Chang
Keyword(s):  
Clinical Application ◽  
Subcutaneous Fat ◽  
Body Contouring ◽  
Asian Patients ◽  
Fat Reduction

scholarly journals Utilisation of Cryolipolysis among Asians: A Review on Efficacy and Safety

2019 ◽  
Vol 7 (9) ◽  
pp. 1548-1554 ◽  
Author(s):  
Imam Budi Putra ◽  
Nelva Karmila Jusuf ◽  
Nani Kumala Dewi
Keyword(s):  
Reduction Method ◽  
Subcutaneous Fat ◽  
Body Contouring ◽  
Asian Population ◽  
Caucasian Population ◽  
Efficacy And Safety ◽  
Limited Data ◽  
Non Invasive ◽  
Asian Patients ◽  
Fat Reduction

Cryolipolysis is a non-invasive fat reduction method that is capable of reducing subcutaneous fat significantly without damaging surrounding tissues, by applying cold temperature to induce adipocyte apoptosis. Most of the clinical studies in cryolipolysis were conducted in the Caucasian population, and only a few numbers in Asian, who has darker skin with Fitzpatrick skin type III to V. Higher rate of pigmentary changes were reported with the use of cryotherapy in darker skin. Therefore, this report is aimed to provide a comprehensive review regarding utilisation, efficacy and safety profiles of cryolipolysis among Asians. Currently, there are only four clinical trials conducted exclusively in an Asian population. Two studies were conducted in Korea, whereas others in China and Thailand. Cryolipolysis was performed in the abdomen, arm, inner thighs, and submental regions. The reported side effects were mild and transient, including erythema, hematoma, numbness, and pain. There were no pigmentary changes reported. Although only limited data available, those studies have proved that cryolipolysis utilisation among Asians or darker skin types provides the same efficacy and safety profiles as in Caucasians. Therefore, cryolipolysis might be proposed as the first treatment choice for Asian patients who opted to do body contouring.

scholarly journals The Effects of Low-Intensity Ultrasound on Fat Reduction of Rat Model

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Bill Zhou ◽  
Benny Yuk Kin Leung ◽  
Lei Sun
Keyword(s):  
Body Fat ◽  
Lipid Level ◽  
Subcutaneous Fat ◽  
Body Contouring ◽  
Plasma Lipid ◽  
High Intensity Focused Ultrasound ◽  
Plasma Lipid Level ◽  
Low Intensity ◽  
Fat Reduction ◽  
Low Intensity Ultrasound

Nonfocused low-intensity ultrasound is generally believed to be less efficacious than High-Intensity Focused Ultrasound (HIFU) at body fat reduction; nevertheless, this technology has already been widely used clinically for body contouring purposes. This study aimed to evaluate the efficacy and safety of this new technology by applying 1 MHz nonfocused ultrasound at 3 W/cm2to the outer-thigh region of rat models. Ultrasonography measurement demonstrated an average reduction of 0.5 mm of subcutaneous fat thickness that persisted for at least three days after treatment. Biochemical analysis quantified a significant increase in lipid levels, specifically triglyceride, high-density lipoprotein, and total cholesterol. These two findings of subcutaneous fat reduction and plasma lipid increase showed a positive correlation. No evidence of adverse events or complications was observed after the treatment. This study validated nonfocused low-intensity ultrasound as an effective and safe method for body fat reduction, especially with repetitive treatment. However, the concurrent increase in plasma lipid level will require further investigation to determine this technology’s long-term impact, if any, on health.

scholarly journals Effectiveness and Safety of Contrast Cryolipolysis for Subcutaneous-Fat Reduction

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Marília Bueno Savacini ◽  
Débora Tazinaffo Bueno ◽  
Ana Carolina Souza Molina ◽  
Ana Caroline Almeida Lopes ◽  
Caroline Nogueira Silva ◽  
...  
Keyword(s):  
Laboratory Testing ◽  
Subcutaneous Fat ◽  
Body Contouring ◽  
Noninvasive Treatment ◽  
Fat Reduction ◽  
Laboratory Results ◽  
Safety Assessments ◽  
Level Of Significance ◽  
Skinfold Caliper

Cryolipolysis is the noninvasive treatment of localized fat through cold-induced panniculitis. The purpose of the present study was to evaluate the safety and efficacy of contrast cryolipolysis for subcutaneous-fat reduction. Contrast cryolipolysis mixes the principles of conventional cryolipolysis and periods of heating in accordance with the contrast lipocryolysis process. Twenty-one subjects aged 34 ± 9 years were treated with contrast cryolipolysis in the regions of abdomen and flanks through the Polarys® device. Anthropometry, standardized photographs, measurements with a skinfold caliper, and diagnostic ultrasounds were performed at the baseline and during follow-ups at 30, 60, and 90 days after the treatment. The safety assessments included laboratory testing and monitoring of the adverse events. The level of significance for all tests was set at P < 0.05. No significant differences in weight and body mass index were found. The waist measurements at the baseline and 30-day follow-up had significant differences, as did the measurements at the 30-day and 60-day follow-ups. The skinfold and ultrasound measurements were significantly reduced in the treated areas in all the time points compared to the baseline. The laboratory results showed no significant changes from baseline. Temporary adverse effects were resolved spontaneously. This study confirmed that contrast cryolipolysis is safe and effective in reducing the fat layer and improving body contouring.

scholarly journals Age-related skin changes

2012 ◽  
Vol 65 (5-6) ◽  
pp. 191-195 ◽  
Author(s):  
Aleksandra Levakov ◽  
Nada Vuckovic ◽  
Matilda Djolai ◽  
Mihaela Mocko-Kacanski ◽  
Snezana Bozanic
Keyword(s):  
Inflammatory Infiltrate ◽  
Subcutaneous Fat ◽  
The Sun ◽  
Intercellular Substance ◽  
Dermoepidermal Junction ◽  
Skin Changes ◽  
Age Related ◽  
Fat Reduction ◽  
Males And Females ◽  
Skin Samples

Age-related skin changes can be induced by chronological ageing, manifested in subcutaneous fat reduction, and photo-ageing eliciting increased elastotic substance in the upper dermis, destruction of its fibrilar structure, augmented intercellular substance and moderate inflammatory infiltrate. Forty-five biopsy skin samples of the sun-exposed and sun-protected skin were analyzed. The patients were both males and females, aged from 17 to 81 years. The thickness of the epidermal layers and the number of cellular living layers is greater in younger skin. The amount of keratohyaline granules is enlarged in older skin. Dermoepidermal junction is flattened and the presence of elastotic material in the dermis is pronounced with age. The amount of inflammatory infiltrate is increased, the fibrous trabeculae are thickened in older skin and the atrophy of the hypodermis is observed. Chronological ageing alters the fibroblasts metabolism by reducing their life span, capacity to divide and produce collagen. During ageing, the enlargement of collagen fibrils diminishes the skin elasticity.

Evaluation of a novel device, high-intensity focused ultrasound with a contact cooling for subcutaneous fat reduction

2016 ◽  
Vol 48 (9) ◽  
pp. 878-886 ◽  
Author(s):  
Heun Joo Lee ◽  
Mi-Hye Lee ◽  
Su Gun Lee ◽  
Un-Cheol Yeo ◽  
Sung Eun Chang
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
Subcutaneous Fat ◽  
High Intensity Focused Ultrasound ◽  
Novel Device ◽  
Fat Reduction

scholarly journals lipodissolve for subcutaneous fat reduction and skin retraction

2005 ◽  
Vol 25 (5) ◽  
pp. 530-543 ◽  
Author(s):  
D DUNCAN ◽  
F HASENGSCHWANDTNER
Keyword(s):  
Subcutaneous Fat ◽  
Fat Reduction ◽  
Skin Retraction

scholarly journals Efficacy and Safety of Combined Extracts of Cornus officinalis and Ribes fasciculatum for Body Fat Reduction in Overweight Women

2020 ◽  
Vol 9 (11) ◽  
pp. 3629
Author(s):  
Eunkuk Park ◽  
Chang Gun Lee ◽  
Jeonghyun Kim ◽  
Jae-Heon Kang ◽  
Young Gyu Cho ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Body Fat ◽  
Safety Assessment ◽  
Subcutaneous Fat ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
Waist To Hip Ratio ◽  
Overweight Women ◽  
Cornus Officinalis ◽  
Fat Reduction

Obesity is a medical condition that presents excessive fat accumulation with high risk of serious chronic diseases. The aim of this clinical trial is to investigate the anti-obesity effects of Cornus officinalis (CO) and Ribes fasciculatum (RF) on body fat reduction in Korean overweight women. A total of 147 overweight female participants enrolled in double-blinded clinical trial for 12 weeks and 76 participants completed the clinical study. Participants were treated with four CO and RF mixture (COEC; 400 mg per tablet) or four placebo tablets once a day. Obesity associated parameters (body weight, body mass index (BMI), waist circumference, waist-to-hip ratio, body fat percentage and body fat mass) and safety assessment were analyzed. After 12 weeks of COEC treatment, primary outcomes such as body fat percentage (0.76% vs. 0.01%; p = 0.022) and mass (1.1 kg vs. 0.5 kg; p = 0.049) were significantly decreased. In addition, the results were statistically significant between the COEC and placebo groups, strongly indicated that COEC had anti-obesity effects on overweight women. Secondary outcomes—including body weight, waist and hip circumference, waist-to-hip ratio, body mass index and computed tomography measurement of visceral fat area, subcutaneous fat area, total abdominal fat area and visceral-to-subcutaneous fat ratio—were reduced in COEC-treated group, but no statistical differences were found between the COEC and placebo groups. The safety assessment did not differ between the two groups. These results suggest that treatment of COEC extract reduces body fat percentage and mass in Korean overweight women, indicating it as a protective functional agent for obesity.

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