scholarly journals A STUDY OF BODY CAVITY EFFUSIONS AND ITS DIAGNOSTIC UTILITY OF CELL BLOCK AS AN ADJUNCT TO CONVENTIONAL CYTOLOGICAL SMEARS

2020 ◽  
pp. 10-11
Author(s):  
Ankan Nandi ◽  
Debarshi Jana

Background: The cell block technique is one of the oldest method for evaluation of body cavity fluids and it increases the sensitivity of the diagnosis in comparison to conventional smear study. The main advantage of cell block technique is preservation of tissue architecture and obtaining multiple sections for special stains. Aim: To assess the utility of cell block method in increasing the sensitivity of cytological diagnosis of body cavity effusions as an adjunct to conventional smear method. Material and methods: It was institution based cross sectional observational study. All patients presenting with effusion and those who was give consent for participating in the study was included in this study. The study was conducted in Dept. Of Pathology, Nandigram Superspeciality Hospital. 100 cases fulfilling the predetermined inclusion and exclusion criteria was taken during the study period. Result: Association of Cellularity vs cell block was statistically significant (p<0.0001). Association of Architectural Pattern vs cell block was not statistically significant (p=0.7883). Association of cytological smears vs cell block was statistically significant (p=<0.0001). Conclusion: Cell block technique is superior to conventional smear technique, especially for malignant effusions.

2019 ◽  
Vol 64 (3) ◽  
pp. 265-269 ◽  
Author(s):  
Heli Hakso-Mäkinen ◽  
Ivana Kholová

Objective: Cell blocks (CBs) are used to complement cytological diagnosis and for ancillary testing. Dissatisfaction with the cellular yield of the CB is widely recognized. Various techniques have been developed to increase the diagnostic utility of CBs. Study Design: We invented a new CB technique to increase cellular yield and diagnostic accuracy suitable especially for mucous and/or bloody cytological samples. Results: The new CB technique is described in detail with illustrations and cases, where it increased the cellular yield and diagnostic accuracy. CBs prepared by this method are suitable also for ancillary techniques, namely immunocytochemistry. Conclusions: The newly described method showed a better cellular yield in mucous and/or bloody cytological specimens.


2014 ◽  
Vol 1 (9) ◽  
pp. 1240-1245
Author(s):  
Gayathri M N ◽  
Kunal Puri ◽  
Satish M K ◽  
Ravikumar T ◽  
Bharathi M

2019 ◽  
Vol 5 (3) ◽  
pp. 167
Author(s):  
Mardhiyyah Nurul Hasanah ◽  
Dwita Aryadina Rachmawati ◽  
Erfan Efendi

Abstract The first three years of age is an important period for the development of children’s languange. Early stimulation as a parent especially mother to promote children’s development needs to be done. Before doing stimulation, the mothers need sufficient knowledge about development stimulation so mothers can do stimulation properly to their children. The aim of this study is to analyze the correlation between the mother’s knowledge about language stimulation and language development of toddlers in Lengkong , Mumbulsari, Jember. An analitic observational study with cross sectional study design which the subjects were 70 mother who have toddlers at Lengkong, Mumbulsari, Jember who met inclusion and exclusion criteria. The result of spearman correlation test between mother’s knowledge about language stimulation and language development of children aged 1-3 years is p=0,000 (p<0.005) which mean there is significant correlation between the mother’s knowledge about language stimulation and language development of children aged 1-3 years in Lengkong , Mumbulsari, Jember.   Keywords: knowledge, stimulation, language development.


2012 ◽  
Vol 29 (1) ◽  
pp. 11 ◽  
Author(s):  
Udasimath Shivakumarswamy ◽  
MaheshH Karigowdar ◽  
SurekhaU Arakeri ◽  
BR Yelikar

2019 ◽  
Vol 6 (1) ◽  
pp. A18-23
Author(s):  
Falguni J Goswami ◽  
H P Srilakshmi ◽  
Roopam K Gidwani ◽  
Ragini Patel ◽  
Nirali V Shah ◽  
...  

2021 ◽  
Vol 7 (1) ◽  
pp. 9-16
Author(s):  
Dr. Rajesh h. Chandan ◽  
◽  
Dr. Sumana Pawar ◽  
Dr Purushotham Redd ◽  
◽  
...  

Background: Aspiration of serous cavities is a simple and relatively non-invasive technique toachieve diagnosis. Cytological evaluation of body cavity fluid is diagnostically challenging. Especiallyin malignant effusions, helps in staging, prognosis and management of the patients. Aims: Toassess the utility and sensitivity of cell block method over conventional smear technique incytodiagnosis of the serous effusions. And to assess the utility and sensitivity of cytologicalevaluation of body fluids with biochemical and clinical correlation. Methods: A total of 150 fluidspecimens were examined for conventional cytological smear (CS) and cell block method (CB). Outof 150 fluids, 96 were pleural fluid, 48 were ascitic fluid, 04 fluid from pouch of Douglas and 01 wasfrom synovial fluid. Results: In this study, the utility of the CB method in the cytodiagnosis ofmalignant effusions was found to be highly significant as compared to the CS method. The additionalyield of malignancy was 12% more as was obtained by the CB method. Conclusion: For the finalcytodiagnosis of body fluid, there is statistically significant difference between the two techniques. Inother words, CB is superior to CS method. It gives more information about the architecturalarrangement and the likely source of primary. More important is that diagnostic material in cellblocks is available for special studies for Immunohistochemistry which can further supplement ourknowledge about the primary source of metastasis.


2021 ◽  
Vol 9 (3) ◽  
pp. 185-192
Author(s):  
Dr. Rama Saha ◽  
◽  
Dr. Samaresh Sardar ◽  
Dr. Smritiparna Das ◽  
◽  
...  

Introduction: Lung cancer is the most common primary tumor associated with malignant pleuraleffusion (MPE). In this study, we aim to use cell remnants for cell block preparation after performingliquid-based cytology (LBC) of effusion fluid. Immunohistochemistry was helpful to evaluate thosecases having diagnostic dilemmas in LBC and cell block. Method: It was a cross-sectional,prospective, single institution-based study, conducted in the department of Pathology incollaboration with the Department of Respiratory Medicine IPGMER & SSKM Hospital, from January2018 to June 2019 in the institution. Result: Most of the study population were in between the agegroup of 51 to 60 years with male predominance and with fever and cough being the predominantsymptoms. Liquid-based cytology was positive for malignancy in 58% of cases and suspicious ofmalignancy in 22% of cases of malignant pleural effusion and it had 95.35% sensitivity, 58.82%specificity in diagnosing malignant pleural effusion.LBC was done followed by cell block preparationsare studied further by Immunohistochemistry. Discussion: Morphological features were betteridentified by the cell block method when compared to LBC. Multiple sections can be obtained forspecial stain or IHC study which bridges the gap between cytology and histology.


2018 ◽  
Vol 29 (2) ◽  
pp. 57-61
Author(s):  
SM Afzal Uddin ◽  
MK Rahman ◽  
Khan MMR ◽  
M Moksedur Rahman ◽  
MN Islam ◽  
...  

Background: Bronchial asthma isone of the major health problems and causes of chronic morbidity and mortality in Bangladesh as well as worldwide. ECG was performed to observe changes among the patients of bronchial asthma.Objectives: To observe ECG changes among the patients ofbronchial Asthma.Methods: It was a cross-sectional observational study carried out in the Department of Medicine, Rajshahi Medical College Hospital, Rajshahi from July, 2010 to June, 2012. According to inclusion and exclusion criteria 73 people having bronchial asthma were selected. Thorough history, physical examination and spirometric along with ECG assessment were done.Results: In case of bronchial asthma, 03(4.11%) cases showed ECG changes and 70 (95.89%) cases showed normal ECG.Conclusion: In this study, ECG changes were 4.11% in bronchial asthma patients.TAJ 2016; 29(2): 57-61


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