scholarly journals The Association between Mast Cell Distribution and Acupoint Specificity: A Comprehensive Review

2020 ◽  
Vol 37 (3) ◽  
pp. 145-158
Author(s):  
JeongYeon Ji ◽  
Sun-Jeong Bae ◽  
Ju-Young Oh ◽  
Hyuk-Sang Jung ◽  
Hi-Joon Park
Pathology ◽  
1975 ◽  
Vol 7 (4) ◽  
pp. 307-318 ◽  
Author(s):  
L.C. Yong ◽  
S. Watkins ◽  
D.L. Wilhelm

1995 ◽  
Vol 25 (1) ◽  
pp. 41-50 ◽  
Author(s):  
S. M. BADDELEY ◽  
A. S. BACON ◽  
J. I. McGILL ◽  
S. L. LIGHTMAN ◽  
S. T. HOLGATE ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-15
Author(s):  
Xuezhi Wang ◽  
Meng Huang ◽  
Hongwei Yang ◽  
Di Zhang ◽  
Wei Yao ◽  
...  

Acupuncture is a medical modality based on the theory of traditional Chinese medicine, and its effect is relatively dependent on acupoint specificity. However, there is little knowledge on acupoint specificity versus acupuncture outcomes because of the deficiency of rigorous investigation on this topic, which has impeded the growing legitimacy of acupuncture in the mainstream of medicine as an evidence-based therapy. Therefore, it is of utmost importance to clarify this critical issue. The present study aims to verify the phenomenon of acupoint specificity in acupuncture-induced cardiovascular regulation and explore the biological mechanism by measuring mast cells’ degranulation and adenosine release. This study was conducted to explore the specificity of acupoints in an acute bradycardia rabbit model. After electroacupuncture (EA) stimulation at PC6, PC control (con) 1, PC con 2, LU7, LI11, and nonacupoint, only the PC6 group showed a significant improvement in relative heart rate as compared to that of the model group. There was no significant difference between the relative heart rate of other EA groups and that of the model group. Historical results also showed that the ratio of degranulated mast cells in PC6 was significantly higher than other acupoints and control points. From the results of high-performance liquid chromatography (HPLC), a transient elevation of adenosine concentration during EA was only observed on acupoints and control points ( P < 0.05 ) along the pericardium meridian. The EA-induced adjustment on acute bradycardia exhibits a relative specificity of acupoints, which may be related to mast cell degranulation and adenosine release in local acupoint areas. Increased degranulation of mast cells and augmentation of adenosine release during EA may be the mechanisms for PC6 having significantly better acupuncture effects than other acupoints and nonacupoints.


Blood ◽  
1951 ◽  
Vol 6 (1) ◽  
pp. 81-83 ◽  
Author(s):  
IVAN MOTA

Abstract Observations of thick smears of marrow obtained from the femur, tibia, humerus, sternum, and ribs (in rats), showed that in the first three bones, the number of mast cells was much higher than in the latter two bones. A method for the quantitative estimation of the total number of nucleated cells and of mast cells in the bone marrow of rats is presented. The method involves dilution of the marrow, in a red cell pipet, with a 1:50,000 solution of toluidine blue in 3 per cent acetic acid. This method confirmed the results of mast-cell distribution obtained in the study of marrow smears.


1995 ◽  
Vol 14 (6) ◽  
pp. 249-252 ◽  
Author(s):  
L. Aloe ◽  
A. Micera ◽  
P. Tirassa ◽  
L. Probert ◽  
G. Kollias

2019 ◽  
Vol 22 (1) ◽  
pp. 91-98 ◽  
Author(s):  
N. D Dimitrov ◽  
D. Y. Atanasova ◽  
N. S. Tomov ◽  
Y. A. Staykova-Pirovska ◽  
I. G. Ivanova ◽  
...  

The aim of this study was to investigate mast cell (MCs) distribution in the vicinity of the needle tract formed after acupuncture in Zusanli (ST36) acupoint in rats. MCs were detected by histochemistry, immunohistochemistry and transmission electron microscopy, and evaluated quantitatively. It was established that after acupuncture in ST36 acupoint the integrity of the epithelium, dermis, subcutaneous connective tissue, fascia, epimysium and striated muscles was disrupted and folded to the direction of the needle tract. In the thickened connective tissue MCs were observed close to the needle tract, without visible differences in their number along the tract, but most of them were with signs of degranulation, possibly due to acupuncture. It could be presumed that acupuncture in ST36 caused recruitment and activation of MCs followed by degranulation which most probably influenced the local microenvironment.


2016 ◽  
Vol Volume 9 ◽  
pp. 141-145 ◽  
Author(s):  
Kate Needham ◽  
Mitali Fadia ◽  
Jane Dahlstrom ◽  
Kirsti Harrington ◽  
Bruce Shadbolt ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document