1′-Acetoxychavicol Acetate as a Potent Inhibitor of Tumor Promoter-induced Epstein-Barr Virus Activation fromLanguas gaianga, a Traditional Thai Condiment

1993 ◽  
Vol 57 (8) ◽  
pp. 1344-1345 ◽  
Author(s):  
Akira Kondo ◽  
Hajime Ohigashi ◽  
Akira Murakami ◽  
Jiwajinda Suratwadee ◽  
Koichi Koshimizu
1999 ◽  
Vol 63 (10) ◽  
pp. 1811-1812 ◽  
Author(s):  
Akira MURAKAMI ◽  
Miyuki TAKAHASHI ◽  
Suratwadee JIWAJINDA ◽  
Koichi KOSHIMIZU ◽  
Hajime OHIGASHI

2000 ◽  
Vol 78 (1) ◽  
pp. 31-40 ◽  
Author(s):  
Hironori Ohtsu ◽  
Reiko Tanaka ◽  
Yasuko In ◽  
Shunyo Matsunaga ◽  
Harukuni Tokuda ◽  
...  

A new podocarpane diterpene, 7α,15-dihydroxypodocarp-8(14)-en-13-one (1) and eight new abietane diterpenes, abiet-8(14)-en-7α,13β,15,18-tetraol (2), 7α,13β,15-trihydroxyabiet-8(14)-en-18-oic acid (3), 13β,18-dihydroxyabiet-8(14)-en-7-one (4), 13β,15,18-trihydroxyabiet-8(14)-en-7-one (5), 7-oxo-13β-methoxyabiet-8(14)- en-18-oic acid (7), abiet-8(14)-en-7α,12α,13β,18-tetraol (8), 7α,12α,13β-trihydroxyabiet-8(14)-en-18-oic acid (9), and abiet-8(14)-en-7α,12α,13β,15,18-pentaol (10) were isolated from the CHCl3 extract of the cones of Larix kaempferi. Their structures were determined on the basis of chemical and spectral evidence. The inhibitory effects of compounds 1-4 and 7-9 on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA), were examined for a primary screening for anti-tumor promotors. Key words: Larix kaempferi, Pinaceae, cones, abietane, EBV-EA.


1990 ◽  
Vol 17 (1) ◽  
pp. 49-54 ◽  
Author(s):  
Mitsuru Furukawa ◽  
Hideo Sakashita ◽  
Michihiro Kamide ◽  
Ryozo Umeda

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