Evaluation of Endometrial Cytology Prepared with the Becton Dickinson SurePath™ Method: A Pilot Study by the Osaki Study Group

2014 ◽  
Vol 58 (2) ◽  
pp. 153-161 ◽  
Author(s):  
Kenji Yanoh ◽  
Yoshiaki Norimatsu ◽  
Satoru Munakata ◽  
Toshiya Yamamoto ◽  
Yutaka Nakamura ◽  
...  
Cytopathology ◽  
2016 ◽  
Vol 27 (6) ◽  
pp. 472-478 ◽  
Author(s):  
Y. Norimatsu ◽  
T. Yamaguchi ◽  
T. Taira ◽  
H. Abe ◽  
H. Sakamoto ◽  
...  

1989 ◽  
pp. 367-372 ◽  
Author(s):  
D. M. Rosenbaum ◽  
J. C. Grotta ◽  
F. M. Yatsu ◽  
C. M. Picone ◽  
L. C. Pettigrew ◽  
...  

2021 ◽  
Vol 60 (5) ◽  
pp. 253-259
Author(s):  
Kosei SHIRAHAMA ◽  
Yuichiro SATO ◽  
Kazuaki KIYOYAMA ◽  
Hiroshi NOGUCHI ◽  
Tohru HAYASHI ◽  
...  

1994 ◽  
Vol 12 (3) ◽  
pp. 522-531 ◽  
Author(s):  
L White ◽  
G McCowage ◽  
G Kannourakis ◽  
V Nayanar ◽  
L Colnan ◽  
...  

PURPOSE This pilot study of the Australia and New Zealand Childhood Cancer Study Group investigated the effectiveness and toxicity of a regimen incorporating vincristine (VCR), etoposide, and divided-dose, escalating cyclophosphamide (CPA) (VETOPEC) in 23 patients aged 1 to 20 years with solid tumors. PATIENTS AND METHODS Seventeen patients (group A) had recurrent or refractory tumors after prior multiagent therapy, and six patients (group B) with adverse prognostic indicators were treated at initial presentation. Treatment cycles were 21 to 28 days and consisted of vincristine (0.05 mg/kg) on days 1 and 14, with etoposide (2.5 mg/kg/d) plus escalating CPA on days 1, 2, and 3. The CPA dosage was escalated from 30 mg/kg/d in cycle no. 1 by 5 mg/kg/d in each cycle to a maximum of 55 mg/kg/d in cycle no. 6. RESULTS Of 20 patients assessable for tumor response, 19 (95%) responded after two to six cycles of VETOPEC: seven complete responses (CRs); eight very good partial responses (VGPRs); and four partial responses (PRs). In group A, 13 of 14 (93%) assessable patients responded (five CRs, four VGPRs, four PRs), and in group B, five stage IV and one stage III patient achieved two CRs and four VGPRs. The principal toxicity was myelosuppression. Grade IV neutropenia occurred after 98% of cycles, and the incidence of grade IV thrombocytopenia increased from 37% after cycle no. 1 to 91% after cycle no. 6 (P = .002). A total of 115 cycles delivered were followed by 62 febrile admissions (54%), and showed a significant rise with increasing cycles (P = .001). One patient died of septicemia. CONCLUSION This combination and scheduling produced a high response rate in patients with recurrent, refractory, or advanced solid tumors of childhood. Further studies of this regimen and of strategies to reduce hematologic toxicity are warranted.


2020 ◽  
Vol 8 (2) ◽  
pp. 33 ◽  
Author(s):  
Alessandro Nota ◽  
Floriana Bosco ◽  
Shideh Ehsani ◽  
Francesca Giugliano ◽  
Giulia Moreo ◽  
...  

Objective: This pilot study is a prospective controlled clinical trial, designed to evaluate the short-term clinical results (the plaque index) of an educational/motivational program for home oral hygiene, directed to children and adolescents who live in family-homes. Methods: The setting of the project was the province of Milan (Italy), where two family-homes were selected. The study group included 26 children (16 females and 10 males) aged between 7 and 15 years, of Italian nationality, from the family-home communities. The control group included 26 children (15 females and 11 males, aged between 7 and 15 years) of Italian nationality, matched for age and gender distribution with the study group, that were not in a socially disadvantaged condition. Collection of the plaque index (PI) was performed at t0. Then, all basic oral hygiene instructions were given to all children/adolescents and their educators. Education and motivation were repeated in the same way after 4–7 weeks (T1), and after 10–12 weeks (T2). The PI was taken also at T1 and T2. Results: An improvement in the PI was generally found in both groups, but there was no statistically significant difference between the two groups over time. Multivariate analysis of variance (MANOVA) revealed a statistically significant effect of time [F (1, 52) = 90.73, p < 0.001], regardless of the assignment group, in consequence of which the plaque index presented a moderate and significant improvement. Conclusion: The present data confirm the validity of the educational/motivational program to improve oral hygiene in children/adolescents, regardless of the assignment group.


2007 ◽  
Vol 14 (6) ◽  
pp. S17
Author(s):  
O. Ceci ◽  
L. Resta ◽  
G. Pontrelli ◽  
M. Achilarre

Sign in / Sign up

Export Citation Format

Share Document