Influence of human parathyroid hormone during orthodontic tooth movement and relapse in the osteoporotic rat model: A preliminary study

2018 ◽  
Vol 21 (3) ◽  
pp. 125-131 ◽  
Author(s):  
H. S. Lee ◽  
H. A. Heo ◽  
S. H. Park ◽  
W. Lee ◽  
S. W. Pyo
2021 ◽  
Vol 11 (11) ◽  
pp. 5268
Author(s):  
Zohaib Khurshid ◽  
Faris Yahya Asiri

Objective: The aim of this review is to summarize the effects of local and systemic PTH administration on periodontal tissues during orthodontic tooth movement. Materials and methods: An electronic search was conducted on the following databases: PubMed/MEDLINE, Google Scholar, SCOPUS and Embase. On PubMed/MEDLINE, the Medical Subject Headings (MeSH) keywords used were: “orthodontic tooth movement” OR (“tooth” (All Fields) AND “tooth movement” (All Fields)) OR “tooth movement” (All Fields)) AND (“parathyroid hormone”); all studies included using CONSORT. Results: After elimination of duplicates and articles not meeting our inclusion criteria, seven animal studies were included in this review. Although the majority of the studies suggest that PTH may a have a favorable outcome on OTM, most studies were found to have several sources of bias. Conclusion: Animal studies with minimal bias and long-term clinical studies are needed to ascertain the efficacy of intermittent PTH administration in improving the rate and retention of OTM.


2017 ◽  
Vol 48 (3) ◽  
pp. 199-208 ◽  
Author(s):  
Qihui Gu ◽  
Shuyu Guo ◽  
Dongyue Wang ◽  
Tingting Zhou ◽  
Lin Wang ◽  
...  

2016 ◽  
Vol 21 (2) ◽  
pp. 45-50 ◽  
Author(s):  
Mohammad Sadegh Ahmad Akhoundi ◽  
Rezvaneh Ghazanfari ◽  
Shahroo Etemad-Moghadam ◽  
Mojgan Alaeddini ◽  
Azam Khorshidian ◽  
...  

ABSTRACT Introduction: Osteoclasts and osteoblasts are responsible for regulating bone homeostasis during which the trace element zinc has been shown to exert a cumulative effect on bone mass by stimulating osteoblastic bone formation and inhibiting osteoclastic bone resorption. Objective: The aim of the present study was to investigate the effects of zinc (Zn) on orthodontic tooth movement (OTM) in a rat model. Material and Methods: A total of 44 male Wistar rats were divided into four groups of 11 animals each and received 0, 1.5, 20 and 50 ppm Zn in distilled water for 60 days. In the last 21 days of the study, nickel-titanium closed coil springs were ligated between maxillary right incisors and first molars of all rats, and tooth movement was measured at the end of this period. Histological analysis of hematoxylin/eosin slides was performed to assess root resorption lacunae, osteoclast number and periodontal ligament (PDL) width. Results: Mean OTM was calculated as 51.8, 49.1, 35.5 and 45 µm in the 0, 1.5, 20 and 50 ppm zinc-receiving groups, respectively. There were no significant differences in neither OTM nor histological parameters among the study groups (p > 0.05). Conclusion: According to the results obtained in the current investigation, increase in supplementary zinc up to 50 ppm does not affect the rate of OTM neither bone and root resorption in rats.


2006 ◽  
Vol 6 (5) ◽  
pp. 33S-34S
Author(s):  
Yuichiro Abe ◽  
Masahiko Takahata ◽  
Manabu Ito ◽  
Kuniyoshi Abumi ◽  
Akio Minami

2013 ◽  
Vol 16 (3) ◽  
pp. 161-168 ◽  
Author(s):  
L. Young ◽  
I. Binderman ◽  
A. Yaffe ◽  
L. Beni ◽  
A. D. Vardimon

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