Association between serum aminotransferase enzymes–lipid profile ratio and spontaneous HCV clearance in blood donors

2016 ◽  
Vol 11 (1) ◽  
pp. 19-29 ◽  
Author(s):  
Ashraf A Tabll ◽  
Marwa A Kodous ◽  
Ayman T Abbas ◽  
Mohamed M Omran ◽  
Elsherbeny H Elsayed
2006 ◽  
Vol 66 (2) ◽  
pp. 184-188 ◽  
Author(s):  
V P van Halm ◽  
M M J Nielen ◽  
M T Nurmohamed ◽  
D van Schaardenburg ◽  
H W Reesink ◽  
...  

Author(s):  
Romyla Bourouba

Preeclampsia (PE) is a multisystem pregnancy disease inflecting maternal, fetal mortality and morbidity. This case-control study aims to determine the biochemical changes in lipid profile, hepatic and renal functions among sixty preeclamptic women compared to sixty age-matching normotensive pregnant women from the Maternity Hospital in Sétif, Algeria. Several biomarkers were collected and have been determined by appropriate kits. Association between various parameters was evaluated using Pearson’s correlation coefficient, with significance at P<0.05. The PE women showed a significant increase in serum aminotransferase, gamma-glutamyl-transferase, alkaline phosphatase, as well as total cholesterol, triglycerides, urea, uric acid, and creatinine levels. However, a significant decrease in platelets, total protein, albumin, and plasma sodium levels were found in PE group. A positive correlation between aminotransferases and renal biomarkers was observed.PE has deleterious effects on liver and renal functions, and could be predicted by evaluating hepatic and renal biomarkers as well as lipid profile in the early stage of disease, for targeted prevention strategies in our population. Further studies on genetic assessment in cases of PE are needed for a better understanding of this disease’s pathophysiology in Algeria.


2020 ◽  
Vol 08 (04) ◽  
pp. 81-95
Author(s):  
Kingsley Kalawari Odiabara ◽  
Edna Ogechi Nwachuku ◽  
Ndokiari Boisa ◽  
Ebirien-Agana Samuel Bartimaeus

2013 ◽  
pp. 39 ◽  
Author(s):  
Akinsegun Akinbami ◽  
Uche ◽  
Adediran ◽  
Damulak ◽  
Adeyemo ◽  
...  
Keyword(s):  

Author(s):  
Waode Rusdiah ◽  
Rachmawati Muhiddin ◽  
Mansyur Arif

Profil lipid merupakan petunjuk untuk menilai faktor kebahayaan penyakit jantung koroner, terutama jika terdapat bukti adanyaperoksidase lipid. Beberapa laporan telah mengaitkan donor darah secara regular dengan menurunnya tolok ukur profil lipid. Donordarah secara regular akan menurunkan kadar zat besi dan pada gilirannya akan menurunkan peroksidase lipid. Penelitian ini bertujuanmengetahui kadar profil lipid di pendonor darah regular dan non-regular, menggunakan pendekatan secara potong lintang denganmengambil sampel darah di UTD Transfusi Darah Dinas Kesehatan Propinsi Sulawesi Selatan. Diperoleh sebanyak 60 sampel darah yangberasal dari donor regular 30 orang (50,0%) dan non-reguler 30 orang (50,0%). Rentang umur 18–40 tahun 27 orang (45,0%) dan41-60 tahun 33 orang (55,0%). Di telitian ini kelompok pendonor darah regular rerata memiliki kolesterol total 157,93 mg/dL dan LDL95,33 mg/dL yang lebih rendah dibandingkan dengan kelompok non-regular dan menunjukkan perbedaan bermakna secara statistik(ρ=0,001). Kadar HDL secara bermakna lebih tinggi (ρ=0,015) di kelompok non-regular 43,20 mg/dL dibandingkan dengan kelompokregular 35,50 mg/dL. Kadar Trigliserida (ρ=0,673) menunjukkan tidak terdapat perbedaan bermakna antara kelompok regular dannon-regular. Donor secara teratur dapat memberikan perlindungan terhadap penyakit kardiovaskular seperti yang tercermin dari nilairerata kolesterol total dan kadar LDL yang secara bermakna lebih rendah di pendonor darah regular daripada non-reguler.


Author(s):  
Romyla Bourouba ◽  
Kaouthar Benantar ◽  
Chaima Ayati ◽  
Lina Hedna ◽  
Kenza Gherbi ◽  
...  

Preeclampsia (PE) is a multisystem pregnancy disease inflecting maternal and fetal mortality and morbidity. This case-control study aims to determine the biochemical changes in lipid profile, hepatic and renal functions among sixty late-onset preeclamptic women compared to sixty age-matching normotensive pregnant women from the Maternity Hospital in Sétif, Algeria. Several biomarkers were collected and have been determined by appropriate kits. Association between various parameters was evaluated using Pearson’s correlation coefficient, with significance at p<0.05. The PE women showed a significant increase in serum aminotransferase, gamma-glutamyl-transferase, alkaline phosphatase, as well as total cholesterol, triglycerides, urea, uric acid, and creatinine levels. However, a significant decrease in platelets, total protein, albumin, and plasma sodium levels was found in PE group. A positive correlation between aminotransferases and renal biomarkers was observed. PE has deleterious effects on liver and renal functions, and complication’s progression could be predicted by evaluating hepatic and renal biomarkers as well as lipid profile. Further studies on maternal and neonatal outcomes in cases of PE are needed for a better understanding of this disease’s pathophysiology in Algeria.


1996 ◽  
Vol 6 (1) ◽  
pp. 31-36 ◽  
Author(s):  
F. M. Cowan ◽  
A. M. Johnson ◽  
J. Wadsworth ◽  
M. Brennan

Author(s):  
Melek Yanasik ◽  
Fatma Savran Oguz ◽  
Sevgi Kalayoglu Besisik ◽  
Mukadder Huslu ◽  
Gulyuz Ozturk ◽  
...  
Keyword(s):  

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