scholarly journals Quantified visuospatial attention & motion processing in very preterm born children from 1y to 2y corrected age is related to neurodevelopmental outcome

2019 ◽  
Vol 19 (10) ◽  
pp. 57a
Author(s):  
Marlou JG Kooiker ◽  
Maud M van Gils ◽  
Irwin KM Reiss ◽  
Johannes van der Steen ◽  
Johan JM Pel
Author(s):  
Victoria A. A. Beunders ◽  
Marijn J. Vermeulen ◽  
Jorine A. Roelants ◽  
Nienke Rietema ◽  
Renate M. C. Swarte ◽  
...  

2019 ◽  
Author(s):  
Maria Feldmann ◽  
Valentin Rousson ◽  
Thi Dao Nguyen ◽  
Vera Bernet ◽  
Cornelia Hagmann ◽  
...  

AbstractAimTo analyse the association between early aEEG and cognitive outcome at early school-age in very preterm infants.MethodsProspective cohort study including infants with gestational age (GA) <32.0 weeks, undergoing continuous aEEG recording during first 4 days of life. Semiquantitative and quantitative (maximum/minimum amplitude) measures were averaged over the recording period. Cognitive outcome was assessed with the Kaufman-Assessment Battery for Children at 5 years of age. Uni- and multivariate logistic regressions were calculated between aEEG parameters and normal cognitive outcome (IQ≥85).ResultsAmong 118 monitored preterm children, 89 were assessed at median(IQR) corrected age of 68.6 months (65.5-71.2) [48% female, median(IQR) GA 29.9(28.2,30.9) weeks, mean(SD) birth weight 1235(363) grams]. Mean(SD) IQ was 97.8(12.7). IQ<85 occurred in 21.3 %, cerebral palsy was found in 3.4%. Despite univariate associations of total maturity scores, cycling subscores, background pattern and minimum aEEG amplitude with normal cognitive outcome none of the associations remained significant after adjustment for confounders. Socioeconomic status was identified as independent predictor of neurodevelopmental outcome.ConclusionIn this cohort of very preterm infants, early short-term aEEG was not predictive of later cognitive outcome. Further research is needed to explore how aEEG could help to inform long-term prognosis in this population group.Key notesPreterm born infants are at high risk for neurodevelopmental impairment.Early amplitude integrated electroencephalography characteristics are univariately associated with cognitive outcome at 5 years of age in preterm born children.However, socioeconomic factors and neonatal morbidity were stronger predictors of long-term neurodevelopmental outcome than early aEEG measures.


2013 ◽  
Vol 74 (5) ◽  
pp. 564-569 ◽  
Author(s):  
Ingrid Hansen-Pupp ◽  
Holger Hövel ◽  
Chatarina Löfqvist ◽  
Lena Hellström-Westas ◽  
Vineta Fellman ◽  
...  

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3409
Author(s):  
Lisa M. Hortensius ◽  
Els Janson ◽  
Pauline E. van van Beek ◽  
Floris Groenendaal ◽  
Nathalie H. P. Claessens ◽  
...  

Background: Determining optimal nutritional regimens in extremely preterm infants remains challenging. This study aimed to evaluate the effect of a new nutritional regimen and individual macronutrient intake on white matter integrity and neurodevelopmental outcome. Methods: Two retrospective cohorts of extremely preterm infants (gestational age <28 weeks) were included. Cohort B (n = 79) received a new nutritional regimen, with more rapidly increased, higher protein intake compared to cohort A (n = 99). Individual protein, lipid, and caloric intakes were calculated for the first 28 postnatal days. Diffusion tensor imaging was performed at term-equivalent age, and cognitive and motor development were evaluated at 2 years corrected age (CA) (Bayley-III-NL) and 5.9 years chronological age (WPPSI-III-NL, MABC-2-NL). Results: Compared to cohort A, infants in cohort B had significantly higher protein intake (3.4 g/kg/day vs. 2.7 g/kg/day) and higher fractional anisotropy (FA) in several white matter tracts but lower motor scores at 2 years CA (mean (SD) 103 (12) vs. 109 (12)). Higher protein intake was associated with higher FA and lower motor scores at 2 years CA (B = −6.7, p = 0.001). However, motor scores at 2 years CA were still within the normal range and differences were not sustained at 5.9 years. There were no significant associations with lipid or caloric intake. Conclusion: In extremely preterm born infants, postnatal protein intake seems important for white matter development but does not necessarily improve long-term cognitive and motor development.


1983 ◽  
Vol 58 (8) ◽  
pp. 598-604 ◽  
Author(s):  
A L Stewart ◽  
R J Thorburn ◽  
P L Hope ◽  
M Goldsmith ◽  
A P Lipscomb ◽  
...  

2019 ◽  
Vol 129 ◽  
pp. 45-51 ◽  
Author(s):  
Regula Everts ◽  
Corina G. Schöne ◽  
Ines Mürner-Lavanchy ◽  
Maja Steinlin

Sign in / Sign up

Export Citation Format

Share Document