scholarly journals Association between different types of plant-based diets and leptin levels in healthy volunteers

2019 ◽  
Author(s):  
Patrycja Gogga ◽  
Aleksandra Śliwińska ◽  
Ewa Aleksandrowicz-Wrona ◽  
Syliwa Małgorzewicz
Keyword(s):  
Fatty Acids ◽  
Body Fat ◽  
Diet Group ◽  
The Body ◽  
Vegan Diet ◽  
Omega 3 ◽  
Dietary Recall ◽  
Total Carbohydrates ◽  
Total Fat ◽  
Plasma Leptin

Leptin is an important factor regulating appetite and energety metabolism; disturbances in its signaling are related to adiposity and contribute to the excessive body fat. About a third of the human population is overweight or suffers from obesity, as well as from associated medical conditions. It is well established that vegetarian, especially vegan, diet is very effective in lowering BMI and body fat, thus, plant-based diets are associated with a lower risk of obesity. The aim of this study was to evaluate the plasma levels of leptin in lacto-ovo-vegetarian and vegan volunteers with normal BMI. The intake of energy and selected diet components such as polyunsaturated fatty acids (PUFA) and carbohydrates was also investigated. The study involved healthy women – 14 omnivores, 17 lacto-ovo-vegetarians, and 11 vegans. All women had a normal BMI (18.5-24.99). The plasma leptin levels were examined with immunoenzymatic test (ELISA). All participants were interviewed to estimate their nutrient intake by performing a 24-hour dietary recall. Both lacto-ovo-vegetarians and vegans had lower plasma leptin concentrations than their meat-consuming counterparts. Every analyzed diet group had a different body fat content, with the highest level in omnivores and the lowest in vegans. All participants had similar calorie, total fat, and total carbohydrates intake. Total PUFA and specifically omega-3 fatty acids consumption was lower in omnivores when compared to both types of plant diet; the same was found for fiber intake. Our results suggest that adopting a plant-based diet may be beneficial for energetic metabolism, as it significantly lowers the body fat storage and circulating leptin levels.

DEVELOPMENT OF AN EXPERIMENTAL MODEL OF AVITAMINOSIS F

2020 ◽  
Vol 20 (2) ◽  
pp. 38-40
Author(s):  
A. Levitsky ◽  
A. Lapinska ◽  
I. Selivanskaya
Keyword(s):  
Fatty Acids ◽  
Experimental Model ◽  
Unsaturated Fatty Acids ◽  
Saturated Fatty Acids ◽  
Coconut Oil ◽  
The Body ◽  
Regulatory Function ◽  
Omega 3 ◽  
White Rats ◽  
Arachidonic Acids

The article analyzes the role of essential polyunsaturated fatty acids (PUFA), especially omega-3 series in humans and animals. The biosynthesis of essential PUFA in humans and animals is very limited, so they must be consumed with food (feed). Тhe ratio of omega-3 and omega-6 PUFA is very important. Biomembranes of animal cells contain about 30% PUFA with a ratio of ω-6/ ω-3 1-2. As this ratio increases, the physicochemical properties of biomembranes and the functional activity of their receptors change. The regulatory function of essential PUFA is that in the body under the action of oxygenase enzymes (cyclooxygenase, lipoxygenase) are formed extremely active hormone-like substances (eicosanoids and docosanoids), which affect a number of physiological processes: inflammation, immunity, metabolism. Moreover, ω-6 PUFA form eicosanoids, which have pro-inflammatory, immunosuppressive properties, and ω-3 PUFAs form eicosanoids and docosanoids, which have anti-inflammatory and immunostimulatory properties. Deficiency of essential PUFA, and especially ω-3 PUFA, leads to impaired development of the body and its state of health, which are manifestations of avitaminosis F. Prevention and treatment of avitaminosis F is carried out with drugs that contain PUFA. To create new, more effective vitamin F preparations, it is necessary to reproduce the model of vitamin F deficiency. An experimental model of vitamin F deficiency in white rats kept on a fat –free diet with the addition of coconut oil, which is almost completely free of unsaturated fatty acids, and saturated fatty acids make up almost 99 % of all fatty acids was developed. The total content of ω-6 PUFA (sum of linoleic and arachidonic acids), the content of ω-3 PUFA (α-linolenic, eicosapentaenoic and docosahexaenoic acids) in neutral lipids (triglycerides and cholesterol esters) defined. Тhe content of ω-6 PUFA under the influence of coconut oil decreased by 3.3 times, and the content of ω-3 PUFA - by 7.5 times. Тhe influence of coconut oil, the content of ω-6 PUFA decreased by 2.1 times, and the content of ω-3 PUFA - by 2.8 times. The most strongly reduces the content of ω-3 PUFA, namely eicosapentaenoic, coconut oil, starting from 5 %. Consumption of FFD with a content of 15 % coconut oil reduces the content of eicosapentaenoic acid to zero, ie we have an absolute deficiency of one of the most important essential PUFAs, which determined the presence of vitamin F deficiency.

EFFECTS OF DIET ON THE COMPOSITION OF BODY FAT IN AGRIA AFFINIS (FALLÉN)

1965 ◽  
Vol 43 (2) ◽  
pp. 337-340 ◽  
Author(s):  
J. S. Barlow
Keyword(s):  
Fatty Acids ◽  
Oleic Acid ◽  
Fatty Acid ◽  
Body Fat ◽  
Acid Content ◽  
Palmitoleic Acid ◽  
The Body ◽  
Nutritional Adequacy

When larvae of the parasitic fly Agria affinis (Fallén) were reared on fatty acid free diets, the characteristically high palmitoleic acid content of the body fats was much increased. Oleic acid in the diet was effective in reducing this, but not so effective as a mixture of fatty acids. The body fats still contained unusually high proportions of palmitic, palmitoleic, and oleic acids even when a mixture of fatty acids was fed. These observations are related to earlier observations on the nutritional adequacy of various fatty acids.

scholarly journals Electroacupuncture Reduces Weight in Diet-Induced Obese Rats via Hypothalamic Tsc1 Promoter Demethylation and Inhibition of the Activity of mTORC1 Signaling Pathway

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Jincheng Leng ◽  
Feng Xiong ◽  
Junpeng Yao ◽  
Xiahuan Dai ◽  
Yulei Luo ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Body Fat ◽  
Mammalian Target Of Rapamycin ◽  
Gene Promoter ◽  
Chow Group ◽  
Diet Group ◽  
The Body ◽  
Sprague Dawley ◽  
Tsc1 Gene ◽  
Mtorc1 Signaling

Subject. The study aimed to investigate the mechanism of electroacupuncture reducing weight via tuberous sclerosis complex 1 (Tsc1) promoter methylation, inhibiting the mammalian target of rapamycin complex 1 (mTORC1) pathway. Materials and Methods. Male Sprague-Dawley rats were divided into chow-fed group (chow group) or high-fat diet group (HF group) for 14 weeks. The obesity rats in HF group were randomly divided into electroacupuncture group (EA group) and diet-induced obesity (DIO) group, which received EA stimulation on bilateral ST25, RN12, SP6, and ST36 for 4 weeks or no further treatment, respectively. Methylation of the Tsc1 gene promoter and expression of agouti-related protein (AgRP), neuropeptide Y (NPY), and proopiomelanocortin (PoMC) were detected at the 18th week. Results. At week 18, weight, body fat, and the body fat rate in DIO group were significantly higher than those of the chow and EA group. Compared with the chow group, the DIO group had increased methylation of the Tsc1 gene promoter and expression of mTORC1, AgRP, and NPY gene and decreased PoMC in the hypothalamus; after EA, methylation of the Tsc1 gene promoter, mRNA, and protein of the mTORC1 and expression of AgRP and NPY gene decreased and PoMC increased significantly. Conclusions. Our study could shed light on the potential pathway where EA exerts effects on the mechanism of EA treatment for obesity through the hypothalamic Tsc1 promoter demethylation and inhibition of the activity of mTORC1 signaling pathway.

scholarly journals PENGARUH PADAT TEBAR TERHADAP KANDUNGAN ZAT GIZI IKAN LELE YANG DIPELIHARA DENGAN TEKNOLOGI BIOFLOK

2019 ◽  
Vol 20 (2) ◽  
pp. 120-131
Author(s):  
Settings Anang Suhardianto ◽  
Ariyanti Hartari
Keyword(s):  
Fatty Acids ◽  
Confidence Interval ◽  
Water Content ◽  
Unsaturated Fatty Acids ◽  
Statistical Tests ◽  
Stocking Density ◽  
Nutrient Content ◽  
Omega 3 ◽  
Omega 6 ◽  
Total Fat

This study aims to determine the effect of stocking density on the nutrient content of catfish that is maintained with biofloc technology. Nutrients observed: 1) water content, 2) protein, 3) carbohydrates, 4) total fat, 5) saturated fatty acids / SFA, 6) monounsaturated fatty acids/ MUFA, 7) plural unsaturated fatty acids / PUFA , 8) omega-3, 9) omega-6, and 10) omega 9. Statistical tests on the 10 variables showed that stocking density did not have a significant effect on the 10 variables at a 5% confidence interval. Stocking density of treatment is 1000 heads/pond (T1), 2000 heads/pond (T2), 3000 heads/pond (T3), with a pond size of 2.0 m x height 1.0 m. Research results: 1. The average water content is 69.40–71.47% and the highest T3. 2. The protein content is 14.70-15.90%, the highest T2. 3. Carbohydrate content of 5.16-5.50%, the highest T2. 4. The average total fat content of 6.73-7.78%, the highest T1. 5. SFA content is around 43%, PUFA around 23%, and MUFA around 32%. 6. The highest omega-3 content is T3, then T1, and T2. Omega-6 and 9 sequence contents are T1, T2, and T3. It was concluded, the treatment of biofloc catfish stocking densities at a 5% confidence interval did not have a significant effect on the specified nutrient content. Penelitian ini bertujuan untuk menentukan pengaruh padat tebar terhadap kandungan zat gizi ikan lele yang dipelihara dengan teknologi bioflok. Zat gizi yang diamati: 1) kandungan air, 2) protein, 3) karbohidrat, 4) lemak total, 5) asam lemak jenuh/SFA, 6) asam lemak tak jenuh tunggal/MUFA, 7) asam lemak tak jenuh jamak/PUFA, 8) omega-3, 9) omega 6, dan 10) omega 9. Uji statistik terhadap ke-10 variabel menunjukkan padat tebar tidak memberikan pengaruh nyata terhadap ke-10 variabel pada selang kepercayaan 5%.  Padat tebar perlakuan adalah 1000 ekor/kolam (T1),  2000 ekor/kolam (T2), 3000 ekor/kolam (T3), dengan ukuran kolam diameter 2,0 m x tinggi 1,0 m. Hasil penelitian: 1. Rata-rata kandungan air 69,40–71,47% dan T3 tertinggi. 2. Kandungan protein 14,70–15,90%, T2 tertinggi. 3. Kandungan karbohidrat 5,16–5,50%, T2 tertinggi. 4. Rata-rata kandungan lemak total 6,73–7,98%, T1 tertinggi. 5. Kandungan SFA sekitar 43%, PUFA sekitar 23%, dan MUFA sekitar 32%. 6. Kandungan omega-3 tertinggi T3, kemudian T1, dan T2. Omega-6 dan 9 urutan kandungannya T1, T2, dan T3.  Disimpulkan, perlakuan padat tebar lele bioflok pada selang kepercayaan 5% tidak memberikan pengaruh yang nyata terhadap kandungan zat gizi yang ditentukan.

scholarly journals HUBUNGAN KONSUMSI ASAM LEMAK OMEGA-3, AKTIVITAS FISIK DAN PERSEN LEMAK TUBUH DENGAN TINGKAT DISMENORE PADA REMAJA

2017 ◽  
Vol 6 (4) ◽  
pp. 268
Author(s):  
Famimah Famimah ◽  
Ani Margawati ◽  
Deny Yudi Fitranti
Keyword(s):  
Physical Activity ◽  
Fatty Acids ◽  
Body Fat ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Percent Body Fat ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Cross Sectional

Background: Dysmenorrhea or menstrual pain was a gynecological complaint due to an imbalance of progesterone in the blood resulting in pain. A woman with dysmenorrhea should consume food rich in omega-3 fatty acids such as fish oil, fish (salmon, tuna, mackerel, herring), soybeans and fruits. Low fish consumption was related with severity of dysmenorrhea. In addition, physical activity and percent body fat were also associated with severity of dysmenorrhea.Objective : To determine the correlation between consumption of omega-3 fatty acids, physical activity and percent body fat to the classification of dysmenorrhea in adolescents.Methods : Cross sectional study of 90 adolescentsselected by purposive sampling. This research was conducted in SMA N 15 and SMA N 9 Semarang. Menstrual history was measured by direct interviews and level of dysmenorrhea was measured using Numerical Rating Scale Questionnaire. Omega-3 fatty acids were measured using Food Frequency Questionnaire (FFQ) and analyzed using a nutritional software program. Physical activity was measured using A short questionnaire for the measurement of habitual physical activity in epidemiological studies. Percent body fat was measured using Bioelectrical Impedance Analysis (BIA). Data were analyzed by Independent T test/Mann Whitney. Result : There were significant correlation in omega-3 fatty acid (p= 0,015), and percent body fat (p= 0,026). While in physical activity there was no significant correlation (p= 0,394).Conclusion : Consumption of omega-3 fatty acids and percent body fat were associated with the classification of dysmenorrhea.

The Composition of the Body Fat of Small Green Chironomids

1952 ◽  
Vol 29 (3) ◽  
pp. 440-444
Author(s):  
D. N. GRINDLEY
Keyword(s):  
Fatty Acids ◽  
Body Fat ◽  
Larval Stage ◽  
The Body ◽  
Terrestrial Insects

The body fat of the midge, Tanytarsus lewisi (Chironomidae), has been analysed, and has been found to contain major amounts of polyethenoid fatty acids normally associated with the fat of fish. It is interesting to note that this insect does all its feeding while in the larval stage on the bed of the river, under water, and that the body fat resembles that of algae, and plankton, which probably are the main sources of food, and differs considerably from the composition of most terrestrial insects hitherto recorded.

scholarly journals Omega-3 Polyunsaturated Fatty Acids Inhibit the Function of Human URAT1, a Renal Urate Re-Absorber

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1601 ◽  
Author(s):  
Hiroki Saito ◽  
Yu Toyoda ◽  
Tappei Takada ◽  
Hiroshi Hirata ◽  
Ami Ota-Kontani ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Human Health ◽  
Serum Urate ◽  
The Body ◽  
Omega 3 ◽  
Beneficial Effects ◽  
Uricosuric Agents ◽  
Transport Assay ◽  
The Impact

The beneficial effects of fatty acids (FAs) on human health have attracted widespread interest. However, little is known about the impact of FAs on the handling of urate, the end-product of human purine metabolism, in the body. Increased serum urate levels occur in hyperuricemia, a disease that can lead to gout. In humans, urate filtered by the glomerulus of the kidney is majorly re-absorbed from primary urine into the blood via the urate transporter 1 (URAT1)-mediated pathway. URAT1 inhibition, thus, contributes to decreasing serum urate concentration by increasing net renal urate excretion. Here, we investigated the URAT1-inhibitory effects of 25 FAs that are commonly contained in foods or produced in the body. For this purpose, we conducted an in vitro transport assay using cells transiently expressing URAT1. Our results showed that unsaturated FAs, especially long-chain unsaturated FAs, inhibited URAT1 more strongly than saturated FAs. Among the tested unsaturated FAs, eicosapentaenoic acid, α-linolenic acid, and docosahexaenoic acid exhibited substantial URAT1-inhibitory activities, with half maximal inhibitory concentration values of 6.0, 14.2, and 15.2 μM, respectively. Although further studies are required to investigate whether the ω-3 polyunsaturated FAs can be employed as uricosuric agents, our findings further confirm FAs as nutritionally important substances influencing human health.

scholarly journals Changes in Body Fat Distribution in Antiretroviral-Naive HIV-Positive Individuals Initiating Current ART Regimens

2018 ◽  
Vol 104 (3) ◽  
pp. 900-905 ◽  
Author(s):  
Juan Tiraboschi ◽  
Antonio Navarro-Alcaraz ◽  
Dolors Giralt ◽  
Carmen Gomez-Vaquero ◽  
Maria Saumoy ◽  
...  
Keyword(s):  
Body Mass ◽  
Body Fat ◽  
Fat Mass ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
The Body ◽  
Strand Transfer ◽  
Mass Ratio ◽  
Total Fat ◽  
Fat Mass Ratio

Abstract Objectives To describe the changes in body fat distribution (BFD) occurring over 60 months in a group of antiretroviral therapy (ART)-naive individuals starting different antiretroviral regimens. Methods A prospective ongoing fat change assessment including clinical evaluation and dual X-ray absorptiometry scan is being conducted in all consecutive patients initiating ART from January 2008. Arm, leg, trunk, and total fat as well as fat mass ratio were determined. Results A total of 146 patients were included (80% male, 40% MSM). Mean age was 44 years, HIV-1 RNA was 4.98 log10 copies/mL, and CD4 count was 254 cells/μL. The most common initial antiretroviral combination included non-nucleoside reverse transcription inhibitor (NNRTI) drugs followed by protease inhibitor (PI) and integrase strand transfer inhibitor (INSTI)-based regimens. At month 36, an increase was seen in the body mass index (BMI), total fat, trunk fat, and limb fat. The fat mass ratio (FMR) also showed a significant increase in both men and women (P = 0.001). In patients receiving NNRTI- or INSTI-based regimens (but not PIs), there was a marginal but statistically significant increase in the FMR (0.10 and 0.07, respectively; P = 0.01). Sixty-two subjects completed 60 months of follow-up. FMR showed a significant increase even in the PI group at this time point (P < 0.03). Conclusions We observed a significant increase in the fat and lean body mass in all compartments and treatment groups over 36 and 60 months. Clinically irrelevant differences were found in fat distribution regardless of the treatment group and baseline characteristics. The data suggest that current antiretroviral regimens have little impact on BFD during the first years of treatment.

scholarly journals Omega-3 Fatty Acids for Sport Performance—Are They Equally Beneficial for Athletes and Amateurs? A Narrative Review

Nutrients ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3712
Author(s):  
Frank Thielecke ◽  
Andrew Blannin
Keyword(s):  
Fatty Acids ◽  
Immune Modulation ◽  
Enhanced Recovery ◽  
Sport Performance ◽  
The Body ◽  
Endurance Capacity ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Beneficial Effects ◽  
Clinical Endpoints

Omega-3 fatty acids, specifically eicosapentanoic acid (EPA, 20:5n-3) and docosahexanoic acid (DHA, 22:6n-3) are receiving increasing attention in sports nutrition. While the usual focus is that of athletes, questions remain if the different training status between athletes and amateurs influences the response to EPA/DHA, and as to whether amateurs would benefit from EPA/DHA supplementation. We critically examine the efficacy of EPA/DHA on performance, recovery and injury/reduced risk of illness in athletes as well as amateurs. Relevant studies conducted in amateurs will not only broaden the body of evidence but shed more light on the effects of EPA/DHA in professionally trained vs. amateur populations. Overall, studies of EPA/DHA supplementation in sport performance are few and research designs rather diverse. Several studies suggest a potentially beneficial effect of EPA/DHA on performance by improved endurance capacity and delayed onset of muscle soreness, as well as on markers related to enhanced recovery and immune modulation. The majority of these studies are conducted in amateurs. While the evidence seems to broadly support beneficial effects of EPA/DHA supplementation for athletes and more so in amateurs, strong conclusions and clear recommendations about the use of EPA/DHA supplementation are currently hampered by inconsistent translation into clinical endpoints.

The Use of Crude Fish Oil (CFO) in Vannamei Shrimp (Litopenaeus vannamei) Feed on EPA and DHA Contents

2020 ◽  
Vol 9 (3) ◽  
pp. 232
Author(s):  
Januar Hadi Prasetyo ◽  
Agustono Agustono ◽  
Widya Paramitha Lokapirnasari
Keyword(s):  
Fatty Acids ◽  
Fish Oil ◽  
Essential Fatty Acids ◽  
Penaeid Shrimp ◽  
The Body ◽  
Omega 3 ◽  
Alpha Linolenic Acid ◽  
Epa And Dha ◽  
Randomized Design ◽  
Omega 6

Omega-3 fatty acids (Alpha-linolenic acid) and omega-6 fatty acids (Linoleic acid) are a group of essential fatty acids. Essential fatty acids are fatty acids that cannot be synthesized by the body so that must be supplied from the diet. One of the sources of essential fatty acids is derived from fish oil. This study aims to determine the effect of Crude Fish Oil (CFO) in the feed to EPA and DHA content in penaeid shrimp meat. The research method used was a completely randomized design. The treatments used are the varying content of Crude Fish Oil (CFO), which are P0 (0%), P1 (2%), P2 (4%), P3 (6%), and P4 (8%). The results of the study showed significant differences (p <0.05) on the content of EPA and DHA in penaeid shrimp meat. The highest content of EPA and DHA found in P4 treatment (8%) and the lowest at P0 treatment (0%). The use of CFO in penaeid shrimp feed need further study related to the growth of shrimps and prawns reproductive cycle to increase the productivity of penaeid shrimp. CFO on feed should be used at a dose of 6%.

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