scholarly journals Spontaneous mutations in CYC8 and MIG1 suppress the short chronological lifespan of budding yeast lacking SNF1/AMPK

2018 ◽  
Vol 5 (5) ◽  
pp. 233-248 ◽  
Author(s):  
Nazif Maqani ◽  
Ryan D. Fine ◽  
Mehreen Shahid ◽  
Mingguang Li ◽  
Elisa Enriquez-Hesles ◽  
...  
Keyword(s):  
Budding Yeast ◽  
Spontaneous Mutations ◽  
Chronological Lifespan

scholarly journals DNA Replication Stress Is a Determinant of Chronological Lifespan in Budding Yeast

PLoS ONE ◽  
2007 ◽  
Vol 2 (8) ◽  
pp. e748 ◽  
Author(s):  
Martin Weinberger ◽  
Li Feng ◽  
Anita Paul ◽  
Daniel L. Smith ◽  
Robert D. Hontz ◽  
...  
Keyword(s):  
Dna Replication ◽  
Budding Yeast ◽  
Replication Stress ◽  
Chronological Lifespan ◽  
Dna Replication Stress

scholarly journals A rapid, high-throughput method for determining chronological lifespan in budding yeast

2018 ◽  
Vol 5 (4) ◽  
pp. 106 ◽  
Author(s):  
Zachery R. Belak ◽  
Troy Harkness ◽  
Christopher H. Eskiw
Keyword(s):  
High Throughput ◽  
Budding Yeast ◽  
Chronological Lifespan ◽  
High Throughput Method

scholarly journals Hormesis of Glyceollin I, an Induced Phytoalexin from Soybean, on Budding Yeast Chronological Lifespan Extension

Molecules ◽  
2014 ◽  
Vol 19 (1) ◽  
pp. 568-580 ◽  
Author(s):  
Yuancai Liu ◽  
Ziyun Wu ◽  
Shengbao Feng ◽  
Xuena Yang ◽  
Dejian Huang
Keyword(s):  
Budding Yeast ◽  
Lifespan Extension ◽  
Chronological Lifespan ◽  
Glyceollin I

scholarly journals Coffee Extends Yeast Chronological Lifespan through Antioxidant Properties

2020 ◽  
Vol 21 (24) ◽  
pp. 9510
Author(s):  
Jadwiga Czachor ◽  
Michał Miłek ◽  
Sabina Galiniak ◽  
Karolina Stępień ◽  
Małgorzata Dżugan ◽  
...  
Keyword(s):  
Free Radicals ◽  
High Performance ◽  
Cell Function ◽  
Budding Yeast ◽  
Antioxidant Properties ◽  
Strand Break ◽  
Yeast Cells ◽  
Chromatography Method ◽  
Chronological Lifespan ◽  
The Impact

Aging is a multifactorial process accompanied by loss of cell function. Science has been looking for factors responsible for aging for many years. However, despite identifying a number of possible causes, the definite reason for aging has been elusive so far. One of the factors contributing to aging is oxygen free radicals. In this context, beneficial effects of coffee on various organisms, including humans, were investigated, although the results are far from unequivocal. In our research, we used the budding yeast—something of a workhorse in many studies, including the studies of aging. So far, the impact of coffee on the aging of cells in the budding yeast experimental setup has little known about it. Here, we provide strong evidence that coffee compounds, particularly flavonoids, are responsible for scavenging free radicals and longevity in yeast lacking Sod1, Sod2 and Rad52 proteins. In this paper, we compared Arabica and Robusta coffee types. We present an analysis of the concentration of caffeine and flavonoids measured by the High-Performance Liquid Chromatography method. We show that Robusta has a much greater antioxidant capacity than Arabica. We also conclude that coffee infusions significantly extend the chronological lifespan of the Saccharomyces cerevisiae yeast cells by protecting cells against reactive oxygen species, double DNA-strand break and decrease in metabolic activity.

scholarly journals Discovery of fifteen new geroprotective plant extracts and identification of cellular processes they affect to prolong the chronological lifespan of budding yeast

Oncotarget ◽  
2020 ◽  
Vol 11 (23) ◽  
pp. 2182-2203
Author(s):  
Pamela Dakik ◽  
Monica Enith Lozano Rodriguez ◽  
Jennifer Anne Baratang Junio ◽  
Darya Mitrofanova ◽  
Younes Medkour ◽  
...  
Keyword(s):  
Plant Extracts ◽  
Budding Yeast ◽  
Chronological Lifespan ◽  
Cellular Processes

Genomic stability disorders from budding yeast to humans

10.2741/s379 ◽  
2013 ◽  
Vol S5 (2) ◽  
pp. 396-411 ◽  
Author(s):  
Nicolas Carlos Hoch
Keyword(s):  
Budding Yeast ◽  
Genomic Stability
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