scholarly journals Efficacy and Safety of Combined Extracts of Cornus officinalis and Ribes fasciculatum for Body Fat Reduction in Overweight Women

2020 ◽  
Vol 9 (11) ◽  
pp. 3629
Author(s):  
Eunkuk Park ◽  
Chang Gun Lee ◽  
Jeonghyun Kim ◽  
Jae-Heon Kang ◽  
Young Gyu Cho ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Body Fat ◽  
Safety Assessment ◽  
Subcutaneous Fat ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
Waist To Hip Ratio ◽  
Overweight Women ◽  
Cornus Officinalis ◽  
Fat Reduction

Obesity is a medical condition that presents excessive fat accumulation with high risk of serious chronic diseases. The aim of this clinical trial is to investigate the anti-obesity effects of Cornus officinalis (CO) and Ribes fasciculatum (RF) on body fat reduction in Korean overweight women. A total of 147 overweight female participants enrolled in double-blinded clinical trial for 12 weeks and 76 participants completed the clinical study. Participants were treated with four CO and RF mixture (COEC; 400 mg per tablet) or four placebo tablets once a day. Obesity associated parameters (body weight, body mass index (BMI), waist circumference, waist-to-hip ratio, body fat percentage and body fat mass) and safety assessment were analyzed. After 12 weeks of COEC treatment, primary outcomes such as body fat percentage (0.76% vs. 0.01%; p = 0.022) and mass (1.1 kg vs. 0.5 kg; p = 0.049) were significantly decreased. In addition, the results were statistically significant between the COEC and placebo groups, strongly indicated that COEC had anti-obesity effects on overweight women. Secondary outcomes—including body weight, waist and hip circumference, waist-to-hip ratio, body mass index and computed tomography measurement of visceral fat area, subcutaneous fat area, total abdominal fat area and visceral-to-subcutaneous fat ratio—were reduced in COEC-treated group, but no statistical differences were found between the COEC and placebo groups. The safety assessment did not differ between the two groups. These results suggest that treatment of COEC extract reduces body fat percentage and mass in Korean overweight women, indicating it as a protective functional agent for obesity.

scholarly journals Antiobesity Effect of Caraway Extract on Overweight and Obese Women: A Randomized, Triple-Blind, Placebo-Controlled Clinical Trial

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Mahnaz Kazemipoor ◽  
Che Wan Jasimah Bt wan Mohamed Radzi ◽  
Majid Hajifaraji ◽  
Batoul Sadat Haerian ◽  
Mohammad Hossein Mosaddegh ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Body Fat ◽  
Urine Specific Gravity ◽  
Controlled Clinical Trial ◽  
Body Fat Percentage ◽  
Obese Women ◽  
Fat Percentage ◽  
Anthropometric Indices ◽  
Physically Active ◽  
Waist To Hip Ratio

Caraway (Carum carviL.), a potent medicinal plant, is traditionally used for treating obesity. This study investigates the weight-lowering effects of caraway extract (CE) on physically active, overweight and obese women through a randomized, triple-blind, placebo-controlled clinical trial. Seventy overweight and obese, healthy, aerobic-trained, adult females were randomly assigned to two groups (n=35per group). Participants received either 30 mL/day of CE or placebo without changing their diet or physical activity. Subjects were examined at baseline and after 90 days for changes in body composition, anthropometric indices, and clinical and paraclinical variables. The treatment group, compared with placebo, showed a significant reduction of weight, body mass index, body fat percentage, and waist-to-hip ratio. No changes were observed in lipid profile, urine-specific gravity, and blood pressure of subjects. The results suggest that a dietary CE with no restriction in food intake, when combined with exercise, is of value in the management of obesity in women wishing to lower their weight, BMI, body fat percentage, and body size, with no clinical side effects. In conclusion, results of this study suggest a possible phytotherapeutic approach for caraway extract in the management of obesity. This trial is registered withNCT01833377.

scholarly journals Body Fat Percentage, Waist Circumference and Body Mass Index are Correlated with Nitric Oxide Levels in Young Adults with Central Obesity

2021 ◽  
Vol 5 (1) ◽  
pp. 1
Author(s):  
Feriyandi Nauli ◽  
Nurhasanah Nurhasanah ◽  
Endang Mahati ◽  
Udin Bahrudin
Keyword(s):  
Nitric Oxide ◽  
Body Mass Index ◽  
Young Adults ◽  
Waist Circumference ◽  
Body Mass ◽  
Body Fat ◽  
Central Obesity ◽  
Subcutaneous Fat ◽  
Body Fat Percentage ◽  
Fat Percentage

Background: Central obesity stands for the corner-stone of cardio-metabolic health, while nitric oxide (NO) is a major regulator of cardiovascular function. To day, the correlation between serum NO metabolites nitrate/nitrite and the obesity components in young adults remains elusive. Thus, this current study was conducted to know the correlation between serum NO metabolites levels and body fat percentage, waist circumference (WC) as well as body mass index (BMI) in young adults with central obesity.Materials and Methods: A cross-sectional study was conducted in Riau, Indonesia, involving 79 young adults aged 18-25 years, composing of 39 and 40 subjects with and without central obesity, respectively. Anthropometric measurements were performed to assess WC and BMI. Body fat percentage was measured using bioelectrical impedance analysis and serum NO metabolites levels were assessed using Griess methods.Results: Levels of serum NO metabolites were significant higher in the subjects with central obesity (168.41±12.64 μmol/L) than that of normal subjects (70.57±44.99 μmol/L, p<0.001), but the levels were no significant different between male and female subjects. Serum NO metabolites levels were strongly correlated with total body fat (r=0.618, p<0.001), visceral fat (r=0.733, p<0.001), subcutaneous fat (r=0.547, p<0.001), WC (r=0.717, p<0.001) and BMI (r=0.788, p<0.001).Conclusions: For young adults in Riau, Indonesia, levels of serum NO metabolites are higher in the central obesity group than that of the normal. In this population, body fat percentage, waist circumference and body mass index are correlated with serum nitric oxide metabolites levels.Keywords: nitric oxide, body fat percentage, young adults, central obesity

Ultrasound Measurements of Subcutaneous Fat Thickness Are Robust Against Hydration Changes

2020 ◽  
pp. 1-6
Author(s):  
Dale R. Wagner ◽  
James D. Cotter
Keyword(s):  
Body Composition ◽  
Body Fat ◽  
Subcutaneous Fat ◽  
Hydration Status ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
Ultrasound Measurements ◽  
Subcutaneous Fat Thickness ◽  
Fat Thickness ◽  
The Impact

Ultrasound is an appealing tool to assess body composition, combining the portability of a field method with the accuracy of a laboratory method. However, unlike other body composition methods, the effect of hydration status on validity is unknown. This study evaluated the impact of acute hydration changes on ultrasound measurements of subcutaneous fat thickness and estimates of body fat percentage. In a crossover design, 11 adults (27.1 ± 10.5 years) completed dehydration and hyperhydration trials to alter body mass by approximately ±2%. Dehydration was achieved via humid heat (40 °C, 60% relative humidity) with exercise, whereas hyperhydration was via ingestion of lightly salted water. Ultrasound measurements were taken at 11 body sites before and after each treatment. Participants lost 1.56 ± 0.58 kg (−2.0 ± 0.6%) during the dehydration trial and gained 0.90 ± 0.21 kg (1.2 ± 0.2%) during the hyperhydration trial even after urination. The sum of fat thicknesses as measured by ultrasound differed by <0.90 mm across trials (p = .588), and ultrasound estimates of body fat percentage differed by <0.5% body fat. Ultrasound measures of subcutaneous adipose tissue were unaffected by acute changes in hydration status by extents beyond which are rare and overtly self-correcting, suggesting that this method provides reliable and robust body composition results even when subjects are not euhydrated.

scholarly journals Association of Sugar-Sweetened Beverage Frequency with Adiposity: Evidence from the “Children of 1997” Birth Cohort

Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 1015
Author(s):  
Ting Zhang ◽  
Shiu Lun Au Yeung ◽  
Man Ki Kwok ◽  
Lai Ling Hui ◽  
Gabriel Matthew Leung ◽  
...  
Keyword(s):  
Waist Circumference ◽  
Birth Cohort ◽  
Body Fat ◽  
Body Fat Percentage ◽  
Z Score ◽  
Fat Percentage ◽  
Sugar Sweetened Beverage ◽  
Waist To Hip Ratio ◽  
Sweetened Beverage ◽  
Consumption Frequency

Background: Observationally, sugar-sweetened beverage (SSB) consumption is associated with adiposity in Western children but could be confounded. We examined the association of SSB frequency with adiposity in the non-Western setting of Hong Kong. Methods: We examined the associations of SSB consumption frequency at 11 and 13 years assessed by using a food frequency questionnaire with subsequent body mass index (BMI) z-score and overweight/obesity up to 18 years using generalized estimating equations, and with waist circumference, waist-to-hip ratio, and body fat percentage at 16–19 years using linear regression in a population-representative Chinese birth cohort “Children of 1997” (n = 3628). Results: At 11 and 13 years, 6.8% and 8.2% of children respectively consumed SSB daily. Neither SSB frequency at 11 nor at 13 years was associated with subsequent BMI z-score or overweight/obesity up to 18 years, or with waist circumference, waist-to-hip ratio, or body fat percentage at 16–19 years adjusted for age, sex, socioeconomic position, health status, physical activity and other food consumption, although bias to the null from under-reporting cannot be eliminated. Conclusion: Although we cannot definitively exclude a small association of SSB frequency with adiposity, lack of association of SSB frequency with adiposity in a non-Western setting with low SSB consumption suggests that the role of SSB in adiposity appears to be minor.

Body fat percentage, body mass index and waist-to-hip ratio as predictors of mortality and cardiovascular disease

Heart ◽  
2014 ◽  
Vol 100 (20) ◽  
pp. 1613-1619 ◽  
Author(s):  
Phyo Kyaw Myint ◽  
Chun Shing Kwok ◽  
Robert N Luben ◽  
Nicholas J Wareham ◽  
Kay-Tee Khaw
Keyword(s):  
Cardiovascular Disease ◽  
Body Mass Index ◽  
Body Mass ◽  
Body Fat ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
Waist To Hip Ratio ◽  
Predictors Of Mortality

Effects of weight loss using supplementation with Lactobacillus strains on body fat and medium-chain acylcarnitines in overweight individuals

2017 ◽  
Vol 8 (1) ◽  
pp. 250-261 ◽  
Author(s):  
Minkyung Kim ◽  
Minjoo Kim ◽  
Miso Kang ◽  
Hye Jin Yoo ◽  
Min Sun Kim ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Body Fat ◽  
Subcutaneous Fat ◽  
The Body ◽  
Body Fat Percentage ◽  
Body Fat Mass ◽  
Fat Percentage ◽  
Probiotic Supplementation ◽  
Percentage Body Fat

Probiotic supplementation increased the levels of C8:1, C14:1, C10, and C12:1 acylcarnitines, and these increases were correlated with a decrease in the body weight, body fat percentage, body fat mass and L1 subcutaneous fat area.

scholarly journals Network Mendelian randomization study: exploring the causal pathway from insomnia to type 2 diabetes

2022 ◽  
Vol 10 (1) ◽  
pp. e002510
Author(s):  
Wen Xiuyun ◽  
Lin Jiating ◽  
Xie Minjun ◽  
Li Weidong ◽  
Wu Qian ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Body Fat ◽  
Mendelian Randomization ◽  
Body Fat Percentage ◽  
Causal Association ◽  
Fat Percentage ◽  
Waist To Hip Ratio ◽  
Increased Risk ◽  
Causal Pathway

IntroductionInsomnia is a novel pathogen for type 2 diabetes mellitus (T2DM). However, mechanisms linking insomnia and T2DM are poorly understood. In this study, we apply a network Mendelian randomization (MR) framework to determine the causal association between insomnia and T2DM and identify the potential mediators, including overweight (body mass index (BMI), waist-to-hip ratio, and body fat percentage) and glycometabolism (HbA1c, fasting blood glucose, and fasting blood insulin).Research design and methodsWe use the MR framework to detect effect estimates of the insomnia–T2DM, insomnia–mediator, and mediator–T2DM associations. A mediator between insomnia and T2DM is established if MR studies in all 3 steps prove causal associations.ResultsIn the Inverse variance weighted method, the results show that insomnia will increase the T2DM risk (OR 1.142; 95% CI 1.072 to 1.216; p=0.000), without heterogeneity nor horizontal pleiotropy, strongly suggesting that genetically predicted insomnia has a causal association with T2DM. Besides, our MR analysis provides strong evidence that insomnia is causally associated with BMI and body fat percentage. There is also suggestive evidence of an association between insomnia and the waist-to-hip ratio. At the same time, our results indicate that insomnia is not causally associated with glycometabolism. Higher BMI, waist-to-hip ratio, and body fat percentage levels are strongly associated with increased risk of T2DM.ConclusionsGenetically predicted insomnia has a causal association with T2DM. Being overweight (especially BMI and body fat percentage) mediates the causal pathway from insomnia to T2DM.

scholarly journals Asian Indian adolescents from Guadeloupe are fatter than their island counterparts

2009 ◽  
Vol 102 (12) ◽  
pp. 1820-1827 ◽  
Author(s):  
Stéphane Sinnapah ◽  
Sophie Antoine-Jonville ◽  
Olivier Hue
Keyword(s):  
Asian Indian ◽  
Body Fat ◽  
Asian Indians ◽  
Task Force ◽  
Subcutaneous Fat ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
Indian Adolescents

The present study aimed at comparing the anthropometric profile of Asian Indian adolescents from Guadeloupe with that of their island counterparts. A total of 720 voluntary 11- to 17-year-old students participated: 180 Asian Indians and 540 age- and sex-matched students of other origin. Weight and height were measured to calculate the BMI. Waist and hip circumferences and bicipital, tricipital, subscapular and supra-iliac skinfold thicknesses were assessed. The percentage of body fat was estimated by bioelectrical impedance analysis. Obesity was defined from BMI according to the International Obesity Task Force recommendations. Asian Indians were smaller and lighter than their counterparts. They had a higher body fat percentage even after adjustment on BMI but the prevalence of obesity did not differ, with an overall prevalence of 5·69 (95 % CI 5·67, 5·71) %. No principal effects of ethnicity on waist and hip circumferences or the waist:hip ratio were evidenced. The sum of the four skinfold thicknesses was the strongest predictor of body fat percentage, and the adjustment of overall body fat on subcutaneous fat cancelled the effect of ethnicity on this dependent variable. The present study found that Asian Indian adolescents from Guadeloupe had the same tendency toward higher body fat and body fat-for-BMI as previously documented in Asian Indian adults. It raises the hypothesis of a higher cardiovascular risk in this ethnic group from adolescence and questions the validity of using common BMI references for screening obesity in multiethnic communities.

scholarly journals AB0519 PHYSICAL ACTIVITY AND OBESITY IN PATIENTS WITH ANKYLOSING SPONDYLITIS

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1286.2-1286
Author(s):  
R. Dhahri ◽  
S. Miri ◽  
M. Slouma ◽  
B. Louzir ◽  
L. Metoui ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cardiovascular Risk ◽  
Ankylosing Spondylitis ◽  
Waist Circumference ◽  
Body Fat ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
Hip Circumference ◽  
Waist To Hip Ratio ◽  
The Mean

Background:Ankylosing Spondylitis (AS) is associated with an increased cardiovascular risk. Obesity and limited activity in patients with AS may contribute to this cardiovascular risk.Objectives:We aimed to evaluate physical Activity and obesity in patients with AS.Methods:We conducted a cross-sectional observational study of 40 patients with AS, over a period of 3 months. We evaluated the level of physical activity using the IPAQ (International Physical Activity Questionnaire). We also measured body mass index (BMI), body fat percentage, waist circumference, hip circumference and their ratio in all patients.Results:The mean age of our population was 44±10 years. A male predominance was noted with a sex ratio =11.1. The mean ASDAS-CRP and BASDAI levels were 2.1±0.95 and 2.25±1.33. The mean of IPAQ was 3900 MET minutes per week, with a median of 3069 and extremes of 339 and 11000. 45.5% of patients had moderate physical activity and 20% had low activity.The mean BMI was 26.5 + 4.7 kg/m2. Twenty percent of patients were obese. The mean body fat percentage was 25% with a median of 23.7% and extremes of 8-46%. Forty-five percent of the patients had a high fat mass. The mean waist circumference was 95±13 cm, hip circumference 104±9.5 cm. The mean waist to hip ratio was 0.9±0.07. Thirty-seven percent of patients had a high waist to hip ratio. BMI and body fat percentage were negatively correlated with HDL level; (r=-0.365,p=0.024)and(r=-0.393,p=0.015) respectively.Conclusion:The majority of our patients have moderate or low levels of physical activity. The increase in BMI and fat mass appear to be associated with disturbance of the lipid balance, with low HDL values.Disclosure of Interests:None declared.

scholarly journals The combined effect of green tea and α-glucosyl hesperidin in preventing obesity: a randomized placebo-controlled clinical trial

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ren Yoshitomi ◽  
Mao Yamamoto ◽  
Motofumi Kumazoe ◽  
Yoshinori Fujimura ◽  
Madoka Yonekura ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Weight Gain ◽  
Green Tea ◽  
Body Fat ◽  
Controlled Clinical Trial ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
Reduced Body ◽  
Blood Biochemical ◽  
Double Blinded

AbstractGreen tea, a widely consumed beverage in Asia, contains green tea catechins effective against obesity, especially epigallocatechin-3-O-gallate (EGCG), but must be consumed in an impractically huge amount daily to elicit its biological effect. Meanwhile, citrus polyphenols have various physiological effects that could enhance EGCG functionality. Here we investigated the antiobesity effect of a combination of EGCG and α-glucosyl hesperidin, a citrus polyphenol, at doses that have not been previously reported to exert antiobesity effects by themselves in any clinical trial. In a randomized, placebo-controlled, double-blinded, and parallel-group-designed clinical trial, 60 healthy Japanese males and females aged 30–75 years consumed green tea combined with α-glucosyl hesperidin (GT-gH), which contained 178 mg α-glucosyl hesperidin and 146 mg EGCG, for 12 weeks. Physical, hematological, blood biochemical, and urine examinations showed that GT-gH is safe to use. At week 12, GT-gH prevented weight gain and reduced body mass index (BMI) compared with the placebo. Especially in those aged < 50 years, triglyceride and body fat percentage decreased at week 6, visceral fat level and body fat percentage decreased at week 12; body weight, BMI, and blood LDL/HDL ratio also decreased. In conclusion, taking GT-gH prevents weight gain, and the antiobesity effect of GT-gH was more pronounced in people aged < 50 years.

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