Blood-Sugar Studies in Mental Disorders

1925 ◽  
Vol 71 (294) ◽  
pp. 443-473 ◽  
Author(s):  
S. A. Mann
Keyword(s):  
Mental Disorders ◽  
Carbohydrate Metabolism ◽  
Blood Sugar ◽  
General Paralysis ◽  
Common Experience

It is a common experience in the investigation of mental disorders that glycosuria is frequently found, thus indicating a tendency in such cases to a faulty carbohydrate metabolism. With the exception of epilepsy, this occurrence of glycosuria has been noted in most mental conditions. Intermittent glycosuria is met with in general paralysis (Kraepelin) (1); Bond (2) and Strauss (3) note it in about 10 per cent. of their cases. In dementia prócox Schultze and Knauer (4) did not observe glycosuria in the apathetic form of hebephrenia, but often found it to occur with catatonic excitement. With other observers (see Allers (5)) they record the marked association of glycosuria with depressed states, while its occurrence in mania was infrequent except in markedly excited and resistive cases.

BLOOD-SUGAR CURVES IN CERTAIN MENTAL DISORDERS.

The Lancet ◽  
1927 ◽  
Vol 209 (5409) ◽  
pp. 925-927 ◽  
Author(s):  
RoyN. Craig
Keyword(s):  
Mental Disorders ◽  
Blood Sugar

STUDIES OF CARBOHYDRATE METABOLISM IN THE NEWBORN INFANT

PEDIATRICS ◽  
1967 ◽  
Vol 40 (1) ◽  
pp. 69-77
Author(s):  
Rosita S. Pildes ◽  
Audrey E. Forbes ◽  
Marvin Cornblath
Keyword(s):  
Blood Glucose ◽  
Carbohydrate Metabolism ◽  
Birth Order ◽  
Blood Sugar ◽  
Newborn Infant

Blood sugar determinations were done during the first 5 days of life on 100 sets of twins. Hypoglycemia was found in the smaller member in 8 of 11 pairs who were discordant by more than 25% with the smaller twin weighing less than 2.0 kg. Hypoglycemia occurred in one other pair of the remaining 89 sets of twins. Blood glucose values were not influenced by the birth order or the sex of the infants. Infants who weighed over 2,500 gm had significantly higher blood sugars than those who weighed below 2,500 gm.

Effect of septacrol'u (acridine derivative) on blood sugar in various patients with normal carbohydrate metabolism and in diabetics

1929 ◽  
Vol 25 (5) ◽  
pp. 577-577
Author(s):  
Z. Blumstein
Keyword(s):  
Carbohydrate Metabolism ◽  
Blood Sugar ◽  
Acridine Derivative ◽  
The Right

Otto Jul Nielsen (Acta medica Scandinavica, Vol. LXX (1929), fase. 1) investigated the effect of septacrol'u (acridine derivative) on blood sugar in various patients with normal carbohydrate metabolism and in diabetics. Septacrol was administered intravenously at 5 kbp. with. In the first cases, the amount of sugar in the blood did not change, and secondly, it is true, there was some decrease, but in magnitude it did not exceed those figures that were obtained in the study of blood sugar in starving patients. These results give N'y the right to consider the action of septacrol to be sharply different from the action of insulin

Pyramidone action on carbohydrate metabolism

1934 ◽  
Vol 30 (7-8) ◽  
pp. 784-784
Author(s):  
G. Krause ◽  
H. Marx
Keyword(s):  
Carbohydrate Metabolism ◽  
Blood Sugar ◽  
High Fever

The accidental observation of a severely diabetic with furunculosis and high fever, where after giving pyramidon, in addition to a drop in t, a drop in blood sugar was observed for several days, served G. Krause and H. Marx the reason for a more detailed study of the action of Pyramidon, on healthy and diabetic persons.

Effects of Epinephrine on Carbohydrate Metabolism in Underfed and ad Libitum-Fed Rats

1957 ◽  
Vol 190 (2) ◽  
pp. 239-242
Author(s):  
B. N. Spirtos ◽  
R. G. Stuelke ◽  
N. S. Halmi
Keyword(s):  
Carbohydrate Metabolism ◽  
Blood Sugar ◽  
Blood Lactate ◽  
Liver Glycogen ◽  
Hepatic Glycogen ◽  
Commercial Diet ◽  
Ad Libitum ◽  
Sugar Levels ◽  
Fasted Rats

Rats fed 10 gm of a commercial diet for 4–5 weeks and fasted for 24 hours showed less rise in liver glycogen and blood sugar levels in response to the injection of epinephrine than did ad libitum-fed-fasted rats. Gastrocnemius glycogen levels were found to be higher in underfed-fasted animals and fell to the same extent as in ad libitum fed-fasted animals when epinephrine was given. Blood lactate concentrations, however, rose less markedly in the underfed-fasted group. This may have been at least partly responsible for the diminished rise in hepatic glycogen and blood sugar.

BIOBOARD

2018 ◽  
Vol 22 (03) ◽  
pp. 53-57
Keyword(s):  
Mental Disorders ◽  
Drug Development ◽  
Blood Sugar ◽  
Chronic Diseases ◽  
International Collaboration ◽  
Translational Medicine ◽  
Therapeutic Treatment ◽  
Bay Area ◽  
Multiple Chronic Diseases

ASIA – The first Greater Bay Area biotechnology and translational medicine international collaboration. ASIA – New insight on therapeutic treatment for mental disorders. OCEANIA – Multiple chronic diseases leave patients with adversely high costs. AMERICAS – Measuring the risks and rewards of drug development. AMERICAS – Ketone drink could help diabetics by lowering blood sugar.

Salivary Glucose Threshold

1958 ◽  
Vol 192 (3) ◽  
pp. 482-484 ◽  
Author(s):  
L. L. Langley ◽  
C. H. Gunthorpe ◽  
W. A. Beall
Keyword(s):  
Carbohydrate Metabolism ◽  
Blood Sugar ◽  
Blood Sugar Level ◽  
Fasting Blood Sugar ◽  
Parotid Saliva ◽  
Permeability Function ◽  
Diabetic Dogs ◽  
Glucose Threshold

There is no glucose in the parotid saliva of normal, untreated dogs. Glucose appears in the saliva when the blood sugar is elevated to about 512 mg%. If insulin is given along with the infusion of glucose, the threshold is elevated to approximately 1235 mg%. Conversely, in alloxan diabetic dogs there is glucose in the saliva at the fasting blood sugar level. In this series that level averaged 269 mg%. Apparently the passage of glucose from the blood to the saliva is more than a simple permeability function. Glandular intracellular carbohydrate metabolism may be involved.

The Diagnosis of Insanity

1857 ◽  
Vol 3 (20) ◽  
pp. 141-185
Author(s):  
John Charles Bucknill
Keyword(s):  
Mental Disorders ◽  
Mental Disorder ◽  
Large Class ◽  
Acute Mania ◽  
Mutual Dependence ◽  
General Paralysis ◽  
Moral Insanity

The Diagnosis of Mania — Melancholia — Monomania — Moral Insanity—General Paralysis—Feigned Insanity —Concealed InsanityMania is the term applied to that large class of mental disorders in which the functions are in a state of excitement, and their mutual dependence and proportion disturbed. It embraces forms of disease so widely apart from each other, that in treating practically of its diagnosis it will be essential to make some classification. For practical purposes it will be sufficient to distinguish its forms into those of acute mania, comprising cases which present recent and active symptoms; chronic mania, in which acute symptoms have given way to others of a more tranquil and permanent kind; and incomplete mania, corresponding to the “mania raisonante” of the French, and embracing those anomalous and undeveloped forms of mental disorder in which defective power of volition and morbid propensities are prominent symptoms.

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