scholarly journals Anti-Obesity Effect of a Mixture of Skim Milk, Red Ginseng Extract, and Black Raspberry Extract Fermented with Lactobacillus acidophilus on High-Fat Diet-Fed Obese Mice

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Eun Ji Yum ◽  
Nam Keun Lee ◽  
Jisun Oh ◽  
Chang Hyun Lee ◽  
Mi Jin Oh ◽  
...  
2014 ◽  
Vol 30 (4) ◽  
pp. 151 ◽  
Author(s):  
Hak-Yong Lee ◽  
Kwang-Hyun Park ◽  
Young-Mi Park ◽  
Dae-In Moon ◽  
Hong-Geun Oh ◽  
...  

2015 ◽  
Vol 39 (5) ◽  
pp. 612-621 ◽  
Author(s):  
Hee Jae Lee ◽  
Hana Jung ◽  
Hyunnho Cho ◽  
Keum Taek Hwang

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 926
Author(s):  
Seo Yeon Lee ◽  
Hyun Gyun Yuk ◽  
Seong Gyu Ko ◽  
Sung-Gook Cho ◽  
Gi-Seong Moon

Although the anti-obesity effect of Korean red ginseng (Panax ginseng Meyer) has been revealed, its underlying mechanisms are not clearly understood. Here, we demonstrate an involvement of gut microbiome in the inhibitory effect of Korean red ginseng on high-fat-diet (HFD)-induced mouse obesity, and further provides information on the effects of saponin-containing red ginseng extract (SGE) and saponin-depleted red ginseng extract (GE). Mice were fed with either SGE or GE every third day for one month, and their food intakes, fat weights, plasma glucose, and insulin and leptin levels were measured. Immunofluorescence assays were conducted to measure pancreatic islet size. Stools from the mice were subjected to metagenomic analysis. Both SGE and GE attenuated HFD-induced gain of body weight, reducing HFD-induced increase of food intakes and fat weights. They also reduced HFD-increased plasma glucose, insulin, and leptin levels, decreased both fasting and postprandial glucose concentrations, and improved both insulin resistance and glucose intolerance. Immunofluorescence assays revealed that they blocked HFD-induced increase of pancreatic islet size. Our pyrosequencing of the 16S rRNA gene V3 region from stools revealed that both SGE and GE modulated HFD-altered composition of gut microbiota. Therefore, we conclude that Korean red ginseng inhibits HFD-induced obesity and diabetes by altering gut microbiome.


2011 ◽  
Vol 92 (2) ◽  
pp. 388-396 ◽  
Author(s):  
Yong-Bum Song ◽  
Yu Ri An ◽  
Seung Jun Kim ◽  
Hye-Won Park ◽  
Jin-Wook Jung ◽  
...  

Obesity ◽  
2012 ◽  
Author(s):  
Gong-Rak Lee ◽  
Mi Kyung Shin ◽  
Dong-Joon Yoon ◽  
Ah-Ram Kim ◽  
Rina Yu ◽  
...  

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
E Changkyun Park ◽  
SY Lee ◽  
SH Yun ◽  
WY Kim ◽  
Y Yi ◽  
...  

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