scholarly journals Some Trends in the Somatic Development of Children and Adolescents under Iodine-deficiency: Materials from the Saratov Region

2005 ◽  
Vol 24 (4) ◽  
pp. 313-319 ◽  
Author(s):  
Elena Z. Godina ◽  
Irena A. Khomyakova ◽  
Arsen L. Purundjan ◽  
Ludmila V. Zadorozhnaya ◽  
Alevtina V. Stepanova
Keyword(s):  
Children And Adolescents ◽  
Iodine Deficiency ◽  
Saratov Region ◽  
Somatic Development

Impairment of neuromotor and cognitive development in iodine-deficient schoolchildren with normal physical growth

1993 ◽  
Vol 129 (6) ◽  
pp. 501-504 ◽  
Author(s):  
F Azizi ◽  
A Sarshar ◽  
M Nafarabadi ◽  
A Ghazi ◽  
M Kimiagar ◽  
...  
Keyword(s):  
Cognitive Development ◽  
Children And Adolescents ◽  
Thyroid Function ◽  
Iodine Deficiency ◽  
Endemic Goiter ◽  
Physical Growth ◽  
Psychomotor Development ◽  
Somatic Development ◽  
Intellectual Quotient ◽  
The Mean

In order to detect somatic and psychomotor disturbances in children and adolescents residing in areas of iodine deficiency, schoolchildren from three areas with different degrees of iodine deficiency were studied. In Randan, the prevalence of severe endemic goiter was accompanied by alteration in thyroid function, increased thyrotropin levels and retardation of both bone and psychomotor age and decreased intellectual quotient. In Tehran, where iodine deficiency is mild, visible goiter was present in 1 5% of schoolchildren but no alterations in thyroid function, serum thyrotropin, somatic or psychomotor development could be detected. In Zagoon, where the prevalence and severity of goiter was less than Randan but more than Tehran, thyroid function was normal but slightly decreased as compared to Tehran; somatic development was unaltered, but retardation in psychomotor development was evident and the mean intellectual quotient was less than that of Tehranian schoolchildren. These findings indicate the occurrence of physical and psychomotor disturbances in apparently normal schoolchildren from areas of iodine deficiency. Alteration in psychomotor development may occur in children with normal physical growth, due to iodine deficiency.

Iodine deficiency diseases in children and adolescents (plenary lecture)

2019 ◽  
Vol 43 (3) ◽  
pp. 3-7 ◽  
Author(s):  
E. P. Kasatkina
Keyword(s):  
Thyroid Gland ◽  
Adverse Effects ◽  
Children And Adolescents ◽  
Human Health ◽  
Iodine Deficiency ◽  
Functional Activity ◽  
Endemic Goiter ◽  
Plenary Lecture ◽  
Long Time ◽  
Deficiency Diseases

The main consequence of iodine deficiency in the environment is the development of goiter in people living in iodine-deficient regions (endemic goiter). In this regard, for a long time it was considered that goiter is the only manifestation of this condition. It has now been proven that, in addition to goiter, iodine deficiency also has other adverse effects on human health. In 1983, the term "endemic goiter" was replaced by the term  "iodine deficiency diseases" (IDD). These diseases are caused by a decrease in the functional activity of the thyroid gland in response to iodine deficiency.

scholarly journals Iodine deficiency among Italian children and adolescents assessed through 24-hour urinary iodine excretion

2019 ◽  
Vol 109 (4) ◽  
pp. 1080-1087 ◽  
Author(s):  
Angelo Campanozzi ◽  
Irene Rutigliano ◽  
Paolo E Macchia ◽  
Gianpaolo De Filippo ◽  
Antonio Barbato ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Iodine Deficiency ◽  
Urinary Iodine ◽  
Iodine Intake ◽  
Urinary Iodine Excretion ◽  
Urinary Iodine Concentration ◽  
Age Related ◽  
Italian Regions ◽  
Significant Difference ◽  
Iodine Excretion

ABSTRACTBackgroundIodine is an essential micronutrient for intellectual development in children. Information on iodine intakes based on 24-h urinary iodine excretion (UIE) is scant, because iodine status is only assessed by the measurement of urinary iodine concentration (UIC) in spot urine samples.ObjectivesThe aim of our study was to evaluate the iodine intake of school-age children and adolescents, using UIE measurement in 24-h urine collections.MethodsThe study population included 1270 healthy subjects (677 boys, 593 girls) aged 6–18 y (mean age ± SD: 10.3 ± 2.9) from 10 Italian regions. Daily iodine intake was estimated as UIE/0.92, based on the notion that $\sim$92% of the dietary iodine intake is absorbed. The adequacy of intakes was assessed according to the Dietary Reference Values for iodine of the European Food Safety Authority (EFSA). Body mass index (BMI) and UIC were also measured for each subject.ResultsBased on the scientific opinion of EFSA, 600 of 1270 subjects (47.2%) had a lower than adequate iodine intake, with a higher prevalence among girls (54.6%) compared with boys (40.2%) (P < 0.001). Although UIE and 24-h urinary volumes increased with age (P < 0.001), a progressive decrease in the percentage of subjects with iodine excretion <100 µg/24 h (P < 0.001) was observed, without any significant difference in the percentage of subjects with UIC <100 µg/L. No significant association was detected between BMI z-score and UIE (P = 0.603) or UIC (P = 0.869).ConclusionsA sizable proportion of our population, especially girls, appeared to be at risk of iodine inadequacy. The simple measurement of UIC could lead to underestimation of the occurrence of iodine deficiency in younger children, because of the age-related smaller urine volumes producing spuriously higher iodine concentrations.

scholarly journals Assessment of the efficiency of prevention of iodine deficiency among the children’s population of the city of Mezhdurechensk of the Kemerovo region

2019 ◽  
Vol 95 (5) ◽  
pp. 471-476 ◽  
Author(s):  
Nataliya V. Tapeshkina ◽  
A. Ya. Perevalov
Keyword(s):  
Comparative Analysis ◽  
Children And Adolescents ◽  
Iodine Deficiency ◽  
School Children ◽  
Iodized Salt ◽  
Urine Samples ◽  
Mild Deficiency ◽  
The City ◽  
Positive Results

In the article there are presented results of a study of indices of ioduria in preschool kids and school children of the city of Mezhdurechensk (south of the Kemerovo region). 411 children aged of 3-17 years participated in the study. The median of ioduria on preschooler kids was 97,0 pg/l, and the proportion of urine samples with iodine levels less than 50 pg/l - 1,0%. The median of ioduria in school children is 98,0 pg/l, the percentage of urine samples with iodine levels less than 50 pg/l accounts for 1,3%. On average, on the population of children there was established that the percentage of urine samples with iodine levels from 50-100 pg/l (mild deficiency) was detected in 53,5% of children. Comparative analysis of indices of the level of ioduria according to data obtained in 2008 and 2014 in a group of school children showed that the measures taken to prevent diseases caused by iodine deficiency (the use of iodized salt in the diet of children and adolescents from organized groups on a regular basis) have given positive results.

scholarly journals Radiation-induced pathomorphism of endemic goiter in children and adolescents in a focus of iodine deficiency (initial manifestations of remore effects of the Chernobyl accident)

1995 ◽  
Vol 41 (3) ◽  
pp. 17-23 ◽  
Author(s):  
E. P. Kasatkina ◽  
D. Ye. Shilin ◽  
A. N. Matkovskaya ◽  
K N. Sokolovskaya ◽  
T. N. Volkova ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Iodine Deficiency ◽  
Chernobyl Accident ◽  
Radiation Effects ◽  
Low Dose ◽  
Endemic Goiter ◽  
Morphological Characteristics ◽  
Increased Risk ◽  
Diffuse Goiter ◽  
Progressive Growth

The formation of remote consequences of radiation effects on the thyroid status of the population exposed to low-dose radiation was studied. The authors analyzed epidemiological, clinical, biochemical, hormonal, ultrasonographic, immunological, and morphological characteristics of the prevalence and intensity of endemic goiter in children and adolescents living in two iodine-deficient districts of the Oryol region observed after contamination of their territory with 137-Cs in a dose of 1 to 5 Ci/km2 and in-corporation of 131-I in a dose of 20-30 rad and in a control district free from radiation contamination. The results indicate that under the effect of low-dose combined irradiation endemic goiter in the observed districts acquired atypical features in the six years that passed since the Chernobyl accident in comparison with that in the control region: 1) thyromegalia prevalence is increased, its level being disproportionate with the degree of the existent iodine deficiency; 2) sex-specific differences are completely absent; 3) the maximal strain is observed in children exposed to radioactive iodine in utero 4) morphologically, variants of diffuse goiter with a high risk of node formation predominate; 5) progressive growth of thyroid parenchyma is associated with increased thyroglobulin elimination, this increasing the strain of the humoral component of antithyroid autoimmunity. These data indicate that the modifying effect of low-dose exposure on endemic goiter resulted in the disease pathomorphism associated with oncological risk and increased risk of autoimmune thyroiditis.

scholarly journals Tuberculosis situation among the pediatric population of Saratov Region (2015-2019)

2022 ◽  
Vol 99 (12) ◽  
pp. 33-37
Author(s):  
E. N. Aleksandrova ◽  
T. I. Morozova ◽  
T. Yu. Salina
Keyword(s):  
Children And Adolescents ◽  
Population Analysis ◽  
Pediatric Population ◽  
Recombinant Allergen ◽  
Tuberculosis Screening ◽  
Group Vi ◽  
Saratov Region ◽  
Number Of Children ◽  
Group Iva ◽  
Tuberculosis In Children

Subjects and Methods. Incidence and prevalence of tuberculosis among children and adolescents in Saratov Region were retrospectively analyzed for 2015-2019.Results. The incidence of tuberculosis in children reflects general trends in the epidemic situation over the years in Saratov Region. In this region during 10 years of monitoring, tuberculosis incidence among children decreased 4 times by 2019 and it made 2.3 per 100,000 population, and among adolescents, it decreased 1.6 times (16.3 per 100,000 population). The number of children with post-tuberculosis changes detected for the first time increased 3 times in 2019 versus 2015, and the number of adolescents increased 4.5 times not only due to transition to tuberculosis screening in children aged 8-17 years old by skin test with tuberculosis recombinant allergen but also to the examination of children by computed tomography. The incidence in children followed up as Group IVA in 2019 was 15 times higher than this rate in the overall pediatric population. Analysis of the number of children and adolescents who developed tuberculosis and followed up as Groups IV and VI in 2015-2019 showed that the number of children ill with tuberculosis in Group IV was 3 times higher than the number of children in Group VI.

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