scholarly journals Reflectance Confocal Microscopy of Pigmented Bowen’s Disease: A Case Series of Difficult to Diagnose Lesions

2020 ◽  
Vol 12 (2) ◽  
pp. 98-106
Author(s):  
Sara Mazzilli ◽  
Reyes Gamo-Villegas ◽  
Ana Pampin-Franco ◽  
Jose Luis Lopez Estebaran ◽  
Fernando Pinedo ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Cell Carcinoma ◽  
Histopathological Examination ◽  
Case Series ◽  
The Body ◽  
Reflectance Confocal Microscopy ◽  
Bowen’S Disease ◽  
Seborrheic Keratosis ◽  
Bowen's Disease ◽  
Precise Diagnosis

Pigmented Bowen’s disease is a rare variant of in situ squamous skin cell carcinoma. It mainly affects patients between 60 and 70 years of age. Its clinical features include well-demarcated, pigmented plaque arising in photo-exposed areas of the body. The best-characterized feature of the disease by histological examination is the presence of atypical keratinocytes, hyperpigmentation of the epidermis with trans-epidermal elimination of melanin and dermal melanophages. Precise diagnosis is often difficult, both clinically and dermoscopically, as Bowen’s disease is often mistaken with keratinocyte tumors such as solar lentigines, seborrheic keratosis, Bowenoid papulosis, pigmented basal cell carcinoma, pigmented actinic keratosis; or even melanocytic lesions such as melanocytic nevus, pigmented epithelioid melanocytoma, and melanoma. Precise diagnosis often requires biopsy and histopathological examination of the tissue. Reflectance confocal microscopy is a noninvasive technique to diagnose pigmented skin lesions. To date, not much data are available regarding its use in the diagnosis of pigmented Bowen’s disease. Herein, we report a well-represented case series of pigmented Bowen’s disease imaged using dermoscopy and reflectance confocal microscopy.

Reflectance confocal microscopy of Pigmented Bowen's disease: misleading dendritic cells

2016 ◽  
Vol 23 (1) ◽  
pp. 126-128 ◽  
Author(s):  
S. Debarbieux ◽  
J. L. Perrot ◽  
E. Cinotti ◽  
B. Labeille ◽  
J. Fontaine ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Confocal Microscopy ◽  
Reflectance Confocal Microscopy ◽  
Bowen’S Disease ◽  
Bowen's Disease

scholarly journals Behavioral factors associated with the development of skin cancer in patients of arsenicosis

2018 ◽  
Vol 11 (2) ◽  
pp. 103
Author(s):  
Towhida Noor ◽  
Md. Shahidullah Sikder ◽  
Lubna Khondker ◽  
Mohammed Saiful Islam Bhuiyan ◽  
Tanvir Rahman
Keyword(s):  
Skin Cancer ◽  
Cell Carcinoma ◽  
Sun Exposure ◽  
The Body ◽  
Case Group ◽  
Skin Carcinoma ◽  
Bowen’S Disease ◽  
Behavioral Factors ◽  
Bowen's Disease ◽  
Factors Associated

<p>The study was conducted to evaluate the behavioral factors associated with the development of skin cancer in arsenicosis patients. Arsenicosis patients without skin cancer were taken as control. In the sun-exposed area of the body, 57.2% of skin carcinoma was Bowen’s disease. In the covered area of the body, 56.0% was Bowen’s disease, 36% was squamous cell carcinoma and 8% was basal cell carcinoma. Again, 53.1% of case and 59.4% of control never used fertilizer and pesticide. The majorities were non-smoker (case 53.1%, control 59.3%). Mean cumulative sun exposure was more in the case group (5853.9 ± 2219.7 hours) than in the control group (2219 ± 392.4 hours) and the rate of sun exposure was also higher in the case group. In conclusion, sun exposure was significantly higher in carcinoma patients and since most of the lesions were in the covered areas of the body, it can be said that these carcinomas were due to arsenicosis and not due to sun exposure and smoking status, use of fertilizer and pesticides were not associated with the development of skin carcinoma.</p>

scholarly journals Clinical and Pathological Characteristics of 755 Patients with Skin Cancers in Hainan, China: A 12-Year Retrospective Study

2021 ◽  
Author(s):  
Lengbing Sun ◽  
Jiejie Lu ◽  
Ming Zhang ◽  
Xianxu Yang ◽  
Weiwei Wu ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Histopathological Examination ◽  
Neck Region ◽  
Pathological Diagnosis ◽  
Bowen’S Disease ◽  
Malignant Tumours ◽  
Bowen's Disease ◽  
Pathological Characteristics ◽  
Skin Cancers ◽  
Common Skin

Abstract Background: Skin cancers are the most frequent types of all malignant tumours with increasing incidence rates worldwide. Objectives: This study aimed to analyze the clinical–pathological characteristics of skin cancers in patients visited at the Department of Dermatology of the Fifth People's Hospital of Hainan Province from China during the last 12 years. Methods: The hospital database was searched for patients with skin cancers over a period of 12 years ( from January 1, 2009 to December 31, 2020) , and a retrospective review was conducted and a descriptive data analysis was undertaken on patients. Results: A total of 755 specimens of skin cancers were confirmed during this period, of which 696 (92.19%) were common skin cancers and of which 59(7.81%) were rare skin cancers. The incidence is on the rise year by year, with a marked decline in 2020. The common skin cancers were basal cell carcinoma (341, 48.99%), followed by squamous cell carcinoma (148 , 21.26%) and Bowen’s disease (109, 15.66%) . The range of age at the time of skin cancers was from 40 to 79 years (73.01% ). Males and females showed an almost similar incidence. The duration ranged from 7 days to 70 years, mainly occurred in 2 years( 53.30% ). The head, face and neck region were the most frequent location (452, 59.87% ), followed by extremity (107, 14.17% ) and trunk (87, 11.52% ). The accordance rates of clinical-pathological diagnosis in common skin cancers was about 43.14% , while that of rare skin cancers such as skin appendages was only 27.59% .Conclusions: Overall, head, face and neck region was the most common site for sun-related skin cancers in Hainan, China. BCC was the most common skin cancer followed by SCC and Bowen's disease. Moreover, skin cancers has a low coincidence rate of clinical-pathological diagnosis. Consequently, any suspicious lesion, for which the clinical diagnosis is uncertain, should be biopsied for histopathological examination to rule out malignancy.

scholarly journals Concurrent Bowen’s Disease of the Nipple and Breast Cancer

2020 ◽  
Vol 13 (3) ◽  
pp. 1410-1414
Author(s):  
Kei Yamaguchi ◽  
Ryoichi Matsunuma ◽  
Toko Kumeta ◽  
Sae Imada ◽  
Ryosuke Hayami ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Squamous Cell Carcinoma ◽  
Carcinoma In Situ ◽  
Histopathological Examination ◽  
Careful Examination ◽  
Bowen’S Disease ◽  
Ipsilateral Breast ◽  
Surgical Specimen ◽  
Bowen's Disease

Bowen’s disease is a squamous cell carcinoma in situ that commonly develops on the trunk, arms, or legs and has not spread beyond the top layer of skin. It seldom develops on the nipple. We report a patient who presented with Bowen’s disease of the nipple and had a concurrent breast cancer identified in the ipsilateral breast after careful examination. Histopathological examination of the surgical specimen after mastectomy confirmed the diagnoses.

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