Mast cell distribution in the uterus of cycling and pregnant hamsters

1964 ◽  
Vol 148 (3) ◽  
pp. 507-516 ◽  
Author(s):  
Elmer B. Harvey
Keyword(s):  
Pathology ◽  
1975 ◽  
Vol 7 (4) ◽  
pp. 307-318 ◽  
Author(s):  
L.C. Yong ◽  
S. Watkins ◽  
D.L. Wilhelm

1995 ◽  
Vol 25 (1) ◽  
pp. 41-50 ◽  
Author(s):  
S. M. BADDELEY ◽  
A. S. BACON ◽  
J. I. McGILL ◽  
S. L. LIGHTMAN ◽  
S. T. HOLGATE ◽  
...  

Blood ◽  
1951 ◽  
Vol 6 (1) ◽  
pp. 81-83 ◽  
Author(s):  
IVAN MOTA

Abstract Observations of thick smears of marrow obtained from the femur, tibia, humerus, sternum, and ribs (in rats), showed that in the first three bones, the number of mast cells was much higher than in the latter two bones. A method for the quantitative estimation of the total number of nucleated cells and of mast cells in the bone marrow of rats is presented. The method involves dilution of the marrow, in a red cell pipet, with a 1:50,000 solution of toluidine blue in 3 per cent acetic acid. This method confirmed the results of mast-cell distribution obtained in the study of marrow smears.


1995 ◽  
Vol 14 (6) ◽  
pp. 249-252 ◽  
Author(s):  
L. Aloe ◽  
A. Micera ◽  
P. Tirassa ◽  
L. Probert ◽  
G. Kollias

2019 ◽  
Vol 22 (1) ◽  
pp. 91-98 ◽  
Author(s):  
N. D Dimitrov ◽  
D. Y. Atanasova ◽  
N. S. Tomov ◽  
Y. A. Staykova-Pirovska ◽  
I. G. Ivanova ◽  
...  

The aim of this study was to investigate mast cell (MCs) distribution in the vicinity of the needle tract formed after acupuncture in Zusanli (ST36) acupoint in rats. MCs were detected by histochemistry, immunohistochemistry and transmission electron microscopy, and evaluated quantitatively. It was established that after acupuncture in ST36 acupoint the integrity of the epithelium, dermis, subcutaneous connective tissue, fascia, epimysium and striated muscles was disrupted and folded to the direction of the needle tract. In the thickened connective tissue MCs were observed close to the needle tract, without visible differences in their number along the tract, but most of them were with signs of degranulation, possibly due to acupuncture. It could be presumed that acupuncture in ST36 caused recruitment and activation of MCs followed by degranulation which most probably influenced the local microenvironment.


2016 ◽  
Vol Volume 9 ◽  
pp. 141-145 ◽  
Author(s):  
Kate Needham ◽  
Mitali Fadia ◽  
Jane Dahlstrom ◽  
Kirsti Harrington ◽  
Bruce Shadbolt ◽  
...  

Introduction: Natural agents with antioxidant and anti-inflammatory properties are safer than synthetic agents and may improve wound healing. Objective: The purpose of this study is to evaluate the in vivo wound healing potential of an ointment prepared from Trifolium repens hydroethanolic extract (T repens) concerning excisional wounds in a rat model. Materials and methods: Seventy-two adult Wistar rats were divided into 4 groups: a control group and 3 groups of animals treated with 1.5% T repens, 3% T repens, and 6% T repens. A full-thickness wound with an area of 314 mm2 was created in each rat. To investigate the effect of T repens on wound healing, the wound area, histological analyses (eg, angiogenesis, fibroblast, fibrocyte, mast-cell distribution), intracytoplasmic carbohydrate storage, and B-cell lymphoma 2-like protein 4 (BAX), B-cell lymphoma 2 (Bcl-2), and p53 gene expression in the wound tissue were evaluated for 21 days. Antioxidant activity was further measured by 2,20-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) and 2,2-Di(4-tert-octylphenyl)-1-picrylhydrazyl (DPPH) assays. Results: The animals in the treated groups showed higher wound contraction ratios (P ⟨ .05), angiogenesis, fibroblast, fibrocyte, and mast-cell distribution and intracytoplasmic carbohydrate storage compared with the control group (P ⟨ .05). Moreover, the topical administration of T repens increased the messenger ribonucleic acid (mRNA) level of Bcl-2 and reduced the BAX and p53 mRNA levels (P ⟨ .05). These findings further revealed the strong antioxidant activity of T repens. Conclusions: The topical administration of T repens accelerated wound healing by increasing angiogenesis; fibroblast, fibrocyte, and mast-cell distribution; intracytoplasmic carbohydrate storage; and modulation in genes involved in apoptosis in a rat model.


1956 ◽  
Vol s3-97 (38) ◽  
pp. 251-256
Author(s):  
I. MOTA ◽  
A. G. FERRI ◽  
S. YONEDA

The mast-cell distribution in the digestive tract of the rat, dog, cat, and guinea-pig was studied. In the rat mast-cells were present in the tongue, oesophagus, and forestomach, but practically absent from the glandular stomach, duodenum, ileum, and rectum. In the other species, mast-cells were numerous throughout the whole of the digestive tract, presenting a large individual variation. In the tongue and oesophagus mast-cells were found mainly in the submucosa and lamina propria, where they were located near the epithelium. In the stomach, mast-cells were more numerous in the mucosa and concentrated in the muscularis mucosae and between the necks of the glands. In the duodenum, mast-cells were also more numerous in the mucosa, being concentrated in the muscularis mucosae and frequently also in the summit of the villi. In the ileum and rectum mast-cells were less numerous than in the stomach and duodenum, keeping the same disposition as in these. The contribution of the mastcells to the histamine content of the digestive tract is discussed.


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