One-Day Session LINAC–Based Stereotactic Radiosurgery of Posterior Uveal Melanoma

2012 ◽  
Vol 22 (2) ◽  
pp. 226-235 ◽  
Author(s):  
Alena Furdova ◽  
Peter Strmen ◽  
Iveta Waczulikova ◽  
Martin Chorvath ◽  
Miron Sramka ◽  
...  
2014 ◽  
Vol 132 (3) ◽  
pp. 367
Author(s):  
Joshua T. McKenzie ◽  
Michelle L. Mierzwa

2020 ◽  
Vol 50 (3) ◽  
pp. 156-162
Author(s):  
Gökçen Özcan ◽  
Ahmet Kaan Gündüz ◽  
İbadulla Mirzayev ◽  
Kaan Oysul ◽  
Hasan Uysal

2009 ◽  
Vol 74 (6) ◽  
pp. 558-562 ◽  
Author(s):  
Ian Rennie ◽  
David Forster ◽  
Andras Kemeny ◽  
Lee Walton ◽  
Ian Kunkler

2020 ◽  
Vol 76 (1) ◽  
pp. 46-51
Author(s):  
Pavlína Zahorjanová ◽  
Ján Sekáč ◽  
Pavel Babál ◽  
Michal Štubňa

Introduction: In the past enucleation was the treatment of choice for all the patients with uveal melanoma. Nowadays, we prefer glope-sparing treatment modalities, except for large tumors, tumors with extrascleral extension and painful blind eyes. Most of the patients perform radiotherapy or local resection techniques. In Slovak Republic, the only one possibility is a stereotactic radiotherapy on a linear accelerator LINAC. Nevertheless, enucleation after radiotherapy is necessary for some patients. The causes are postradiation complications, mainly neovascular glaucoma, tumor recurrence, tumor progression or patient´s decision. Material and methods: The retrospective non-randomised study of 168 eyes of the patients with choroidal or ciliary body melanoma, who performed one-day session stereotactic radiosurgery at the linear accelerator LINAC during period 2007-2016. The data about postradiation complications were analysed based on the medical records of the patients and the data about enucleated eyes based on the histopathological findings. Results: The occurence of enucleation after radiotherapy in our cohort was 17 % (28 patients), with median time period after radiotherapy 21,5 months. The most common cause was neovascular glaucoma (82 %), then tumor progression (14 %) and patient´s decision (4 %). The most common histopathological finding was spindle-cell melanoma. Discussion: Others authors describe similar enucleation rate and causes. The histopathological findings indentified more viable melanoma cells in eyes enucleated for tumor progression in comparison with enucleation for other causes. Enucleation may be more difficult and the occurence of postoperative complications can be higher in the eyes after radiotherapy rather than primary enucleation. Conclusion: The management of the patients with uveal melanoma is difficult, and requires the cooperation of ophthalmologist, oncologist, radiation physicist and pathologist. Even if we make effort to preserve the eye, enucleation after radiotherapy is necessary in some patients.


2007 ◽  
Vol 85 (2-3) ◽  
pp. 106-112 ◽  
Author(s):  
Achilles J. Fakiris ◽  
Simon S. Lo ◽  
Mark A. Henderson ◽  
Thomas C. Witt ◽  
Robert M. Worth ◽  
...  

2013 ◽  
Vol 131 (5) ◽  
pp. 630 ◽  
Author(s):  
Daniela Suesskind ◽  
Jutta Scheiderbauer ◽  
Markus Buchgeister ◽  
Michael Partsch ◽  
Wilfried Budach ◽  
...  

2021 ◽  
Author(s):  
Kristina Horkovicova ◽  
Alena Furdova

Currently, melanoma of uvea is the most well-known essential tumor, which is intaocular and malignant. Treatment using radiation has now supplanted enucleation as the therapy of decision. Radioactive eye plaques and treatment using proton are being the two most examined radiotherapeutic modalities. All the more as of late, stereotactic radiosurgery and fractionated stereotactic radiotherapy have risen as promising, non-intrusive medicines for uveal melanoma. Technique called stereotactic radiosurgery might be viewed as like „not surgery” on the grounds no extractions are included. All things being equal, it is a serious strategy for radiation treatment that conveys high dosages of radiation to exceptionally little territories and volumes.


Author(s):  
Alena Furdova ◽  
Adriana Furdova ◽  
Miron Sramka ◽  
Robert Furda ◽  
Gabriel Kralik

1996 ◽  
Vol 66 (1) ◽  
pp. 208-213 ◽  
Author(s):  
G. Marchini ◽  
M. Gerosa ◽  
E. Piovan ◽  
A. Pasoli ◽  
S. Babighian ◽  
...  

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