scholarly journals Omega-3 Fatty Acids for Sport Performance—Are They Equally Beneficial for Athletes and Amateurs? A Narrative Review

Nutrients ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3712
Author(s):  
Frank Thielecke ◽  
Andrew Blannin
Keyword(s):  
Fatty Acids ◽  
Immune Modulation ◽  
Enhanced Recovery ◽  
Sport Performance ◽  
The Body ◽  
Endurance Capacity ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Beneficial Effects ◽  
Clinical Endpoints

Omega-3 fatty acids, specifically eicosapentanoic acid (EPA, 20:5n-3) and docosahexanoic acid (DHA, 22:6n-3) are receiving increasing attention in sports nutrition. While the usual focus is that of athletes, questions remain if the different training status between athletes and amateurs influences the response to EPA/DHA, and as to whether amateurs would benefit from EPA/DHA supplementation. We critically examine the efficacy of EPA/DHA on performance, recovery and injury/reduced risk of illness in athletes as well as amateurs. Relevant studies conducted in amateurs will not only broaden the body of evidence but shed more light on the effects of EPA/DHA in professionally trained vs. amateur populations. Overall, studies of EPA/DHA supplementation in sport performance are few and research designs rather diverse. Several studies suggest a potentially beneficial effect of EPA/DHA on performance by improved endurance capacity and delayed onset of muscle soreness, as well as on markers related to enhanced recovery and immune modulation. The majority of these studies are conducted in amateurs. While the evidence seems to broadly support beneficial effects of EPA/DHA supplementation for athletes and more so in amateurs, strong conclusions and clear recommendations about the use of EPA/DHA supplementation are currently hampered by inconsistent translation into clinical endpoints.

scholarly journals Omega-3 Polyunsaturated Fatty Acids Inhibit the Function of Human URAT1, a Renal Urate Re-Absorber

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1601 ◽  
Author(s):  
Hiroki Saito ◽  
Yu Toyoda ◽  
Tappei Takada ◽  
Hiroshi Hirata ◽  
Ami Ota-Kontani ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Human Health ◽  
Serum Urate ◽  
The Body ◽  
Omega 3 ◽  
Beneficial Effects ◽  
Uricosuric Agents ◽  
Transport Assay ◽  
The Impact

The beneficial effects of fatty acids (FAs) on human health have attracted widespread interest. However, little is known about the impact of FAs on the handling of urate, the end-product of human purine metabolism, in the body. Increased serum urate levels occur in hyperuricemia, a disease that can lead to gout. In humans, urate filtered by the glomerulus of the kidney is majorly re-absorbed from primary urine into the blood via the urate transporter 1 (URAT1)-mediated pathway. URAT1 inhibition, thus, contributes to decreasing serum urate concentration by increasing net renal urate excretion. Here, we investigated the URAT1-inhibitory effects of 25 FAs that are commonly contained in foods or produced in the body. For this purpose, we conducted an in vitro transport assay using cells transiently expressing URAT1. Our results showed that unsaturated FAs, especially long-chain unsaturated FAs, inhibited URAT1 more strongly than saturated FAs. Among the tested unsaturated FAs, eicosapentaenoic acid, α-linolenic acid, and docosahexaenoic acid exhibited substantial URAT1-inhibitory activities, with half maximal inhibitory concentration values of 6.0, 14.2, and 15.2 μM, respectively. Although further studies are required to investigate whether the ω-3 polyunsaturated FAs can be employed as uricosuric agents, our findings further confirm FAs as nutritionally important substances influencing human health.

Analgesia enhancement and prevention of tolerance to morphine: beneficial effects of combined therapy with omega-3 fatty acids

2015 ◽  
Vol 67 (9) ◽  
pp. 1251-1262 ◽  
Author(s):  
Graciela E. Escudero ◽  
Carolina B. Romañuk ◽  
María E. Toledo ◽  
María E. Olivera ◽  
Ruben H. Manzo ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Combined Therapy ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Beneficial Effects

scholarly journals An Overview of Analeptic Applications of Omega-3 Fatty Acids

2021 ◽  
pp. 95-118
Author(s):  
Bharat Kwatra ◽  
Harsimran Kaur ◽  
Joydip Majumdar ◽  
Mahek Shah ◽  
Mansi Upadhyaya ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Fatty Acids ◽  
Cardiovascular Health ◽  
The Body ◽  
Omega 3 Fatty Acids ◽  
Skin Disorders ◽  
Omega 3 ◽  
Pufa Ratio ◽  
Omega 6 ◽  
Anti Inflammatory

This article is an examination of the Analeptic Applications of Omega-3. The scientific development and subsequent clinical applications of Omega-3 in Healthcare continue to influence researchers all over the globe today. This article examines the research done and published by researchers and scientists. Consideration of current trends and data in scientific queries and demonstrates further aspects of the applications of Omega-3 on various health backgrounds, including. Cardiovascular Health: The study addresses the comparison of Omega-3 and Omega-6 in cardiovascular diseases. Higher intake of dietary Omega-3 helps activation, inhibition, and alteration of metabolic and signaling pathways which is associated with better cardiovascular health, while Omega-6 decreases the risk of coronary heart diseases and cardiovascular disease mortality. Immunology: Omega-3 Polyunsaturated Fatty Acids (PUFAs) have been found to show an anti-inflammatory effect in the body by downregulating the activation of various immune cells. They regulate immunological functions via eicosanoids and resolvins which are anti-inflammatory. External supplementation can reduce chronic and acute inflammation as well as reduce the chances of graft rejection. The regulatory effect is shown by modifying gene expression and/or signal transduction in human cells. They are also involved in altering the membrane composition of Fatty Acids(FA) and as a result, they affect the lipid raft structure and also membrane trafficking. Joint Health: The study shows the effects of omega-3 and other fatty acid consumption in Rheumatoid Arthritis(RA), bone marrow lesions, and knee cartilage lesions. It notes the interrelations between synovitis, plasma levels of Omega-3 and Omega-6 PUFAs in OsteoArthritis (OA) patients along with risk factors for OA, which could help consider liable treatments for improvement of OA. The study highlights the importance of the Omega-6:Omega-3 PUFA ratio and clinical and functional outcome measures which can help us in better understanding the role of PUFAs and possible treatments for people with knee osteoarthritis while showing the effect of Omega-3 fatty acids on muscle health in RA. Skin Disorders: Fish oils rich in PUFAs are reported to improve several inflammatory disorders, including rheumatoid arthritis and psoriasis. They have also been broadly reported as a potential supplement to ameliorate the severity of some skin disorders such as photoaging, skin cancer, allergy, dermatitis, cutaneous wounds, and melanogenesis. The significance of omega-3 in skin structure was proved by describing a syndrome caused by stringent fat reduction in the diet that leads to erythema with scaling, hair loss, itching, and increased water loss.

scholarly journals SCREENING OF FUNGI FOR PRODUCTION AND PURIFICATION OF OMEGA-3 FATTYACID

2021 ◽  
Vol 10 (4) ◽  
pp. 3089-3093
Author(s):  
Priya A Shanmuga
Keyword(s):  
Fatty Acids ◽  
Incubation Temperature ◽  
Lipid Production ◽  
Trichoderma Viride ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Beneficial Effects ◽  
Omega 6 ◽  
Initial Ph ◽  
Fat Soluble Vitamins

Omega fatty acids, major importance in the prevention or treatment of a range of human diseases or disorders related with inflammation. These fatty acids are found in transgenic plants, fungi, and animals and even in microorganisms but in major amounts can be extracted from fatty fish. However, due to bioaccumulation of fat-soluble vitamins and high levels of saturated and omega-6 fatty acids, they may have deleterious health effects. It becomes necessary to search for novel and rich sources containing omega-3 fatty acids and one of the alternatives include fungi. The present study deals with production and purification of omega-3 fatty acids from Trichoderma viride and Aspergillus niger. In the present study, the main objective was to explore the beneficial effects of fungi for the maximum lipid production through optimized conditions and the results clearly showed that Trichoderma viride was the significantly highest lipid producer, with lipid production at initial pH 6.0 and incubation temperature 40℃.

scholarly journals PENENTUAN KANDUNGAN LEMAK DAN KOMPOSISI ASAM-ASAM LEMAK PADA BAGIAN BADAN IKAN GABUS (Channa striata) BUDIDAYA DAN LIAR

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Alvy M. Umage ◽  
Julius Pontoh ◽  
Lidya I. Momuat
Keyword(s):  
Fatty Acids ◽  
Gas Chromatography ◽  
Fatty Acid ◽  
Extraction Method ◽  
Fat Content ◽  
The Body ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Channa Striata

ABSTRAK Telah dilakukan penentuan kandungan lemak dan komposisi asam-asam lemak pada bagian badan ikan gabus (Channa striata) budidaya dan liar. Penelitian ini bertujuan untuk mengetahui berapa kandungan lemak dan komposisi asam lemak pada bagian badan ikan gabus (Channa striata) budidaya dan liar. Kandungan lemak dilakukan menggunakan metode ektraksi dan diperoleh kandungan lemak bagian badan ikan gabus budidaya 0,07% dan ikan gabus liar 0,01%. Lemak ikan diderivatisasi dan dianalisis menggunakan kromatografi gas dan diperoleh komposisi asam lemak tertinggi pada bagian badan ikan gabus budidaya adalah asam lemak oleat 37,1% diikuti  dan diikuti oleh asam lemak palmitat 25,6% sedangkan asam lemak tertinggi pada bagian badan ikan gabus liar adalah asam lemak palmitat 28,6% dan diikuti asam lemak oleat 16,9%. Kandungan asam lemak omega-3 pada bagian badan ikan gabus budidaya 5,6% dan ikan gabus liar 9,0%. Kata kunci: Asam lemak, ikan gabus budidaya dan liar, kromatografi gas  ABSTRACT Determination of fat content and composition of fatty acids in the body of snakehead (Channa striata) from cultivated and wild sources. This study aims to determine how much fat content and composition fatty acids in the body of snakehead (Channa striata) from cultivated and wild sources. The fat content were carried out using the extraction method. The fat content of cultured snakehead body was 0.07% and that of wild fish was 0.01%. Fish fats were derivatized and analyzed using gas chromatography and the highest fatty acid composition on the body of cultivated snakehead fish is 37.1% oleic fatty acids followed by 25.6% palmitic fatty acids while the highest fatty acid in the body of a wild snakehead fish is 28.6% palmitic fatty acid and followed by 16.9% oleic fatty acid. The content of omega-3 fatty acids in the body of cultivated snakehead fish is 5.6% and 9.0% on wild snakehead fish. Keywords: Fatty acids, wild and cultivated snakehead fish, gas chromatography 

Beneficial effects of probiotic combination with omega-3 fatty acids in NAFLD: a randomized clinical study

2018 ◽  
Vol 109 (6) ◽  
Author(s):  
Nazarii Kobyliak ◽  
Ludovico Abenavoli ◽  
Tetyana Falalyeyeva ◽  
Galyna Mykhalchyshyn ◽  
Luigi Boccuto ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Clinical Study ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Beneficial Effects ◽  
Randomized Clinical Study

scholarly journals Omega-3 fatty acids and blood pressure

2012 ◽  
Vol 107 (S2) ◽  
pp. S195-S200 ◽  
Author(s):  
Jorge Cabo ◽  
Rodrigo Alonso ◽  
Pedro Mata
Keyword(s):  
Blood Pressure ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Mild Hypertension ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Beneficial Effects ◽  
Metabolic Functions ◽  
Blue Fish ◽  
High Doses

Epidemiological and clinical studies suggest that consumption of omega (ω-3) polyunsaturated fatty acids (PUFA) contributes to the reduction of cardiovascular mortality through different mechanisms including modulation of cellular metabolic functions, gene expression and beneficial effects on lipid profile or blood pressure. The aim of the study is to review the effects of ω-3 PUFA supplemented as fish oil or blue fish in blood pressure. The analysis of different studies suggests that high doses ω-3 PUFA ( ≥  3 g/day) produces a small but significant decrease in blood pressure, especially systolic blood pressure, in older and hypertensive subjects; however, the evidence is not consistent among different studies. ω-3 polyunsaturated fatty acids consumption might have a place in the control of patients with mild hypertension before starting drug treatment and of those who prefer changes of lifestyles like diet.

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