scholarly journals IL-23 Expression in Stewart-Treves Syndrome: Two Case Reports and Immunohistochemical Investigation

2020 ◽  
Vol 13 (1) ◽  
pp. 462-467
Author(s):  
Saaya Yoshida ◽  
Taku Fujimura ◽  
Kentaro Ohuchi ◽  
Yumi Kambayashi ◽  
Yuichiro Segawa ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Immunohistochemical Staining ◽  
Penile Cancer ◽  
Case Reports ◽  
Radical Mastectomy ◽  
Lymph Edema ◽  
Immunohistochemical Investigation ◽  
Radical Dissection

Stewart-Treves syndrome (STS) is a rare cutaneous lymphangiosarcoma developing from chronic lymph edema as a consequence of radical mastectomy or surgical invasion of the groin for the treatment of cervical or penile cancer. Previous reports suggested possible mechanisms in the development of lymphangiosarcoma that correlate with the immunological background of STS patients. In this report, we described two cases of STS developing in patients who underwent radical dissection for cervical cancer, we employed immunohistochemical staining of IL-23 and IL-17.

scholarly journals Lymphoepithelioma-Like Carcinoma of the Breast: A Case Report Unveiling Several Clinical and Histopathological Challenges

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
Tarek Aridi ◽  
Mohamad Fawwaz ◽  
Ahmad Kassab ◽  
Marwan Bahmad ◽  
Faisal Houcheimi ◽  
...  
Keyword(s):  
Case Reports ◽  
Progesterone Receptors ◽  
Radical Mastectomy ◽  
Residual Tumor ◽  
Excisional Biopsy ◽  
Axillary Lymph ◽  
Tumor Type ◽  
Estrogen And Progesterone Receptors ◽  
Type Iv ◽  
Criteria For Diagnosis

Lymphoepithelioma-like carcinoma (LELC) of the breast is an extremely rare tumor type. Histologically, it mimics undifferentiated nasopharyngeal carcinoma by demonstrating nests of neoplastic epithelial cells in a background of lymphoplasmacytic infiltrates. This paper reports a 62-year-old female patient with a 3 × 1.5 cm BI-RADS type IV breast mass diagnosed on excisional biopsy as LELC. The tumor is negative for estrogen and progesterone receptors and did not overexpress HER2/neu. Routine tests for clearance before surgery were performed, and patient was managed by a modified radical mastectomy with axillary lymph node dissection showing no residual tumor. Surgical CAse REports (SCARE) guidelines were followed for reporting our case. The rarity of LELC of the breast warrants the establishment and implementation of well-defined guidelines and criteria for diagnosis and management.

Immunohistochemical Investigation of Axillary Lymph Nodes for Micrometastases in Patients with Breast Cancer Using E29

1989 ◽  
Vol 75 (6) ◽  
pp. 563-565 ◽  
Author(s):  
Antonio Cavaliere ◽  
Brunangelo Falini ◽  
Giacomo Antonini
Keyword(s):  
Breast Cancer ◽  
Monoclonal Antibody ◽  
Epithelial Cells ◽  
Lymph Nodes ◽  
Histological Examination ◽  
Mammary Carcinoma ◽  
Radical Mastectomy ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Immunohistochemical Investigation

The axillary lymph nodes from 31 mammary carcinoma patients who had undergone radical mastectomy and were negative for metastases at routine histologic examination of hilar sections, were investigated with E29, an anti-epithelial monoclonal antibody, to detect the presence of neoplastic epithelial cells. In 4 of 433 lymph nodes examined (0.9 %) this antibody revealed the presence of epithelial metastatic foci which had not been observed at routine histological examination or interpreted as histiocytes. The 4 lymph nodes belonged to 4 different patients.

scholarly journals Secondary uterine carcinosarcoma after concurrent chemoradiotherapy for cervical cancer: Case reports

2017 ◽  
Vol 21 ◽  
pp. 81-83
Author(s):  
Akihiko Wakayama ◽  
Wataru Kudaka ◽  
Tadaharu Nakasone ◽  
Yusuke Taira ◽  
Yoichi Aoki
Keyword(s):  
Cervical Cancer ◽  
Concurrent Chemoradiotherapy ◽  
Case Reports ◽  
Cancer Case ◽  
Uterine Carcinosarcoma ◽  
Cervical Cancer Case

scholarly journals Septic Arthritis of the Hip Joint in Cervical Cancer Patients after Radiotherapy: Three Case Reports

2001 ◽  
Vol 9 (2) ◽  
pp. 41-45 ◽  
Author(s):  
Shu-Hua Yang ◽  
Rong-Sen Yang ◽  
Chin-Lin Tsai
Keyword(s):  
Cervical Cancer ◽  
Femoral Head ◽  
Septic Arthritis ◽  
Cancer Patients ◽  
Hip Joint ◽  
Defense Mechanisms ◽  
Case Reports ◽  
Causative Organism ◽  
Total Hip ◽  
Hip Arthroplasties

Cervical cancer patients may experience hip problems related to the cancer itself or therapeutic management for the cancer. Septic arthritis should be one of the possibilities but there have been no reports on this. Here we present three patients who developed hip problems more than two years after radiotherapy with or without a radical operation. One patient was managed as septic arthritis because of significant inflammatory signs around the affected hip joint even though the causative organism was not confirmed. Succeeding total hip arthroplasty functioned well and had no recurrence of infection. The hip problems of the other two patients were diagnosed as radiation osteonecrosis of the femoral head initially. However, Bacteroides fragilis infection was found several months after total hip arthroplasties. Radiotherapy to the pelvis may damage the hip joint and compromise host-defense mechanisms of the pelvic region. Both factors may increase the possibility of infection of hip joints. Further clinical evidence is needed to understand whether subacute or chronic anaerobic infection could also be one of the causes leading to progressive destruction of the femoral head.

scholarly journals Complete remission of relapsed cervical cancer through immunochemoradiotherapy: Two case reports and three proposed mechanism

2016 ◽  
Vol 5 (3) ◽  
pp. 127-131
Author(s):  
Yi-Hao Lin ◽  
Hsin-Hong Kuo ◽  
Ling-Hong Tseng ◽  
Jian-Tai Qiu ◽  
Fu-Shun Chang ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Complete Remission ◽  
Case Reports

scholarly journals Case Report: Solitary Extramedullary Plasmacytoma in the Cervix Misdiagnosed as Cervical Cancer

2021 ◽  
Vol 11 ◽  
Author(s):  
Ji Wang ◽  
Lin Jiang ◽  
Xuejin Ma ◽  
Tingchao Li ◽  
Heng Liu ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Case Reports ◽  
Extramedullary Plasmacytoma ◽  
Benign Tumors ◽  
Solitary Plasmacytoma ◽  
Imaging Findings ◽  
Mri Imaging ◽  
Cervical Lesions ◽  
Imaging Characteristics ◽  
Solitary Extramedullary Plasmacytoma

Solitary plasmacytoma (SP) is a malignant tumor caused by the monoclonal proliferation of plasma cells, representing less than 5% of plasma cell tumors. SP can be categorized into two groups: solitary bone plasmacytoma (SBP) and solitary extramedullary plasmacytoma (SEP). SEP most commonly occurs in the head and neck and is rarely located in the reproductive system. Here, we report a case of a 77-year-old woman with SEP in the cervix who had a 7-day history of vaginal bleeding. Ultrasonography and magnetic resonance imaging (MRI) showed an oval mass in the cervix, which was initially considered as neoplastic lesions and highly suspected to be cervical cancer, but cervical leiomyoma and other benign tumors cannot be completely excluded. Subsequently, cervical biopsy showed that the tumor was SEP, and then the patient underwent surgery. The postoperative pathological diagnosis was also SEP, which confirmed the radiologist’s misjudgment. In conclusion, SEP that occurs in the cervix is remarkably rare, and only nine cases have been reported in the cervix. No case reports to date have described in detail the imaging findings of cervical SEP. This study demonstrates the MRI imaging characteristics of a patient with SEP of the cervix and reviews the imaging findings of SEP reported in the previous literature, in order to provide more extensive insights for radiologists to consider the differential diagnosis of cervical lesions.

scholarly journals PHYLLODES TUMORS OF THE BREAST: 3 CASE REPORTS WITH DYNAMIC MRI AND IMMUNOHISTOCHEMICAL STAINING

2004 ◽  
Vol 65 (8) ◽  
pp. 2077-2082
Author(s):  
Masato FUJIYOSHI ◽  
Masato TAKAHASHI ◽  
Kazunori TAGUCHI ◽  
Hiromasa TAKAHASHI ◽  
Tomoo ITO ◽  
...  
Keyword(s):  
Immunohistochemical Staining ◽  
Case Reports ◽  
Dynamic Mri ◽  
Phyllodes Tumors

scholarly journals Carcinosarcoma of the Cervix: A Case Report

2021 ◽  
Vol 59 (240) ◽  
Author(s):  
Birendra Bhagat ◽  
Bijaya Chandra Aacharya ◽  
Sarita Gurung ◽  
Ranjan Raj Bhatta ◽  
Aasiya Rajbhandari
Keyword(s):  
Cervical Cancer ◽  
Cervical Carcinoma ◽  
Case Reports ◽  
Immunohistochemical Analysis ◽  
Abdominal Hysterectomy ◽  
Primary Treatment ◽  
Resected Specimen ◽  
Sarcomatous Component ◽  
Common Cause ◽  
Cervical Biopsy

Cervical carcinoma is the most common cause of mortality due to cancer in Nepal. Carcinosarcoma is a very rare subtype of cervical cancer which is characterized by the presence of both epithelial and mesenchymal malignant component. It constitutes less than 1% of cervical carcinoma. Due to the low occurrence of the disease, most of the data on treatment and prognosis are based on case reports and series. Here, we report a case of 69 years, female with cervical cancer (FIGO IIA2). Histopathological and immunohistochemical analysis of cervical biopsy initially showed primary adenosarcoma of the cervix. The tumor was non-responsive to primary treatment with concurrent chemoradiation. Later she was treated with abdominal hysterectomy and bilateral salpingo-oophorectomy. The final histopathology of the resected specimen showed a sarcomatous component along with carcinomatous changes in the endocervical glands favouring the diagnosis of carcinosarcoma of the cervix.

Incidence of metastasis in circumflex iliac nodes in patients with cervical cancer: a systematic review

2021 ◽  
pp. ijgc-2021-003005
Author(s):  
David Viveros-Carreño ◽  
Juliana Rodriguez ◽  
Rene Pareja
Keyword(s):  
Systematic Review ◽  
Cervical Cancer ◽  
Lymph Node ◽  
English Language ◽  
Early Stage ◽  
Case Reports ◽  
Pelvic Lymphadenectomy ◽  
Positive Lymph Node ◽  
Cochrane Central Register ◽  
Early Stage Disease

ObjectiveThe circumflex iliac nodes distal to the external iliac nodes are frequently removed when bilateral pelvic lymphadenectomy is performed in patients with cervical cancer. The objective of this systematic review was to assess the incidence of metastasis in the circumflex iliac nodes in patients with cervical cancer.MethodsPubMed/Medline, ClinicalTrials, Embase, Cochrane Central Register of Controlled Trials, Scopus, and Ovid databases were searched from inception to May 2021. We included articles published in English language reporting all types of studies, except for case reports and commentaries. Abstracts and unpublished studies were excluded. The inclusion criteria were diagnosis of cervical cancer, FIGO 2009 stages IA–IIB, squamous cell carcinoma, adenocarcinoma or adenosquamous carcinoma, and primary surgery including pelvic lymph node dissection.ResultsA total of 3037 articles were identified. Overall, 1165 eligible patients from four studies were included in the analysis. A total of 696 (59.7%) patients had early-stage disease (FIGO 2009 stages IA, IB1, IIA1). The median number of extracted circumflex iliac nodes, which was reported in two studies, was one (range not reported) and three (range 1–13). The positive lymph node rate for the entire population and circumflex iliac node involvement were 26.9% and 3.1%, respectively. Isolated metastases were reported for 904 patients (three studies) and in one patient nodal spread was detected (0.11%).ConclusionThe rate of isolated metastases in circumflex iliac nodes is small and excision of these lymph nodes as part of routine lymphadenectomy should be avoided.

scholarly journals Choroid Metastasis in a Patient with Squamous Cell Carcinoma of the Uterine Cervix: A Case Report

2020 ◽  
Vol 11 (3) ◽  
pp. 630-638
Author(s):  
Ángel García Vásquez ◽  
Gabriela Thomassiny Bautista ◽  
María José Sardá Ramirez ◽  
Janet Amelia Moheno Lozano ◽  
Oscar Solorzano Enriquez ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Squamous Cell Carcinoma ◽  
Uterine Cervix ◽  
Case Reports ◽  
Serous Retinal Detachment ◽  
Advanced Stage ◽  
Choroidal Metastasis ◽  
History Of ◽  
Ocular Metastasis ◽  
Rule Out

We present the case of a 43-year-old woman with unilateral loss of vision who had a history of cervical cancer, staged as FIGO IIIB, and who had undergone previous chemotherapy and radiotherapy, but was not a surgical candidate. An examination revealed serous retinal detachment with an underlying choroidal mass in the left eye. We reviewed all available published case reports of uterine cervix metastases to the eye and adnexa and compiled all information into a table to present clinical and epidemiological findings. Unilateral choroidal metastasis arising from cervical cancer is extremely rare. In most cases, a history of cervical carcinoma is confirmed in the advanced stage of the disease. Ocular metastasis may be the presenting feature of primary cervical malignancy; therefore, to rule out malignancy in every woman who develops these clinical features, a cervical examination should be included in the workup.

Sign in / Sign up

Export Citation Format

Share Document