scholarly journals Clinical and instrumental criteria in predicting the clinical course of chronic posttraumatic uveitis after penetrating ocular trauma

2012 ◽  
Vol 93 (5) ◽  
pp. 764-767
Author(s):  
N M Maracheva ◽  
I E Panova
Keyword(s):  
Optic Nerve ◽  
Clinical Examination ◽  
Ocular Trauma ◽  
Clinical Course ◽  
Fluid Pressure ◽  
Control Group ◽  
Asymmetry Coefficient ◽  
Prognostic Criteria ◽  
Post Traumatic ◽  
Penetrating Ocular Trauma

Aim. To identify the prognostic criteria for the recovery or transformation to chronic form in patients with prolonged clinical course of uveitis associated with penetrating ocular trauma basing on the results of clinical examination and instrumental methods. Methods. 120 patients with chronic clinical course of post-traumatic uveitis were examined 2-3 months after the penetrating ocular trauma using clinical examination and ultrasonography of eye and orbita. 1st group consisted of 60 convalescents, 2nd included 60 patients with chronic disease. The control group consisted of 40 healthy volunteers. Ultrasonography included measurement of innermost eye coat thickness and the retrobulbar part of the optic nerve thickness measured 10 mm behind the eyeball bilaterally. Results were statistically analyzed. Results. Prognostic criteria for recovery or chronic inflammation development in chronic post-traumatic uveitis were found. They are: G-index and interocular asymmetry coefficient of innermost eye coat and optic nerve thickness. At calculation of G-index, which characterizes inflammatory consequences of trauma, presence of cornea imbibition, rubeosis iridis, cataract, vitreous body fibrosis, pulled-in cornea and sclera scars, retinal and choroidal detachment, the eyeball subatrophy, decreased eye fluid pressure, optic nerve thickening. The value of all the parameters equaled 1. An interocular thickness asymmetry coefficient characterized innermost eye coat thickness or optic nerve thickness ratio in injured eye compared to other eye. 2-3 weeks after the trauma characteristic G-index value of G ≥4, an interocular asymmetry coefficient value of ≥1,3 for innermost eye coat thickness and ≥1,1 for optic nerve thickness are the indicators of a high risk of chronic development. Lesser values predict recovery. Conclusion. Use of the set of found prognostic criteria in patients with prolonged clinical course of uveitis provides high prognosis accuracy of 93,3% at predicting recovery or chronic uveitis development.

scholarly journals Optic Nerve Avulsion and Retinal Detachment After Penetrating Ocular Trauma: Case Report

2018 ◽  
pp. 89-91 ◽  
Author(s):  
Mehmet Fatih Kağan Değirmenci ◽  
Nilüfer Yalçındağ ◽  
Hüban Atilla
Keyword(s):  
Case Report ◽  
Optic Nerve ◽  
Retinal Detachment ◽  
Ocular Trauma ◽  
Trauma Case ◽  
Penetrating Ocular Trauma

Results of osteopathic correction of patients with post-traumatic coccygodynia

2019 ◽  
pp. 19-27
Author(s):  
Yu. V. Antonova ◽  
A. M. Iskandarov ◽  
I. B. Mizonova
Keyword(s):  
Quality Of Life ◽  
Emotional State ◽  
Pain Syndrome ◽  
Control Group ◽  
Life Questionnaire ◽  
Treatment Area ◽  
Diffi Cult ◽  
Osteopathic Treatment ◽  
Post Traumatic

Introduction.Coccygodynia is a multidisciplinary disease which is diffi cult to treat. It seriously limits the ability to work and signifi cantly affects the quality of life of patients. The study of somatic dysfunctions in patients with coccygodynia and the analysis of the results of osteopathic treatment of such patients makes it possible to justify the necessity of osteopathic correction of coccygodynia.Goal of the study— to determine the structure of the leading somatic dysfunctions in patients with coccygodynia and to study the effectiveness of osteopathic treatment of this pathology.Materials and methods.The study involved 44 patients from 25 to 65 years old, randomly divided into two groups. The main group of 24 people (20 women and 4 men) received osteopathic treatment, in accordance with the identifi ed leading somatic dysfunctions. Patients of the control group (16 women and 4 men) were treated locally with soft manual techniques (the treatment area was limited by the pelvic region). In order to assess the results of the treatment, we examined the intensity of the pain syndrome and the psycho-emotional state of patients. The severity of the pain syndrome was assessed in accordance with the visual analogue scale (VAS). The psycho-emotional state (with physical and mental components) was assessed with the help of the SF-36 quality of life questionnaire.Results.Somatic dysfunctions typical for patients with coccygodynia have been identifi ed. Osteopathic treatment has proven to be more effective in comparison with local manual therapy of coccygodynia both in early periods and in 3 months after the end of the treatment course.Conclusion.Osteopathic treatment of post-traumatic coccygodynia is effective, and can be recommended for treatment of such patients.

scholarly journals Adult-onset sporadic chorea: real-world data from a single-centre retrospective study

2021 ◽  
Author(s):  
Roberta Bovenzi ◽  
Matteo Conti ◽  
Rocco Cerroni ◽  
Mariangela Pierantozzi ◽  
Alessandro Stefani ◽  
...  
Keyword(s):  
Clinical Examination ◽  
Real World ◽  
Laboratory Tests ◽  
Clinical Course ◽  
Diagnostic Workup ◽  
Adult Onset ◽  
Real World Data ◽  
Term Outcome ◽  
Long Term Outcome ◽  
World Data

Abstract Background Adult-onset sporadic chorea includes a wide and heterogeneous group of conditions whose differential diagnosis and treatments are often challenging and extensive. Objectives To analyse retrospectively cases of adult-onset sporadic chorea from a single Italian centre to provide insights for a practical approach in the management of these patients. Methods A total of 11,071 medical charts from a 9-year period (2012–2020) were reviewed, identifying 28 patients with adult-onset sporadic chorea (genetic forms excluded). All available data regarding phenomenology, diagnostic workup, aetiology, treatments, and long-term outcome from this cohort were collected and analysed. Results Adult-onset sporadic chorea occurred more frequently in females and presented with an acute-subacute onset. Cerebrovascular diseases accounted for 68% of aetiology; further causes were structural brain lesions, internal diseases, and other movement disorder syndromes. Clinical course was mild, with spontaneous resolution or minimal disturbances in 82% of cases. Neuroimaging was fundamental to diagnose 76% of adult-onset sporadic chorea, an appropriate clinical examination contributed to the 14% of diagnoses, whereas basic laboratory tests to the 10%. Conclusions Revision of real-world data of adult-onset sporadic chorea patients from a single Italian cohort suggests that an accurate clinical examination, neuroimaging, and routine laboratory tests are useful to identify those cases underlying potentially severe but treatable conditions. Although in the majority of cases adult-onset sporadic chorea has mild clinical course and good response to symptomatic treatments, it is essential to run a fast diagnostic workup.

scholarly journals Novel in vivo depiction of optic nerves hemorrhages in child abuse: a 3D-SWI pilot study

2021 ◽  
Author(s):  
Giulio Zuccoli
Keyword(s):  
Optic Nerve ◽  
Mass Effect ◽  
Abusive Head Trauma ◽  
Superficial Siderosis ◽  
Susceptibility Artifacts ◽  
Female Ratio ◽  
Optic Nerves ◽  
Statistical Correlations ◽  
Post Traumatic

Abstract Purpose Until now, the diagnosis of optic nerves hemorrhages in abusive head trauma (AHT) has been obtained only in the postmortem setting. The aim of the IRB-approved study was to assess the presence of optic nerves hemorrhages in AHT patients using 3D-SWI. Methods Thirteen children with a final confirmed multidisciplinary diagnosis of AHT underwent coronal and axial 3D-SWI imaging of the orbits. The presence of optic nerve sheath (ONS) hemorrhages was defined by thickening and marked 3D-SWI hypointensity of the ONS, resulting in mass effect upon the CSF space. Optic nerve (ON) hemorrhages were defined by areas of susceptibility artifacts in the ON parenchyma. Superficial siderosis was defined by susceptibility artifact coating the ON. Furthermore, data about post-traumatic deformity of the ONS at the head of the optic nerve were collected. Results The average age of the population was 7.9 ± 5.9 months old. The average GCS was 11.8 ± 4.5. The male to female ratio was 7:6. ONS hemorrhages were identified in 69.2% of cases. Superficial siderosis and ON hemorrhages were identified in 38.5 and 76.9% of cases, respectively. 3D-SWI also depicted traumatic deformity of the ONS at the level of the optic nerve head in 10 cases (76.9%). No statistical correlations were identified between RetCam findings and 3D-SWI findings or GCS and ON hemorrhages. Conclusion This research shows that dedicated MRI with volumetric SWI of the orbits can depict hemorrhages in the ON, ONS, and ONS injury, in AHT victims.

Gamma-Irradiated Cornea in Combat-related Ocular Trauma

2020 ◽  
Author(s):  
Brian M Davis ◽  
Carson Clabeaux ◽  
Anton Vlasov ◽  
Paul Houghtaling
Keyword(s):  
Ocular Trauma ◽  
Cost Savings ◽  
Corneal Tissue ◽  
Significant Cost ◽  
Visual Rehabilitation ◽  
Military Health ◽  
Corneal Injury ◽  
Gamma Irradiated ◽  
The Military ◽  
Penetrating Ocular Trauma

ABSTRACT Corneal injury is a known risk for deployed troops worldwide. To the authors’ knowledge, there has been no reported use of gamma-irradiated corneas in the setting of severe corneal trauma. Our report highlights the case of a 36-year-old active duty solider who sustained bilateral penetrating ocular trauma from a nearby ordnance explosion. We propose that ocular surgeons should consider utilizing gamma-irradiated corneas in (1) a situation where the corneal tissue is so damaged that it would be challenging to accomplish an adequate repair while providing the opportunity for future visual rehabilitation and (2) remote and/or deployed environments where storage of fresh donor tissue is limited. The long shelf life of gamma-irradiated corneas reduces the need for specialized storage equipment and the need for continuous resupply, both potentially leading to significant cost savings for the Military Health System.

Primary posterior chamber IOL implantation in penetrating ocular trauma

1993 ◽  
Vol 17 (3) ◽  
pp. 137-141 ◽  
Author(s):  
Tat Keong Chan ◽  
Graeme Mackintosh ◽  
Ronald Yeoh ◽  
Arthur SM Lim
Keyword(s):  
Ocular Trauma ◽  
Posterior Chamber ◽  
Iol Implantation ◽  
Penetrating Ocular Trauma ◽  
Posterior Chamber Iol

Post-traumatic regeneration of optic nerve axons: Comparison between fish and rodents

1992 ◽  
Vol 55 ◽  
pp. 37
Author(s):  
M. Schwartz ◽  
S. Eitan ◽  
E. Blaugrund ◽  
I. Cohen ◽  
V. Lavie ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Post Traumatic

scholarly journals Research on Influences of Transient High IOP during LASIK on Retinal Functions and Ultrastructure

2009 ◽  
Vol 2009 ◽  
pp. 1-5 ◽  
Author(s):  
Haixia Zhao ◽  
Yude Ai ◽  
Chunmei Niu ◽  
Wenying Guan ◽  
Xiaoling Li ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Normal Control ◽  
Control Group ◽  
Sharp Change ◽  
Experimental Control ◽  
New Zealand White Rabbits ◽  
Prolonged Recovery ◽  
Flash Visual Evoked Potential ◽  
Negative Suction ◽  
Retinal Functions

Objectives. To study the influences of transient high intraocular pressure(IOP) during LASIK on retinal functions and ultrastructure.Methods. Thirty-two New Zealand white rabbits were randomly divided into normal control, experimental control, negative suction 20 s and negative suction 3 min groups. The experimental control group was treated only by laser. Rabbit eyes received suction for different periods of time (20 s, 3 min) by negative pressure generator in different groups. The changes of neuro-optic and retinal ultrastructure were observed under electron and light microscopes; retinal neurofunctional changes were observed with flash-visual evoked potential (F-VEP) and flash-electroreinogram (F-ERG).Results. There was no obvious change in optic nerve, retina, ERG a-wave and b-wave in normal control and experimental control groups. There were slight changes in tissues of optic nerve and retina at various times of suction 20 s compared with control group, and a sharp change in suction 3 min group within 14d after operation, but these changes recovered at 28d. Amplitude of ERG b-wave observed at different time will decrease with suction periods prolonged. It can recover to normal level with the prolonged recovery periods. Amplitude and incubation period of ERG a-wave and VEP-P did not change significantly after different duration of suction.Conclusions. The transient high IOP during LASIK might have influence on retinal function and ultrastructure, but these changes were reversible.

Changes of 5-HT1A receptor in the dorsal raphe nucleus in the rat model of Post-Traumatic Stress Disorder

2011 ◽  
Vol 26 (S2) ◽  
pp. 1081-1081
Author(s):  
F.F. Luo ◽  
F. Han ◽  
X.Y. Shi
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Dorsal Raphe Nucleus ◽  
Dorsal Raphe ◽  
Raphe Nucleus ◽  
Control Group ◽  
Post Traumatic Stress ◽  
Post Traumatic ◽  
Dorsal Raphé

IntroductionPosttraumatic stress disorder (PTSD) is characterized mainly by symptoms of reexperiencing, avoidance and hyperarousal as a consequence of catastrophic and traumatic events that are distinguished from ordinary stressful life events. Single-prolonged stress (SPS) is an established animal model for post-traumatic stress disorder (PTSD). The dorsal raphe nucleus (DR)-serotonin (5-HT) system is dramatically affected by swim stress and has been implicated in affective disorders. The 5-HT1A receptor (5-HT1AR) is critically involved in regulating mood and anxiety levels.ObjectiveIn this study, we investigated changes in the expression of 5-HT1AR in DR of rats after SPS which may reveal part of the pathogenesis of PTSD.MethodsRats were randomly divided into 24h, 4d and 7d groups after SPS and a normal control group, 5-HT1AR expression in DR was examined using immunohistochemistry, western blotting and reverse transcription polymerase chain reaction.ResultsThe expression of 5-HT1AR in DR after SPS exposure was increased when compared to that in the control group (P < 0.05).ConclusionThese findings suggest increase of 5-HT1AR in DR of SPS rats, which may play important roles in the pathogenesis of PTSD rats.

Primary cataract extraction and intraocular lens implantation in penetrating ocular trauma

Ophthalmology ◽  
2001 ◽  
Vol 108 (6) ◽  
pp. 1099-1103 ◽  
Author(s):  
Joseph Moisseiev ◽  
Fani Segev ◽  
Noga Harizman ◽  
Tal Arazi ◽  
Ygal Rotenstreich ◽  
...  
Keyword(s):  
Intraocular Lens ◽  
Ocular Trauma ◽  
Cataract Extraction ◽  
Intraocular Lens Implantation ◽  
Lens Implantation ◽  
Penetrating Ocular Trauma
Sign in / Sign up

Export Citation Format

Share Document