scholarly journals Complete remission of relapsed cervical cancer through immunochemoradiotherapy: Two case reports and three proposed mechanism

2016 ◽  
Vol 5 (3) ◽  
pp. 127-131
Author(s):  
Yi-Hao Lin ◽  
Hsin-Hong Kuo ◽  
Ling-Hong Tseng ◽  
Jian-Tai Qiu ◽  
Fu-Shun Chang ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Complete Remission ◽  
Case Reports

scholarly journals Expression of DNA damage response proteins and complete remission after radiotherapy of stage IB–IIA of cervical cancer

2006 ◽  
Vol 94 (11) ◽  
pp. 1683-1689 ◽  
Author(s):  
C Beskow ◽  
L Kanter ◽  
Å Holgersson ◽  
B Nilsson ◽  
B Frankendal ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Dna Damage ◽  
Complete Remission ◽  
Dna Damage Response ◽  
Stage Ib ◽  
Damage Response

scholarly journals Neoadjuvant Chemotherapy Consisting of Cisplatin and Nab-paclitaxel Improves the Complete Remission Rate of Locally Advanced Cervical Cancer Patients

2021 ◽  
Author(s):  
Xiao-Li Yu ◽  
Miao-Fang Wu ◽  
Lin Ding ◽  
Jin Yang ◽  
Shou-Min Bai
Keyword(s):  
Cervical Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Complete Remission ◽  
Concurrent Chemoradiotherapy ◽  
Remission Rate ◽  
Locally Advanced ◽  
Control Group ◽  
Advanced Cervical Cancer ◽  
External Radiotherapy ◽  
Locally Advanced Cervical Cancer

Abstract Background: This study was aimed to determine the effect of neoadjuvant chemotherapy consisting of nab-paclitaxel and cisplatin (NACT-nPC) in patients with locally advanced cervical cancer.Materials and Methods: The consecutive, newly diagnosed, non-metastatic and locally advanced cervical cancer patients were retrospectively recruited between October 2016 and June 2020 in our hospital. All patients received concurrent chemoradiotherapy alone or following neoadjuvant chemotherapy. Patients were divided into two groups: one receiving NACT-nPC, and the control group receiving no or other regimes of neoadjuvant chemotherapy. We compared the complete remission rate of primary tumor at the end of external radiotherapy and chemoradiotherapy between the two groups. Results: A total of 198 patients were enrolled in this study, including 60 in NACT-nPC group and 138 in control group. At the end of external radiotherapy, 27 patients in NACT-nPC group and 32 patients in control group achieved complete remission (P = 0.002). At the end of chemoradiotherapy, 56 patients in NACT-nPC group and 114 patients in control group achieved complete remission (P = 0.033). The acute side effects above grade 3 in NACT-nPC group was 41.7% (25/60) and manageable, lower than control group which was 77/138 (55.8%).Conclusions: NACT-nPC can improve the complete response rate of patients with locally advanced cervical cancer followed by concurrent chemoradiotherapy, and the toxicity is tolerable. Furthermore, we suspect the NACT-nPC can improve the survival of the patients. However, further prospective studies are needed to confirm this result.

Three case reports of radiation-induced glioblastoma after complete remission of acute lymphoblastic leukemia

2018 ◽  
Vol 35 (2) ◽  
pp. 114-122
Author(s):  
Takumi Kajitani ◽  
Masayuki Kanamori ◽  
Ryuta Saito ◽  
Yuko Watanabe ◽  
Hiroyoshi Suzuki ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Complete Remission ◽  
Case Reports ◽  
Lymphoblastic Leukemia ◽  
Radiation Induced

scholarly journals IL-23 Expression in Stewart-Treves Syndrome: Two Case Reports and Immunohistochemical Investigation

2020 ◽  
Vol 13 (1) ◽  
pp. 462-467
Author(s):  
Saaya Yoshida ◽  
Taku Fujimura ◽  
Kentaro Ohuchi ◽  
Yumi Kambayashi ◽  
Yuichiro Segawa ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Immunohistochemical Staining ◽  
Penile Cancer ◽  
Case Reports ◽  
Radical Mastectomy ◽  
Lymph Edema ◽  
Immunohistochemical Investigation ◽  
Radical Dissection

Stewart-Treves syndrome (STS) is a rare cutaneous lymphangiosarcoma developing from chronic lymph edema as a consequence of radical mastectomy or surgical invasion of the groin for the treatment of cervical or penile cancer. Previous reports suggested possible mechanisms in the development of lymphangiosarcoma that correlate with the immunological background of STS patients. In this report, we described two cases of STS developing in patients who underwent radical dissection for cervical cancer, we employed immunohistochemical staining of IL-23 and IL-17.

scholarly journals Secondary uterine carcinosarcoma after concurrent chemoradiotherapy for cervical cancer: Case reports

2017 ◽  
Vol 21 ◽  
pp. 81-83
Author(s):  
Akihiko Wakayama ◽  
Wataru Kudaka ◽  
Tadaharu Nakasone ◽  
Yusuke Taira ◽  
Yoichi Aoki
Keyword(s):  
Cervical Cancer ◽  
Concurrent Chemoradiotherapy ◽  
Case Reports ◽  
Cancer Case ◽  
Uterine Carcinosarcoma ◽  
Cervical Cancer Case

scholarly journals Septic Arthritis of the Hip Joint in Cervical Cancer Patients after Radiotherapy: Three Case Reports

2001 ◽  
Vol 9 (2) ◽  
pp. 41-45 ◽  
Author(s):  
Shu-Hua Yang ◽  
Rong-Sen Yang ◽  
Chin-Lin Tsai
Keyword(s):  
Cervical Cancer ◽  
Femoral Head ◽  
Septic Arthritis ◽  
Cancer Patients ◽  
Hip Joint ◽  
Defense Mechanisms ◽  
Case Reports ◽  
Causative Organism ◽  
Total Hip ◽  
Hip Arthroplasties

Cervical cancer patients may experience hip problems related to the cancer itself or therapeutic management for the cancer. Septic arthritis should be one of the possibilities but there have been no reports on this. Here we present three patients who developed hip problems more than two years after radiotherapy with or without a radical operation. One patient was managed as septic arthritis because of significant inflammatory signs around the affected hip joint even though the causative organism was not confirmed. Succeeding total hip arthroplasty functioned well and had no recurrence of infection. The hip problems of the other two patients were diagnosed as radiation osteonecrosis of the femoral head initially. However, Bacteroides fragilis infection was found several months after total hip arthroplasties. Radiotherapy to the pelvis may damage the hip joint and compromise host-defense mechanisms of the pelvic region. Both factors may increase the possibility of infection of hip joints. Further clinical evidence is needed to understand whether subacute or chronic anaerobic infection could also be one of the causes leading to progressive destruction of the femoral head.

scholarly journals Case Report: Solitary Extramedullary Plasmacytoma in the Cervix Misdiagnosed as Cervical Cancer

2021 ◽  
Vol 11 ◽  
Author(s):  
Ji Wang ◽  
Lin Jiang ◽  
Xuejin Ma ◽  
Tingchao Li ◽  
Heng Liu ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Case Reports ◽  
Extramedullary Plasmacytoma ◽  
Benign Tumors ◽  
Solitary Plasmacytoma ◽  
Imaging Findings ◽  
Mri Imaging ◽  
Cervical Lesions ◽  
Imaging Characteristics ◽  
Solitary Extramedullary Plasmacytoma

Solitary plasmacytoma (SP) is a malignant tumor caused by the monoclonal proliferation of plasma cells, representing less than 5% of plasma cell tumors. SP can be categorized into two groups: solitary bone plasmacytoma (SBP) and solitary extramedullary plasmacytoma (SEP). SEP most commonly occurs in the head and neck and is rarely located in the reproductive system. Here, we report a case of a 77-year-old woman with SEP in the cervix who had a 7-day history of vaginal bleeding. Ultrasonography and magnetic resonance imaging (MRI) showed an oval mass in the cervix, which was initially considered as neoplastic lesions and highly suspected to be cervical cancer, but cervical leiomyoma and other benign tumors cannot be completely excluded. Subsequently, cervical biopsy showed that the tumor was SEP, and then the patient underwent surgery. The postoperative pathological diagnosis was also SEP, which confirmed the radiologist’s misjudgment. In conclusion, SEP that occurs in the cervix is remarkably rare, and only nine cases have been reported in the cervix. No case reports to date have described in detail the imaging findings of cervical SEP. This study demonstrates the MRI imaging characteristics of a patient with SEP of the cervix and reviews the imaging findings of SEP reported in the previous literature, in order to provide more extensive insights for radiologists to consider the differential diagnosis of cervical lesions.

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