scholarly journals PHYLLODES TUMORS OF THE BREAST: 3 CASE REPORTS WITH DYNAMIC MRI AND IMMUNOHISTOCHEMICAL STAINING

2004 ◽  
Vol 65 (8) ◽  
pp. 2077-2082
Author(s):  
Masato FUJIYOSHI ◽  
Masato TAKAHASHI ◽  
Kazunori TAGUCHI ◽  
Hiromasa TAKAHASHI ◽  
Tomoo ITO ◽  
...  
Keyword(s):  
Immunohistochemical Staining ◽  
Case Reports ◽  
Dynamic Mri ◽  
Phyllodes Tumors

scholarly journals IL-23 Expression in Stewart-Treves Syndrome: Two Case Reports and Immunohistochemical Investigation

2020 ◽  
Vol 13 (1) ◽  
pp. 462-467
Author(s):  
Saaya Yoshida ◽  
Taku Fujimura ◽  
Kentaro Ohuchi ◽  
Yumi Kambayashi ◽  
Yuichiro Segawa ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Immunohistochemical Staining ◽  
Penile Cancer ◽  
Case Reports ◽  
Radical Mastectomy ◽  
Lymph Edema ◽  
Immunohistochemical Investigation ◽  
Radical Dissection

Stewart-Treves syndrome (STS) is a rare cutaneous lymphangiosarcoma developing from chronic lymph edema as a consequence of radical mastectomy or surgical invasion of the groin for the treatment of cervical or penile cancer. Previous reports suggested possible mechanisms in the development of lymphangiosarcoma that correlate with the immunological background of STS patients. In this report, we described two cases of STS developing in patients who underwent radical dissection for cervical cancer, we employed immunohistochemical staining of IL-23 and IL-17.

scholarly journals Malignant Phyllodes Tumor of the Breast with Metastasis to the Pancreas: A Case Report and Review of Literature

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
R. A. Amir ◽  
Rola S. Rabah ◽  
S. S. Sheikh
Keyword(s):  
Case Report ◽  
Breast Neoplasms ◽  
Distant Metastasis ◽  
Case Reports ◽  
Phyllodes Tumor ◽  
Pancreatic Metastasis ◽  
Rare Tumor ◽  
Review Of Literature ◽  
Malignant Phyllodes Tumor ◽  
Phyllodes Tumors

Phyllodes tumor (PT) is a rare tumor of the breast accounting for approximately 1% of all breast neoplasms. In 1838, J. Muller coined the term “cystosarcoma phyllodes” based on the leaf-like projections of the tumor extending into the cystic spaces and sarcomatous stromal growth. However, seeing as up to 70% of phyllodes tumors are benign, “cystosarcoma” was removed, and the tumor is now recognized simply as phyllodes tumor. It is mainly seen in females between the ages of 35 and 55. Although most phyllodes tumors are benign, malignant cases do uncommonly occur, 22% of which have distant metastasis typically to the lungs and bones. Rarely, this tumor metastasizes to other locations. Herein, we report a case of malignant phyllodes tumor with metastasis to the pancreas. According to our knowledge, only 3 case reports of pancreatic metastasis from malignant phyllodes tumor have been reported in literature thus far. We aim to increase awareness among physicians of this rare metastasic potential of the uncommonly encountered malignant phyllodes tumor.

scholarly journals Giant Benign Mammary Phyllodes Tumor: Report of a Case and Review of the Literature

2021 ◽  
pp. 123-133
Author(s):  
Ricardo Fernández-Ferreira ◽  
Andrés Arroyave-Ramírez ◽  
Daniel Motola-Kuba ◽  
Gabriela Alvarado-Luna ◽  
Ileana Mackinney-Novelo ◽  
...  
Keyword(s):  
Case Reports ◽  
Standard Of Care ◽  
Phyllodes Tumor ◽  
Surgical Excision ◽  
Axillary Lymph Node Metastasis ◽  
Adjuvant Radiation ◽  
Axillary Lymph ◽  
Phyllodes Tumors ◽  
Complete Surgical Excision ◽  
Mexican Woman

Phyllodes tumor of the breast is an infrequently encountered fibroepithelial neoplasm, which accounts for 0.3–1% of all tumors. Few case reports have described the occurrence of giant phyllodes tumor. To our knowledge, about 20% of phyllodes tumors would be considered giant benign. Complete surgical excision is the standard of care for giant benign phyllodes tumors; axillary lymph node metastasis is rare, and dissection should be limited to patients with pathologic evidence of tumor in the lymph nodes. We report the case of a 40-year-old Mexican woman with giant mammary tumor who underwent a right total mastectomy. The pathology results showed a benign phyllodes tumor 4,857 g in weight and 40.2 × 36.3 × 15 cm in size. We do not suggest adjuvant radiation therapy for patients with benign phyllodes tumors that are widely excised. A review of the pertinent literature was performed.

scholarly journals The Role of Dynamic Magnetic Resonance Imaging in Cervical Spondylotic Myelopathy

2017 ◽  
Vol 11 (6) ◽  
pp. 1008-1015 ◽  
Author(s):  
John Paul Kolcun ◽  
Lee Onn Chieng ◽  
Karthik Madhavan ◽  
Michael Y. Wang
Keyword(s):  
Spinal Cord ◽  
Cervical Spondylotic Myelopathy ◽  
English Language ◽  
Case Reports ◽  
Preoperative Evaluation ◽  
Case Series ◽  
Dynamic Mri ◽  
Cord Compression ◽  
Cervical Cord ◽  
Dynamic Changes

<p>Dynamic spinal cord compression has been investigated for several years, but until the advent of open MRI, the use of dynamic MRI (dMRI) did not gain popularity. Several publications have shown that cervical cord compression is both static and dynamic. On many occasions the evaluation of cervical spondylotic myelopathy (CSM) is straightforward, but patients are frequently encountered with a significantly worse clinical examination than would be suggested by radiological images. In this paper, we present an extensive review of the literature in order to describe the importance of dMRI in various settings and applications. A detailed literature review was performed in the Medline and Pubmed databases using the terms “cervical spondylotic myelopathy”, “dynamic MRI”, “kinetic MRI”, and “myelomalalcia” for the period of 1980-2016. The study was limited to English language, human subjects, case series, retrospective studies, prospective reports, and clinical trials. Reviews, case reports, cadaveric studies, editorials, and commentaries were excluded. The literature search yielded 180 papers, 19 of which met inclusion criteria. However, each paper had evaluated results and outcomes in different ways. It was not possible to compile them for meta-analysis or pooled data evaluation. Instead, we evaluated individual studies and present them for discussion. We describe a number of parameters evaluated in 2661 total patients, including dynamic changes to spinal cord and canal dimensions, transient compression of the cord with changes in position, and the effects of position on the intervertebral disc. dMRI is a useful tool for understanding the development of CSM. It has found several applications in the diagnosis and preoperative evaluation of many patients, as well as certain congenital dysplasias and Hirayama disease. It is useful in correlating symptoms with the dynamic changes only noted on dMRI, and has reduced the incidence of misdiagnosis of myelopathy.</p>

scholarly journals Hepatoid Adenocarcinoma of the Lung

2021 ◽  
Vol 20 ◽  
pp. 153303382110579
Author(s):  
Meihui Li ◽  
Ying Fan ◽  
Hongyang Lu
Keyword(s):  
Immunohistochemical Staining ◽  
Case Reports ◽  
Hepatoid Adenocarcinoma ◽  
Pathological Features ◽  
High Concentration ◽  
Statistical Research ◽  
Rare Type ◽  
Adenocarcinoma Of The Lung ◽  
Complete Surgical Resection ◽  
Clinical And Pathological Features

Hepatoid adenocarcinoma of the lung (HAL) is an comparatively rare malignant tumor originating from the lung with shorter survival. HAL morphologically and pathologically exhibits hepatocellular carcinoma (HCC)-like characteristics, while its clinical features resemble pulmonary adenocarcinoma. High concentration of alpha-fetoprotein (AFP) is often detected in the serum of HAL patients with no hepatic occupying lesion. Patients with AFP-negative HAL survive a few months longer than those with positive AFP test. HAL is a rare type of carcinoma, so there is a lack of systematic and extensive statistical research. The treatment strategy for HAL is similar to common lung adenocarcinoma. Complete surgical resection and adjuvant chemotherapy are the current major treatments for HAL patients. There are also a few of case reports suggesting that HAL patients may benefit from immunotherapy and targeted therapy. This review focuses on the clinical and pathological features, immunohistochemical staining characteristics, treatment and prognosis of HAL.

Comparison of localization of metallothionein in tissues of metallothionein-deficient mice

1995 ◽  
Vol 53 ◽  
pp. 1042-1043
Author(s):  
H. Nishimura ◽  
R Nishimura ◽  
D.L. Adelson ◽  
A.E. Michaelska ◽  
K.H.A. Choo ◽  
...  
Keyword(s):  
Metal Binding ◽  
Immunohistochemical Staining ◽  
Squamous Epithelium ◽  
Rabbit Antiserum ◽  
Slight Modification ◽  
Positive Control ◽  
Heavy Metal Binding ◽  
Critical Organ ◽  
Metal Binding Protein ◽  
Deficient Mice

Metallothionein (MT), a cysteine-rich heavy metal binding protein, has several isoforms designated from I to IV. Its major isoforms, I and II, can be induced by heavy metals like cadmium (Cd) and, are present in various organs of man and animals. Rodent testes are a critical organ to Cd and it is still a controversial matter whether MT exists in the testis although it is clear that MT is not induced by Cd in this tissue. MT-IV mRNA was found to localize within tongue squamous epithelium. Whether MT-III is present mainly glial cells or neurons has become a debatable topic. In the present study, we have utilized MT-I and II gene targeted mice and compared MT localization in various tissues from both MT-deficient mice and C57Black/6J mice (C57BL) which were used as an MT-positive control. For MT immunostaining, we have used rabbit antiserum against rat MT-I known to cross-react with mammalian MT-I and II and human MT-III. Immunohistochemical staining was conducted by the method described in the previous paper with a slight modification after the tissues were fixed in HistoChoice and embedded in paraffin.

Case Reports Link ADHD Stimulants to Skin Eruptions

2011 ◽  
Vol 45 (12) ◽  
pp. 10
Author(s):  
SHERRY BOSCHERT
Keyword(s):  
Case Reports
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