Anti-Inflammatory Effect of Black Raspberry Seed Oil in High-Fat Diet-Induced Obese Mice

2015 ◽  
Vol 39 (5) ◽  
pp. 612-621 ◽  
Author(s):  
Hee Jae Lee ◽  
Hana Jung ◽  
Hyunnho Cho ◽  
Keum Taek Hwang
Keyword(s):  
High Fat Diet ◽  
Seed Oil ◽  
Black Raspberry ◽  
Obese Mice ◽  
High Fat ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Antihyperglycemic and Anti-Inflammatory Effects of StandardizedCurcuma xanthorrhizaRoxb. Extract and Its Active Compound Xanthorrhizol in High-Fat Diet-Induced Obese Mice

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Mi-Bo Kim ◽  
Changhee Kim ◽  
Youngwoo Song ◽  
Jae-Kwan Hwang
Keyword(s):  
High Fat Diet ◽  
Interleukin 1 ◽  
Liver Fat ◽  
Postprandial Blood Glucose ◽  
Obese Mice ◽  
High Fat ◽  
Necrosis Factor Alpha ◽  
Glucose Levels ◽  
Anticancer Properties ◽  
Anti Inflammatory

Xanthorrhizol, a natural compound isolated fromCurcuma xanthorrhizaRoxb. (Java turmeric), has been reported to possess antioxidant and anticancer properties; however, its effects on metabolic disorders remain unknown. The aim of the present study was to evaluate the effects of xanthorrhizol (XAN) andC. xanthorrhizaextract (CXE) with standardized XAN on hyperglycemia and inflammatory markers in high-fat diet- (HFD-) induced obese mice. Treatment with XAN (10 or 25 mg/kg/day) or CXE (50 or 100 mg/kg/day) significantly decreased fasting and postprandial blood glucose levels in HFD-induced obese mice. XAN and CXE treatments also lowered insulin, glucose, free fatty acid (FFA), and triglyceride (TG) levels in serum. Epididymal fat pad and adipocyte size were decreased by high doses of XAN (26.6% and 20.1%) and CXE (25.8% and 22.5%), respectively. XAN and CXE treatment also suppressed the development of fatty liver by decreasing liver fat accumulation. Moreover, XAN and CXE significantly inhibited production of inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), interleukin-1β(IL-1β), and C-reactive protein (CRP) in adipose tissue (27.8–82.7%), liver (43.9–84.7%), and muscle (65.2–92.5%). Overall, these results suggest that XAN and CXE, with their antihyperglycemic and anti-inflammatory activities, might be used as potent antidiabetic agents for the treatment of type 2 diabetes.

scholarly journals Fasting Induces an Anti-Inflammatory Effect on the Neuroimmune System Which a High-Fat Diet Prevents

Obesity ◽  
2011 ◽  
Vol 19 (8) ◽  
pp. 1586-1594 ◽  
Author(s):  
Desiree N. Lavin ◽  
Jennifer J. Joesting ◽  
Gabriel S. Chiu ◽  
Morgan L. Moon ◽  
Jia Meng ◽  
...  
Keyword(s):  
High Fat Diet ◽  
High Fat ◽  
Neuroimmune System ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Kiwifruit seed oil ameliorates inflammation and hepatic fat metabolism in high-fat diet-induced obese mice

2019 ◽  
Vol 52 ◽  
pp. 715-723 ◽  
Author(s):  
Linlin Qu ◽  
Qingqing Liu ◽  
Qi Zhang ◽  
Dan Liu ◽  
Chao Zhang ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Seed Oil ◽  
Fat Metabolism ◽  
Obese Mice ◽  
High Fat ◽  
Hepatic Fat

Anti-inflammatory effect of β2 adrenergic stimulation on circulating monocytes with a pro-inflammatory state in high-fat diet-induced obesity

2019 ◽  
Vol 80 ◽  
pp. 564-572 ◽  
Author(s):  
Isabel Gálvez ◽  
Leticia Martín-Cordero ◽  
María Dolores Hinchado ◽  
Alberto Álvarez-Barrientos ◽  
Eduardo Ortega
Keyword(s):  
High Fat Diet ◽  
Adrenergic Stimulation ◽  
High Fat ◽  
Diet Induced Obesity ◽  
Inflammatory State ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Anti‐inflammatory and metabolic mechanisms by which omega‐3 fatty acids improve insulin resistance in high fat diet‐induced obese mice

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Nishan Sudheera Kalupahana ◽  
Kate Claycombe ◽  
Taryn Stewart ◽  
Rachael Hadidsaz ◽  
Suzanne Booker ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Fatty Acids ◽  
High Fat Diet ◽  
Omega 3 Fatty Acids ◽  
Obese Mice ◽  
Omega 3 ◽  
High Fat ◽  
Improve Insulin Resistance ◽  
Anti Inflammatory

scholarly journals Oral administration of the milk casein-derived tripeptide Val-Pro-Pro attenuates high-fat diet-induced adipose tissue inflammation in mice

2014 ◽  
Vol 112 (4) ◽  
pp. 513-519 ◽  
Author(s):  
Kotaro Aihara ◽  
Mizuko Osaka ◽  
Masayuki Yoshida
Keyword(s):  
Adipose Tissue ◽  
Oral Administration ◽  
High Fat Diet ◽  
Tap Water ◽  
High Fat ◽  
The Metabolic Syndrome ◽  
Anti Inflammatory ◽  
Milk Casein ◽  
Inflammatory Macrophages ◽  
Inflammatory Effect

Inflammation of adipose tissue triggers the metabolic syndrome, atherosclerosis and CHD. In the present study, we investigated whether the milk casein-derived tripeptide valine-proline-proline (VPP) has an anti-inflammatory effect on the adipose tissue of high-fat diet (HFD)-fed mice. Male C57BL/6J mice (7 weeks of age) were fed ad libitum with either a HFD and plain tap water (HFD group) or a HFD and water containing 0·3 mg VPP/ml (HFD+VPP group) for 10 weeks. The results showed that the expression level of CD18 in the peripheral blood monocytes of the HFD+VPP group was significantly decreased compared with the level observed in those of the HFD group. Activated monocytes and pro-inflammatory macrophages were accumulated in the stromal vascular fractions of the adipose tissue from HFD-fed mice, which were significantly decreased in those supplemented with VPP. The formation of crown-like structures rich in pro-inflammatory macrophages was also significantly reduced in the adipose tissue of mice administered with VPP. Real-time PCR analysis revealed that the expression of monocyte chemoattractant protein-1 and that of the pro-inflammatory cytokine IL-6 in adipose tissue tend to be lower in the HFD+VPP group than in the HFD group. These observations indicate that oral administration of VPP exerts an anti-inflammatory effect on the adipose tissue of HFD-fed mice, which may eventually lead to the primary prevention of chronic inflammation-related diseases.

Sign in / Sign up

Export Citation Format

Share Document