scholarly journals Incorporating potable water sources and use habits into surveys that improve surrogate exposure estimates for water contaminants: the case of bisphenol A

2013 ◽  
Vol 12 (1) ◽  
pp. 81-93 ◽  
Author(s):  
Syam S. Andra ◽  
Konstantinos C. Makris
Keyword(s):  
Bisphenol A ◽  
Water Consumption ◽  
Tap Water ◽  
Daily Intake ◽  
Human Biomonitoring ◽  
Water Sources ◽  
Water Contact ◽  
Water Contaminants ◽  
Contact Materials ◽  
Consumption Rates

Human biomonitoring studies for water contaminants are often accompanied by surveys relying solely on total drinking water consumption rates, thus, failing to account for specific water sources (bottled and tap water) and use habits, such as water used for preparing cold/hot beverages (coffee, tea, juice, etc.). Despite the extensive use of bisphenol A (BPA) in polycarbonate (PC)-based water contact materials, rarely do BPA biomonitoring studies focus on various PC water uses and sources. Better resolved water consumption rates could reduce the uncertainty associated with surrogate daily BPA intake estimates using fine-tuned surveys. This approach provided a proof of concept on inclusion of water consumption from various sources and uses into estimates of daily intake for water contaminants like BPA found in water-contact materials. The next steps would be in quantifying the extent of improvement in exposure assessment that adds value to refined survey designs.

scholarly journals Target-Induced Aggregation of Gold Nanoparticles for Colorimetric Detection of Bisphenol A

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Sung Hyun Hwang ◽  
Sehan Jeong ◽  
Hyung Joo Choi ◽  
Hyunmin Eun ◽  
Min Geun Jo ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Bisphenol A ◽  
Tap Water ◽  
Colorimetric Detection ◽  
Daily Intake ◽  
Consumer Products ◽  
Dna Aptamer ◽  
Site Quality ◽  
Local Market ◽  
Induced Aggregation

Bisphenol A (BPA) is used in a wide variety of consumer products owing to its beneficial properties of optical clarity, shatter resistance, and heat resistance. However, leached BPA has been shown to disturb the endocrine system and could cause cancer even at low concentrations, which has led to public concern. To reduce the toxic effects caused by BPA, it is important to monitor the BPA levels and its presence in products in a simple, rapid, and on-site manner. Here, we propose a new colorimetric strategy for the simple and rapid detection of BPA employing a DNA aptamer, a cationic surfactant, and gold nanoparticles (AuNPs). Using the developed system, the presence of BPA can be successfully determined based simply on a visually detectable color change from red to blue, triggered by aggregate formation of the AuNPs, which can be monitored even with the naked eye. Under the optimized conditions, this system could detect BPA with excellent selectivity and sensitivity, and its high performance was validated in the receipt obtained from local market and BPA-spiked tap water samples, ensuring its practical applicability. Moreover, the limit of the detection of the system was determined to be 97 nM, which is below the current tolerable daily intake level, demonstrating its suitability for toxicity assessment and on-site quality control in a more economical manner when compared with conventional methods.

scholarly journals Italian Children Exposure to Bisphenol A: Biomonitoring Data from the LIFE PERSUADED Project

2021 ◽  
Vol 18 (22) ◽  
pp. 11846
Author(s):  
Sabrina Tait ◽  
Fabrizia Carli ◽  
Luca Busani ◽  
Demetrio Ciociaro ◽  
Veronica Della Latta ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Rural Areas ◽  
Urban Areas ◽  
Daily Intake ◽  
Human Biomonitoring ◽  
Tolerable Daily Intake ◽  
Young Population ◽  
The North ◽  
Children Exposure ◽  
Italian Children

A human biomonitoring (HBM) study on bisphenol A (BPA) in Italian children and adolescents was performed within the LIFE PERSUADED project, considering the residing areas, sex and age. The median urinary BPA level was 7.02 µg/L, with children living in the South of Italy or in urban areas having higher levels than those residing in the North or in rural areas. Children aged 4–6 years had higher BPA levels than those aged 7–10 and 11–14 years, but no differences were detected between sexes. The exposure in Italian children was higher compared to children from other countries, but lower than the HBM guidance value (135 µg/L). The estimated daily intake was 0.17 μg/kg body weight (bw) per day, about 24-fold below the temporary Tolerable Daily Intake of 4 μg/kg bw per day established by the European Food Safety Authority. However, this threshold was exceeded in 1.44% of the enrolled children, raising concern about the overall exposure of Italian young population.

Effect of Wastewater on the Soil and Irrigation Process: A Laboratory Study

2017 ◽  
Vol 1 (1) ◽  
pp. 46-55 ◽  
Author(s):  
Athar Hussain ◽  
Manjeeta Priyadarshi ◽  
Saif Said ◽  
Suraj Negi
Keyword(s):  
Heavy Metals ◽  
Tap Water ◽  
Sewage Treatment ◽  
Daily Intake ◽  
Sewage Treatment Plant ◽  
Treatment Plant ◽  
Treated Wastewater ◽  
Surface Water Resources ◽  
Industrial Sewage ◽  
Concentration Levels

Most of the industrial sewage effluents used for irrigation contains heavy metals which cause toxicity to crop plants as the soils are able to accumulate heavy metal for many years. The vegetables grown for the present study were irrigated with treated wastewater brought from a nearby full-scale sewage treatment plant at different compositions along with tap water as a control. The concentration levels of the Cd, Co, Cu, Mn and Zn in the soil were found to below the toxic limits as prescribed in literature. Daily Intake Metals (DIM) values suggest that the consumption of plants grown in treated wastewater and tap water is nearly free of risks, as the dietary intake limits of Cu, Fe, Zn and Mn. The Enrichment Factor for the treated wastewater irrigated soil was found in order Zn> Ni> Pb> Cr> Cu> Co> Mn> Cd. Thus, treated wastewater can be effectively used for irrigation. This will have twofold significant environmental advantages: (1) helpful to reduce the groundwater usage for irrigation and (2) helpful to reduce the stress on surface water resources.

scholarly journals Examining Recent Trends in the Racial Disparity Gap in Tap Water Consumption: NHANES 2011–2018

2021 ◽  
pp. 1-20
Author(s):  
Asher Y. Rosinger ◽  
Anisha I. Patel ◽  
Francesca Weaks
Keyword(s):  
Water Consumption ◽  
Tap Water ◽  
Ethnic Disparities ◽  
Prevalence Ratio ◽  
Bottled Water ◽  
Water Crisis ◽  
Cross Sectional ◽  
The Us ◽  
Recent Trends ◽  
Nationally Representative

Abstract Objective As tap water distrust has grown in the US with greater levels among Black and Hispanic households, we aimed to examine recent trends in not drinking tap water including the period covering the US Flint Water Crisis and racial/ethnic disparities in these trends. Design Cross-sectional analysis. We used log-binomial regressions and marginal predicted probabilities examined US nationally-representative trends in tap and bottled water consumption overall and by race/ethnicity. Setting The National Health and Nutrition Examination Survey data, 2011–2018. Participants Nationally-representative sample of 9,439 children aged 2-19 and 17,268 adults. Results Among US children and adults, respectively, in 2017-2018 there was a 63% (adjusted prevalence ratio [PR]:1.63, 95%CI: 1.25-2.12, p<0.001) and 40% (PR:1.40, 95%CI: 1.16-1.69, p=0.001) higher prevalence of not drinking tap water compared to 2013-2014 (pre-Flint Water Crisis). For Black children and adults, the probability of not drinking tap water increased significantly from 18.1% (95%CI: 13.4-22.8) and 24.6% (95%CI: 20.7-28.4) in 2013–14 to 29.3% (95%CI: 23.5-35.1) and 34.5% (95%CI: 29.4-39.6) in 2017–2018. Among Hispanic children and adults, not drinking tap water increased significantly from 24.5% (95%CI: 19.4-29.6) and 27.1% (95%CI: 23.0-31.2) in 2013-14 to 39.7% (95%CI: 32.7-46.8) and 38.1% (95%CI: 33.0-43.1) in 2017-2018. No significant increases were observed among Asian or white persons between 2013-14 and 2017-18. Similar trends were found in bottled water consumption. Conclusions This study found persistent disparities in the tap water consumption gap from 2011–2018. Black and Hispanics’ probability of not drinking tap water increased following the Flint Water Crisis.

A fluorescent aptasensor based on berberine for ultrasensitive detection of bisphenol A in tap water

2021 ◽  
Author(s):  
Yuxin Wei ◽  
Yangyang Zhou ◽  
Yanli Wei ◽  
Chuan Dong ◽  
Li Wang
Keyword(s):  
Bisphenol A ◽  
Human Health ◽  
Food Packaging ◽  
Tap Water ◽  
Water Systems ◽  
Ultrasensitive Detection ◽  
Its Analysis ◽  
Potential Impact ◽  
Fluorescent Aptasensor

The residues of bisphenol A (BPA) in food packaging and water systems have potential impact on human health, therefore, its analysis and detection has drawn people's attention. In this work,...

scholarly journals Metabolic syndrome and endocrine disrupting chemicals: exposure and health effects

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
E Haverinen ◽  
R Lange ◽  
H Tolonen
Keyword(s):  
Metabolic Syndrome ◽  
Bisphenol A ◽  
Health Effects ◽  
Endocrine Disrupting Chemicals ◽  
Positive Association ◽  
Human Biomonitoring ◽  
European Population ◽  
Priority Substances ◽  
Metabolic Disturbances ◽  
Endocrine Disrupting

Abstract Increasing prevalence of metabolic syndrome (MetS) is causing significant health burden among the European population. Current knowledge supports the notion that endocrine disrupting chemicals (EDCs) interfere with human metabolism and hormonal balance, contributing to the conventionally recognized life-style related risk factors for MetS. In relation to the Human biomonitoring initiative (HBM4EU) five priority substances (Bisphenol A, Per- and polyfluoroalkyl substances (PFASs), Phthalates, Cadmium and Arsenic) and their association with adverse metabolic health effects were examined. A methodological framework for scoping reviews was followed to increase consistency and transparency throughout the process. A literature review was conducted to identify epidemiological studies focusing on the association between MetS or its individual components and the five HBM4EU priority substances. Human biomonitoring studies have been able to present evidence supporting EDC exposure and development of individual MetS components; however the strength of the association varies between the components and EDCs. Most of the identified literature examined Bisphenol A and Phthalate exposure, usually targeting obesity, anthropometrics or glucose metabolism. Evidence suggests a positive association between Bisphenol A and Phthalate exposure and obesity-related components. The substance group of PFASs indicated weakest association, as the results were inconsistent and were suggestive only for a positive association with development of dyslipidaemia. Current evidence on metabolic disturbances and EDCs are inconclusive and fragmented, hence establishing harmonized and standardized human biomonitoring procedures among the European population are needed. Rigorous and ongoing human biomonitoring in combination with health monitoring could provide comprehensive information on EDC exposure and association of metabolic disturbances. Key messages EDC exposure is ubiquitous within European population, hence more human biomonitoring in combination with health surveys is needed to strengthen knowledge on human’s metabolic health. MetS is an increasing global health concern, which requires novel approaches to tackle the challenge.

scholarly journals Changes Caused by Low Doses of Bisphenol A (BPA) in the Neuro-Chemistry of Nerves Located in the Porcine Heart

Animals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 780
Author(s):  
Krystyna Makowska ◽  
Slawomir Gonkowski
Keyword(s):  
Bisphenol A ◽  
Endocrine Disruptor ◽  
Sympathetic Innervation ◽  
Daily Intake ◽  
Everyday Objects ◽  
Living Organisms ◽  
The Impact ◽  
Heart Wall ◽  
Cholinergic Structures

Bisphenol A (BPA) contained in plastics used in the production of various everyday objects may leach from these items and contaminate food, water and air. As an endocrine disruptor, BPA negatively affects many internal organs and systems. Exposure to BPA also contributes to heart and cardiovascular system dysfunction, but many aspects connected with this activity remain unknown. Therefore, this study aimed to investigate the impact of BPA in a dose of 0.05 mg/kg body weight/day (in many countries such a dose is regarded as a tolerable daily intake–TDI dose of BPA–completely safe for living organisms) on the neurochemical characterization of nerves located in the heart wall using the immunofluorescence technique. The obtained results indicate that BPA (even in such a relatively low dose) increases the number of nerves immunoreactive to neuropeptide Y, substance P and tyrosine hydroxylase (used here as a marker of sympathetic innervation). However, BPA did not change the number of nerves immunoreactive to vesicular acetylcholine transporter (used here as a marker of cholinergic structures). These observations suggest that changes in the heart innervation may be at the root of BPA-induced circulatory disturbances, as well as arrhythmogenic and/or proinflammatory effects of this endocrine disruptor. Moreover, changes in the neurochemical characterization of nerves in the heart wall may be the first sign of exposure to BPA.

scholarly journals Human biomonitoring initiative (HBM4EU): Human biomonitoring guidance values (HBM-GVs) derived for bisphenol A

2021 ◽  
Vol 154 ◽  
pp. 106563
Author(s):  
Eva Ougier ◽  
Florence Zeman ◽  
Jean-Philippe Antignac ◽  
Christophe Rousselle ◽  
Rosa Lange ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Human Biomonitoring
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