scholarly journals EFFECTS OF RESERPINE AND DESIPRAMINE ON THE UPTAKE AND SUBCELLULAR DISTRIBUTION OF 5-HYDROXYTRYPTAMINE IN RABBIT BRAIN STEM AFTER INTRAVENOUS ADMINISTRATION OF 5-HYDROXYTRYPTOPHAN

1970 ◽  
Vol 20 (1) ◽  
pp. 87-91 ◽  
Author(s):  
TOMIO SEGAWA
1970 ◽  
Vol 66 (4) ◽  
pp. 400-407 ◽  
Author(s):  
Tomio SEGAWA ◽  
Isami KURUMA ◽  
Katsuya TAKATSUKA ◽  
Hiroshi TAKAGI

1979 ◽  
Vol 187 (1) ◽  
pp. 199-243 ◽  
Author(s):  
David L. Felten ◽  
John P. Cummings

1986 ◽  
Vol 66 (2) ◽  
pp. 563-565
Author(s):  
C. A. KELLKHER ◽  
M. IVAN

The effect of a single intravenous dose of 0, 50 or 100 g molybdenum (Mo) as [99Mo] labelled sodium tetrathiomolybdate (Na2MoS4) on the subcellular distribution of copper (Cu) in the liver was studied in three groups of four sheep. The sheep received a 35-mg intravenous dose of Cu 20 h prior, and were killed 24 h after the dosing with Mo. Subcellular fractionation of liver homogenates revealed that [Formula: see text] may react with Cu in the nuclear (lysosomal) fraction. Key words: Sheep, copper, molybdenum, tetrathiomolybdate, liver fractions


1967 ◽  
Vol 105 (2) ◽  
pp. 831-835 ◽  
Author(s):  
J. W. Ridge

1. The respiratory rates in vitro of ten structures of the rabbit brain were measured in the presence of a normal (5mm) and an elevated (50mm) concentration of K+ ions. The results were expressed on a dry-weight basis and in terms of cell density. 2. On a dry-weight basis, with a normal concentration of K+, there was a steady decrease in respiratory rate on passing from the cerebral cortex through successively lower centres to the brain-stem, i.e. respiration was negatively correlated with phylogenetic age. 3. When the resting respiratory rates were expressed in terms of cell density there was no correlation with phylogenetic age. The neuron-containing structures of the cerebrum and brain-stem had identical respiratory rates with the exception of the cerebral cortex which had a higher rate. 4. The K+-stimulated respiratory rates/cell also showed a negative correlation with phylogenetic age; the higher centres responded with a greater percentage increase than the lower. 5. The results from the cerebellar cortex were anomalous. 6. There were variations of respiratory rate within the diencephalon. The thalamus had a relatively high respiratory rate, the anterior and ventral regions relatively low and the hypothalamus intermediate. 7. The oxygen consumption of white matter was not increased by a high external concentration of K+.


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