scholarly journals Plasmonic Based Biosensors: The Future in Biomedical Applications (Preprint)

2020 ◽  
Author(s):  
Omar Cavazos ◽  
Maurizio Manzo

UNSTRUCTURED The use of plasmonic sensors has been an important innovative method for accomplishing various tasks. This review article discusses a broad scope of plasmonic sensors in bio-medical applications. Most of the devices and methods discussed are based on the surface plasmon resonance (SPR). However, other topics discussed include the localized surface plasmon resonance and the whispering gallery mode (WGM) phenomenon. This paper reviews a wide variety of contributions to biosensing.

10.2196/17781 ◽  
2021 ◽  
Vol 6 (2) ◽  
pp. e17781
Author(s):  
Maurizio Manzo ◽  
Omar Cavazos ◽  
Zhenhua Huang ◽  
Liping Cai

Background The term “plasmonic” describes the relationship between electromagnetic fields and metallic nanostructures. Plasmon-based sensors have been used innovatively to accomplish different biomedical tasks, including detection of cancer. Plasmonic sensors also have been used in biochip applications and biosensors and have the potential to be implemented as implantable point-of-care devices. Many devices and methods discussed in the literature are based on surface plasmon resonance (SPR) and localized SPR (LSPR). However, the mathematical background can be overwhelming for researchers at times. Objective This review article discusses the theory of SPR, simplifying the underlying physics and bypassing many equations of SPR and LSPR. Moreover, we introduce and discuss the hybrid whispering gallery mode (WGM) sensing theory and its applications. Methods A literature search in ScienceDirect was performed using keywords such as “surface plasmon resonance,” “localized plasmon resonance,” and “whispering gallery mode/plasmonic.” The search results retrieved many articles, among which we selected only those that presented a simple explanation of the SPR phenomena with prominent biomedical examples. Results SPR, LSPR, tilted fiber Bragg grating, and hybrid WGM phenomena were explained and examples on biosensing applications were provided. Conclusions This minireview presents an overview of biosensor applications in the field of biomedicine and is intended for researchers interested in starting to work in this field. The review presents the fundamental notions of plasmonic sensors and hybrid WGM sensors, thereby allowing one to get familiar with the terminology and underlying complex formulations of linear and nonlinear optics.


Sensors ◽  
2021 ◽  
Vol 21 (16) ◽  
pp. 5262
Author(s):  
Qilin Duan ◽  
Yineng Liu ◽  
Shanshan Chang ◽  
Huanyang Chen ◽  
Jin-hui Chen

Surface plasmonic sensors have been widely used in biology, chemistry, and environment monitoring. These sensors exhibit extraordinary sensitivity based on surface plasmon resonance (SPR) or localized surface plasmon resonance (LSPR) effects, and they have found commercial applications. In this review, we present recent progress in the field of surface plasmonic sensors, mainly in the configurations of planar metastructures and optical-fiber waveguides. In the metastructure platform, the optical sensors based on LSPR, hyperbolic dispersion, Fano resonance, and two-dimensional (2D) materials integration are introduced. The optical-fiber sensors integrated with LSPR/SPR structures and 2D materials are summarized. We also introduce the recent advances in quantum plasmonic sensing beyond the classical shot noise limit. The challenges and opportunities in this field are discussed.


Sensors ◽  
2021 ◽  
Vol 21 (3) ◽  
pp. 819
Author(s):  
Seunghun Lee ◽  
Hyerin Song ◽  
Heesang Ahn ◽  
Seungchul Kim ◽  
Jong-ryul Choi ◽  
...  

Applying fiber-optics on surface plasmon resonance (SPR) sensors is aimed at practical usability over conventional SPR sensors. Recently, field localization techniques using nanostructures or nanoparticles have been investigated on optical fibers for further sensitivity enhancement and significant target selectivity. In this review article, we explored varied recent research approaches of fiber-optics based localized surface plasmon resonance (LSPR) sensors. The article contains interesting experimental results using fiber-optic LSPR sensors for three different application categories: (1) chemical reactions measurements, (2) physical properties measurements, and (3) biological events monitoring. In addition, novel techniques which can create synergy combined with fiber-optic LSPR sensors were introduced. The review article suggests fiber-optic LSPR sensors have lots of potential for measurements of varied targets with high sensitivity. Moreover, the previous results show that the sensitivity enhancements which can be applied with creative varied plasmonic nanomaterials make it possible to detect minute changes including quick chemical reactions and tiny molecular activities.


2013 ◽  
Author(s):  
Kristopher J. Rowland ◽  
Alexandre François ◽  
Beniamino Sciacca ◽  
Tanya M. Monro

2021 ◽  
pp. 2100653
Author(s):  
Gyeong‐Su Park ◽  
Kyung Suk Min ◽  
Hyuksang Kwon ◽  
Sangwoon Yoon ◽  
Sangwon Park ◽  
...  

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