Correlation between X-chromosome inactivation and cell differentiation in female preimplantation mouse embryos

1985 ◽  
Vol 39 (3) ◽  
pp. 210-219 ◽  
Author(s):  
O. Sugawara ◽  
N. Takagi ◽  
M. Sasaki
2014 ◽  
Vol 4 (1) ◽  
Author(s):  
Miki Soma ◽  
Yoshitaka Fujihara ◽  
Masaru Okabe ◽  
Fumitoshi Ishino ◽  
Shin Kobayashi

1990 ◽  
Vol 10 (9) ◽  
pp. 4987-4989 ◽  
Author(s):  
J Singer-Sam ◽  
M Grant ◽  
J M LeBon ◽  
K Okuyama ◽  
V Chapman ◽  
...  

A HpaII-PCR assay was used to study DNA methylation in individual mouse embryos. It was found that HpaII site H-7 in the CpG island of the X-chromosome-linked Pgk-1 gene is less than or equal to 10% methylated in oocytes and male embryos but becomes 40% methylated in female embryos at 6.5 days; about the time of X-chromosome inactivation of the inner cell mass.


1990 ◽  
Vol 10 (9) ◽  
pp. 4987-4989
Author(s):  
J Singer-Sam ◽  
M Grant ◽  
J M LeBon ◽  
K Okuyama ◽  
V Chapman ◽  
...  

A HpaII-PCR assay was used to study DNA methylation in individual mouse embryos. It was found that HpaII site H-7 in the CpG island of the X-chromosome-linked Pgk-1 gene is less than or equal to 10% methylated in oocytes and male embryos but becomes 40% methylated in female embryos at 6.5 days; about the time of X-chromosome inactivation of the inner cell mass.


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