Translocation breakpoint possibly predisposes to nonrandom X-chromosome inactivation in mouse embryos bearing Searle’s T(X;16)16H translocation

1998 ◽  
Vol 80 (1-4) ◽  
pp. 173-178 ◽  
Author(s):  
H. Ogura ◽  
S. Takada ◽  
N. Mise ◽  
M. Sugimoto ◽  
S.-S. Tan, ◽  
...  
1990 ◽  
Vol 10 (9) ◽  
pp. 4987-4989 ◽  
Author(s):  
J Singer-Sam ◽  
M Grant ◽  
J M LeBon ◽  
K Okuyama ◽  
V Chapman ◽  
...  

A HpaII-PCR assay was used to study DNA methylation in individual mouse embryos. It was found that HpaII site H-7 in the CpG island of the X-chromosome-linked Pgk-1 gene is less than or equal to 10% methylated in oocytes and male embryos but becomes 40% methylated in female embryos at 6.5 days; about the time of X-chromosome inactivation of the inner cell mass.


1990 ◽  
Vol 10 (9) ◽  
pp. 4987-4989
Author(s):  
J Singer-Sam ◽  
M Grant ◽  
J M LeBon ◽  
K Okuyama ◽  
V Chapman ◽  
...  

A HpaII-PCR assay was used to study DNA methylation in individual mouse embryos. It was found that HpaII site H-7 in the CpG island of the X-chromosome-linked Pgk-1 gene is less than or equal to 10% methylated in oocytes and male embryos but becomes 40% methylated in female embryos at 6.5 days; about the time of X-chromosome inactivation of the inner cell mass.


2014 ◽  
Vol 4 (1) ◽  
Author(s):  
Miki Soma ◽  
Yoshitaka Fujihara ◽  
Masaru Okabe ◽  
Fumitoshi Ishino ◽  
Shin Kobayashi

Nature ◽  
1978 ◽  
Vol 271 (5645) ◽  
pp. 547-549 ◽  
Author(s):  
MATTHEW H. KAUFMAN ◽  
MARIJA GUC-CUBRILO ◽  
MARY F. LYON

Nature ◽  
1978 ◽  
Vol 274 (5670) ◽  
pp. 500-503 ◽  
Author(s):  
CHARLES J. EPSTEIN ◽  
SANDRA SMITH ◽  
BRUCE TRAVIS ◽  
GEORGIANNE TUCKER

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