An efficient computer-aided hyperspectral imaging system and its biomedical applications

2015 ◽  
pp. 147-152
Sensors ◽  
2019 ◽  
Vol 19 (7) ◽  
pp. 1692 ◽  
Author(s):  
José A. Gutiérrez-Gutiérrez ◽  
Arturo Pardo ◽  
Eusebio Real ◽  
José M. López-Higuera ◽  
Olga M. Conde

Prototyping hyperspectral imaging devices in current biomedical optics research requires taking into consideration various issues regarding optics, imaging, and instrumentation. In summary, an ideal imaging system should only be limited by exposure time, but there will be technological limitations (e.g., actuator delay and backlash, network delays, or embedded CPU speed) that should be considered, modeled, and optimized. This can be achieved by constructing a multiparametric model for the imaging system in question. The article describes a rotating-mirror scanning hyperspectral imaging device, its multiparametric model, as well as design and calibration protocols used to achieve its optimal performance. The main objective of the manuscript is to describe the device and review this imaging modality, while showcasing technical caveats, models and benchmarks, in an attempt to simplify and standardize specifications, as well as to incentivize prototyping similar future designs.


LWT ◽  
2021 ◽  
Vol 138 ◽  
pp. 110678
Author(s):  
Irina Torres ◽  
Dolores Pérez-Marín ◽  
Miguel Vega-Castellote ◽  
María-Teresa Sánchez

Micromachines ◽  
2020 ◽  
Vol 11 (9) ◽  
pp. 861
Author(s):  
Elizabeth E. Niedert ◽  
Chenghao Bi ◽  
Georges Adam ◽  
Elly Lambert ◽  
Luis Solorio ◽  
...  

A microrobot system comprising an untethered tumbling magnetic microrobot, a two-degree-of-freedom rotating permanent magnet, and an ultrasound imaging system has been developed for in vitro and in vivo biomedical applications. The microrobot tumbles end-over-end in a net forward motion due to applied magnetic torque from the rotating magnet. By turning the rotational axis of the magnet, two-dimensional directional control is possible and the microrobot was steered along various trajectories, including a circular path and P-shaped path. The microrobot is capable of moving over the unstructured terrain within a murine colon in in vitro, in situ, and in vivo conditions, as well as a porcine colon in ex vivo conditions. High-frequency ultrasound imaging allows for real-time determination of the microrobot’s position while it is optically occluded by animal tissue. When coated with a fluorescein payload, the microrobot was shown to release the majority of the payload over a 1-h time period in phosphate-buffered saline. Cytotoxicity tests demonstrated that the microrobot’s constituent materials, SU-8 and polydimethylsiloxane (PDMS), did not show a statistically significant difference in toxicity to murine fibroblasts from the negative control, even when the materials were doped with magnetic neodymium microparticles. The microrobot system’s capabilities make it promising for targeted drug delivery and other in vivo biomedical applications.


2018 ◽  
Vol 11 (1) ◽  
Author(s):  
Xuping Feng ◽  
Chenliang Yu ◽  
Xiaodan Liu ◽  
Yunfeng Chen ◽  
Hong Zhen ◽  
...  

Author(s):  
Hyeong-Geun Yu ◽  
Whimin Kim ◽  
Dong-Jo Park ◽  
Dong Eui Chang ◽  
Hyunwoo Nam

2018 ◽  
Vol 8 (12) ◽  
pp. 2602 ◽  
Author(s):  
Laurence Schimleck ◽  
Joseph Dahlen ◽  
Seung-Chul Yoon ◽  
Kurt Lawrence ◽  
Paul Jones

Near-infrared (NIR) spectroscopy and NIR hyperspectral imaging (NIR-HSI) were compared for the rapid estimation of physical and mechanical properties of No. 2 visual grade 2 × 4 (38.1 mm by 88.9 mm) Douglas-fir structural lumber. In total, 390 lumber samples were acquired from four mills in North America and destructively tested through bending. From each piece of lumber, a 25-mm length block was cut to collect diffuse reflectance NIR spectra and hyperspectral images. Calibrations for the specific gravity (SG) of both the lumber (SGlumber) and 25-mm block (SGblock) and the lumber modulus of elasticity (MOE) and modulus of rupture (MOR) were created using partial least squares (PLS) regression and their performance checked with a prediction set. The strongest calibrations were based on NIR spectra; however, the NIR-HSI data provided stronger predictions for all properties. In terms of fit statistics, SGblock gave the best results, followed by SGlumber, MOE, and MOR. The NIR-HSI SGlumber, MOE, and MOR calibrations were used to predict these properties for each pixel across the transverse surface of the scanned samples, allowing SG, MOE, and MOR variation within and among rings to be observed.


Author(s):  
Qiao Jun ◽  
Michael Ngadi ◽  
Ning Wang ◽  
Aynur Gunenc ◽  
Mariana Monroy ◽  
...  

Pork quality is usually determined subjectively as PSE, PFN, RFN, RSE and DFD based on color, texture and exudation of the meat. In this study, a hyperspectral-imaging-based technique was developed to achieve rapid, accurate and objective assessment of pork quality. The principal component analysis (PCA) and stepwise operation methods were used to select feature waveband from the entire spectral wavelengths (430 to 980 nm). Then the feature waveband images were extracted at the selected feature wavebands from raw hyperspectral images, and the average reflectance (R) was calculated within the whole loin-eye area. Artificial neural network was used to classify these groups. Results showed that PCA analysis had a better performance than that of stepwise operation for feature waveband images selection. The 1st derivative data gave a better result than that of mean reflectance spectra data. The best classified result was 87.5% correction. The error frequency showed that RSE samples were easier to classify. The PFN and PSE samples were difficult to separate from each other.


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