Effect of Oral Administration of Lactobacillus plantarum HY7714 on Epidermal Hydration in Ultraviolet B-Irradiated Hairless Mice

2014 ◽  
Vol 24 (12) ◽  
pp. 1736-1743 ◽  
Author(s):  
Jehyeon Ra ◽  
Dong Eun Lee ◽  
Sung Hwan Kim ◽  
Ji-Woong Jeong ◽  
Hyung Keun Ku ◽  
...  
Keyword(s):  
Oral Administration ◽  
Lactobacillus Plantarum ◽  
Ultraviolet B ◽  
Hairless Mice

Oral Administration of Lactobacillus plantarum HY7714 Protects Hairless Mouse Against Ultraviolet B-Induced Photoaging

2014 ◽  
Vol 24 (11) ◽  
pp. 1583-1591 ◽  
Author(s):  
Hyun Mee Kim ◽  
Dong Eun Lee ◽  
Soo Dong Park ◽  
Yong-Tae Kim ◽  
Yu Jin Kim ◽  
...  
Keyword(s):  
Oral Administration ◽  
Lactobacillus Plantarum ◽  
Hairless Mouse ◽  
Ultraviolet B

scholarly journals Oral Intake of Collagen Peptide Attenuates Ultraviolet B Irradiation-Induced Skin Dehydration In Vivo by Regulating Hyaluronic Acid Synthesis

2018 ◽  
Vol 19 (11) ◽  
pp. 3551 ◽  
Author(s):  
Min Kang ◽  
Silvia Yumnam ◽  
Sun Kim
Keyword(s):  
Hyaluronic Acid ◽  
Oral Administration ◽  
Protein Expression ◽  
Ultraviolet B ◽  
Skin Hydration ◽  
Skin Barrier Function ◽  
Hairless Mice ◽  
Uvb Irradiation ◽  
Collagen Peptide

Collagen peptide (CP) has beneficial effects on functions of the skin, such as skin barrier function and skin elasticity, in vivo. However, there are few studies investigating the mechanism underlying the potential effects of CP in skin epidermal moisturization after ultraviolet B (UVB) irradiation. In this study, we examined whether orally-administered CP affects the loss of skin hydration induced by UVB irradiation in hairless mice. SKH-1 hairless mice were orally administered CP at two doses (500 and 1000 mg/kg) for nine weeks, and the dorsal skin was exposed to UVB. The potential effects of CP were evaluated by measuring the transepidermal water loss (TEWL), skin hydration, wrinkle formation, and hyaluronic acid expression in the dorsal mice skin. We found that oral administration of CP increased skin hydration and decreased wrinkle formation compared to the UVB-irradiated group. Treatment of CP increased the mRNA and protein expression of hyaluronic acid synthases (HAS-1 and -2) concomitant with an increased hyaluronic acid production in skin tissue. The expression of hyaluronidase (HYAL-1 and 2) mRNA was downregulated in the CP-treated group. In addition, the protein expression of skin-hydrating factors, filaggrin and involucrin, was upregulated via oral administration of CP. In summary, these results show that oral administration of CP increases hyaluronic acid levels, which decreases during UVB photoaging. Therefore, we suggest that CP can be used as a nutricosmetic ingredient with potential effects on UVB-induced skin dehydration and moisture loss in addition to wrinkle formation.

scholarly journals Oral administration of bovine lactoferrin attenuates ultraviolet B-induced skin photodamage in hairless mice

2014 ◽  
Vol 97 (2) ◽  
pp. 651-658 ◽  
Author(s):  
M. Murata ◽  
T. Satoh ◽  
H. Wakabayashi ◽  
K. Yamauchi ◽  
F. Abe ◽  
...  
Keyword(s):  
Oral Administration ◽  
Ultraviolet B ◽  
Bovine Lactoferrin ◽  
Hairless Mice

scholarly journals An Anthocyanin-Enriched Extract from Vaccinium uliginosum Improves Signs of Skin Aging in UVB-Induced Photodamage

Antioxidants ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 844
Author(s):  
Kyungae Jo ◽  
Gi Yeon Bae ◽  
Kyoungwon Cho ◽  
Sung Sun Park ◽  
Hyung Joo Suh ◽  
...  
Keyword(s):  
Oral Administration ◽  
High Performance ◽  
Molecular Mechanisms ◽  
Transepidermal Water Loss ◽  
Ultraviolet B ◽  
Parameter Analysis ◽  
Tissue Inhibitor Of Metalloproteinase ◽  
Biophysical Parameters ◽  
Hairless Mice ◽  
Vaccinium Uliginosum

Accumulating evidence indicates that botanical extracts affect skin biophysical parameters, such as hydration, transepidermal water loss (TEWL), melanin index, erythema index, and wrinkle development. Vaccinium uliginosum extract contains a high level of anthocyanins as antioxidant and is ideal for use in dietary skin care products. Here, we assessed the photoprotective effects of dietary V. uliginosum extract in ultraviolet B (UVB)-irradiated hairless mice. Quantitative analysis of anthocyanin composition in the ethanol-extracted V. uliginosum sample was performed using high-performance liquid chromatography (HPLC). Skin parameter analysis and hematoxylin and eosin (H&E) staining were conducted on skin samples from UVB-irradiated hairless mice to evaluate the effects of V. uliginosum extract on skin conditions. In addition, skin mRNA and protein expression were assessed to characterize the molecular mechanisms underlying the effects of the anthocyanin-enriched extract on skin appearance and condition. Administration of the ethanol-extracted V. uliginosum sample caused significant changes in skin water-holding capacity, TEWL, wrinkle-related parameters, and epidermal thickness in UVB-irradiated hairless mice. In addition, oral administration of V. uliginosum attenuated the gene expression of matrix metalloproteinase (MMP) and increased levels of tissue inhibitor of metalloproteinase (TIMP) and antioxidant-related genes. Further, V. uliginosum administration downregulated inflammatory cytokine levels and UVB-induced phosphorylation of extracellular signaling regulated kinase (ERK), as well as Jun N-terminal kinase (JNK) and p38 protein levels. Oral administration of anthocyanin-enriched V. uliginosum extract can improve the appearance and condition of the skin following UV irradiation.

scholarly journals Effects of Porcine Placenta Extract Ingestion on Ultraviolet B-induced Skin Damage in Hairless Mice

2015 ◽  
Vol 35 (3) ◽  
pp. 413-420 ◽  
Author(s):  
Ki-Bae Hong ◽  
Yooheon Park ◽  
Jae Hwan Kim ◽  
Jin Man Kim ◽  
Hyung Joo Suh
Keyword(s):  
Ultraviolet B ◽  
Skin Damage ◽  
Hairless Mice

scholarly journals Wheat Extract Oil (WEO) Attenuates UVB-Induced Photoaging via Collagen Synthesis in Human Keratinocytes and Hairless Mice

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 300 ◽  
Author(s):  
Dong Ju Son ◽  
Jae Chul Jung ◽  
Yong Min Choi ◽  
Hyeon Yeol Ryu ◽  
Somin Lee ◽  
...  
Keyword(s):  
Oral Administration ◽  
Barrier Function ◽  
Collagen Synthesis ◽  
Skin Barrier ◽  
Human Keratinocytes ◽  
Water Evaporation ◽  
Skin Barrier Function ◽  
Type I ◽  
Skin Damage ◽  
Hairless Mice

The efficacy of wheat extract oil (WEO), standardized to glucosylceramides, for protecting against ultraviolet B (UVB)-induced damage of skin barrier function was assessed using the SHK-1 hairless mouse model and two human skin cell lines, namely, CCD-986sk and HeCaT. The ability of repeated oral administration of 30, 60, and 120 mg of WEO/kg/day for 12 weeks to prevent skin damage of SKH-1 hairless mice induced by UVB irradiation was evaluated. The results demonstrated that UVB-induced water evaporation (transepidermal water loss, TEWL) was significantly decreased by WEO. Similarly, UVB-induced losses in moisture and skin elasticity were improved by WEO supplementation. WEO attenuated the tissue procollagen type I, hyaluronic acid (HA), and ceramide reductions induced by UVB treatment as well. Collagen concentrations in skin tissue were increased in the WEO-treated mice, while UVB-induced epidermal thickening was reduced. In vitro studies using HeCaT human keratinocytes confirmed increased HA and collagen synthesis in response to WEO treatment. This may occur via WEO suppression of matrix metalloproteinase-1 (MMP-1), since its induction by UVB treatment was diminished in treated CCD-986sk cells. Oral administration of WEO improves skin barrier function in UVB-irradiated mice by attenuating damage typically observed in photoaging. This research further clarifies the clinical benefits previously observed by dietary WEO consumption.

scholarly journals Oral Administration of Glycine and Leucine Dipeptides Improves Skin Hydration and Elasticity in UVB-Irradiated Hairless Mice

2017 ◽  
Vol 25 (5) ◽  
pp. 528-534 ◽  
Author(s):  
Jong Il Park ◽  
Ji Eun Lee ◽  
Hyun Jun Shin ◽  
Soonran Song ◽  
Won Kyung Lee ◽  
...  
Keyword(s):  
Oral Administration ◽  
Skin Hydration ◽  
Hairless Mice

scholarly journals Chemopreventive Effects of Sarcophine-diol on Ultraviolet B-induced Skin Tumor Development in SKH-1 Hairless Mice

Marine Drugs ◽  
2009 ◽  
Vol 7 (2) ◽  
pp. 153-165 ◽  
Author(s):  
Xiaoying Zhang ◽  
Ajay Bommareddy ◽  
Wei Chen ◽  
Michael Hildreth ◽  
Radhey Kaushik ◽  
...  
Keyword(s):  
Tumor Development ◽  
Ultraviolet B ◽  
Skin Tumor ◽  
Hairless Mice
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