scholarly journals PENGARUH LATIHAN ZUMBA TERHADAP KADAR KOLESTEROL HIGH DENSITY LIPOPROTEIN DARAH

2014 ◽  
Vol 2 (2) ◽  
Author(s):  
Reynaldo Stevanus Pantouw ◽  
Djon Wongkar ◽  
Shane H. R. Ticoalu

Abstract: High density lipoprotein cholesterol (HDL) is a heterogeneous class of lipoproteins with density 1063 - 1:21 g / mL. HDL cholesterol has protective properties to heart because it is able to bind cholesterol and carry it to the liver for excretion. High levels of HDL in the body will increase the protection against coronary heart disease. One way to increase HDL cholesterol levels is by doing physical activity. This study have a purpose to find out the influence of zumba exercise on hemoglobin levels. Methods: This study is experimental with one group pre and post test design, that criteria includes are normal Body Mass Index, sedentary people, not consuming HDL booster supplements and not have bone abnormalities. Subjects were a total of  20 female students class of 2013 at the Medical Faculty of Nursing Science of Sam Ratulangi University. Subjects participated in exercise program three times per week for 2 weeks total exercise with duration of one hour. The HDL levels were examined before and after zumba exercise during two weeks. Data was analyzed by paired t test using SPSS. Result: Based on the research that has done from 20 subjects were obtained result in increase on HDL levels after zumba exercise for two weeks. Conclusion: Zumba exercise can increase cholesterol high density lipoprotein levels. Keywords: high density lipoprotein, zumba.     Abstrak: Latar belakang: Kolesterol High density lipoprotein (HDL) merupakan lipoprotein kelas heterogen dengan kepadatan 1.063 – 1.21 g/mL. Kolesterol HDL memiliki sifat proteksi terhadap jantung karena sifatnya yang dapat mengikat kolesterol dan membawanya ke hati untuk diekskresikan. Kadar HDL yang tinggi dalam tubuh akan meningkatkan proteksi terhadap penyakit jantung koroner. Salah satu cara meningkatkan kadar kolesterol HDL adalah dengan melakukan aktivitas fisik. Penelitian ini bertujuan untuk mengetahui pengaruh latihan zumba terhadap kadar kolesterol HDL darah. Metode: Penelitian ini bersifat eksperimental dengan rancangan one group pre and post test yang memenuhi kriteria-kriteria yaitu IMT normal, tidak rutin melakukan aktivitas fisik, tidak mengonsumsi suplemen penambah HDL, dan tidak ada kelainan tulang. Sampel penelitian yaitu mahasiswi Program Studi Ilmu Keperawatan Universitas Sam Ratulangi angkatan 2013 berjumlah 20 orang. Subjek penelitian berpartisipasi dalam latihan yang dilakukan 3 kali dalam seminggu dari total 2 minggu latihan dengan durasi 1 jam. Kadar HDL diukur sebelum latihan zumba pertama dan sesudah latihan zumba terakhir. Data dianalisis dengan uji t berpasangan menggunakan SPSS. Hasil: Berdasarkan penelitian yang telah dilakukan terhadap 20 orang subjek penelitian didapatkan hasil yaitu terjadi peningkatan kadar kolesterol HDL setelah melakukan latihan zumba selama 2 minggu. Simpulan: Latihan zumba dapat meningkatkan kadar kolesterol HDL darah. Kata Kunci: high density lipoprotein, zumba.

2013 ◽  
Vol 1 (2) ◽  
Author(s):  
Stephany Sugeha

Abstract: The prevalence of decreased levels of High Density Lipoprotein (HDL) and elevated levels of Low Density Lipoprotein (LDL) in Indonesia is quite high, until increasing diseases such as stroke, dyslipidemia and Coronary Heart Disease (CHD). Gymnastic for elder is a form of exercise that moves easily followed by the elderly and can improve the health status. This study aimed to know about influence of gymnastic for elder to the levels of HDL and LDL before and after participating. This research is an experimental design with one group pre-post test. Subjects were 30 elderly people who are in Manado BPLU drawn from a population of 48 elderly people who met the inclusion criteria. Data analysis using a paired t-test with SPSS version 20.0. There are significant differences in levels of HDL (p = 0.022) and levels of LDL cholesterol (p = 0.000), before and after participating gymnastic for elder. Conclusion: Levels of HDL and LDL before and after doing SBL were significantly different. Keywords: Gymnastic for elder, HDL, LDL   Abstrak : Prevalensi penurunan kadar High Density Lipoprotein (HDL) dan peningkatan kadar Low Density Lipoprotein (LDL) di Indonesia cukup tinggi sehingga meningkatkan penyakit seperti stroke, dislipidemia dan Penyakit Jantung Koroner (PJK). Senam bugar lansia merupakan bentuk olahraga yang gerakannya mudah diikuti oleh lansia dan dapat meningkatkan status kesehatan. Penelitian ini bertujuan untuk mengetahui pengaruh Senam Bugar Lansia terhadap kadar HDL dan LDL sebelum dan sesudah mengikuti senam bugar lansia. Penelitian ini bersifat eksperimental lapangan dengan rancangan pre-post one group test. Subjek penelitian adalah 30 lansia yang berada di BPLU Manado yang diambil dari populasi yang berjumlah 48 lansia yang memenuhi kriteria inklusi. Analisis data menggunakan t-paired test dengan program SPSS versi 20.0. Terdapat perbedaan bermakna pada kadar HDL (p=0,022) dan kadar LDL (p=0,000) sebelum dan sesudah mengikuti senam bugar lansia. Simpulan: Kadar HDL dan LDL sebelum dan sesudah melakukan senam bugar lansia berbeda secara bermakna. Kata kunci: Senam bugar lansia, HDL, LDL.


2020 ◽  
Vol 7 (2) ◽  
pp. 89
Author(s):  
Gusti Maharani ◽  
Hidayaturrahmah Hidayaturrahmah

Lipid adalah kelompok molekul alami yang berperan penting sebagai bahan bakar metabolisme, stabilitas membran sel dan komponen penting pada struktur sel didalam tubuh. Penelitian profil lipid ikan gelodok dilakukan dengan pemeriksaan kolesterol total, trigliserida, High Density Lipoprotein (HDL), dan Low Density Lipoprotein (LDL). Penelitian ini bertujuan untuk mengetahui dan menganalisa profil lipid yang ada pada ikan gelodok (Periothalmodon schlosseri) di perairan desa Kuala Lupak dan desa Tanipah, Kalimantan Selatan. Rancangan penelitian dilakukan secara eksploratif dengan menentukan lokasi pengambilan sampel. Teknik pengambilan sampel yang dilakukan adalah purposive sampling atau pengambilan sampel secara isidental berdasarkan pertimbangan heterogenitas lokasi sampel. Pemeriksaan profil lipid dilakukan dengan metode enzimatik. Hasil yang diperoleh pada penelitian ini yaitu profil lipid ikan timpakul pada perairan desa Tanipah mengandung kolesterol total sebanyak 101.17±36.06 mg/dL, HDL Kolesterol 26.5±7.06 mg/dL, LDL Kolesterol 50±26.9 mg/dL dan trigliserida sebanyak 134.8±146.07 mg/dL, sedangkan hasil profil lipid pada desa Kuala Lupak mengandung kolesterol total sebanyak 76.09±25.7 mg/dL, HDL Kolesterol 24±11.3 mg/dL, LDL Kolesterol 27.8±16.2 mg/dL, dan trigliserida 97.3±90.2 mg/dL, berdasarkan hasil yang didapatkan mengindikasikan bahwa kadar profil lipid pada ikan gelodok memiliki nilai yang lebih rendah dibandingkan dengan nilai kadar normal ikan pada umumnya.Lipids are a group of natural molecules that important role as fuel metabolism, cell membrane stability and important components of cell structure in the body. The research of lipid fish lipid profiles was carried out by examining total cholesterol, triglycerides, High Density Lipoprotein (HDL), and Low Density Lipoprotein (LDL). This research aims to determine and analyze the existing lipid profile in the gelodok (Periothalmodon schlosseri) in the waters of Kuala Lupak and Tanipah villages, South Kalimantan. The research design was carried out exploratively by determining the location of sampling. The sampling technique used was purposive sampling based on consideration of heterogeneity of sample locations. Lipid profile examination was carried out using an enzymatic method. The results obtained in this study are the lipid profile of the lead fish in the waters of Tanipah village containing total cholesterol as much as 101.17 ± 36.06 mg / dL, HDL Cholesterol 26.5 ± 7.06 mg / dL, LDL Cholesterol 50 ± 26.9 mg / dL and triglycerides as much as 134.8 ± 146.07 mg / dL, while the results of the lipid profile in Kuala Lupak village contained 76.09 ± 25.7 mg / dL total cholesterol, HDL Cholesterol 24 ± 11.3 mg / dL, Cholesterol LDL 27.8 ± 16.2 mg / dL, and triglycerides 97.3 ± 90.2 mg / dL, based on the results obtained indicate that the lipid profile level in the mackerel fish has a lower value than the normal value of fish in general.Keywords: lipid, Perithalmodon schlosseri, total cholesterol, Lipoprotein, Triglycerides


2015 ◽  
Vol 3 (2) ◽  
Author(s):  
Ade W. Arif ◽  
Djon Wongkar ◽  
Shane H. R. Ticoalu

Abstract: High Density Lipoprotein (HDL) is denser than other types of cholesterol. Blood HDL cholesterol protects the inner wall (endothelium) of blood vessels. Exercise such as Poco-poco dance can increase the HDL cholesterol level. This study aimed to obtainthe the effect of Poco-poco dance on blood HDL cholesterol level. This was an experimental study with one group pre and post test design. Subjects were 25 Pharmacy female students, Faculty of Mathematics and Sciences, Sam Ratulangi University. Subjects were selected by purposive sampling method. Data were analyzed by using paired T test. The results showed that the average of blood HDL cholesterol level of subjects before training was 57,76 mg/dL and increased to 58,44 mg/dL after 4 weeks of training. The statistical analysis showed a p value >0.05. Conclusion: There was no statistically significant increase in HDL cholesterol level after 4 weeks of Poco-poco dance.Keywords: Poco-poco dance, high density lipoproteinAbstrak: High Density Lipoprotein (HDL) merupakan kolesterol dengan partikel yang lebih padat dibandingkan kolesterol jenis lain. Kolesterol HDL darah berperan sebagai pemelihara dinding bagian dalam (lapisan endotel) pembuluh darah. Salah satu cara untuk meningkatkan kadar kolesterol HDL darah ialah dengan melakukan aktivitas fisik, antara lain senam poco-poco. Penelitian ini bertujuan untuk mengetahui pengaruh senam poco-poco terhadap kadar kolesterol HDL darah. Penelitian ini bersifat eksperimental dengan rancangan one group pre and post test. Sampel penelitian ialah mahasiswa Program Studi Farmasi Fakultas MIPA Universitas Sam Ratulangi Manado sebanyak 25 orang yang ditentukan dengan cara purposive sampling. Data dianalisis dengan uji T berpasangan. Setelah dilakukan latihan selama 4 minggu diperoleh hasil rerata kolesterol HDL sebelum latihan 57,76 mg/dL dan sesudah latihan 58,44 mg/dL. Analisis statistik menunjukkan nilai p >0,05. Simpulan: Terjadi peningkatan kadar kolesterol HDL darah setelah empat minggu senam poco-poco namun secara statistik tidak bermakna.Kata kunci: senam poco-poco, high density lipoprotein


Cells ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 574
Author(s):  
Maria Pia Adorni ◽  
Nicoletta Ronda ◽  
Franco Bernini ◽  
Francesca Zimetti

Over the years, the relationship between high-density lipoprotein (HDL) and atherosclerosis, initially highlighted by the Framingham study, has been revealed to be extremely complex, due to the multiple HDL functions involved in atheroprotection. Among them, HDL cholesterol efflux capacity (CEC), the ability of HDL to promote cell cholesterol efflux from cells, has emerged as a better predictor of cardiovascular (CV) risk compared to merely plasma HDL-cholesterol (HDL-C) levels. HDL CEC is impaired in many genetic and pathological conditions associated to high CV risk such as dyslipidemia, chronic kidney disease, diabetes, inflammatory and autoimmune diseases, endocrine disorders, etc. The present review describes the current knowledge on HDL CEC modifications in these conditions, focusing on the most recent human studies and on genetic and pathophysiologic aspects. In addition, the most relevant strategies possibly modulating HDL CEC, including lifestyle modifications, as well as nutraceutical and pharmacological interventions, will be discussed. The objective of this review is to help understanding whether, from the current evidence, HDL CEC may be considered as a valid biomarker of CV risk and a potential pharmacological target for novel therapeutic approaches.


Author(s):  
Dilay Karabulut ◽  
Mustafa Gürkan Yenice

Objective: Elevated uric acid (UA) and low levels of high-density lipoprotein (HDL) cholesterol are associated with cardiovascular events and mortality. Erectile dysfunction (ED) has been considered an early marker of cardiovascular disease (CVD). Therefore, this study aimed to investigate the uric acid/ HDL ratio (UHR) as a nowel marker in patients with ED. Materials and Methods: The study included 147 patients with a mean age of 50 years (range 32-76 years). Retrospective analyses were performed on the patients who were admitted to urology outpatient clinics. The laboratory parameter results were retrieved from the hospital medical records, and the UHR value was calculated. Patients were categorized into three groups according to the International Index of Erectile Function (IIEF) score. UHR was compared between groups, and its predictive value was evaluated using regression analysis and ROC curve analysis. Results: Age was found to be significantly different in all three groups (Groups 1-2, p=0.001; Groups 1-3, p=0.000; Groups 2-3, p=0.001). It was observed that the degree of ED increased with age. The values of UA and HDL were similar in all groups (p>0.05). In contrast, the UHR value was statistically significantly higher 0.15 (0.083-0.288, p =0.047) in the moderate-severe ED (Group 3). ROC curve analyses revealed that UHR predicted severe ED (IIEF 5-11) with 42.9% sensitivity and 87.3% specificity (AUC:0.66, CI 95% 0.538-0.781, p=0.019). Conclusion: UHR may serve as a severe ED indicator in patients admitted to the cardiology outpatient clinic since it has a significant association with a low IIEF score.


2021 ◽  

Background: Dyslipidemia, a genetic and multifactorial disorder of lipoprotein metabolism, is defined by elevations in levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), non-high-density lipoprotein cholesterol (non–HDL-C), triglyceride, or some combination thereof, as well as lower levels of high-density lipoprotein (HDL) cholesterol. Objectives: This study aimed to investigate the prevalence and predictors of dyslipidemia in children and adolescents in the Yazd Greater Area, Yazd, Iran. Methods: This cross-sectional study was conducted as a part of the national project implemented in Yazd Greater Area, Yazd, Iran. The sampling was performed using a multi-stage cluster sampling method on three age groups of girls and boys (6-9, 10-14, and 15-18 years old). Out of the total 1,035 children and adolescents who participated in this study, only 784 participants remained in the study until the end. Data collection was performed using lifestyle questionnaires including Kiddie-SADS-Present and Lifetime Version. Results: The prevalence of high triglyceride was estimated at 1.4% and 4.2% in 6-9 and 10-18 years old children and adolescents, respectively. The prevalence of high cholesterol, LDL, and HDL was 3.2%, 3.2%, and 25.6%, respectively. The prevalence of dyslipidemia in the total population of children and adolescents in terms of demographic variables was 64.6% and 57.3% in boys and girls, respectively (P=0.038). Gender and increase in body mass index were significantly associated with dyslipidemia with OR=1.35; 95% CI: 1.01-1.81 and OR=13.781; 95% CI: 3.78- 46.43, respectively. However, after adjustment for other factors, only an increase in BMI was significantly associated with dyslipidemia (OR=16.08; 95% CI: 4.49-57.59). Conclusions: Overweight and obese adolescents had a higher concentration of serum blood triglycerides, compared to other adolescents. Weight control, lifestyle modification, and diet are three ways to reduce lipid disorders in adolescents.


2018 ◽  
Vol 35 (5) ◽  
pp. 438-444 ◽  
Author(s):  
Farzin Brian Boudi ◽  
Nicholas Kalayeh ◽  
Mohammad Reza Movahed

Objective: Acute coronary syndrome is frequently complicated by rhythm disturbances, yet any association between high-density lipoprotein (HDL) cholesterol levels and arrhythmias in the setting of non-ST-segment elevation myocardial infarction (non-STEMI) is uncertain. The goal of this study was to evaluate any association between HDL-cholesterol levels and arrhythmias in the setting of non-STEMI. Methods: Retrospective data from Phoenix Veterans Affair Medical Center records were utilized for our study. A total of 6881 patients were found who presented during 2000 to 2003 with non-STEMI with available fasting lipid panels collected within the first 24 hours of admission. Patients were followed for the development of rhythm disturbances up to 6 years after initial presentation, with a mean follow up of 1269 days. Results: We found that high triglycerides/HDL and low-density lipid/HDL ratios were predictive of arrhythmias. However, low HDL levels had strongest association with highest odds ratio (OR) for development of arrhythmias (for HDL <31 mg/dL, OR = 3.72, 95% confidence interval [CI] = 2.55-5.44, P < .05) in patients with diabetes and (for HDL < 31 mg/dL, OR = 3.69, 95% CI = 2.85-4.71, P < .05) in patients without diabetes. Using multivariate analysis adjusting for comorbidities, low HDL level remained independently associated with arrhythmias. Conclusions: Patients with low HDL levels during hospitalization with non-STEMI have a greater risk of developing cardiac rhythm disturbances independent of other risk factors. These data suggest a possible protective role of HDL in preventing arrhythmias in the setting of acute coronary syndrome.


Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Catherine Rahilly-Tierney ◽  
Howard D Sesso ◽  
J. Michael Gaziano ◽  
Luc Djousse

BACKGROUND: Few studies have examined prospectively the relationship between baseline high-density lipoprotein (HDL) cholesterol and longevity. OBJECTIVES: We sought to examine whether higher HDL levels were associated with lower risk of all-cause, cardiovascular (CVD), and non-CVD mortality prior to age 90 in the Physicians’ Health Study (PHS). METHODS: We considered a baseline cohort of 1351 PHS participants who provided bloods between 1997 and 2001 and were old enough to reach age 90 by March 4, 2009. Included subjects had complete baseline data on HDL and total cholesterol; lifestyle factors including smoking, exercise, alcohol consumption, and BMI; and comorbidities including hypertension, diabetes mellitus, congestive heart failure, cancer, and stroke. We used Cox proportional hazards to determine the HRs and 95% CIs for all-cause, CVD, and non-CVD mortality prior to age 90, adjusting for baseline age, co-morbidities, and non-HDL cholesterol. RESULTS: At baseline, the cohort had a mean (SD) age of 81.9 (2.9) years and a mean (SD) HDL cholesterol of 44.8(16.5) mg/dL. After a mean follow-up of 6.8 years (maximum 12.3 years), 501 (37.1%) of men died prior to age 90. In multi-variable adjusted analyses, men in the highest HDL-C quartile (≥54.1 mg/dL) had a 28% lower risk (HR 0.72, 95% CI 0.55-0.95) of all-cause mortality prior to age 90 compared to men in the lowest HDL-C quartile (<32.8 mg/dL). From the lowest to highest HDL quartile, age-adjusted HR(95%CI) for CVD mortality prior to age 90 were 0.66 (0.44-0.99), 0.58 (0.38-0.90), and 0.53 (0.34-0.82) (p for trend 0.004). There was no significant association between baseline HDL cholesterol and non-CVD death. CONCLUSION: In a cohort of older male physicians with long-term follow-up, baseline HDL cholesterol was inversely associated with the risk of dying prior to age 90, largely explained by an inverse association between HDL and CVD mortality.


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