scholarly journals Hydrazine-Selective Fluorescent Turn-On Probe Based on Ortho-Methoxy-Methyl-Ether (o-MOM) Assisted Retro-aza-Henry Type Reaction

Sensors ◽  
2019 ◽  
Vol 19 (20) ◽  
pp. 4525 ◽  
Author(s):  
Jung ◽  
Park ◽  
Kang ◽  
Kim
Keyword(s):  
Fluorescent Probe ◽  
Methyl Ether ◽  
High Selectivity ◽  
Soil Analysis ◽  
Paper Strip ◽  
Molecular Rotor ◽  
Industrial Chemicals ◽  
Potential Health ◽  
Type Reaction ◽  
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Hydrazine (N2H4) is one of the most widely used industrial chemicals that can be utilized as a precursor of pesticides, pharmaceutics, and rocket propellant. Due to its biological and environmental toxicity with potential health risks, various sensing tools have been developed. Among them, fluorescence-based molecular sensing systems have been highlighted due to its simple-operation, high selectivity and sensitivity, and biocompatibility. In our recent report, we disclosed a ratiometric type fluorescent probe, called HyP-1, for the detection of hydrazine, which is based on ortho-methoxy-methyl-ether (o-MOM) moiety assisted hydrazone-formation of the donor (D)-acceptor (A) type naphthaldehyde backbone. As our follow-up research, we disclose a turn-on type fluorescent probe, named HyP-2, as the next-generation hydrazine probe. The sensing rational of HyP-2 is based on the o-MOM assisted retro-aza-Henry type reaction. The dicyanovinyl moiety, commonly known as a molecular rotor, causes significant emission quenching of a fluorescent platform in aqueous media, and its cleavage with hydrazone-formation, which induces a significant fluorescence enhancement. The high selectivity and sensitivity of HyP-2 shows practical explicabilities, including real-time paper strip assay, vapor test, soil analysis, and real water assay. We believe its successful demonstrations suggest further applications into a wide variety of fields.

Colorimetric and Fluorescent Probe for Hypochlorite with High Selectivity

2013 ◽  
Vol 295-298 ◽  
pp. 475-478 ◽  
Author(s):  
Zhi Xiang Han ◽  
Ming Hui Du ◽  
Guo Xi Liang ◽  
Xiang Yang Wu
Keyword(s):  
Reactive Oxygen Species ◽  
Aqueous Solution ◽  
Detection Limit ◽  
Fluorescent Probe ◽  
Rhodamine B ◽  
High Selectivity ◽  
Reactive Oxygen ◽  
Living Cells ◽  
Oxygen Species ◽  
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Rhodamine B thiohydrazide (RBS) was firstly employed as turn-on fluorescent probe for hypochlorite in aqueous solution and living cells. It exhibits a stable response to hypochlorite from 1.0×10-6to 1.0×10-5M with a detection limit of 3.3×10-7M. The response of this probe to hypochlorite is fast and highly selective compared with other reactive oxygen species (such as.OH,1O2, H2O2) and other common anions (such as X-, ClO2-, ClO4-, NO3-, NO2-, OH-, Ac-, CO32-, SO42-).

Rhodamine-based “turn-on” fluorescent probe with high selectivity for Fe2+ imaging in living cells

2013 ◽  
Vol 439 (4) ◽  
pp. 459-463 ◽  
Author(s):  
Gui-Ge Hou ◽  
Chun-Hua Wang ◽  
Ju-Feng Sun ◽  
Mei-Zi Yang ◽  
Dong Lin ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
High Selectivity ◽  
Living Cells ◽  
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scholarly journals A Turn-On Fluorescent Probe for Sensitive Detection of Cysteine in a Fully Aqueous Environment and in Living Cells

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Xiaohua Ma ◽  
Guoguang Wu ◽  
Yuehua Zhao ◽  
Zibo Yuan ◽  
Yu Zhang ◽  
...  
Keyword(s):  
Detection Limit ◽  
Fluorescent Probe ◽  
High Selectivity ◽  
Coumarin Derivative ◽  
Living Cells ◽  
Sensitive Detection ◽  
Aqueous Environment ◽  
Test Probe ◽  
Aqueous Buffer ◽  
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We reported here a turn-on fluorescent probe (1) for the detection of cysteine (Cys) by incorporating the recognition unit of 2,4-dinitrobenzenesulfonyl ester (DNBS) to a coumarin derivative. The structure of the obtained probe was confirmed by NMR and HRMS techniques. The probe shows a remarkable fluorescence off-on response (∼52-fold) by the reaction with Cys in 100% aqueous buffer. The sensing mechanism was verified by the HPLC test. Probe 1 also displays high selectivity towards Cys. The detection limit was calculated to be 23 nM. Moreover, cellular experiments demonstrated that the probe is highly biocompatible and can be used for monitoring intracellular Cys.

“Turn-On” Fluorescent Probe for Mercury(II): High Selectivity and Sensitivity and New Design Approach by the Adjustment of the π-Bridge

2015 ◽  
Vol 7 (21) ◽  
pp. 11369-11376 ◽  
Author(s):  
Jun Ding ◽  
Huiyang Li ◽  
Can Wang ◽  
Jie Yang ◽  
Yujun Xie ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
High Selectivity ◽  
Design Approach ◽  
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Novel Nopinone-Based Turn-on Fluorescent Probe for Hydrazine in Living Cells with High Selectivity

2019 ◽  
Vol 58 (51) ◽  
pp. 22754-22762 ◽  
Author(s):  
Mingxin Li ◽  
Jinfa He ◽  
Zhonglong Wang ◽  
Qian Jiang ◽  
Haiyan Yang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
High Selectivity ◽  
Living Cells ◽  
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A fluorescent probe for the specific detection of cysteine in human serum samples

2019 ◽  
Vol 11 (26) ◽  
pp. 3280-3285 ◽  
Author(s):  
Zhen Huang ◽  
Cuiyan Wu ◽  
Yaqian Li ◽  
Zile Zhou ◽  
Ruihua Xie ◽  
...  
Keyword(s):  
Human Serum ◽  
Fluorescent Probe ◽  
High Selectivity ◽  
Color Change ◽  
Eye Detection ◽  
Specific Detection ◽  
Serum Samples ◽  
Naked Eye ◽  
Turn On ◽  
Naked Eye Detection

A turn-on fluorescent probe for cysteine with high selectivity was designed and synthetized. The probe can be used for “naked-eye” detection of Cys with an obvious color change from yellow to colorless. The probe could be applied for Cys detection in real human serum.

scholarly journals A new 3-hydroxyphthalimide-based turn-on fluorescent probe for Hg2+ detection in aqueous solution

2020 ◽  
Vol 44 (5-6) ◽  
pp. 349-353
Author(s):  
Xue-Tao Pan ◽  
Qiao Li ◽  
Yuan-Yuan Xu ◽  
Sheng-Li Hu
Keyword(s):  
Aqueous Solution ◽  
Excited State ◽  
Detection Limit ◽  
Fluorescent Probe ◽  
High Selectivity ◽  
Intramolecular Proton Transfer ◽  
Recognition Mechanism ◽  
Turn On ◽  
Transfer Mechanisms ◽  
Analytical Detection

A new 3-hydroxyphthalimide-based turn-on fluorescent probe is designed and synthesized. This probe can be used to determine the presence of Hg2+ ions by fluorescence spectroscope with high selectivity over other metal ions in aqueous solution. The analytical detection limit for Hg2+ is as low as 6.5 × 10−7 M. The recognition mechanism is attributed to Hg2+-promoted carbonothioate group cleavage and a subsequent excited-state intramolecular proton transfer mechanisms.

A rhodamine based “turn-on” fluorescent probe for Pb(ii) and live cell imaging

RSC Advances ◽  
2016 ◽  
Vol 6 (1) ◽  
pp. 656-660 ◽  
Author(s):  
Omprakash Sunnapu ◽  
Niranjan G. Kotla ◽  
Balaji Maddiboyina ◽  
Subramanian Singaravadivel ◽  
Gandhi Sivaraman
Keyword(s):  
Fluorescent Probe ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
High Selectivity ◽  
Aqueous Media ◽  
Live Cell ◽  
Fluorescent Chemosensor ◽  
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A novel “turn-on” fluorescent chemosensor RDP-1 based on rhodamine tri methoxy benzaldehyde conjugate was synthesized, which showed high selectivity and sensitivity towards recognition of Pb2+ in aqueous media.

A flavone-based turn-on fluorescent probe for intracellular cysteine/homocysteine sensing with high selectivity

Talanta ◽  
2016 ◽  
Vol 146 ◽  
pp. 41-48 ◽  
Author(s):  
Jian Zhang ◽  
Yanlin Lv ◽  
Wei Zhang ◽  
Hui Ding ◽  
Rongji Liu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
High Selectivity ◽  
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