Flat‐pigmented facial lesions without highly specific melanocytic dermoscopy features: the role of dermoscopic globules and dots in differential diagnosis with corresponding reflectance confocal microscopy substrates

2019 ◽  
Vol 34 (3) ◽  
Author(s):  
S. Guida ◽  
F. Farnetani ◽  
B. De Pace ◽  
S. Kaleci ◽  
J. Chester ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Confocal Microscopy ◽  
Reflectance Confocal Microscopy

scholarly journals The Differential Diagnosis of Hypopigmented Mycosis Fungoides and Vitiligo With Reflectance Confocal Microscopy: A Preliminary Study

2021 ◽  
Vol 7 ◽  
Author(s):  
Huaxu Liu ◽  
Leilei Wang ◽  
Yan Lin ◽  
Xiaofeng Shan ◽  
Min Gao
Keyword(s):  
Differential Diagnosis ◽  
Confocal Microscopy ◽  
Mycosis Fungoides ◽  
Early Stage ◽  
Reflectance Confocal Microscopy ◽  
Inflammatory Conditions ◽  
Dark Space ◽  
Superficial Dermis ◽  
Melanin Contents

Objective: To investigate the role of reflectance confocal microscopy (RCM) in the differential diagnosis of hypopigmented mycosis fungoides (HMF) and vitiligo.Methods: Cases with persistent hypopigmented patches, suspicious of early stage vitiligo, or HMF were imaged with RCM. The melanin contents and inflammatory conditions of the epidermis and superficial dermis of the lesions were compared with the same layers of the adjacent skin, and then, the imaged lesions were biopsied and analyzed by histology.Results: 15 cases were enrolled in this study, and based on the RCM findings, there was just slight or moderate reduction of melanin but no melanin absence in the basal cell layer of HMF lesions. The finding of monomorphous weakly refractile, oval to round cells on the basis of vesicle-like dark space was clearly elucidated in the epidermis of the lesions by RCM, which indicates the Pautrier's microabscesses on histopathology. Among those 15 cases, 13 cases were identified as HMF, and the other two cases were vitiligo, based on RCM findings, which were confirmed by histology analysis.Conclusions: The RCM findings correlated well with histology results in the screening of HMF, which indicates the RCM is an important tool in the early detection and differential diagnosis of HMF.

scholarly journals Imaging of Vulva Syringoma With Reflectance Confocal Microscopy

2021 ◽  
Vol 8 ◽  
Author(s):  
Lin Feng ◽  
Yan Lin ◽  
Leilei Wang ◽  
Hongxiao Chen ◽  
Min Gao ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Confocal Microscopy ◽  
Potential Role ◽  
Reflectance Confocal Microscopy ◽  
Histological Evaluation ◽  
Histological Findings ◽  
Dark Line ◽  
Confocal Images ◽  
Distinct Features

Objectives: To investigate the application of reflectance confocal microscopy (RCM) imaging in diagnosis of vulva syringoma.Methods: Patients with lesions suspicious of syringoma on vulva were enrolled in the study. After informed consent was taken, the lesions were photographed and imaged with RCM. The features of the lesion in confocal images were then analyzed and compared with the biopsy findings for histology correlation.Results: Eleven cases in total were included in the study. The typical RCM features observed in syringoma are the presence of round to oval high refractive, and relatively monomorphous mass of varying sizes in the superficial and middle dermis, usually surrounded with 1–2 layers of light-dark line structures, which were further confirmed by histological evaluation. Ten cases showed classic features of syringoma and 1 case exhibited milia in RCM images.Conclusions: Syringoma has distinct features in RCM imaging, which correlates well with histological findings, highlighting the potential role of RCM in the diagnosis and differential diagnosis of vulva syringoma.

Treatment of Extramammary Paget Disease and the Role of Reflectance Confocal Microscopy: A Prospective Study

2021 ◽  
Vol 47 (4) ◽  
pp. 473-479
Author(s):  
Cristian Navarrete-Dechent ◽  
Saud Aleissa ◽  
Miguel Cordova ◽  
Brian P. Hibler ◽  
Andres M. Erlendsson ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Prospective Study ◽  
Reflectance Confocal Microscopy ◽  
Paget Disease ◽  
A Prospective Study

Role of Reflectance Confocal Microscopy in Cryosurgery

Cryosurgery ◽  
2014 ◽  
pp. 173-183
Author(s):  
Joseph Chao ◽  
Rainer Hofmann-Wellenhof ◽  
Clara Curiel-Lewandrowski
Keyword(s):  
Confocal Microscopy ◽  
Reflectance Confocal Microscopy

The differential diagnosis of syringoma and milia based on the imaging of reflectance confocal microscopy

2020 ◽  
Vol 26 (6) ◽  
pp. 951-953
Author(s):  
Min Gao ◽  
Yan Lin ◽  
Leilei Wang ◽  
Yongmei Yu ◽  
Yan Zhou ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Confocal Microscopy ◽  
Reflectance Confocal Microscopy

The potential role of in vivo reflectance confocal microscopy for evaluating oral cavity lesions: a systematic review

2016 ◽  
Vol 45 (10) ◽  
pp. 723-729 ◽  
Author(s):  
Alberta Lucchese ◽  
Enrica Gentile ◽  
Antonio Romano ◽  
Claudio Maio ◽  
Luigi Laino ◽  
...  
Keyword(s):  
Systematic Review ◽  
Confocal Microscopy ◽  
Oral Cavity ◽  
Potential Role ◽  
Reflectance Confocal Microscopy
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