scholarly journals The role of reflectance confocal microscopy in a case of Bowen’s disease difficult to diagnose

2018 ◽  
pp. 63-65 ◽  
Author(s):  
Isil Karaarslan ◽  
Sibel Tepret ◽  
Seda Yildiz ◽  
Banu Yaman ◽  
Fezal Ozdemir
Keyword(s):  
Confocal Microscopy ◽  
Reflectance Confocal Microscopy ◽  
Bowen’S Disease ◽  
Bowen's Disease

Reflectance confocal microscopy of Pigmented Bowen's disease: misleading dendritic cells

2016 ◽  
Vol 23 (1) ◽  
pp. 126-128 ◽  
Author(s):  
S. Debarbieux ◽  
J. L. Perrot ◽  
E. Cinotti ◽  
B. Labeille ◽  
J. Fontaine ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Confocal Microscopy ◽  
Reflectance Confocal Microscopy ◽  
Bowen’S Disease ◽  
Bowen's Disease

scholarly journals Reflectance Confocal Microscopy of Pigmented Bowen’s Disease: A Case Series of Difficult to Diagnose Lesions

2020 ◽  
Vol 12 (2) ◽  
pp. 98-106
Author(s):  
Sara Mazzilli ◽  
Reyes Gamo-Villegas ◽  
Ana Pampin-Franco ◽  
Jose Luis Lopez Estebaran ◽  
Fernando Pinedo ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Cell Carcinoma ◽  
Histopathological Examination ◽  
Case Series ◽  
The Body ◽  
Reflectance Confocal Microscopy ◽  
Bowen’S Disease ◽  
Seborrheic Keratosis ◽  
Bowen's Disease ◽  
Precise Diagnosis

Pigmented Bowen’s disease is a rare variant of in situ squamous skin cell carcinoma. It mainly affects patients between 60 and 70 years of age. Its clinical features include well-demarcated, pigmented plaque arising in photo-exposed areas of the body. The best-characterized feature of the disease by histological examination is the presence of atypical keratinocytes, hyperpigmentation of the epidermis with trans-epidermal elimination of melanin and dermal melanophages. Precise diagnosis is often difficult, both clinically and dermoscopically, as Bowen’s disease is often mistaken with keratinocyte tumors such as solar lentigines, seborrheic keratosis, Bowenoid papulosis, pigmented basal cell carcinoma, pigmented actinic keratosis; or even melanocytic lesions such as melanocytic nevus, pigmented epithelioid melanocytoma, and melanoma. Precise diagnosis often requires biopsy and histopathological examination of the tissue. Reflectance confocal microscopy is a noninvasive technique to diagnose pigmented skin lesions. To date, not much data are available regarding its use in the diagnosis of pigmented Bowen’s disease. Herein, we report a well-represented case series of pigmented Bowen’s disease imaged using dermoscopy and reflectance confocal microscopy.

Treatment of Extramammary Paget Disease and the Role of Reflectance Confocal Microscopy: A Prospective Study

2021 ◽  
Vol 47 (4) ◽  
pp. 473-479
Author(s):  
Cristian Navarrete-Dechent ◽  
Saud Aleissa ◽  
Miguel Cordova ◽  
Brian P. Hibler ◽  
Andres M. Erlendsson ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Prospective Study ◽  
Reflectance Confocal Microscopy ◽  
Paget Disease ◽  
A Prospective Study

scholarly journals The Differential Diagnosis of Hypopigmented Mycosis Fungoides and Vitiligo With Reflectance Confocal Microscopy: A Preliminary Study

2021 ◽  
Vol 7 ◽  
Author(s):  
Huaxu Liu ◽  
Leilei Wang ◽  
Yan Lin ◽  
Xiaofeng Shan ◽  
Min Gao
Keyword(s):  
Differential Diagnosis ◽  
Confocal Microscopy ◽  
Mycosis Fungoides ◽  
Early Stage ◽  
Reflectance Confocal Microscopy ◽  
Inflammatory Conditions ◽  
Dark Space ◽  
Superficial Dermis ◽  
Melanin Contents

Objective: To investigate the role of reflectance confocal microscopy (RCM) in the differential diagnosis of hypopigmented mycosis fungoides (HMF) and vitiligo.Methods: Cases with persistent hypopigmented patches, suspicious of early stage vitiligo, or HMF were imaged with RCM. The melanin contents and inflammatory conditions of the epidermis and superficial dermis of the lesions were compared with the same layers of the adjacent skin, and then, the imaged lesions were biopsied and analyzed by histology.Results: 15 cases were enrolled in this study, and based on the RCM findings, there was just slight or moderate reduction of melanin but no melanin absence in the basal cell layer of HMF lesions. The finding of monomorphous weakly refractile, oval to round cells on the basis of vesicle-like dark space was clearly elucidated in the epidermis of the lesions by RCM, which indicates the Pautrier's microabscesses on histopathology. Among those 15 cases, 13 cases were identified as HMF, and the other two cases were vitiligo, based on RCM findings, which were confirmed by histology analysis.Conclusions: The RCM findings correlated well with histology results in the screening of HMF, which indicates the RCM is an important tool in the early detection and differential diagnosis of HMF.

Role of Reflectance Confocal Microscopy in Cryosurgery

Cryosurgery ◽  
2014 ◽  
pp. 173-183
Author(s):  
Joseph Chao ◽  
Rainer Hofmann-Wellenhof ◽  
Clara Curiel-Lewandrowski
Keyword(s):  
Confocal Microscopy ◽  
Reflectance Confocal Microscopy
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