scholarly journals Operated patients with gastric cancer cases on during the past fifty years.

2002 ◽  
Vol 63 (4) ◽  
pp. 797-806
Author(s):  
Shuhei HIROSE
Keyword(s):  
Gastric Cancer ◽  
The Past

scholarly journals Tu1656 – Gastric Cancer and Geographical/Ethnic Shifts in the United States in the Past Decade

2019 ◽  
Vol 156 (6) ◽  
pp. S-1079
Author(s):  
Paul T. Kroner ◽  
Alex M. Kesler ◽  
Peter Abader ◽  
Victor Ciofoaia ◽  
Joo Ha Hwang ◽  
...  
Keyword(s):  
United States ◽  
Gastric Cancer ◽  
The United States ◽  
The Past

scholarly journals Clinicopathologic Characteristics of Epstein–Barr Virus-Associated Gastric Cancer Over the Past Decade in Japan

2019 ◽  
Vol 7 (9) ◽  
pp. 305 ◽  
Author(s):  
Yanagi ◽  
Nishikawa ◽  
Shimokuri ◽  
Shuto ◽  
Takagi ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Epstein Barr Virus ◽  
Clinicopathologic Characteristics ◽  
Barr Virus ◽  
Ebv Infection ◽  
The Past ◽  
Lymphoid Stroma ◽  
Human Herpes Virus ◽  
Epstein Barr

: Epstein–Barr virus (EBV) is a ubiquitous human herpes virus, but related with several types of malignancies. Among EBV-related malignancies, EBV-associated gastric carcinoma (EBVaGC) has the largest patient’s number. We screened for EBV infection in 1067 GC lesions of 1132 patients who underwent surgical resection from 2007 to 2017 in Japan and examined clinicopathological features of EBVaGC. EBV infection was detected by in situ hybridization with EBV-encoded small RNA 1(EBER-1 ISH). EBV was infected in 80 GC lesions (7.1%). Mean age was significantly lower in patients with EBVaGC than with EBV-negative GC. EBVaGC was more frequent in men than in women. EBVaGC was found twice as frequent in the upper or middle stomach as in the lower stomach. Early EBVaGC was more frequent, and submucosally invaded cases were dominant. The presence of lymphatic vessel invasion was less in EBVaGC, but frequency of lymph node metastasis was similar. Carcinoma with lymphoid stroma (CLS) was found in 3.8% (43/1132) of all lesions with 60.5% of EBV positivity. The synchronous or metachronous multiple GC was frequent in EBVaGC. We clarified clinicopathologic characteristics of EBVaGC over the past decade in Japan. EBV infection should be examined in gastric cancer cases showing these characteristics.

Adjuvant Therapy for Gastric Cancer: Revisiting the Past to Clarify the Future

2012 ◽  
Vol 30 (19) ◽  
pp. 2297-2299 ◽  
Author(s):  
Gabriel A. Brooks ◽  
Peter C. Enzinger ◽  
Charles S. Fuchs
Keyword(s):  
Gastric Cancer ◽  
Adjuvant Therapy ◽  
The Past ◽  
The Future

scholarly journals Non-Coding RNAs and Wnt/β-Catenin Signaling Pathway in Gastric Cancer: From EMT to Drug Resistance

Onco ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 140-157
Author(s):  
Bruno Takao Real Karia ◽  
Camila Albuquerque Pinto ◽  
Carolina Oliveira Gigek ◽  
Fernanda Wisnieski ◽  
Marilia Arruda Cardoso Smith
Keyword(s):  
Gastric Cancer ◽  
Signaling Pathway ◽  
Biological Processes ◽  
Therapeutic Approaches ◽  
Term Survival ◽  
The Third ◽  
The Past ◽  
Sequencing Technologies ◽  
Non Coding Rnas

Gastric cancer is one of the most common cancers and the third cause of cancer-related death worldwide. The treatment of GC patients improved due to advancements in surgery, radiotherapy and chemotherapy. However, the long-term survival rate of patients with gastric cancer remains around 20%. Thus, development of novel therapeutic approaches is of great interest, in order to reduce the need for mutilating surgeries and morbid adjuvant therapies. For many years, it was believed that the RNA was a mere intermediate molecule in the genetic information flow. However, during the past decades, with the advent of new sequencing technologies, it was revealed that non-coding RNAs play important roles in many different biological processes. The Wnt/β-catenin signaling pathway has been reported to regulate crucial events during neoplasic development, such as cell differentiation, proliferation, invasion, migration, apoptosis, and angiogenesis. In this review, we will focus on microRNAs and long non-coding RNAs that have been implicated in gastric cancer tumorigenesis via modulation of the Wnt/β-catenin signaling pathway, which provided some biomarkers to prognosis, diagnosis, and therapy.

scholarly journals Imaging of Gastric Carcinoma. Part One: Diagnosis and Staging

2021 ◽  
Author(s):  
Muhammad O. Awiwi ◽  
Rochita V. Ramanan ◽  
Mohamed Elshikh ◽  
Raghunandan Vikram
Keyword(s):  
Gastric Cancer ◽  
Causes Of Death ◽  
Medical Oncology ◽  
Preoperative Staging ◽  
Disease Spread ◽  
The Past ◽  
Local Spread ◽  
Radiologic Imaging ◽  
Management Plans ◽  
Normal Stomach

AbstractGastric cancer is one of the leading causes of death from malignancy. Despite the enormous advancement in medical oncology over the past decade, surgical resection of early tumors remains the most effective treatment. Accurate interpretation of radiologic imaging studies is crucial for staging local disease spread, predicting possible lymphatic involvement, and identifying metastatic disease, thereby guiding management plans. This article reviews imaging patterns of the normal stomach along with appearances of gastric cancer, its local spread patterns and distant metastasis, and also describes key features pertaining to preoperative staging.

scholarly journals Comparison of laparoscopic total gastrectomy and laparotomic total gastrectomy for gastric cancer

2015 ◽  
Vol 28 (1) ◽  
pp. 65-69 ◽  
Author(s):  
Carlos Alexandre Garção RAMAGEM ◽  
Marcelo LINHARES ◽  
Croider Franco LACERDA ◽  
Paulo Anderson BERTULUCCI ◽  
Durval WONRATH ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Total Gastrectomy ◽  
Point Of View ◽  
Surgical Time ◽  
Oncological Safety ◽  
The Past ◽  
Significant Difference ◽  
Degree Of Differentiation ◽  
Comparison Data

BACKGROUND: The use of laparoscopy for the treatment of gastric cancer suffered some resistance among surgeons around the world, gaining strength in the past decade. However, its oncological safety and technical feasibility remain controversial. AIM: To describe the results from the clinical and anatomopathological point of view in the comparative evaluation between the surgical videolaparoscopic and laparotomic treatments of total gastrectomy with linphadenectomy at D2, resection R0. METHOD: Retrospective analyses and comparison data from patients submitted to total gastrectomy with D2 linphadenectomy at a sole institution. The data of 111 patients showed that 64 (57,7%) have been submitted to laparotomic gastrectomy and 47 (42,3%) to gastrectomy entirely performed through videolaparoscopy. All variables related to the surgery, post-operative follow-up and anatomopathologic findings have been evaluated. RESULTS: Among the studied variables, videolaparoscopy has shown a shorter surgical time and a more premature period for the introduction of oral and enteral nourishment than the open surgery. As to the amount of dissected limph nodes, there has been a significant difference towards laparotomy with p=0,014, but the average dissected limph nodes in both groups exceed 25 nodes as recommended by the JAGC. Was not found a significant difference between the studied groups as to age, ASA, type of surgery, need for blood transfusion, stage of the disease, Bormann classification, degree of differentiation, damage of the margins, further complications and death. CONCLUSION: The total gastrectomy with D2 lymphadenectomy performed by laparoscopy presented the same benefits known of laparotomy and with the advantages already established of minimally invasive surgery. It was done with less surgical time, less time for re-introduction of the oral and enteral diets and lower hospitalization time compared to laparotomy, without increasing postoperative complications.

Smoking Status and Gastric Cancer Risk: An Updated Meta-Analysis of Case-Control Studies Published in the past Ten Years

2009 ◽  
Vol 95 (1) ◽  
pp. 13-22 ◽  
Author(s):  
Giuseppe La Torre ◽  
Giacomina Chiaradia ◽  
Francesco Gianfagna ◽  
Angelo De Lauretis ◽  
Stefania Boccia ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Risk ◽  
Smoking Status ◽  
Meta Analysis ◽  
Case Control ◽  
Gastric Cancer Risk ◽  
Case Control Studies ◽  
The Past

scholarly journals Adjuvant Chemoradiation Therapy in Gastric Cancer: Critically Reviewing the Past and Visualizing the Next Step Forward

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Konstantinos Papadimitriou ◽  
Georgios Antoniou ◽  
Christian Rolfo ◽  
Antonio Russo ◽  
Giuseppe Bronte ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Surgical Treatment ◽  
Literature Review ◽  
Combined Therapy ◽  
Chemoradiation Therapy ◽  
Potential Bias ◽  
Adjuvant Chemoradiation ◽  
The Past ◽  
Pros And Cons ◽  
Chemoradiation Treatment

Gastric cancer remains one of the most common malignancies worldwide. Despite the significant advances in surgical treatment and multimodality strategies, prognosis has modestly improved over the last two decades. Locoregional relapse remains one of the main issues and the combined chemoradiation treatment seems to be one of the preferred approaches. However, more than ten years after the hallmark INT-0116 trial, minimal progress has been made both in terms of effectiveness and toxicity. Moreover, new regimens added to combined therapy failed to prove favourable results. Herein, we attempt a thorough literature review comparing pros and cons of all relative studies and potential bias, targeting well-designed future approaches.

scholarly journals 1418P Chronological improvement in the survival of advanced gastric cancer patients in the past 15 years

2021 ◽  
Vol 32 ◽  
pp. S1064
Author(s):  
T. Ogata ◽  
Y. Narita ◽  
R. Kumanishi ◽  
T. Nakazawa ◽  
Y. Matsubara ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Advanced Gastric Cancer ◽  
Cancer Patients ◽  
The Past ◽  
Gastric Cancer Patients
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