scholarly journals Pengaruh Pemberian Jus Sirsak (Annona Muricata Linn) Terhadap Kadar Asam Urat Pada Lansia Dengan Gout

2019 ◽  
Vol 10 (2) ◽  
pp. 634-645
Author(s):  
Fakhrudin Nasrul Sani ◽  
Annisa Cindy Nurul Afni

Latar belakang: gout (pirai) merupakan kelainan metabolisme purin bawaan yang ditandai dengan penimbunan kristal asam urat di sendi. Hal ini menimbulkan arthritis gout akut.Penatalaksanaan secara non farmakologi salah satunya dengan pengobatan tradisional yaitu dengan pemberian jus sirsak. Asamuratsekitar80-85 %diproduksiolehtubuh, sedangkan sisanyaberasaldarimakanan.Kadarasamuratnormalwanitadewasa2,5-5,7 mg.dlpria dewasa 3,4-7,0 mg/ dl dan anak - anak 2,8-4,0 mg/dl.Tujuan: menganalisis pengaruh pemberian jus sirsak terhadap kadar asam urat pada lansia dengan gout. Manfaat Penelitian: meningkatkan ilmu pengetahuan tentang manfaat pemberian jus sirsak (Annona muricata linn.)untuk mengurangi kadar asam urat pada lansia dengan asam urat.Metode penelitian:penelitian ini menggunakan desain penelitian pre eksperimen dengan pre and post test without control yaitu pengaruh pemberian jus sirsak terhadap penurunan  kadar asam urat pada lansia yang menderita gout. Pengambilan data dilakukan dua kali pada saat sebelum perlakuan dan sesudah perlakuan. Pemberian jus sirsak sehari sekali selama 7 hari.Hasil: hasil analisis uji statistik wilcoxon menunjukkan bahwa ada pengaruh pemberian jus sirsak (Annona muricata linn.)terhadap kadar asam urat sebelum dan sesudah pemberian jus sirsak (Annona muricata linn.)dengan nilai p = 0,000 (p 0,05).Kesimpulan: Berdasarkan hasil tersebut, jus sirsak (Annona muricata linn.) berpengaruhterhadap penurunan kadar asam urat pada lansia.Kata Kunci: Gout, jus sirsak, penurunan kadar asam urat Background: gout (gout) is an inherited purine metabolism disorder characterized by accumulation of uric acid crystals in the joints. This causes acute gouty arthritis. One of the non-pharmacological treatments is traditional medicine, which is soursop juice. About 80-85% of the acid is produced by the body, while the remaining is derived from food. Normal normal adult women 2.5-5.7 mg. Adult men 3.4-7.0 mg / dl and children 2.8-4.0 mg / dl.Objective: to analyze the effect of soursop juice on uric acid levels in the elderly with gout.Benefits of research: increasing knowledge about the benefits of soursop juice (Annona muricata linn.) To reduce levels of uric acid in the elderly with gout.Research methods: this study used a pre-experimental research design with pre and post test without control, namely the effect of giving soursop juice on decreasing uric acid levels in the elderly suffering from gout. Data was collected twice before and after treatment. Giving soursop juice once a day for 7 days.Results: the results of the Wilcoxon statistical test analysis showed that there was an effect of soursop juice (Annona muricata linn.) On uric acid levels before and after administration of soursop juice (Annona muricata linn.) With a value of p = 0,000 (p 0.05).Conclusion: Based on these results, soursop juice (Annona muricata linn.) Affects the decrease in uric acid levels in the elderly.Keywords: Gout, soursop juice, decreased uric acid levels

2019 ◽  
Vol 8 (2) ◽  
pp. 25-32
Author(s):  
Nicky Danur Jayanti

Headache is a diffuse pain in various parts of the head which varies in its intensity, and the duration of which is a neurological complaint during pregnancy, to reduce headaches by providing provision of drug therapy from aroma therapy, relaxation massage, hot and cold compresses. A relaxing massage is given to ease the discomfort, maintain the overall function of the body and provide emotional support. The study aimed to find out if there is an effect of a relaxation massage in decreasing headaches in pregnant women trimester I.The research method used was a comparative study using a pre-test and post-test group design. The samples used were 15 pregnant women who fit the inclusion criteria and population as many as 19 respondents. The sampling technique used was purposive sampling. Analysis of the results of research was using the Wilcoxon test analysis. Most of the first trimester pregnant women have headaches prior to  the relaxation massage were 10 respondents (66.7%), relaxation massage after having a mild headache were 11 respondents (73.3%). Based on the analysis of Wilcoxon test obtained value ρ = 0.002, thus it is said that Ha is accepted because ρ <0.05 means that there is  an effect of the level of head pain in the first trimester pregnant women before and after a relaxing massage treatment. It is advised to pregnant women, to add motivation to deal with headaches naturally.


2020 ◽  
Vol 7 (1) ◽  
pp. 15-28
Author(s):  
Cut Rahmiati ◽  
Tjut Irma Zurijah

Hypertension is a condition that is often experienced by the elderly. By increasing age resulting in increased blood pressure, the arterial wall in the elderly will experience thickening which results in the accumulation of collagen in the muscle layer. So that the blood vessels will gradually narrow and become stiff . To avoid or reduce the risk of collagen and atherosclerosis accumulation which is one of the causes of hypertension, regular exercise is needed. Elderly gymnastics is a series of regular and directed and planned tones of movement that are followed by the elderly in the form of physical exercises that affect the physical abilities of the elderly which will help the body stay fit and stay fresh. It keeps bones strong and helps eliminate free radicals wandering in the body and can flex blood vessels. This research is a kind of quasi-experimental research with a pre and post test without control design. This research was conducted in Darussalam, Aceh Besar. Blood pressure is measured using a sphygmomanometer, a statistical test used by Non-parametric. To see blood pressure before and after elderly exercise using the t-test. After doing elderly gymnastics for six times in 2 weeks, there are differences in the value of blood pressure in the elderly before and after elderly gymnastics with a p-value of 0.000. Thus, it is expected that elderly gymnastics can be used as an alternative nursing action in handling hypertension, especially in the elderly. Abstrak Hipertensi merupakan suatau keadaan yang sering dialami oleh lansia, dengan bertambahnya umur mengakibatkan tekanan darah meningkat, karena dinding arteri pada usia lanjut (lansia) akan mengalami penebalan yang mengakibatkan penumpukan zat kolagen pada lapisan otot, sehingga pembuluh darah akan berangsur-angsur menyempit dan menjadi kaku. Untuk menghindari atau menurunkan resiko penumpukan zat kolagen dan aterosklerosis yang merupakan salah satu penyebab hipertensi, maka diperlukan olahraga yang teratur. Senam lansia merupakan serangkaian gerak nada yang teratur dan terarah serta terencana yang diikuti oleh orang lanjut usia dalam bentuk latihan fisik yang berpengaruh terhadap kemampuan fisik lansia, yang akan membantu tubuh agar tetap bugar dan tetap segar karena melatih tulang tetap kuat dan membantu menghilangkan radikal bebas yang berkeliaran dalam tubuh  serta dapat melenturkan pembuluh darah. Penelitian ini merupakan jenis penelitian eksperimen semu (quasi experiment) dengan rancangan pre and post test without control. Penelitian ini dilakukan di Kecamatan Darussalam Kabupaten Aceh Besar terhadap lansia yang mengalami hipertensi. Tekanan darah di ukur dengan menggunakan spigmomanometer, uji statistik yang digunakan Non-parametrik. Untuk melihat tekanan darah sebelum dan sesudah senam lansia menggunakan Uji t-test. Setelah dilakukan senam lansia selama enam (6) kali dalam waktu 2 (dua) minggu pada lansia yang mengalami hipertensi, secara umum terdapat perbedaan tekanan darah pada lansia sebelum dan sesudah senam lansia dengan p-value 0,000, dengan demikian diharapkan senam lansia ini dapat dijadikan sebagai salah satu alternatif tindakan keperawatan dalam penanganan hipertensi terutama pada lansia. Kata Kunci : Hipertensi, Lansia, Senam Lansia


2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Hubert I. Tatara ◽  
Herlina I. S. Wungouw ◽  
Hedison Polii

Abstract: The increase of life expectancy contributes to complex impact on diseases suffered by the elderly. Although it is yet to be considered as a risk factor, data suggests that uric acid is one of the risk factors of cardiovascular disease. Exercise is an effort which prevents the increase of uric acid levels. 'Senam Lansia' (Elderly Aerobics) is a light, simple & easy to apply to the elderly. This study has purposed to know about elderly aerobics effects on uric acid levels in patients with hypertension. This study is a one group pre-post test, that was conducted as a field at BPLU Senja Cerah. Elderly aerobics has been doing 3 times in a week for 3 weeks in 30 subjects. The result shows a significant decrease of uric acid levels before and after the exercise, with an average difference of 1,56 mg/dl. The confidence interval value for lower is 0,84 & 2,28 for upper. Based on the result of statistic test, (p) value which is the signification value is 0,00 smaller than the value of alpha (a = 0,05). This study proves that elderly aerobics contributes significantly in the levels of uric acid in patients with hypertension. Keywords: elderly, elderly aerobics, hypertension, uric acid     Abstrak: Usia harapan hidup yang semakin meningkat, membawa dampak semakin kompleks dalam hal penyakit yang bisa diderita oleh orang lanjut usia. Meskipun belum dianggap sebagai faktor resiko, namun data yang ada menunjukkan asam urat merupakan salah satu faktor resiko penyakit kardiovaskular. Salah satu pencegahan dari meningkatnya kadar asam urat yakni dengan berolahraga. Senam lansia adalah olahraga ringan, mudah dilakukan dan tidak memberatkan untuk diterapkan pada lansia. Penelitian ini bertujuan untuk mengetahui pengaruh senam bugar lansia terhadap kadar asam urat penderita hipertensi. Penelitian bersifat eksperimental lapangan dengan rancangan one group pre-post test yang dilakukan pada 30 penderita hipertensi di BPLU Senja Cerah. Dilakukan senam bugar lansia 3 kali seminggu dengan lama latihan selama 3 minggu. Kadar asam urat sebelum dan sesudah senam diukur, dan dianalisa. Hasil yang didapat, terjadi penurunan bermakna kadar asam urat antara sebelum dan sesudah senam bugar lansia dengan selisih rata-rata sebesar 1,56 mg/dl. Nilai confidence interval, yaitu 0,84 untuk lower dan 2,28 untuk upper. Nilai signifikasi (p) dari hasil uji statistik yaitu 0,00 lebih kecil dari nilai alpha (α = 0,05). Penelitian ini membuktikan adanya pengaruh yang signifikan senam bugar lansia terhadap kadar asam urat penderita hipertensi. Kata Kunci: asam urat, hipertensi, lansia, senam bugar lansia


2021 ◽  
Vol 17 (10) ◽  
pp. 2071-2084
Author(s):  
Tianjiao Han ◽  
Meiying Wang ◽  
Wenchao Li ◽  
Mingxing An ◽  
Hongzheng Fu

Uric acid is the final product of purine metabolism, and excessive serum uric acid can cause gouty arthritis and uric acid nephropathy. Therefore, lowering the uric acid level and alleviating inflammation in the body are the key points to treating these diseases. A stable nanosuspension of peptide BmK9 was prepared by the precipitation-ultrasonication method. By combining uricase on the surface of a positively charged carrier, a complex consisting of neutral rod-shaped BmK9 and uricase nanoparticles (Nplex) was formed to achieve the delivery of BmK9 and uricase, respectively. The formulation of Nplex has a diameter of 180 nm and drug loading up to 200%, which releases BmK9 and uricase slowly and steadily in drug release tests in vitro. There was significantly improved pharmacokinetic behavior of the two drugs because Nplex prolonged the half-life and increased tissue accumulation. Histological assessments showed that the dual drug Nplex can reduce the inflammation response in acute gouty arthritis and chronic uric acid nephropathy in vivo. In the macrophage system, there was lower toxicity and increased beneficial effect on inflammation with Nplex than free BmK9 or uricase. Collectively, this novel formulation provides a dual drug delivery system that can treat gouty arthritis and uric acid nephropathy.


2019 ◽  
Vol 1 (1) ◽  
pp. 1
Author(s):  
Ajeng Fitria ◽  
Leonardo Lubis ◽  
Ambrosius Purba

The increasing number of elderly and elderly life expectancy is a challenge for health workers. Decreased cardiac endurance, muscle strength and increased incidence of inflammation will occur in the elderly as we get older. health cardio exercises series-I is an aerobic exercise that has moderate intensity and is carried out for 30 minutes, research is needed to analyze the effect on cardiac endurance, muscle strength and decrease plasma TNF-? levels in the elderly. Research design with experimental method, pre-test and post-test design approach. The study was conducted for 4 weeks on 25 samples which were divided into 3 groups of frequency of health cardio exercises series-I to measure endurance of the heart. A 6-minute road test and muscle strength were used for hand grip strength dynamometer, test back and leg dynamometer. Measurement of plasma TNF-? levels is carried out using the Elisa method. The data was then analyzed using paired t-test to see differences before and after health cardio exercises series-I. The results showed health cardio exercises series-I performed 3x / mg can increase the heart's endurance compared to the frequency of 4x / mg and 5x / mg (-16.11 vs 15.62 vs -47.62 meters). health cardio exercises series-I frequency of 3x / mg and 4x / mg can increase back muscle strength (p-value = 0.019, p <0.05) and the frequency of 5x / mg can increase the strength of attractive shoulder muscles. (p-value = 0.033, p <0.05). Health cardio exercises series-I performed 3x / mg, 4x / mg and 5x / mg did not have a significant effect on plasma TNF-? protein expression in the elderly (0.506 vs 0.856 vs. 0.382, p <0.05). It is suggested that the elderly can do I-1 series heart exercise with a frequency of 3x / mg to increase the heart's lung endurance and back muscle strength, a health cardio exercises series-I 4x / mg series to increase muscle strength of the back back, a series of health cardio exercises series-I frequency of 5x / mg to increase attractive shoulder muscle strength.


2019 ◽  
Vol 26 (1) ◽  
pp. 26-34
Author(s):  
Dian Dwiana ◽  
Santoso Ujang Effendi ◽  
Vusva Vaudyah

Uric acid is the end product or a waste product resulting from the metabolism/ breakdown of purines .. The purpose of this study was to determine the effectiveness of Soursop fruit juice therapy to decrease uric acid levels in the Elderly Social Institution Tresna Werdha Pagar Dewa Bengkulu year 2018. The design of this Penenlitian pre- experimental. The population in this study who had the Uric Acid in Elderly Social Institution Tresna Pagar Dewa Bengkulu which amount 17 people. The sampling technique used Total sampling technique. Collecting data in this study is the observation uric acid levels before and after therapy soursop juice for 2 minggu..Hasil research showed: (1) there are 17 people (100%) with high levels of uric acid 6 mg / dl; (2) there are 13 people (76.5%) had decreased levels of uric acid, and 4 (23, 5%) who did not experience decreased levels of uric acid; (3) No effect Soursop fruit juice therapy to decrease uric acid levels in the Elderly Social Institution Tresna Werdha Pagar Dewa Bengkulu. Keywords: elderly, uric acid, soursop juice


2020 ◽  
Vol 1 (1) ◽  
pp. 13-16
Author(s):  
Tavip Indrayana ◽  
Warijan Warijan ◽  
Joni Siswanto

ABSTRACTBackground : Joint flexibility decreases in old age due to a degenerative process resulting in changes in joints, connective tissue and cartilage in the elderly. Decreasing flexibility is also due to reduced elasticity of muscle fibers, where connective tissue in muscle fibers increases (Mariyam, 2008).Objective : The aim of this study was to analyze the effect of active exercise (ROM) on the lower extremities on increasing the flexibility of the knee joint in the elderlyMethods : This study using a quasi-experimental approach with One group pre-test and post-test design. The sampling technique uses the Slovin method of 42 people, obtained a sample of 25 elderly. Exercise is done twice a day for 8 days. Measurements were made on day 1, day 4 and day 8 of the study using a Goniometer measuring instrument..Result : The results of measurement I average of the right knee joint 117.52o, measurement II = 122.24, measurement III = 126, 36o. From the analysis with Paired simple t-Test between the measurements I and II, it was found that the different test measurements I and II t count value was equal to -1.908 with 0.068. Because sig 0.05, it can be concluded that Ho is accepted, meaning that the average angle of ROM before and after training is the same (not different). In the different test measurements II and III the value of t count is equal to -2.152 with sig 0.042.Conclusion : Because sig 0.05, it can be concluded that Ho is rejected, meaning that there is a difference in ROM angle after training between days 4 to 8 with the first day to day 4. Thus it can be stated that active ROM exercises affect the angle of ROM of the knee joint elderly after exercise ROM between day 4 to day 8. Keywords: active ROM exercise, flexibility of knee joint, elderly.


2018 ◽  
Vol 5 (2) ◽  
pp. 171
Author(s):  
Triyono Triyono ◽  
Syakirin Al-Ghozaly ◽  
Vera Imanti

Soft skills are a set of abilities related to adjustments to oneself, others, and the environment. The counselor's personal soft skills mean the abilities or personal competencies possessed by a counselor. This study aims to determine how much the Career Development Program (CDP) influences in developing the counselor's personal soft skills of BKI students. The design of this research is quantitative experimental, using the pre-experimental design method with the type of pre-test and post-test one group design. The population of this study were the students of Islamic Guidance and Counseling (BKI) IAIN Surakarta 2015/2016, 2016/2017, and 2017/2018 academic years. The sample in this study were 90 students by taken in 3 classes in each academic year, through stratified cluster random sampling. Measurement of the counselor's personal soft skills using EPPS psychological instruments. The research results of the counselor’s personal soft skills of BKI students before and after being given Career Development Program (CDP) training, both in the second semester, 4th semester and 6th semester students groups showed significant differences. The results of paired t-test analysis obtained the pretest and posttest values with sig values = 0.000 <0.05. This means that the Career Development Program (CDP) has a significant effect on improving the counselor's personal soft skills of BKI students. The Career Development Program (CDP) is a model for the development and improvement of personal counselor’s soft skills that are effective for the students of BKI IAIN Surakarta


2017 ◽  
Vol 10 (9) ◽  
pp. 181
Author(s):  
Lidan Chen

This study reports an empirical study of an explicit instruction of corpus-aided Business English collocations and verifies its effectiveness in improving learners’ collocation awareness and learner autonomy, as a result of which is significant improvement of learners’ collocation competence. An eight-week instruction in keywords’ collocations, with the help of AntConc and self-constructed Business English Pedagogical Corpus combined with COCA general corpus and Wikipedia corpus, was imparted to 23 undergraduate learners majoring in Business English in Guangdong University of Foreign Studies. They took the collocation competence pre-test and post-test before and after the teaching experiment which was phased into two themes and submitted learning reflective journals at the end of each theme instruction and answered a questionnaire at the final end. The data from the tests, reflective journals and questionnaire collaboratively suggest that given appropriate guidance EFL Business English learners can take a more active role in raising their collocation awareness and developing learner autonomy and thus improve their collocation competence significantly. The results from the test analysis also indicate that the corpus-aided Business English collocation pedagogy is proved to be more effective for intermediate and advanced level learners rather than lower level ones. The findings have pedagogical implications for EFL Business English instructors and learners.


2014 ◽  
Vol 2 (2) ◽  
Author(s):  
Reynaldo Stevanus Pantouw ◽  
Djon Wongkar ◽  
Shane H. R. Ticoalu

Abstract: High density lipoprotein cholesterol (HDL) is a heterogeneous class of lipoproteins with density 1063 - 1:21 g / mL. HDL cholesterol has protective properties to heart because it is able to bind cholesterol and carry it to the liver for excretion. High levels of HDL in the body will increase the protection against coronary heart disease. One way to increase HDL cholesterol levels is by doing physical activity. This study have a purpose to find out the influence of zumba exercise on hemoglobin levels. Methods: This study is experimental with one group pre and post test design, that criteria includes are normal Body Mass Index, sedentary people, not consuming HDL booster supplements and not have bone abnormalities. Subjects were a total of  20 female students class of 2013 at the Medical Faculty of Nursing Science of Sam Ratulangi University. Subjects participated in exercise program three times per week for 2 weeks total exercise with duration of one hour. The HDL levels were examined before and after zumba exercise during two weeks. Data was analyzed by paired t test using SPSS. Result: Based on the research that has done from 20 subjects were obtained result in increase on HDL levels after zumba exercise for two weeks. Conclusion: Zumba exercise can increase cholesterol high density lipoprotein levels. Keywords: high density lipoprotein, zumba.     Abstrak: Latar belakang: Kolesterol High density lipoprotein (HDL) merupakan lipoprotein kelas heterogen dengan kepadatan 1.063 – 1.21 g/mL. Kolesterol HDL memiliki sifat proteksi terhadap jantung karena sifatnya yang dapat mengikat kolesterol dan membawanya ke hati untuk diekskresikan. Kadar HDL yang tinggi dalam tubuh akan meningkatkan proteksi terhadap penyakit jantung koroner. Salah satu cara meningkatkan kadar kolesterol HDL adalah dengan melakukan aktivitas fisik. Penelitian ini bertujuan untuk mengetahui pengaruh latihan zumba terhadap kadar kolesterol HDL darah. Metode: Penelitian ini bersifat eksperimental dengan rancangan one group pre and post test yang memenuhi kriteria-kriteria yaitu IMT normal, tidak rutin melakukan aktivitas fisik, tidak mengonsumsi suplemen penambah HDL, dan tidak ada kelainan tulang. Sampel penelitian yaitu mahasiswi Program Studi Ilmu Keperawatan Universitas Sam Ratulangi angkatan 2013 berjumlah 20 orang. Subjek penelitian berpartisipasi dalam latihan yang dilakukan 3 kali dalam seminggu dari total 2 minggu latihan dengan durasi 1 jam. Kadar HDL diukur sebelum latihan zumba pertama dan sesudah latihan zumba terakhir. Data dianalisis dengan uji t berpasangan menggunakan SPSS. Hasil: Berdasarkan penelitian yang telah dilakukan terhadap 20 orang subjek penelitian didapatkan hasil yaitu terjadi peningkatan kadar kolesterol HDL setelah melakukan latihan zumba selama 2 minggu. Simpulan: Latihan zumba dapat meningkatkan kadar kolesterol HDL darah. Kata Kunci: high density lipoprotein, zumba.


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