COPPER ACCUMULATION IN THE LIVER OF SHEEP AND CATTLE FED DIETS SUPPLEMENTED WITH COPPER SULFATE OR COPPER CHLORIDE

1990 ◽  
Vol 70 (2) ◽  
pp. 727-730 ◽  
Author(s):  
M. IVAN ◽  
J. G. PROULX ◽  
R. MORALES ◽  
H. C. V. CODAGNONE ◽  
M. DE S. DAYRELL

Six groups of 12 pregnant cows were fed barley or grass silage with or without copper sulfate or copper chloride supplements (16 or 14 mg copper kg−1 dry matter (DM)). In addition, five groups of 10 lambs were fed diets supplemented with 5 or 10 mg Cu kg−1 DM as salts of sulfate or chloride. The two Cu salts produced equal increases in the concentration of Cu in the livers of both sheep and cattle. Key words: Sheep, cattle, liver, copper sulfate, copper chloride

1983 ◽  
Vol 63 (4) ◽  
pp. 861-869 ◽  
Author(s):  
D. M. VEIRA ◽  
A. FORTIN ◽  
M. IVAN ◽  
G. BUTLER ◽  
J. G. PROULX

Over a 2-yr period, 44 bulls and 44 implanted steers of Hereford × Shorthorn breeding were fed, from weaning to slaughter, diets of grass silage with 0, 0.45, 0.9 or 1.35 kg barley dry matter (DM)/100 kg liveweight. Each animal was slaughtered when it had 8 mm of fat over the loin as determined by ultrasound measurement. As the level of barley in the diet increased the rate of gain increased (P < 0.01), as did DM intake (P < 0.05) while feed required per kilogram gained and days on feed decreased. Bulls and steers responded in a similar manner to the different diets. Bulls gained faster (P < 0.01) on similar intakes of DM with the result that feed required for kilogram gain was less for bulls (P < 0.05). There was no difference (P > 0.05) in days to market for bulls and steers. There was no consistent effect of diet on carcass characteristics. However, castration resulted in lighter (P < 0.01) slaughter and carcass weights as well as a smaller (P < 0.01) rib eye area. Key words: Cattle, castration, diet, growth, carcass


1981 ◽  
Vol 61 (3) ◽  
pp. 613-624 ◽  
Author(s):  
W. T. BUCKLEY ◽  
R. M. TAIT

Blood chemistry of lambs was studied during the period of liver copper accumulation in chronic copper toxicity. In trial 1, dietary copper was 10.9, 17.8 and 25.2 mg/kg. During a 10-wk feeding trial no mortalities due to copper toxicity and no differences in growth rate were found (P > 0.05). At slaughter, liver copper levels were 239, 454 and 721 μg/g of dry matter, respectively (P < 0.05). There was no response to added dietary copper for hematocrit, ferroxidase, aspartate aminotransferase, allantoin, plasma protein, catalase, molybdenum or plasma copper (P > 0.05). In trial 2, dietary copper was 9.1 and 37.3 mg/kg. Lambs were individually fed for an 11-wk feeding trial. No mortalities or difference in growth occurred (P > 0.05). At slaughter, liver copper levels were 372 and 1109 μg/g of dry matter, respectively (P < 0.05). Plasma aspartate aminotransferase was elevated in response to added dietary copper (P < 0.05). No effect due to added dietary copper was found with superoxide dismutase, alkaline phosphatase, ferroxidase, lactate dehydrogenase, plasma protein, hemoglobin, plasma copper, calcium, inorganic phosphate, cholesterol, triglyceride, uric acid, urea nitrogen or hematocrit (P > 0.05). Only plasma aspartate aminotransferase and liver copper concentration could be considered useful indicators of high copper status.


1990 ◽  
Vol 70 (1) ◽  
pp. 313-317 ◽  
Author(s):  
D. M. VEIRA ◽  
J. G. PROULX ◽  
J. R. SEOANE

Forty crossbred beef steers were used in a 112-d experiment to study the effect of fish meal (FM, 300 g d−1), soybean meal (SBM, 320 g d−1), barley (B, 2 kg d−1) and B plus FM (2 kg + 300 g d−1) supplementation of grass silage on the performance of growing cattle. The growth rate of steers fed silage was 0.83 kg d−1 and this was increased by 0.15, 0.12, 0.27 and 0.36 kg d−1 by supplements of FM, SBM, B and B + FM. Silage dry matter (DM) intake averaged 2.13% of body weight. Protein supplementation had no effect on silage intake. B and B + FM supplementation increased total DM intake (P < 0.01), but decreased silage consumption by 14% (P < 0.05). Key words: Cattle, grass silage, soybean meal, barley, growth, fish meal


2020 ◽  
pp. 1098612X2096135
Author(s):  
Punyamanee Yamkate ◽  
Randi M Gold ◽  
Panagiotis G Xenoulis ◽  
Katja Steiger ◽  
David C Twedt ◽  
...  

Objectives The aim of this study was to assess hepatic copper concentrations and zonal distribution in cat liver specimens. Methods For this study, 121 archived, formalin-fixed, paraffin-embedded liver specimens from cats were used. Tissue sections were stained for copper with rhodanine and scored from 0 (no copper accumulation) to 5 (panlobular copper accumulation). The tissue specimens were then deparaffinized and hepatic copper concentrations were measured using flame atomic absorption spectroscopy. Results Tissue samples were categorized into four groups based on histopathologic findings: (1) no significant histopathologic hepatic changes (n = 66); (2) hepatic steatosis (n = 18); (3) inflammatory or infectious disease (n = 24); and (4) neoplasia (n = 13). Of the 121 specimens, 13 (11%) stained positive for copper, with three having a score ⩾3. Thirty-seven specimens (31%) had copper concentrations above the reference interval ([RI] <180 µg/g dry weight liver). Copper concentrations in cats with hepatic inflammatory or infectious disease were significantly higher than cats with hepatic steatosis ( P = 0.03). Copper-staining score and concentration were positively correlated ( rs = 0.46, P <0.001). Conclusions and relevance Despite the fact that 31% of specimens had copper concentrations above the RI, only 11% showed positive copper staining and only 2.5% had a score ⩾3. Our findings suggest that hepatic copper concentrations greater than the upper limit of the RI are relatively common in cats. Further studies to determine the factors that influence hepatic copper staining in cats and to establish contemporary RIs for hepatic copper in healthy cats are warranted.


Author(s):  
J.D. Leaver ◽  
R.C. Campling

Supplementary feeding of grazing dairy cows is often uneconomic, and whilst supplementation with silage (buffer feeding) can be worthwhile, this often leads to a depletion of winter forage stores. In this study, a mixture of brewers grains and treated straw was used as a supplement. Offered as a 1:1 mixture in the dry matter (DM), it is a purchased substitute for grass silage, having a similar cost, and similar metabolisable energy (ME) and crude protein (CP) contents. The high seasonality adjustments to milk price in mid-late season make supplementation potentially worthwhile.Experiments were carried out from April to September in 1988 and 1989, which had moderate and very low rainfall respectively. Each year 20 British Friesian cows which calved December to March (1988 experiment) and February-April (1989) were allocated at random to either treatment B or C. In B, the cows were offered a 1:1 mixture (DM basis) of brewers grains and NaOH treated chopped barley straw for 60 minutes after morning milking. In C, the cows received no supplement. Both groups were fed 1.0 kg/day of concentrates in the milking parlour. Due to the severe drought in 1989, concentrate feeding was increased to 5.0 kg/day for all cows during the last 4 weeks of the experiment. Also, urea-treated whole crop wheat was fed at a level of 2.5 kg DM/day during the last 7 days.


1983 ◽  
Vol 63 (1) ◽  
pp. 155-162 ◽  
Author(s):  
L. KUNG Jr. ◽  
B. W. JESSE ◽  
J. W. THOMAS ◽  
J. T. HUBER ◽  
R. S. EMERY

Whole barley was treated with sodium hydroxide (NaOH) in laboratory trials. Dry matter disappearance from nylon bags in the rumen of whole barley treated with 2.5, 3.5, or 4.9% NaOH for 30 h was 59.6, 72.4, and 93.0%, respectively, compared with 82.2% for untreated ground barley. In a subsequent lactation trial, 24 Holstein cows (eight per treatment) were fed high moisture ground ear corn, high moisture rolled barley or high moisture whole barley treated with 3.5% NaOH. Milk persistencies tended to be greater for cows fed high moisture rolled barley, next for ground ear corn and least for NaOH-treated barley. Milk composition was similar for all treatments. Dry matter intake was greatest for cows fed ground ear corn and lower for those fed the barley diets. Alpha-linked glucose and pH of feces were similar for cows fed ground ear corn and high moisture rolled barley diets, but fecal pH was lower and alpha-linked glucose concentrations three times greater for NaOH-treated barley. Digestibility percents of dry matter, acid detergent fiber and nitrogen were 61.4, 25.3, 64.7 for ground ear corn; 64.4, 38.0, 67.1 for high moisture rolled barley; and 56.8, 43.2, 54.8 for NaOH-treated barley, respectively. Rumen grain turnover estimated by excretion of ytterbium in feces was greatest for NaOH-treated barley (9.09%/h), intermediate for ground ear corn (6.10%/h) and lowest for high moisture rolled barley (4.93%/h). Key words: Dairy, sodium hydroxide, high moisture grains


1985 ◽  
Vol 65 (4) ◽  
pp. 897-903 ◽  
Author(s):  
D. M. VEIRA ◽  
M. IVAN ◽  
G. BUTLER ◽  
J. G. PROULX

Following weaning at 6–7 mo of age, 36 beef steers were used to determine production responses when grass silage was supplemented with barley or fishmeal. The silage was made from direct-cut, formic- acid-treated grass harvested from a mixed sward and had a high nitrogen content but poor fermentation characteristics. The silage was fed ad libitum for 98 days either alone or supplemented with 500 g fishmeal or 500 g barley per day. Both fishmeal and barley increased total dry matter intake (P < 0.01) by an amount equivalent to the quantity of supplement offered but had no effect on silage intake (P > 0.05). Steers fed the fishmeal grew substantially faster than either the barley (0.53 kg/day) or unsupplemented (0.54 kg/day) groups (P < 0.01). Fishmeal supplementation resulted in a large reduction (35%) in the amount of feed required per kilogram of gain. Key words: Cattle, grass silage, fishmeal, growth


2001 ◽  
Vol 137 (2) ◽  
pp. 205-220 ◽  
Author(s):  
A. F. CARSON ◽  
B. W. MOSS ◽  
L. E. R. DAWSON ◽  
D. J. KILPATRICK

The study investigated the effects of lamb genotype produced from hill flocks on feed efficiency, carcass characteristics and meat quality in animals finished on either a high forage:concentrate ratio diet (HFC) or a low forage:concentrate ratio diet (LFC). Purebred Scottish Blackface (BXB) lambs were compared with Blue-Faced Leicester×Scottish Blackface (BLXB) and Texel×Scottish Blackface (TXB) lambs. Purebred Cheviot (CXC), Suffolk×Cheviot (SXC) and Texel×Cheviot (TXC) lambs were also investigated. Lambs on the LFC diet were offered grass silage and concentrates mixed in the proportion of 0·80 silage and 0·20 concentrates on a dry matter basis. The LFC diet consisted of 0·20 grass silage and 0·80 concentrates on a dry matter basis. Representative lambs were slaughtered at the start of the experiment and on reaching 38 and 46 kg live weight. Averaged over the two slaughter weights, within the Blackface cross lambs, BXB had a lower liveweight gain (P < 0·01) than either BLXB or TXB (138, 207 and 203 (S.E. 11·1) g/day, respectively). Within the Cheviot cross lambs, CXC had a lower liveweight gain (P < 0·05) than SXC (188 v. 220 (S.E. 11·1) g/day), while SXC and TXC (204 g/day) had similar liveweight gains. Lambs on the LFC diet had a higher dressing proportion (P < 0·001) compared with lambs finished on the HFC diet (0·466 v. 0·434 (S.E. 0·0018) kg carcass per kg live weight). Averaged over the two slaughter weights BXB lambs had a lower (P < 0·05) dressing proportion than the other genotypes. Carcass conformation classification (assessed on a five-point scale) was higher (P < 0·001) in lambs finished on the LFC diet (3·0 v. 2·4 (S.E. 0·04)). Conformation classification was higher in lambs produced from Cheviot compared with Blackface ewes (P < 0·05). Within the Blackface cross lambs, BXB and BLXB lambs had a lower conformation classification (P < 0·001) than TXB lambs (2·4, 2·4 and 2·9 (S.E. 0·08) respectively). Within the Cheviot ewes, TXC lambs had a higher (P < 0·001) classification than either CXC or SXC (3·1, 2·7 and 2·7 (S.E. 0·08) respectively). Lambs finished on the LFC diet had a higher fat classification score compared with lambs on the HFC diet (P < 0·001) (3·4 v. 2·8 (S.E. 0·04)). Fat classification was similar across all genotypes. Lambs finished on the LFC diet had a lower ash content in the carcass than lambs finished on a HFC diet (P < 0·01) (44 v. 47 (S.E. 0·8) g/kg). Lamb genotype and dietary forage:concentrate ratio had no significant effect on cooking loss, sarcomere length, Warner–Bratzler shear force and L* values. Ultimate pH (pHU) was not influenced by dietary forage:concentrate ratio, but was significantly (P < 0·01) higher in BXB lambs compared with BLXB, TXB, CXC and TXC lambs. Lambs offered the LFC diet during the finishing period had significantly higher values for a* (P < 0·05), b* (P < 0·001), C* (P < 0·001) and H0 (P < 0·05) than lambs offered a HFC diet. Of these parameters only b* was significantly affected by lamb genotype, with BXB lambs having a lower value (P < 0·05) than the other genotypes.


1988 ◽  
Vol 68 (4) ◽  
pp. 1121-1129 ◽  
Author(s):  
W. N. MASON ◽  
P. M. FLIPOT

Five timothy (Phleum pratense L.) cultivars, Clair, Champ, Milton, Climax and Bounty, were harvested at first flower stage during 2 consecutive years and in the regrowth for 1 yr. The forages were each offered as hay to 15 young rams to evaluate voluntary intake. Five animals were used to determine initial harvest dry matter digestibility. The cultivars varied significantly in voluntary intake at first flower stage. The highest intake (g kg−0.75 d−1) averaged for the years was obtained in the early cultivar Champ (65.9), which was 10% more than that of the medium-late cultivar Climax. The cultivars did not differ significantly in dry matter digestibility. In the regrowth, the relative intakes of the cultivars were essentially reversed from that of the initial harvest. The voluntary intake was substantially higher but the differences among forages were less marked. Climax regrowth voluntary intake was higher (P < 0.05) than all cultivars, except Bounty. A 15% range in digestible dry matter intake was present among cultivars. The ranking of the culivars for digestible dry matter was different than for dry matter yield. Key words: Timothy, Phleum pratense L., voluntary intake, dry matter digestibility


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