scholarly journals Introductory Chapter: Gastric Cancer in the Past and Our Days

2017 ◽  
Author(s):  
Gyula Mózsik ◽  
Oszkár Karádi
Keyword(s):  
Author(s):  
Matthew D. O'Hara

This introductory chapter provides an overview of the analysis of time experience and futuremaking through historical case studies in colonial Mexico. Colonial Mexico developed a culture of innovation, human aspiration, and futuremaking that was subsequently forgotten in part because it did not fit with later definitions of modernity and innovation as secular phenomena and things untethered to the past or tradition. This choice of historical method and topics is driven by a desire to step outside some of the dominant paradigms in the study of Latin America and colonialism in general. Examining the relationship between past, present, and future offers a way to reconsider Mexico's colonial era, its subsequent historical development, and how people have understood that history.


Author(s):  
Joanna D. Haigh ◽  
Peter Cargill

This introductory chapter provides an overview of the Earth's climate system—its composition, structure, and circulation—and some of the ways in which these vary naturally with time. It examines the key features of the structure of the Sun, its magnetic field, atmosphere, and its emission of radiation and particles. A comprehension of how the sun affects the Earth is a fundamental requirement for understanding how climate has varied in the past and how it might change in the future. This is particularly important in the context of determining the cause(s) of climate change and understanding natural factors in order to be able to attribute to human activity any past or potential future influence on a range of timescales.


2020 ◽  
pp. 1-14
Author(s):  
Arash Ansari ◽  
David N. Osser

This introductory chapter notes the development and increased use of psychiatric medications over the past 70 years. It introduces the reader to the topics that are discussed in the subsequent chapters of this book. It reviews the differences between efficacy studies and effectiveness studies and how evidence gained from these studies can inform clinical knowledge. The availability of practice guidelines and algorithms are noted as well. This chapter also lists clinical variables that need to be taken into account before selecting any psychiatric medicine. Finally, it notes the importance of learning about the use of psychotropic medications in women of childbearing potential and during breastfeeding.


2019 ◽  
Vol 156 (6) ◽  
pp. S-1079
Author(s):  
Paul T. Kroner ◽  
Alex M. Kesler ◽  
Peter Abader ◽  
Victor Ciofoaia ◽  
Joo Ha Hwang ◽  
...  

Author(s):  
Jeffrey Jensen Arnett

This chapter provides an introduction to the Oxford Handbook of Emerging Adulthood. It begins with an overview of the aims and scope of the handbook. Then it summarizes briefly the content of the chapters to come. The handbook is comprised of 35 chapters organized into 10 parts, with each part containing from two to six chapters. The chapters cover a broad range of areas, from structural factors (such as social class) to relationships (from family to friends) to risk and resilience. The final section of this introductory chapter presents suggestions for the future of the field. The explosive expansion of the field over the past 15 years is noted, and suggestions are made for the field to focus more on EAs who do not attend college, devote more research to international variations in EA, and examine the transition from EA to the next life stage.


2019 ◽  
Vol 7 (9) ◽  
pp. 305 ◽  
Author(s):  
Yanagi ◽  
Nishikawa ◽  
Shimokuri ◽  
Shuto ◽  
Takagi ◽  
...  

: Epstein–Barr virus (EBV) is a ubiquitous human herpes virus, but related with several types of malignancies. Among EBV-related malignancies, EBV-associated gastric carcinoma (EBVaGC) has the largest patient’s number. We screened for EBV infection in 1067 GC lesions of 1132 patients who underwent surgical resection from 2007 to 2017 in Japan and examined clinicopathological features of EBVaGC. EBV infection was detected by in situ hybridization with EBV-encoded small RNA 1(EBER-1 ISH). EBV was infected in 80 GC lesions (7.1%). Mean age was significantly lower in patients with EBVaGC than with EBV-negative GC. EBVaGC was more frequent in men than in women. EBVaGC was found twice as frequent in the upper or middle stomach as in the lower stomach. Early EBVaGC was more frequent, and submucosally invaded cases were dominant. The presence of lymphatic vessel invasion was less in EBVaGC, but frequency of lymph node metastasis was similar. Carcinoma with lymphoid stroma (CLS) was found in 3.8% (43/1132) of all lesions with 60.5% of EBV positivity. The synchronous or metachronous multiple GC was frequent in EBVaGC. We clarified clinicopathologic characteristics of EBVaGC over the past decade in Japan. EBV infection should be examined in gastric cancer cases showing these characteristics.


2012 ◽  
Vol 30 (19) ◽  
pp. 2297-2299 ◽  
Author(s):  
Gabriel A. Brooks ◽  
Peter C. Enzinger ◽  
Charles S. Fuchs

Onco ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 140-157
Author(s):  
Bruno Takao Real Karia ◽  
Camila Albuquerque Pinto ◽  
Carolina Oliveira Gigek ◽  
Fernanda Wisnieski ◽  
Marilia Arruda Cardoso Smith

Gastric cancer is one of the most common cancers and the third cause of cancer-related death worldwide. The treatment of GC patients improved due to advancements in surgery, radiotherapy and chemotherapy. However, the long-term survival rate of patients with gastric cancer remains around 20%. Thus, development of novel therapeutic approaches is of great interest, in order to reduce the need for mutilating surgeries and morbid adjuvant therapies. For many years, it was believed that the RNA was a mere intermediate molecule in the genetic information flow. However, during the past decades, with the advent of new sequencing technologies, it was revealed that non-coding RNAs play important roles in many different biological processes. The Wnt/β-catenin signaling pathway has been reported to regulate crucial events during neoplasic development, such as cell differentiation, proliferation, invasion, migration, apoptosis, and angiogenesis. In this review, we will focus on microRNAs and long non-coding RNAs that have been implicated in gastric cancer tumorigenesis via modulation of the Wnt/β-catenin signaling pathway, which provided some biomarkers to prognosis, diagnosis, and therapy.


Author(s):  
Muhammad O. Awiwi ◽  
Rochita V. Ramanan ◽  
Mohamed Elshikh ◽  
Raghunandan Vikram

AbstractGastric cancer is one of the leading causes of death from malignancy. Despite the enormous advancement in medical oncology over the past decade, surgical resection of early tumors remains the most effective treatment. Accurate interpretation of radiologic imaging studies is crucial for staging local disease spread, predicting possible lymphatic involvement, and identifying metastatic disease, thereby guiding management plans. This article reviews imaging patterns of the normal stomach along with appearances of gastric cancer, its local spread patterns and distant metastasis, and also describes key features pertaining to preoperative staging.


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