CHANGES IN LEVELS OF BLOOD CONSTITUENTS DURING FATTENING OF HEREFORD AND ANGUS COWS

1975 ◽  
Vol 55 (3) ◽  
pp. 403-408
Author(s):  
D. M. BOWDEN ◽  
R. HIRONAKA
Keyword(s):  
Blood Glucose ◽  
Plasma Cholesterol ◽  
Hemoglobin Concentration ◽  
High Energy ◽  
Blood Levels ◽  
Caloric Content ◽  
Mean Corpuscular Hemoglobin ◽  
Marbling Score ◽  
Blood Constituents ◽  
Glucose Levels

Blood samples were taken after 36, 94, and 136 days on feed from 20 Angus and 20 Hereford nonpregnant, nonlactating cows being fattened on two diets of similar caloric content. Carcass measurements averaged 31 mm for backfat and 4.3 for marbling score when the animals were slaughtered soon after the third blood sampling. Blood PCV and hemoglobin levels increased (P < 0.05) from 36 to 94 days on feed but did not change significantly from 94 to 136 days. Blood glucose and mean corpuscular hemoglobin concentration increased (P < 0.05) from 36 to 136 days. Total plasma cholesterol levels increased (P < 0.05) from 36 to 94 days on feed and then decreased (P < 0.05) to 136 days; however, the levels at 136 days remained higher (P < 0.05) than at 36 days. Plasma triglyceride levels tended to increase through the trial, but the changes were not significant. Plasma NEFA levels increased (P < 0.05) from 94 to 136 days. Angus cows had higher (P < 0.05) PCV values and blood glucose levels than Hereford cows only at 136 days. Body weight gains in the period from 94 to 136 days on feed were significantly correlated (P < 0.01) with changes in the same period in blood levels of glucose (r = 0.46), total cholesterol (r = 0.67), and triglycerides (r = 0.49). Results of this study suggest that even after long periods of high energy feeding, the metabolism of fattening cows was still adjusting, as indicated by changes in levels of some blood constituents.

Evaluation of Glucose and Lipid Lowering Activity of Arganimide A in Normal and Streptozotocin-Induced Diabetic Rats

2019 ◽  
Vol 19 (4) ◽  
pp. 503-510 ◽  
Author(s):  
Mohamed Eddouks ◽  
Farid Khallouki ◽  
Robert W. Owen ◽  
Morad Hebi ◽  
Remy Burcelin
Keyword(s):  
Body Weight ◽  
Blood Glucose ◽  
Oral Administration ◽  
Lipid Profile ◽  
Plasma Cholesterol ◽  
Diabetic Rats ◽  
Lipid Lowering ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Lowering Activity

Aims: Arganimide A (4,4-dihydroxy-3,3-imino-di-benzoic acid) is a compound belonging to a family of aminophenolics found in fruit of Argania spinosa. The purpose of this study was to investigate the glucose and lipid lowering activity of Arganimide A (ARG A). Methods: The effect of a single dose and daily oral administration of Arganimide A (ARG A) on blood glucose levels and plasma lipid profile was tested in normal and streptozotocin (STZ) diabetic rats at a dose of 2 mg/kg body weight. Results: Single oral administration of ARG A reduced blood glucose levels from 26.50±0.61 mmol/L to 14.27±0.73 mmol/L (p<0.0001) six hours after administration in STZ diabetic rats. Furthermore, blood glucose levels were decreased from 5.35±0.30 mmol/L to 3.57±0.17 mmol/L (p<0.0001) and from 26.50±0.61 mmol/L to 3.67±0.29 mmol/L (p<0.0001) in normal and STZ diabetic rats, respectively, after seven days of treatment. Moreover, no significant changes in body weight in normal and STZ rats were shown. According to the lipid profile, the plasma triglycerides levels were decreased significantly in diabetic rats after seven days of ARG treatment (p<0.05). Moreover, seven days of ARG A treatment decreased significantly the plasma cholesterol concentrations (p<0.001). Conclusion: ARG A possesses glucose and lipid-lowering activity in diabetic rats and this natural compound may be beneficial in the treatment of diabetes.

scholarly journals Inaccuracy in automated measurement of hematocrit and corpuscular indices in the presence of severe hyperglycemia

Blood ◽  
1981 ◽  
Vol 57 (6) ◽  
pp. 1065-1067 ◽  
Author(s):  
JA Strauchen ◽  
W Alston ◽  
J Anderson ◽  
Z Gustafson ◽  
LF Fajardo
Keyword(s):  
Blood Glucose ◽  
Mean Corpuscular Volume ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Volume ◽  
Automated Measurement ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Corpuscular Hemoglobin ◽  
Hyperosmolar Glucose

Abstract Because we recently observed two patients with severe diabetic hyperglycemia and spuriously elevated electronically determined hematocrit and mean corpuscular volume (MCV), we investigated the effect of hyperglycemia on two popular automated hematology systems, the Coulter S and Ortho ELT-8. Marked hyperglycemia (blood glucose 800-- 2000 mg/dl) caused consistent overestimation of the electronically determined MCV compared to that derived from a simultaneous spun microhematocrit. The resultant overestimation and underestimation, respectively, of the derived values for hematocrit and mean corpuscular hemoglobin concentration may be clinically misleading. The mechanism of MCV elevation in hyperglycemia appears to be swelling of hyperosmolar glucose “loaded” erythrocytes when diluted into “isotonic” counting medium. This effect is readily circumvented by determination of a spun microhematocrit.

Relation between debrisoquine oxidation phenotype and morphological, biological, and pathological variables in a large population

1991 ◽  
Vol 37 (3) ◽  
pp. 327-332 ◽  
Author(s):  
M Vincent-Viry ◽  
J Muller ◽  
B Fournier ◽  
M M Galteau ◽  
G Siest
Keyword(s):  
Large Population ◽  
Hemoglobin Concentration ◽  
Poor Metabolizers ◽  
Mean Corpuscular Hemoglobin ◽  
Extensive Metabolizers ◽  
Mean Cell Volume ◽  
Factors Affecting ◽  
Blood Constituents ◽  
Debrisoquine Oxidation ◽  
Oxidation Phenotype

Abstract Factors affecting biological variations in debrisoquine-oxidation polymorphism were investigated in a population of 3065 unrelated supposedly healthy Caucasian subjects, ages 35 to 50 years. This population, including 1526 men and 1539 women, was used to determine whether the debrisoquine-oxidation phenotype can be related with environmental factors such as alcohol intake, smoking habits or medication; with morphological variables; or with 22 blood constituents and some pathological states. A single dose of 10 mg of debrisoquine sulfate was administered to determine the oxidation phenotype. A metabolic ratio (debrisoquine/4-hydroxydebrisoquine) of 10.0 defined a poor metabolizer [frequency of 8.2% (SD 1.0%)] in this sample. Dose recoveries of debrisoquine excretion (mean and SD) were 8.9% (11.9%) and 45.1% (32.2%) in extensive and poor metabolizers, respectively. The mean (SD) amount of debrisoquine administered that was excreted in urine as 4-hydroxydebrisoquine was 17.4% (17.3%) in extensive metabolizers and 0.5% (0.9%) in poor metabolizers. The main factors differing significantly between poor and extensive metabolizers were mean cell volume, mean corpuscular hemoglobin concentration, albumin, and ponderal index. No other blood constituents (e.g., cholesterol, glucose) differed between poor and extensive metabolizers. The lack of correlation with most of the variables tested is of interest in clinical trials, because our findings indicate that no subgroups will be required, making selection of subjects easier.

scholarly journals Obesitas Sentral terhadap Kadar Gula Darah Postprandial pada Pegawai Laki-Laki Dewasa di Lingkungan Kerja

2019 ◽  
Vol 10 (3) ◽  
pp. 445
Author(s):  
Andini Bakti Putri ◽  
Anita Anita
Keyword(s):  
Blood Glucose ◽  
Adult Male ◽  
Central Obesity ◽  
Postprandial Blood Glucose ◽  
Blood Levels ◽  
Chi Square ◽  
Male Adult ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Chi Square Test

<p>Type 2 diabetes patients as much as 80% are overweight (obese). The obesity rate in Lampung province is 8.7%. The lowest prevalence of central obesity is 2.2% in North Lampung and 35.9% is highest in Metro city. Obesity causes changes in body cells to become resistant to the hormone insulin, so that blood levels increase. The effect of it is that insulin-producing cells work harder and become gradually damaged, these are the reason that causes an increase in the number of diabetics. The purpose of this study to determine the relations of central obesity to postprandial blood glucose levels in adult male employees at Lampung University. This research used a cross-sectional approach. The sample of this research is all male employees of Lampung University with ages of 26-45 years determined by consecutive sampling. 65 respondents like to check postprandial blood glucose levels. The data were analyzed by using the Chi-Square test. Most of the respondents had abnormal postprandial blood glucose levels (67.7%) than respondents who had normal postprandial blood glucose levels (32.3%). Based on bivariate analysis with the Chi-square test, the relation of central obesity and postprandial blood glucose levels in male adult employees in Lampung University with a p-value of 0.001. There is a relationship between central obesity in adult male employees and postprandial blood glucose levels at Lampung University.</p>

scholarly journals Inaccuracy in automated measurement of hematocrit and corpuscular indices in the presence of severe hyperglycemia

Blood ◽  
1981 ◽  
Vol 57 (6) ◽  
pp. 1065-1067
Author(s):  
JA Strauchen ◽  
W Alston ◽  
J Anderson ◽  
Z Gustafson ◽  
LF Fajardo
Keyword(s):  
Blood Glucose ◽  
Mean Corpuscular Volume ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Volume ◽  
Automated Measurement ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Corpuscular Hemoglobin ◽  
Hyperosmolar Glucose

Because we recently observed two patients with severe diabetic hyperglycemia and spuriously elevated electronically determined hematocrit and mean corpuscular volume (MCV), we investigated the effect of hyperglycemia on two popular automated hematology systems, the Coulter S and Ortho ELT-8. Marked hyperglycemia (blood glucose 800-- 2000 mg/dl) caused consistent overestimation of the electronically determined MCV compared to that derived from a simultaneous spun microhematocrit. The resultant overestimation and underestimation, respectively, of the derived values for hematocrit and mean corpuscular hemoglobin concentration may be clinically misleading. The mechanism of MCV elevation in hyperglycemia appears to be swelling of hyperosmolar glucose “loaded” erythrocytes when diluted into “isotonic” counting medium. This effect is readily circumvented by determination of a spun microhematocrit.

scholarly journals Pengaruh Pemberian Puding Susu Buah Naga Merah (Hylocereus Polyrhizus) Terhadap Kadar Glukosa Darah Puasa Pasien Diabetes Mellitus Tipe 2

2019 ◽  
Vol 4 (2) ◽  
pp. 142
Author(s):  
Nunung Setyani ◽  
Ni Ketut Sri Sulendri ◽  
Fifi Lutfiah ◽  
Suhema Suhaema
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Control Group ◽  
Blood Levels ◽  
P Value ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Dragon Fruit ◽  
The Difference ◽  
Hylocereus Polyrhizus

Background: One of the typical signs of diabetes mellitus (DM) is hyperglycemia, which is one medical condition that consists of increasing hormone levels within normal limits. Basic Health Research Results in 2018 DM prevalence in Indonesia increased from 6.9% in 2013 to 8.5% in 2018 (Ministry of Health, 2018). One of the nutritional therapies for the management of diabetes mellitus is fiber consumption. Fruit which contains high fiber, one of which is dragon fruit. Research by Wiardani et al., (2014) provides dragon fruit juice 200 grams of blood glucose levels in DM patients with an average decrease in Prondrial 2 hours Post blood calcium level (2JPP) of 79.1 mg / dL and research by Hidayati (2017) ) by giving red dragon fruit 200 grams of reduction in fasting blood by 19.1 mg / dL.Purpose :To determine the difference in levels of red dragon fruit (hylocereus polyrhizus) against decreasing fasting blood glucose levels of type 2 diabetes patien Method: Research quasy experimental pre post test with control group. Results: The results of the statistical analysis paired with the t-test in the assessment group showed differences in the fasting blood levels of the pretest-posttest with a p value of 0.008 (p <0.05), meaning that it was consistent with contributions related to blood count before and replacement. The results of the independent t-test showed that there was no difference in the difference between fasting blood levels in the advisory group and the control group that discussed the p value of 0.070. (p> 0.05).Conclusion: There is no contribution of giving red dragon fruit milk pudding (Hylocereus polyrhizus) to the reduction of blood glucose levels of type II diabetes mellitus patients.

A note on draught capacity in castrated and entire male buffaloes as reflected in some blood constituents

1978 ◽  
Vol 27 (2) ◽  
pp. 237-240 ◽  
Author(s):  
O. P. Nangia ◽  
R. D. Rana ◽  
Narinder Singh ◽  
A. Ahmad
Keyword(s):  
Lactic Acid ◽  
Blood Glucose ◽  
Pyruvic Acid ◽  
Constant Speed ◽  
Blood Levels ◽  
Buffalo Calves ◽  
Blood Constituents ◽  
Icteric Index ◽  
Response To Exercise ◽  
Entire Male

ABSTRACTCastrated and entire male buffalo calves of about 2 years of age were made to work by pulling a stone roller weighing 80 kg at a constant speed of about 3 km/h on even ‘Kachha’ ground for 3 h. Blood levels of lactic acid and pyruvic acid and the Icteric index increased, whereas blood levels of bicarbonate and proteins decreased in response to exercise. No change was observed in blood glucose or chloride levels. There was no difference in the concentrations of blood constituents of the two groups.

METABOLIC EFFECTS OF UREA ADMINISTRATION ON ACUTE HYPOTHERMIA IN RATS

1960 ◽  
Vol 38 (1) ◽  
pp. 709-714
Author(s):  
John R. Beaton
Keyword(s):  
Lactic Acid ◽  
Blood Glucose ◽  
Intraperitoneal Administration ◽  
Amino Nitrogen ◽  
Inorganic Phosphorus ◽  
Metabolic Effects ◽  
Blood Levels ◽  
Total Acid ◽  
Successful Resuscitation ◽  
Glucose Levels

Acute hypothermia (15 °C rectal temperature) has been induced in fasted rats with and without prior intraperitoneal administration of urea. In the hypothermic animal, not given urea, blood glucose and pH were significantly decreased; blood lactic acid, inorganic phosphorus, and packed cell volume were significantly increased; no alterations occurred in blood levels of pyruvic acid, total acid-soluble phosphorus, urea, nor amino nitrogen. Prior administration of urea prevented significant alterations of blood glucose and lactic acid in the cooled animal. In the non-cooled animal, urea treatment resulted in elevated blood glucose levels. These effects are discussed in relation to the beneficial action of urea in permitting successful resuscitation and survival in a normal condition of rats cooled to rectal temperatures of 0–3 °C.

Cerebral carbohydrate and energy metabolism during hypoglycemia in newborn dogs

1981 ◽  
Vol 240 (3) ◽  
pp. R192-R199 ◽  
Author(s):  
R. C. Vannucci ◽  
E. E. Nardis ◽  
S. J. Vannucci ◽  
P. A. Campbell
Keyword(s):  
Blood Glucose ◽  
Glucose Consumption ◽  
Regular Insulin ◽  
High Energy ◽  
Glycolytic Flux ◽  
Glucose Levels ◽  
Glycolytic Intermediates ◽  
Withdrawal Reflexes ◽  
Lactate Levels ◽  
Blood Glucose Concentrations

The metabolic responses of the perinatal brain to hypoglycemia were studied in newborn dogs. Hypoglycemia, induced by the intravenous injection of regular insulin (0.2-0.3 U/g body wt), resulted in final blood glucose concentrations ranging from 0.1 to 1.5 mmol/l; blood lactate levels were little changed from normoglycemic values. Righting, sucking, and nociceptive withdrawal reflexes were progressively lost during the course of hypoglycemia. Slowing of the electroencephalogram was apparent at or below 1.5 mmol/l blood glucose and advanced to paroxysmal discharges and convulsive activity as glucose approached 0.5 mmol/l. In lightly anesthetized, paralyzed, and artificially ventilated puppies, blood glucose concentrations approximating 1.0 mmol/l were associated with a 91% reduction in cerebral glucose; the concentrations of other glycolytic intermediates (glucose 6-phosphate, fructose 6-phosphate, fructose 1,6-diphosphate, pyruvate, lactate) were unchanged from control. Further declines in blood glucose resulted in cerebral glucose levels below 0.1 mmol/kg as well as in partial depletions of all measured glycolytic intermediates including lactate. These changes reflect reduced cerebral glucose consumption and glycolytic flux. Despite the alterations in carbohydrate metabolism, both lactate/pyruvate ratios and high-energy phosphate reserves (phosphocreatine, ATP, ADP) in brain were well preserved even at the extreme of hypoglycemia. The present data, coupled with previous findings of enhanced lactic acid entry into and consumption by newborn dog brain, suggest that this metabolite serves as an important, if not the predominant, substitute fuel for cerebral oxidative metabolism during perinatal hypoglycemia.

VARIATIONS IN THE BLOOD COMPOSITION OF NON-PREGNANT HEREFORD AND ANGUS HEIFERS FED INDIVIDUALLY IN CONFINEMENT ON TWO LEVELS OF ENERGY INTAKE

1979 ◽  
Vol 59 (4) ◽  
pp. 663-674
Author(s):  
D. M. BOWDEN ◽  
G. C. KOZUB
Keyword(s):  
Energy Intake ◽  
High Energy ◽  
The Other ◽  
Nonesterified Fatty Acid ◽  
Total Serum ◽  
Total Serum Cholesterol ◽  
Blood Constituents ◽  
Glucose Levels ◽  
Dietary Phosphorus ◽  
Angus Heifers

Ten Hereford heifers and 10 Angus heifers were given a high energy diet and equal numbers of Hereford and Angus heifers a low energy diet in individual pens from an average age of 476 day s. After 140 day s, one-half of the heifers of each breed on each energy level were changed to the other level while the other half of the heifers remained on the same level for a further 140 days. Blood samples were taken each 28 days to determine the influence of date of sampling and energy intake on levels of organic and inorganic constituents in the blood. Daily gains averaged 0.2 kg on the low and 0.6 kg on the high energy intake. Levels of all the blood constituents measured differed significantly (P < 0.05) between some of the sampling days. Levels of packed cell volume, whole blood glucose and corrected glucose were highest in January, which was the coldest day of blood sampling, and remained high until April. Serum potassium levels declined over the period of the trial. Total serum cholesterol levels increased (P < 0.01) and plasma nonesterified fatty acid levels decreased (P < 0.05) when energy intakes were increased. Serum phosphorus levels increased (P < 0.05) when dietary phosphorus intakes increased. Angus heifers had higher (P < 0.05) corrected glucose levels in their blood than did Hereford heifers.

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