scholarly journals Target-Induced Aggregation of Gold Nanoparticles for Colorimetric Detection of Bisphenol A

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Sung Hyun Hwang ◽  
Sehan Jeong ◽  
Hyung Joo Choi ◽  
Hyunmin Eun ◽  
Min Geun Jo ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Bisphenol A ◽  
Tap Water ◽  
Colorimetric Detection ◽  
Daily Intake ◽  
Consumer Products ◽  
Dna Aptamer ◽  
Site Quality ◽  
Local Market ◽  
Induced Aggregation

Bisphenol A (BPA) is used in a wide variety of consumer products owing to its beneficial properties of optical clarity, shatter resistance, and heat resistance. However, leached BPA has been shown to disturb the endocrine system and could cause cancer even at low concentrations, which has led to public concern. To reduce the toxic effects caused by BPA, it is important to monitor the BPA levels and its presence in products in a simple, rapid, and on-site manner. Here, we propose a new colorimetric strategy for the simple and rapid detection of BPA employing a DNA aptamer, a cationic surfactant, and gold nanoparticles (AuNPs). Using the developed system, the presence of BPA can be successfully determined based simply on a visually detectable color change from red to blue, triggered by aggregate formation of the AuNPs, which can be monitored even with the naked eye. Under the optimized conditions, this system could detect BPA with excellent selectivity and sensitivity, and its high performance was validated in the receipt obtained from local market and BPA-spiked tap water samples, ensuring its practical applicability. Moreover, the limit of the detection of the system was determined to be 97 nM, which is below the current tolerable daily intake level, demonstrating its suitability for toxicity assessment and on-site quality control in a more economical manner when compared with conventional methods.

Colorimetric aptasensor for detecting Salmonella spp., Listeria monocytogenes, and Escherichia coli in meat samples

2020 ◽  
Vol 26 (5) ◽  
pp. 430-443 ◽  
Author(s):  
Sudarat Ledlod ◽  
Supatra Areekit ◽  
Somchai Santiwatanakul ◽  
Kosum Chansiri
Keyword(s):  
Escherichia Coli ◽  
Gold Nanoparticles ◽  
Listeria Monocytogenes ◽  
Colorimetric Detection ◽  
Simultaneous Detection ◽  
Dna Aptamer ◽  
Local Market ◽  
Salmonella Spp ◽  
Meat Samples ◽  
Colorimetric Aptasensor

In this study, we successfully developed a simple and rapid method for simultaneous detection of Salmonella spp., Listeria monocytogenes, and Escherichia coli using gold nanoparticles and the aptamer aptasensor. We screened 25 specific DNA aptamer candidates against these pathogens using whole-cell Systematic Evolution of Ligands by EXponential enrichment. Among them, Ap6 was selected due to its low energy minimization values of −12.25 and −27.67 kcal/mol derived from MFold and RNAFold analysis, respectively. The assay presented in this study allowed the visual colorimetric detection of labeled colloidal gold nanoparticles as well as determination of UV absorbance at 625 and 525 nm under optimized conditions. The detection limit of this aptasensor was as less as 105 CFU/ml. A random investigation of 50 meat samples, including ham and chicken sausages, collected from the local market revealed 96% accuracy, 96% specificity, and 100% sensitivity of the assay. The colorimetric aptasensor can accomplish one-step detection without pre-culture, DNA extraction, and amplification. Hence, it is an easy, rapid, specific, and qualitative assay that can be used as a point-of-care testing to directly detect multiplex foodborne pathogens.

Selection of a DNA aptamer for cadmium detection based on cationic polymer mediated aggregation of gold nanoparticles

The Analyst ◽  
2014 ◽  
Vol 139 (6) ◽  
pp. 1550-1561 ◽  
Author(s):  
Yuangen Wu ◽  
Shenshan Zhan ◽  
Lumei Wang ◽  
Pei Zhou
Keyword(s):  
Gold Nanoparticles ◽  
Colorimetric Detection ◽  
Cationic Polymer ◽  
Dna Aptamer ◽  
Recognition Element ◽  
Cadmium Detection ◽  
Selection Of

The DNA aptamer toward cadmium was selected by a novel SELEX strategy and further considered as a recognition element for the colorimetric detection of Cd(ii).

Chitosan-functionalized gold nanoparticles for colorimetric detection of mercury ions based on chelation-induced aggregation

2014 ◽  
Vol 182 (3-4) ◽  
pp. 611-616 ◽  
Author(s):  
Zhengbo Chen ◽  
Chenmeng Zhang ◽  
Yuan Tan ◽  
Tianhui Zhou ◽  
He Ma ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Colorimetric Detection ◽  
Mercury Ions ◽  
Functionalized Gold Nanoparticles ◽  
Induced Aggregation

Colorimetric detection of bisphenol A based on unmodified aptamer and cationic polymer aggregated gold nanoparticles

2016 ◽  
Vol 499 ◽  
pp. 51-56 ◽  
Author(s):  
Dongwei Zhang ◽  
Jiayi Yang ◽  
Jing Ye ◽  
Lurong Xu ◽  
Hanchu Xu ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Bisphenol A ◽  
Colorimetric Detection ◽  
Cationic Polymer

scholarly journals Rapid and visual readout of vitamin B1 based on the electrostatic interaction induced aggregation of gold nanoparticles

RSC Advances ◽  
2018 ◽  
Vol 8 (62) ◽  
pp. 35850-35854
Author(s):  
Liping Lin ◽  
Jiajing Wang ◽  
Wei Liu ◽  
Yaxin Luo ◽  
Yanling Xiao ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Electrostatic Interaction ◽  
Colorimetric Detection ◽  
Vitamin B1 ◽  
Induced Aggregation

Schematic illustration for colorimetric detection of VB1 with AuNPs based on the electrostatic interaction.

scholarly journals Formononetin in Radix Hedysari extract-mediated green synthesis of gold nanoparticles for colorimetric detection of ferrous ions in tap water

RSC Advances ◽  
2020 ◽  
Vol 10 (54) ◽  
pp. 32897-32905
Author(s):  
Xinyue Chen ◽  
Jiahui Ji ◽  
Gengen Shi ◽  
Zhiyuan Xue ◽  
Xianglin Zhou ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Green Synthesis ◽  
Tap Water ◽  
Colorimetric Detection ◽  
Selective Detection ◽  
Ferrous Ions

AuNPs were synthesized using Radix Hedysari extract and used for the sensitive and selective detection of Fe2+.

scholarly journals Incorporating potable water sources and use habits into surveys that improve surrogate exposure estimates for water contaminants: the case of bisphenol A

2013 ◽  
Vol 12 (1) ◽  
pp. 81-93 ◽  
Author(s):  
Syam S. Andra ◽  
Konstantinos C. Makris
Keyword(s):  
Bisphenol A ◽  
Water Consumption ◽  
Tap Water ◽  
Daily Intake ◽  
Human Biomonitoring ◽  
Water Sources ◽  
Water Contact ◽  
Water Contaminants ◽  
Contact Materials ◽  
Consumption Rates

Human biomonitoring studies for water contaminants are often accompanied by surveys relying solely on total drinking water consumption rates, thus, failing to account for specific water sources (bottled and tap water) and use habits, such as water used for preparing cold/hot beverages (coffee, tea, juice, etc.). Despite the extensive use of bisphenol A (BPA) in polycarbonate (PC)-based water contact materials, rarely do BPA biomonitoring studies focus on various PC water uses and sources. Better resolved water consumption rates could reduce the uncertainty associated with surrogate daily BPA intake estimates using fine-tuned surveys. This approach provided a proof of concept on inclusion of water consumption from various sources and uses into estimates of daily intake for water contaminants like BPA found in water-contact materials. The next steps would be in quantifying the extent of improvement in exposure assessment that adds value to refined survey designs.

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