scholarly journals The Structure of the Cyclodextrin Complex. V. Crystal Structures of α-Cyclodextrin Complexes withp-Nitrophenol andp-Hydroxybenzoic Acid

1977 ◽  
Vol 50 (6) ◽  
pp. 1416-1424 ◽  
Author(s):  
Kazuaki Harata
1997 ◽  
Vol 75 (1) ◽  
pp. 52-55 ◽  
Author(s):  
Frank Hacket ◽  
Jose-Miguel Coteron ◽  
Hans-Jörg Schneider ◽  
Vladimir P. Kazachenko

Equilibrium constants of complexes between β-cyclodextrin and glucose, galactose, or mannose have been determined by fluorometric competition titrations in water to be as low as K = 1 – 0.5 M−1, in sharp contrast to recently published values for glucose around K = 400 M–1. The pentoses ribose, xylose, and arabinose show association constants between 6.3 and 1.5 M−1, in agreement with published values. Preliminary computer-aided molecular modelling studies suggest that the small values observed for the hexoses are not due to steric hindrance of an intracavity inclusion but to a smaller number of intermolecular hydrogen bonds and to some strain as a result of cyclodextrin deformation. Calorimetric measurements of the glucose–β-cyclodextrin complex show, again in contradiction with the literature, an endothermic reaction, or a free enthalpy value close to zero. Key words: cyclodextrin complexes, sugar complexation, glucose complexation, calorimetry, computer-aided molecular modelling.


RSC Advances ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 3450-3458 ◽  
Author(s):  
Joo Hyung Lee ◽  
Sang Ho Park ◽  
Seong Hun Kim

Bio-polyurethane nanofibers containing triclosan–cyclodextrin complexes to enhance antibacterial properties were prepared using an electrospinning method.


1999 ◽  
Vol 320 (3-4) ◽  
pp. 261-266 ◽  
Author(s):  
Shin Muraoka ◽  
Osamu Matsuzaka ◽  
Shigehiro Kamitori ◽  
Kenji Okuyama

Author(s):  
Gerhard Laus ◽  
Volker Kahlenberg ◽  
Thomas Gelbrich ◽  
Sven Nerdinger ◽  
Herwig Schottenberger

Mutual carboxyl–carboxyl O—H...O hydrogen bonds link the molecules of the title compound, C7H5BrO3, into centrosymmetric dimers which display a centralR22(8) ring motif. In addition, there is an intramolecular hydroxyl–carboxyl O—H...O interaction present. A comparison with the crystal structures of 59 other substituted derivatives of salicylic acid shows that both the centrosymmetric carboxyl–carboxyl O—H...O dimer and the stacking mode of molecules along the shortaaxis observed in the title structure are frequent packing motifs in this set.


2012 ◽  
Vol 188 ◽  
pp. 70-75 ◽  
Author(s):  
Monica Cretan Stamate ◽  
Carmen Gafitanu ◽  
Ciprian Stamate ◽  
Eliza Gafitanu

Since, anti-inflamatory drugs have a high demand due to increased incidence of pain associated with different pathology; the objectives of this paper are the synthesis, the physicochemical characterization and analysis of the tribological properties for the ketoprofen-cyclodextrin complexes. The analysis of solubility for these complexes was carried out using MathCAD software. Tribological factors were evaluated by the wear resistance of cylindrical tablets containing ketoprofen-cyclodextrin complex, methocel and magnesium stearate. The tablets with ketoprofen-cyclodextrin complexes provide good solubility and wear resistance and these are ideal for preparation of extended release systems like implantable tablets or for orally administration tablets.


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