scholarly journals Fabrication of bio-based polyurethane nanofibers incorporated with a triclosan/cyclodextrin complex for antibacterial applications

RSC Advances ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 3450-3458 ◽  
Author(s):  
Joo Hyung Lee ◽  
Sang Ho Park ◽  
Seong Hun Kim
Keyword(s):  
Antibacterial Properties ◽  
Cyclodextrin Complexes ◽  
Cyclodextrin Complex ◽  
Electrospinning Method

Bio-polyurethane nanofibers containing triclosan–cyclodextrin complexes to enhance antibacterial properties were prepared using an electrospinning method.

The complexation of glucose and other monosaccharides with cyclodextrins

1997 ◽  
Vol 75 (1) ◽  
pp. 52-55 ◽  
Author(s):  
Frank Hacket ◽  
Jose-Miguel Coteron ◽  
Hans-Jörg Schneider ◽  
Vladimir P. Kazachenko
Keyword(s):  
Molecular Modelling ◽  
Equilibrium Constants ◽  
Association Constants ◽  
Cyclodextrin Complexes ◽  
Cyclodextrin Complex ◽  
Intermolecular Hydrogen Bonds ◽  
Calorimetric Measurements ◽  
Computer Aided ◽  
Molecular Modelling Studies ◽  
Modelling Studies

Equilibrium constants of complexes between β-cyclodextrin and glucose, galactose, or mannose have been determined by fluorometric competition titrations in water to be as low as K = 1 – 0.5 M−1, in sharp contrast to recently published values for glucose around K = 400 M–1. The pentoses ribose, xylose, and arabinose show association constants between 6.3 and 1.5 M−1, in agreement with published values. Preliminary computer-aided molecular modelling studies suggest that the small values observed for the hexoses are not due to steric hindrance of an intracavity inclusion but to a smaller number of intermolecular hydrogen bonds and to some strain as a result of cyclodextrin deformation. Calorimetric measurements of the glucose–β-cyclodextrin complex show, again in contradiction with the literature, an endothermic reaction, or a free enthalpy value close to zero. Key words: cyclodextrin complexes, sugar complexation, glucose complexation, calorimetry, computer-aided molecular modelling.

The Characterization of Ketoprofen-Hydroxypropyl–β-Cyclodextrin Complex with Modified Drugs Release Properties

2012 ◽  
Vol 188 ◽  
pp. 70-75 ◽  
Author(s):  
Monica Cretan Stamate ◽  
Carmen Gafitanu ◽  
Ciprian Stamate ◽  
Eliza Gafitanu
Keyword(s):  
Wear Resistance ◽  
Extended Release ◽  
Physicochemical Characterization ◽  
Magnesium Stearate ◽  
Cyclodextrin Complexes ◽  
High Demand ◽  
Cyclodextrin Complex ◽  
Good Solubility ◽  
Mathcad Software

Since, anti-inflamatory drugs have a high demand due to increased incidence of pain associated with different pathology; the objectives of this paper are the synthesis, the physicochemical characterization and analysis of the tribological properties for the ketoprofen-cyclodextrin complexes. The analysis of solubility for these complexes was carried out using MathCAD software. Tribological factors were evaluated by the wear resistance of cylindrical tablets containing ketoprofen-cyclodextrin complex, methocel and magnesium stearate. The tablets with ketoprofen-cyclodextrin complexes provide good solubility and wear resistance and these are ideal for preparation of extended release systems like implantable tablets or for orally administration tablets.

Composited Silver-Contained PA 6 Electrospun Fibers with Spunbond Nonwovens for Filtration Applications

2011 ◽  
Vol 287-290 ◽  
pp. 2626-2629 ◽  
Author(s):  
Yi Jun Pan ◽  
Wei Sheng Chuang ◽  
Chao Yu Lin ◽  
Chun Hua Chu
Keyword(s):  
Electrospun Fiber ◽  
Antibacterial Properties ◽  
Silver Ions ◽  
Polyamide 6 ◽  
Filtration Efficiency ◽  
Electrospun Fibers ◽  
Silver Particles ◽  
Filter Media ◽  
Electrospinning Method ◽  
Composite Filter

By using electrospinning method, polyamide 6 (PA 6) nanofibers containing 1 wt% of AgNo3 were spun from different concentrations solutions (15-25 wt%) for use as composite filter media. The silver ions in PA 6 nanofibers were reduced by ascorbic acid solution to silver particles offering antibacterial properties to the final filter after electrospinning. The results show, fibers with mean diameters less than 160 nm were prepared for use as filter media by electrospinning. The diameter of electrospun fiber was proportioned to the viscosity of PA 6 solution but was inversed to the applied electrical voltage. The viscosities of PA 6 solution were decreased by adding of AgNo3 from which brought more irregular formation of electrospun fibers. The filtration efficiency of spunbond nonwoven would improve greatly by compositing the electrospun PA6 web with or without silver.

Antimicrobial Electrospun Nanofibrous Mat Based on Essential Oils for Biomedical Applications

2020 ◽  
Vol 20 (9) ◽  
pp. 5376-5380
Author(s):  
Ji Yeon Lee ◽  
Deockhee Yoon ◽  
Byeong Cheol Son ◽  
Abdelrahman I. Rezk ◽  
Chan Hee Park ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Biomedical Applications ◽  
Control Sample ◽  
Antibacterial Properties ◽  
Test Methods ◽  
Test Items ◽  
Electrospinning Method ◽  
Antibacterial Evaluation

Polyurethane (PU) nanofibers containing three different essential oils (teatree, cinnamon bark, clove) were produced by electrospinning method. Morphology of the electrospun nanofibrous was studied using Field Emission Scanning Electron Microscope (FE-SEM). We were studying to reveal that different concentration of essential oil display different mechanical properties for the nanofibrous mat. The antibacterial properties of the nanofibrous loaded with the essential oil were studied quantitatively and qualitatively using three strains (Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa). The antibacterial evaluation showed higher antibacterial activity for nanofibrous loaded with essential oil compares to control sample. In vitro cell culture were proceed to confirm biocompatibility of the nanofibrous contained essential oils. In this study, we present a comparison of the samples for each of the experiment based on the derived test items and test methods. The results of this study demonstrate that the proposed nanofibrous mat loaded with essential oil will be a promising future material for different biomedical applications.

scholarly journals Polyacrylonitrile Nanofibers Containing Viroblock as Promising Material for Protective Clothing

2021 ◽  
Vol 11 (23) ◽  
pp. 11469
Author(s):  
Mujtaba Hussain ◽  
Abdul Salam ◽  
Muhammad Fahad Arain ◽  
Azeem Ullah ◽  
Anh-Tuan Dao ◽  
...  
Keyword(s):  
Thermogravimetric Analysis ◽  
Protective Clothing ◽  
Composite Nanofibers ◽  
Antibacterial Properties ◽  
Silver Ions ◽  
Lipid Vesicle ◽  
Infectious Agents ◽  
Bactericidal Property ◽  
Water Contact ◽  
Electrospinning Method

Antimicrobial viroblock/polyacrylonitrile nanofiber webs fabricated using the electrospinning method were assessed in terms of the antimicrobial activity against infectious agents as a potential material used in mask production. Viroblock (VB) is an amalgam of lipid vesicle and silver. Lipid vesicle depletes the virus outer membrane, which contains cholesterol, while silver ions penetrate the virus, interact with sulfur-bearing moieties, and possess the virus bactericidal property. VB, having anti-coronavirus and anti-influenza properties, was prepared in four different concentrations, 0.5 wt%, 1 wt%, 1.5 wt%, and 2 wt%, in regard to nanofiber weight. The resultant nanofibers were characterized by scanning electron microscope (SEM), Fourier transform infrared (FTIR), thermogravimetric analysis (TGA), water contact angle, water content, and thermogravimetric analysis (TGA). Moreover, all nanofibrous samples were evaluated for cell proliferation assay and ATCC antibacterial tests. Based on characterization results and cytotoxicity, the developed composite nanofibers-based webs showed good promise for utilization in anti-viral masks. Particularly, 2 wt% VB/PAN nanofibers have the highest antibacterial properties against negative and positive bacteria along with excellent cell viability.

scholarly journals Biopolymers for Biomedical and Pharmaceutical Applications: Recent Advances and Overview of Alginate Electrospinning

Nanomaterials ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 404 ◽  
Author(s):  
Jolanta Wróblewska-Krepsztul ◽  
Tomasz Rydzkowski ◽  
Iwona Michalska-Pożoga ◽  
Vijay Kumar Thakur
Keyword(s):  
Antibacterial Properties ◽  
Electrospinning Process ◽  
Fiber Formation ◽  
Biologically Active ◽  
Food Sector ◽  
Natural Substances ◽  
Pharmaceutical Applications ◽  
Recent Advances ◽  
Electrospinning Method ◽  
Nanofiber Mats

Innovative solutions using biopolymer-based materials made of several constituents seems to be particularly attractive for packaging in biomedical and pharmaceutical applications. In this direction, some progress has been made in extending use of the electrospinning process towards fiber formation based on biopolymers and organic compounds for the preparation of novel packaging materials. Electrospinning can be used to create nanofiber mats characterized by high purity of the material, which can be used to create active and modern biomedical and pharmaceutical packaging. Intelligent medical and biomedical packaging with the use of polymers is a broadly and rapidly growing field of interest for industries and academia. Among various polymers, alginate has found many applications in the food sector, biomedicine, and packaging. For example, in drug delivery systems, a mesh made of nanofibres produced by the electrospinning method is highly desired. Electrospinning for biomedicine is based on the use of biopolymers and natural substances, along with the combination of drugs (such as naproxen, sulfikoxazol) and essential oils with antibacterial properties (such as tocopherol, eugenol). This is a striking method due to the ability of producing nanoscale materials and structures of exceptional quality, allowing the substances to be encapsulated and the drugs/ biologically active substances placed on polymer nanofibers. So, in this article we briefly summarize the recent advances on electrospinning of biopolymers with particular emphasis on usage of Alginate for biomedical and pharmaceutical applications.

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