Effect of Duodenal Ulcerogens Mepirizole and Propionitrile on Small Intestinal and Liver Alkaline Phosphatase Activity in Rats

Digestion ◽  
1990 ◽  
Vol 47 (2) ◽  
pp. 61-70 ◽  
Author(s):  
I. Japundzic ◽  
E. Levi ◽  
Lj.S. Rakic-Stojiljkovic
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Alkaline Phosphatase Activity ◽  
Small Intestinal

Small-Intestinal Changes Induced by an Elemental Diet (Vivonex) in Normal Rats

1978 ◽  
Vol 55 (5) ◽  
pp. 509-511 ◽  
Author(s):  
L. M. Nelson ◽  
H. A. Carmichael ◽  
R. I. Russell ◽  
F. D. Lee
Keyword(s):  
Alkaline Phosphatase ◽  
Protein Content ◽  
Phosphatase Activity ◽  
Alkaline Phosphatase Activity ◽  
Elemental Diet ◽  
Normal Diet ◽  
Villus Height ◽  
Disaccharidase Activity ◽  
Control Value ◽  
Small Intestinal

1. Rats were fed with the elemental diet Vivonex for 1 or 3 months and their jejunal histology was compared with that of an equal number of rats fed on a normal diet. 2. After 1 month of Vivonex feeding a significant reduction in the ratio of crypt height: villus height (CH: VH) was found in the Vivonex-fed rats (n = 4) compared with the control rats (n = 4) (P < 0.05). 3. After 3 months the CH:VH ratio was also reduced in the Vivonex-fed rats (n = 18) compared with control rats (n = 18) (P < 0.002). Villus height was significantly increased (P < 0.002) and crypt height decreased (P < 0.05). 4. Jejunal protein content, alkaline phosphatase and disaccharidase activity were also determined in 12 control and 12 Vivonex-fed rats from the 3 months study. 5. Alkaline phosphatase activity was increased from a control value of 201 ± 8 to 243 ± 15 munits/cm in the Vivonex-fed rats (n = 12) (P < 0.05) but no significant changes in lactase, sucrase or maltase activities were found. 6. The observed decrease in the CH:VH ratio suggested an improved survival of the mature enterocyte population during elemental diet feeding.

scholarly journals Alkaline Phosphatase and Disaccharide Activity in Barrett's Columnar Lined Esophagus

1988 ◽  
Vol 2 (1) ◽  
pp. 15-17
Author(s):  
S.N. Sullivan ◽  
R.J. Darwish ◽  
M. Troster
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Alkaline Phosphatase Activity ◽  
Biochemical Markers ◽  
Squamous Epithelium ◽  
Disaccharidase Activity ◽  
Columnar Lined Esophagus ◽  
The Mean ◽  
Small Intestinal ◽  
Standard Deviations

Esophageal mucosal biopsies of 15 patients with normal squamous epithelium, 11 with inflamed squamous epithelium and 23 with Barrete's columnar lined esophagus were assayed for alkaline phosphatase and disaccharidase activity. Seven of the patients with Barrett's esophagus had alkaline phosphatase activity greater than three standard deviations above the mean of the 15 patients with normal squamous epithelium. Five of these seven also had disaccharidase activity three standard deviations or greater above normal. One patient with esophagitis, but without columnar epithelium, had a small increase in alkaline phosphatase and disaccharidase activity. The production of biochemical markers of small intestinal structure may he another indicator of the pluripotential nature of Barrett's epithelium.

LEUCOCYTE METABOLISM IN PREGNANCY

1960 ◽  
Vol XXXV (IV) ◽  
pp. 575-584 ◽  
Author(s):  
C. Borel ◽  
J. Frei ◽  
A. Vannotti
Keyword(s):  
Alkaline Phosphatase ◽  
Oxygen Consumption ◽  
Pregnant Women ◽  
Phosphatase Activity ◽  
Alkaline Phosphatase Activity ◽  
Lactate Production ◽  
Glucose Consumption ◽  
In Pregnancy

ABSTRACT Enzymatic studies, on leucocytes of pregnant women, show an increase of the alkaline phosphatase activity and a decrease of the glucose consumption and lactate production, as well as of proteolysis. The oxygen consumption, with succinate as substrate, does not vary.

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