scholarly journals The effects of graded levels of calorie restriction: VIII. Impact of short term calorie and protein restriction on basal metabolic rate in the C57BL/6 mouse

Oncotarget ◽  
2017 ◽  
Vol 8 (11) ◽  
pp. 17453-17474 ◽  
Author(s):  
Sharon E. Mitchell ◽  
ZhanHui Tang ◽  
Celine Kerbois ◽  
Camille Delville ◽  
Davina Derous ◽  
...  
Keyword(s):  
Metabolic Rate ◽  
Calorie Restriction ◽  
Basal Metabolic Rate ◽  
Protein Restriction ◽  
Short Term

scholarly journals The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse

Oncotarget ◽  
2016 ◽  
Vol 7 (15) ◽  
pp. 19147-19170 ◽  
Author(s):  
Sharon E. Mitchell ◽  
Camille Delville ◽  
Penelope Konstantopedos ◽  
Davina Derous ◽  
Cara L. Green ◽  
...  
Keyword(s):  
Physical Activity ◽  
Calorie Restriction ◽  
Protein Restriction ◽  
Short Term

Thermal history can affect the short-term thermal acclimation of basal metabolic rate in the passerine Zonotrichia capensis

2009 ◽  
Vol 34 (8) ◽  
pp. 415-419 ◽  
Author(s):  
Gonzalo Barceló ◽  
Jonathan Salinas ◽  
Grisel Cavieres ◽  
Mauricio Canals ◽  
Pablo Sabat
Keyword(s):  
Metabolic Rate ◽  
Basal Metabolic Rate ◽  
Thermal History ◽  
Thermal Acclimation ◽  
Short Term ◽  
Zonotrichia Capensis

scholarly journals The effects of graded levels of calorie restriction: I. impact of short term calorie and protein restriction on body composition in the C57BL/6 mouse

Oncotarget ◽  
2015 ◽  
Vol 6 (18) ◽  
pp. 15902-15930 ◽  
Author(s):  
Sharon E. Mitchell ◽  
Zhanhui Tang ◽  
Celine Kerbois ◽  
Camille Delville ◽  
Penelope Konstantopedos ◽  
...  
Keyword(s):  
Body Composition ◽  
Calorie Restriction ◽  
Protein Restriction ◽  
Short Term

scholarly journals The effects of graded levels of calorie restriction: III. Impact of short term calorie and protein restriction on mean daily body temperature and torpor use in the C57BL/6 mouse

Oncotarget ◽  
2015 ◽  
Vol 6 (21) ◽  
pp. 18314-18337 ◽  
Author(s):  
Sharon E. Mitchell ◽  
Camille Delville ◽  
Penelope Konstantopedos ◽  
Davina Derous ◽  
Cara L. Green ◽  
...  
Keyword(s):  
Body Temperature ◽  
Calorie Restriction ◽  
Protein Restriction ◽  
Short Term

scholarly journals CPAP Effect on Cardiopulmonary Exercise Testing Performance in Patients with Moderate-Severe OSA and Cardiometabolic Comorbidities

Medicina ◽  
2020 ◽  
Vol 56 (2) ◽  
pp. 80 ◽  
Author(s):  
Ioana Mădălina Zota ◽  
Cristian Stătescu ◽  
Radu Andy Sascău ◽  
Mihai Roca ◽  
Radu Sebastian Gavril ◽  
...  
Keyword(s):  
Oxygen Uptake ◽  
Metabolic Rate ◽  
Exercise Testing ◽  
Functional Capacity ◽  
Aerobic Capacity ◽  
Basal Metabolic Rate ◽  
Cardiopulmonary Exercise Testing ◽  
Short Term ◽  
Cardiopulmonary Exercise ◽  
Before And After

Background and Objectives: Obstructive sleep apnea (OSA) is associated with daytime somnolence, cognitive impairment and high cardiovascular morbidity and mortality. Obesity, associated cardiovascular comorbidities, accelerated erythropoiesis and muscular mitochondrial energetic dysfunctions negatively influence exercise tolerance in moderate-severe OSA patients. The cardiopulmonary exercise testing (CPET) offers an integrated assessment of the individual’s aerobic capacity and helps distinguish the main causes of exercise limitation. The purpose of this study is to evaluate the aerobic capacity of OSA patients, before and after short-term continuous positive airway pressure (CPAP). Materials and Methods: Our prospective study included 64 patients with newly diagnosed moderate-severe OSA (apnea hypopnea index (AHI) 39.96 ± 19.04 events/h) who underwent CPET before and after CPAP. Thirteen patients were unable to tolerate CPAP or were lost during follow-up. Results: 49.29% of our patients exhibited a moderate or severe decrease in functional capacity (Weber C or D). CPET performance was influenced by gender but not by apnea severity. Eight weeks of CPAP induced significant improvements in maximal exercise load (Δ = 14.23 W, p = 0.0004), maximum oxygen uptake (Δ = 203.87 mL/min, p = 0.004), anaerobic threshold (Δ = 316.4 mL/min, p = 0.001), minute ventilation (Δ = 5.1 L/min, p = 0.01) and peak oxygen pulse (Δ = 2.46, p = 0.007) as well as a decrease in basal metabolic rate (BMR) (Δ = −8.3 kCal/24 h, p = 0.04) and average Epworth score (Δ = −4.58 points, p < 0.000001). Conclusions: Patients with moderate-severe OSA have mediocre functional capacity. Apnea severity (AHI) was correlated with basal metabolic rate, resting heart rate and percent predicted maximum effort but not with anaerobic threshold or maximum oxygen uptake. Although CPET performance was similar in the two apnea severity subgroups, short-term CPAP therapy significantly improved most CPET parameters, suggesting that OSA per se has a negative influence on effort capacity.

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