scholarly journals Analyses of protein corona on bare and silica-coated gold nanorods against four mammalian cells

2015 ◽  
pp. 1521 ◽  
Author(s):  
Seong Soo A. An ◽  
Dong Kee Yi ◽  
Minakshi Das
Keyword(s):  
Gold Nanorods ◽  
Protein Corona

Protein Corona around Gold Nanorods as a Drug Carrier for Multimodal Cancer Therapy

2017 ◽  
Vol 3 (6) ◽  
pp. 1039-1050 ◽  
Author(s):  
Eugenia Li Ling Yeo ◽  
Joshua U-Jin Cheah ◽  
Bing Yi Lim ◽  
Patricia Soo Ping Thong ◽  
Khee Chee Soo ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Gold Nanorods ◽  
Drug Carrier ◽  
Protein Corona

Time evolution and dynamic cellular uptake of PEGYlated gold nanorods

RSC Advances ◽  
2016 ◽  
Vol 6 (10) ◽  
pp. 8089-8092 ◽  
Author(s):  
Hongyuan Song ◽  
Qingqiang Xu ◽  
Hongwei Di ◽  
Ting Guo ◽  
Zhongtian Qi ◽  
...  
Keyword(s):  
Time Evolution ◽  
Cellular Uptake ◽  
Gold Nanorods ◽  
Protein Corona

The protein corona formed and evolved of PEGYlated GNRs which alter GNRs characteristics significantly leading to dynamic cellular uptake pathways.

Light-independent M1 macrophage polarization by photosensitizer-loaded protein corona on gold nanorods

Nanomedicine ◽  
2020 ◽  
Vol 15 (24) ◽  
pp. 2329-2344
Author(s):  
Joshua U-Jin Cheah ◽  
Heng Boon Low ◽  
Yongliang Zhang ◽  
James Chen Yong Kah
Keyword(s):  
Protein Expression ◽  
Cell Viability ◽  
Gold Nanorods ◽  
Inductively Coupled Plasma ◽  
Macrophage Polarization ◽  
Protein Corona ◽  
Cell Viability Assay ◽  
M1 Polarization ◽  
M1 Macrophage ◽  
Gene And Protein Expression

Aim: To establish a light-independent functionality of gold nanorods (AuNRs) with a human serum (HS) protein corona loaded with photosensitizer Chlorin e6 (AuNR-HS-Ce6) in M1 polarization of macrophages. Methods: RT-qPCR and ELISA were used to determine gene and protein expression, respectively. Uptake of AuNR-HS-Ce6 was determined via flow cytometry, inductively coupled plasma mass spectrometry and fluorescence microscopy. Cell viability was determined using PrestoBlue® cell viability assay. Results: An increase in M1 gene and protein expression was observed in AuNR-HS-Ce6-treated macrophages. Delivery of high Ce6 payload via AuNR-HS-Ce6 was the primary contributor toward M1 polarization. Finally, DLD-1 cells treated with conditioned media from AuNR-HS-Ce6-treated macrophages showed significantly reduced proliferation. Conclusion: Our study suggests an immunomodulatory potential of Ce6 in inducing light-independent M1 polarization outside of its role as a photosensitizer.

Protein corona influences liver accumulation and hepatotoxicity of gold nanorods

NanoImpact ◽  
2016 ◽  
Vol 3-4 ◽  
pp. 40-46 ◽  
Author(s):  
Huatang Cai ◽  
Yuhui Ma ◽  
Ziran Wu ◽  
Yayun Ding ◽  
Peng Zhang ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Protein Corona

Gold Nanorods Coated with Apolipoprotein E Protein Corona for Drug Delivery

2019 ◽  
Vol 2 (10) ◽  
pp. 6220-6229 ◽  
Author(s):  
Eugenia Li Ling Yeo ◽  
Joshua U-Jin Cheah ◽  
Patricia Soo Ping Thong ◽  
Khee Chee Soo ◽  
James Chen Yong Kah
Keyword(s):  
Drug Delivery ◽  
Apolipoprotein E ◽  
Gold Nanorods ◽  
Protein Corona ◽  
E Protein

scholarly journals Exploiting the protein corona around gold nanorods for low-dose combined photothermal and photodynamic therapy

2017 ◽  
Vol 5 (2) ◽  
pp. 254-268 ◽  
Author(s):  
Eugenia Li Ling Yeo ◽  
Joshua U-Jin Cheah ◽  
Dawn Jing Hui Neo ◽  
Wah Ing Goh ◽  
Pakorn Kanchanawong ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Laser Irradiation ◽  
Gold Nanorods ◽  
Therapeutic Efficacy ◽  
Low Dose ◽  
Protein Corona

We load Ce6 onto NRs using its protein corona, deliver them to cells before performing laser irradiation for simultaneous PTT and PDT with greatly enhanced therapeutic efficacy.

Exploiting the Protein Corona around Gold Nanorods for Loading and Triggered Release

ACS Nano ◽  
2012 ◽  
Vol 6 (8) ◽  
pp. 6730-6740 ◽  
Author(s):  
James Chen Yong Kah ◽  
John Chen ◽  
Angel Zubieta ◽  
Kimberly Hamad-Schifferli
Keyword(s):  
Gold Nanorods ◽  
Protein Corona ◽  
Triggered Release

Synthesis and Characterization of Polydopamine-Coated Gold Nanorods

2017 ◽  
Vol 62 (1-2) ◽  
pp. 23-31
Author(s):  
L.C. Şuşu ◽  
◽  
A.M. Crăciun ◽  
S. Aştilean ◽  
◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Synthesis And Characterization
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