scholarly journals The Effects of Low-Intensity Ultrasound on Fat Reduction of Rat Model

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Bill Zhou ◽  
Benny Yuk Kin Leung ◽  
Lei Sun

Nonfocused low-intensity ultrasound is generally believed to be less efficacious than High-Intensity Focused Ultrasound (HIFU) at body fat reduction; nevertheless, this technology has already been widely used clinically for body contouring purposes. This study aimed to evaluate the efficacy and safety of this new technology by applying 1 MHz nonfocused ultrasound at 3 W/cm2to the outer-thigh region of rat models. Ultrasonography measurement demonstrated an average reduction of 0.5 mm of subcutaneous fat thickness that persisted for at least three days after treatment. Biochemical analysis quantified a significant increase in lipid levels, specifically triglyceride, high-density lipoprotein, and total cholesterol. These two findings of subcutaneous fat reduction and plasma lipid increase showed a positive correlation. No evidence of adverse events or complications was observed after the treatment. This study validated nonfocused low-intensity ultrasound as an effective and safe method for body fat reduction, especially with repetitive treatment. However, the concurrent increase in plasma lipid level will require further investigation to determine this technology’s long-term impact, if any, on health.

2016 ◽  
Vol 48 (9) ◽  
pp. 878-886 ◽  
Author(s):  
Heun Joo Lee ◽  
Mi-Hye Lee ◽  
Su Gun Lee ◽  
Un-Cheol Yeo ◽  
Sung Eun Chang

2020 ◽  
Vol 9 (11) ◽  
pp. 3629
Author(s):  
Eunkuk Park ◽  
Chang Gun Lee ◽  
Jeonghyun Kim ◽  
Jae-Heon Kang ◽  
Young Gyu Cho ◽  
...  

Obesity is a medical condition that presents excessive fat accumulation with high risk of serious chronic diseases. The aim of this clinical trial is to investigate the anti-obesity effects of Cornus officinalis (CO) and Ribes fasciculatum (RF) on body fat reduction in Korean overweight women. A total of 147 overweight female participants enrolled in double-blinded clinical trial for 12 weeks and 76 participants completed the clinical study. Participants were treated with four CO and RF mixture (COEC; 400 mg per tablet) or four placebo tablets once a day. Obesity associated parameters (body weight, body mass index (BMI), waist circumference, waist-to-hip ratio, body fat percentage and body fat mass) and safety assessment were analyzed. After 12 weeks of COEC treatment, primary outcomes such as body fat percentage (0.76% vs. 0.01%; p = 0.022) and mass (1.1 kg vs. 0.5 kg; p = 0.049) were significantly decreased. In addition, the results were statistically significant between the COEC and placebo groups, strongly indicated that COEC had anti-obesity effects on overweight women. Secondary outcomes—including body weight, waist and hip circumference, waist-to-hip ratio, body mass index and computed tomography measurement of visceral fat area, subcutaneous fat area, total abdominal fat area and visceral-to-subcutaneous fat ratio—were reduced in COEC-treated group, but no statistical differences were found between the COEC and placebo groups. The safety assessment did not differ between the two groups. These results suggest that treatment of COEC extract reduces body fat percentage and mass in Korean overweight women, indicating it as a protective functional agent for obesity.


2020 ◽  
Vol 47 (2) ◽  
pp. 200-200
Author(s):  
Chang Hyun Oh ◽  
Jeong Su Shim ◽  
Kwang Il Bae ◽  
Jae Hoon Chang

2020 ◽  
Vol 46 (2) ◽  
pp. 213-219 ◽  
Author(s):  
Ji Yeon Hong ◽  
Eun Jung Ko ◽  
Sun Young Choi ◽  
Tae-Rin Kwon ◽  
Jong Hwan Kim ◽  
...  

1965 ◽  
Vol 29 (10) ◽  
pp. 937-942 ◽  
Author(s):  
KAORU OYAMA ◽  
HARUO UZAWA ◽  
MASAKI MATSUDA ◽  
KUNITARO IMAICH

2011 ◽  
Vol 43 (07) ◽  
pp. 458-463 ◽  
Author(s):  
C-S. Niu ◽  
H-T. Wu ◽  
K-C. Cheng ◽  
K-C. Lin ◽  
C-T. Chen ◽  
...  

PEDIATRICS ◽  
1985 ◽  
Vol 75 (3) ◽  
pp. 541-546
Author(s):  
Yoshiki Takashima ◽  
Tatsuhiko Kodama ◽  
Hisaya lida ◽  
Masahiko Kawamura ◽  
Hiroyuki Aburatani ◽  
...  

The plasma lipoproteins of a 1-year-old Japanese infant were studied because of malnutrition, severe decrease in plasma lipid level, and acanthocytosis. Plasma lipoprotein analysis revealed that low-density lipoproteins were deficient; however, low levels of triglyceride-rich lipoproteins were found in the plasma. On sodium dodecylsulfate (SDS) polyacrylamide gel electro-phoresis, apoprotein B-48 and a faint band corresponding to apoprotein B-100 were detected in the lipoprotein fraction of density < 1.006 g/mL when the infant was 6 months old. Apoprotein B-48 was more clearly detected after 1 year, but the band corresponding to apoprotein B-100 on the sodium dodecylsulfate gel electrophoresis had disappeared. The apoprotein B-48 content of the fraction with density < 1.006 g/mL was about 0.05 to 0.3 mg/dL. The patient's lipoproteins consisted mainly of high-density lipoproteins. These results suggest that the disorder in this patient is caused by apoprotein B-100 deficiency.


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