scholarly journals Folikel Pre-Ovulatori Sapi PO Dara yang Distimulasi Menggunakan PMSG Dosis Rendah

2020 ◽  
Vol 8 (3) ◽  
pp. 1-7
Author(s):  
Krido Brahmo Putro ◽  
Amrozi . ◽  
Adi Winarto ◽  
Arief Boediono ◽  
Wasmen Manalu
Keyword(s):  
Intrauterine Programming

Penelitian ini bertujuan untuk mengetahui perkembangan folikel sapi PO dara yang distimulasi menggunakan PMSG dosis rendah (dosis non-superovulasi) dan perolehan folikel dominan pre-ovulatori sebagai informasi dasar untuk penerapan intrauterine programming pada sapi. Sapi PO dara berjumlah sembilan ekor dibagi ke dalam tiga kelompok dosis PMSG yaitu kontrol (NaCl 0.9% sebagai placebo), dosis PMSG 0.5, dan 1.0 IU/kg BB. Injeksi PMSG dilakukan pada awal gelombang folikel ke-2 berdasarkan perubahan dinamika ovari yang dikonfirmasi menggunakan USG diikuti injeksi PGF2α 48 jam kemudian. Perkembangan folikel sejak injeksi PMSG hingga terbentuknya pre-ovulatori folikel (POF) diamati dan dipetakan menggunakan USG. Jumlah POF tertinggi terdapat pada dosis PMSG 1.0 IU/kg BB (4.67+1.67) secara signifikan (P<0.05), sedangkan POF yang terbentuk pada dosis PMSG 0.5 IU/kg BB berjumlah satu, sama dengan kelompok kontrol (P>0.05). Meskipun jumlah POF yang terbentuk berjumlah satu, namun rataan diameter dan volume kelompok sapi dosis 0.5 IU/kg BB lebih besar 16.13% dan 57.14% secara berurutan dibandingkan kelompok kontrol, diikuti oleh dosis 1.0 IU/kg BB dengan nilai tertinggi secara signifikan (P<0.05). Berdasarkan hasil tersebut dapat diketahui bahwa PMSG 0.5 IU/kg BB dapat terkontrol sehingga dapat digunakan sebagai metode pendekatan intrautering programming pada hewan monotokus.

Intrauterine Programming of Diabetes and Adiposity

2015 ◽  
Vol 4 (4) ◽  
pp. 418-428 ◽  
Author(s):  
Ashutosh Singh Tomar ◽  
Divya Sri Priyanka Tallapragada ◽  
Suraj Singh Nongmaithem ◽  
Smeeta Shrestha ◽  
Chittaranjan S. Yajnik ◽  
...  
Keyword(s):  
Intrauterine Programming

scholarly journals Diet Enriched with Olive Oil Attenuates Placental Dysfunction in Rats with Gestational Diabetes Induced by Intrauterine Programming

2018 ◽  
Vol 62 (19) ◽  
pp. 1800263 ◽  
Author(s):  
Evangelina Capobianco ◽  
Dalmiro Gomez Ribot ◽  
Daiana Fornes ◽  
Theresa L. Powell ◽  
Cecilia Levieux ◽  
...  
Keyword(s):  
Gestational Diabetes ◽  
Olive Oil ◽  
Placental Dysfunction ◽  
Intrauterine Programming

Placental alterations in a new experimental model of gestational diabetes generated by intrauterine programming in the offspring of mild diabetic rats

Placenta ◽  
2014 ◽  
Vol 35 (9) ◽  
pp. A27
Author(s):  
Evangelina Capobianco ◽  
Daiana Fornes ◽  
Magalí Pelesson ◽  
Verónica White ◽  
Alicia Jawerbaum
Keyword(s):  
Gestational Diabetes ◽  
Experimental Model ◽  
Diabetic Rats ◽  
Intrauterine Programming

Intrauterine programming of lipid metabolic alterations in the heart of the offspring of diabetic rats is prevented by maternal diets enriched in olive oil

2015 ◽  
Vol 59 (10) ◽  
pp. 1997-2007 ◽  
Author(s):  
Evangelina Capobianco ◽  
Magalí Pelesson ◽  
Valeria Careaga ◽  
Daiana Fornes ◽  
Ivana Canosa ◽  
...  
Keyword(s):  
Olive Oil ◽  
Diabetic Rats ◽  
Metabolic Alterations ◽  
Intrauterine Programming

Metabolic abnormalities in the fetal liver of rats with gestational diabetes induced by intrauterine programming

Placenta ◽  
2015 ◽  
Vol 36 (4) ◽  
pp. 492
Author(s):  
Daiana Fornes ◽  
Romina Higa ◽  
Ivana Linenberg ◽  
Evangelina Capobianco ◽  
Alicia Jawerbaum
Keyword(s):  
Gestational Diabetes ◽  
Fetal Liver ◽  
Metabolic Abnormalities ◽  
Intrauterine Programming

scholarly journals Apolipoprotein E/intrauterine undernutrition interaction and hypercholesterolemia in children

2008 ◽  
pp. 965-968
Author(s):  
P Szitányi ◽  
H Pistulková ◽  
JA Hubáček ◽  
H Stuchlíková ◽  
R Poledne
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Gene Polymorphism ◽  
Apolipoprotein E ◽  
High Cholesterol ◽  
Apo E ◽  
Low Cholesterol ◽  
Intrauterine Programming

The inconsistency of data regarding intrauterine programming of cardiovascular risk factors may be largely caused by genetic predisposition and later lifestyle. We analyzed whether low birth weight and apolipoprotein E (Apo E) polymorphism participate in the onset of hypercholesterolemia in children. Our approach was based on hypothesis that genetically enhanced susceptibility of different individuals might influence the effects of intrauterine programming. Two groups were selected from 2000 children at the beginning of an ongoing study: high-cholesterol group (HCG, n=67) and low-cholesterol group as a control (LCG, n=72). Both groups were divided into tertilles according to birth weight and we compared birth weight and apo E gene polymorphism between and within groups. The birth weight in HCG was 0.3 kg lower than the controls (p<0.001). The frequency of apoE4 was 31 % in HCG and only 10 % in LCG. The frequency of apoE4+ genotypes was not significantly different between tertilles based on birth weight in HCG. We suppose that intrauterine undernutrition, demonstrated by a lower birth weight, participates in the development of hypercholesterolemia already in childhood. The effects of low birth weight and the candidate gene - apoE, are synergic.

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