scholarly journals Spinal fusion with demineralized calf fetal growth plate as novel biomaterial in rat model: a preliminary study

10.14444/1005 ◽  
2014 ◽  
Vol 8 ◽  
pp. 5 ◽  
Author(s):  
Amin Bigham-Sadegh ◽  
Iraj Karimi ◽  
Ahmad Oryan ◽  
Elena Mahmoudi ◽  
Zahra Shafiei-Sarvestani
Keyword(s):  
Spinal Fusion ◽  
Growth Plate ◽  
Fetal Growth ◽  
Rat Model ◽  
Preliminary Study

Preliminary study of efficacy of hyaluronic acid on caustic esophageal burns in an experimental rat model

2013 ◽  
Vol 48 (4) ◽  
pp. 716-723 ◽  
Author(s):  
Muazez Cevik ◽  
Tuncer Demir ◽  
Cetin Ali Karadag ◽  
Muzaffer Aydin Ketani ◽  
Hakim Celik ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Rat Model ◽  
Experimental Rat Model ◽  
Preliminary Study

A rat model of maternal intermittent fasting during pregnancy impairs fetal growth but does not alter maternofetal folate transport

Placenta ◽  
2017 ◽  
Vol 57 ◽  
pp. 286 ◽  
Author(s):  
Rezwana Hussain ◽  
May Tassabehji ◽  
Nick Ashton ◽  
Jocelyn Glazier
Keyword(s):  
Fetal Growth ◽  
Rat Model ◽  
Intermittent Fasting ◽  
Folate Transport

The effect of copper deficiency on fetal growth and liver anti-oxidant capacity in the Cohen diabetic rat model

2012 ◽  
Vol 265 (2) ◽  
pp. 209-220 ◽  
Author(s):  
Zivanit Ergaz ◽  
Dana Shoshani-Dror ◽  
Claire Guillemin ◽  
Meytal Neeman-azulay ◽  
Liza Fudim ◽  
...  
Keyword(s):  
Fetal Growth ◽  
Rat Model ◽  
Copper Deficiency ◽  
Diabetic Rat ◽  
Anti Oxidant ◽  
Effect Of Copper ◽  
Diabetic Rat Model

GR/Sp3/HDAC1/UGDH signaling participated in the maternal dexamethasone‐induced dysplasia of the rat fetal growth plate

2020 ◽  
Vol 34 (9) ◽  
pp. 12834-12846
Author(s):  
Yinxian Wen ◽  
Huasong Shi ◽  
Zhixin Wu ◽  
Hao Xiao ◽  
Hui Wang ◽  
...  
Keyword(s):  
Growth Plate ◽  
Fetal Growth

scholarly journals Fetal programming effects of pentaerythritol tetranitrate in a rat model of superimposed preeclampsia

2020 ◽  
Vol 98 (9) ◽  
pp. 1287-1299
Author(s):  
Andy W. C. Man ◽  
Min Chen ◽  
Yawen Zhou ◽  
Zhixiong Wu ◽  
Gisela Reifenberg ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Glucose Tolerance ◽  
Fetal Growth ◽  
Rat Model ◽  
High Salt ◽  
Pentaerythritol Tetranitrate ◽  
High Salt Diet ◽  
Blood Pressure Elevation ◽  
Salt Diet ◽  
Normal Chow

Abstract Preeclampsia is a common medical condition during pregnancy and a major cause of maternal and prenatal mortality. The present study was conducted to investigate the effects of maternal treatment with pentaerythritol tetranitrate (PETN) in Dahl salt-sensitive rats (DSSR), a model of superimposed preeclampsia. F0 parental DSSR were treated with PETN (50 mg/kg) from the time point of mating to the end of lactation. Maternal PETN treatment improved fetal growth and had no effect on blood pressure in DSSR offspring fed with normal chow or high-salt diet. Upon high-fat diet (HFD) feeding, offspring from PETN-treated mother showed improved glucose tolerance despite similar weight gain. Unexpectedly, maternal PETN treatment significantly potentiated the HFD-induced blood pressure elevation in male DSSR offspring. Endothelium-derived hyperpolarization factor (EDHF)-mediated vasodilation was similar between NCD-fed and HFD-fed control offspring but was markedly reduced in HFD-fed PETN offspring. EDHF genes were downregulated in the vasculature of HFD-fed PETN offspring, which was associated with epigenetic changes in histone modifications. In conclusion, maternal PETN treatment in DSSR shows both beneficial and unfavorable effects. It improves fetal growth and ameliorates glucose tolerance in the offspring. Although maternal PETN treatment has no effect on blood pressure in offspring fed with normal chow or high-salt diet, the offspring is at higher risk to develop HFD-induced hypertension. PETN may potentiate the blood pressure response to HFD by epigenetic modifications of EDHF genes. Key messages The core findings of this article suggest that maternal PETN treatment of DSSR, a rat model of a spontaneous superimposed preeclampsia, leads to • Improvement of fetal growth; • No changes of maternal blood pressure or markers of preeclampsia; • Amelioration of HFD-induced glucose intolerance in adult offspring; • No changes in blood pressure development of the offspring on normal chow or high salt-diet; • Potentiation of blood pressure elevation of the offspring on HFD.

A preliminary study of the use of human adipose tissue-derived stem cells for the treatment of streptozotocin-induced diabetes mellitus in a rat model

2009 ◽  
Vol 19 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Mahmoud Abu-Abeeleh ◽  
Zuhair A. Bani Ismail ◽  
Khaled R. Alzaben ◽  
Sami A. Abu-Halaweh ◽  
Abdelkarim S. Aloweidi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Stem Cells ◽  
Adipose Tissue ◽  
Rat Model ◽  
Human Adipose Tissue ◽  
Streptozotocin Induced Diabetes ◽  
Preliminary Study

A preliminary study on fetal lung injury in a rat model of acute pancreatitis in pregnancy

2017 ◽  
Vol 213 (11) ◽  
pp. 1370-1377 ◽  
Author(s):  
Liang Zhao ◽  
Teng Zuo ◽  
Qiao Shi ◽  
Fang-chao Mei ◽  
Yu-pu Hong ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Lung Injury ◽  
Rat Model ◽  
Fetal Lung ◽  
Preliminary Study ◽  
In Pregnancy
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