scholarly journals Minor Salivary Gland Tumours of Upper Aerodigestive Tract: A Clinicopathological Study

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Grażyna Wyszyńska-Pawelec ◽  
Michał Gontarz ◽  
Jan Zapała ◽  
Mariusz Szuta
Keyword(s):  
Salivary Gland ◽  
Minor Salivary Gland ◽  
Relative Survival ◽  
Aerodigestive Tract ◽  
Malignant Tumours ◽  
Upper Aerodigestive Tract ◽  
Female Ratio ◽  
Salivary Gland Tumours ◽  
Results Of Treatment ◽  
Radial Forearm

The aim of this retrospective study of 56 patients with minor salivary gland tumours (MSGTs) of the upper aerodigestive tract is to present demographic features, distribution of tumours as well as methods and results of treatment performed in our institution over a 10-year period. Of 221 patients with salivary gland tumours, 56 patients with MSGT were selected. There were 36 female and 20 male patients aged from 8 to 81 years. Male-to-female ratio was 1 : 2 in the group of benign MSGT and 1 : 1.7 in the group of malignant tumours. The palate was the most frequent site of MSGT (45.6%), followed by buccal mucosa (19.3%). Of all MSGTs 63.2% were malignant, and 36.8% were benign. Adenoid cystic carcinoma was the most common neoplasm (31.6%), followed by pleomorphic adenoma (29.8%). Surgery was the method of choice in the treatment of patients with MSGT. Postoperative defects were reconstructed by prosthetic obturators, local flaps, and free radial forearm flap. Relative survival for patients with malignant MSGT was 88% at three years and 71.5% at five years. MSGTs are more frequent in females and predominantly affect the palate. Malignant MSGTs are more common than benign.

scholarly journals Salivary gland tumours: a hospital-based study on demographic and incidence pattern, histopathological types and treatment strategy

2020 ◽  
Vol 6 (12) ◽  
pp. 2218
Author(s):  
M. K. Mili ◽  
Hirak Jyoti Das ◽  
Asha Saikia ◽  
N. J. Saikia ◽  
J. Phookan ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Treatment Strategy ◽  
Tertiary Care ◽  
Minor Salivary Gland ◽  
Salivary Gland Tumour ◽  
Female Ratio ◽  
Salivary Gland Tumours ◽  
Gland Tumour

<p><strong>Background: </strong>Salivary gland tumours constitute 3-4% of all head and neck cancers (mostly benign). These tumours are epithelial (95%) or mesenchymal in origin. Pleomorphic adenoma is the most common benign salivary gland tumour and mucoepidermoid carcinoma (45%) is the most common malignant salivary gland tumour followed by adenoid cystic carcinoma (30%). The parotid, submandibular and the minor salivary glands of palate are commonly involved and the sublingual gland is rarely affected.</p><p><strong>Methods: </strong>Hospital based cross sectional study was done in a tertiary care centre during a period of 1 year, which included 21 patients (10 men and 11 women). Patients were analysed according to age, gender, food habits, histopathological type and site of the tumour and treatment strategy.</p><p><strong>Results: </strong>All the cases were from upper Assam province sharing a particular demographic pattern between 19-65 years. Peak incidence in males was fourth decade and females was third decade. Male female ratio was 0.9:1. Out of 21 cases, 14 were parotid gland tumours, 6 submandibular gland tumours and 1 minor salivary gland tumour. Most of the tumours were benign (16) and 5 were malignant.</p><p><strong>Conclusions: </strong>Two patients were of age 19 years which is conflicting the normal national incidence. All cases belonged to lower economic strata with decreased intake of beta carotene enriched food items. The most common site is parotid gland and most common tumour is pleomorphic adenoma which is in accordance to other studies. Benign cases were subjected to superficial parotidectomy and malignant cases to total parotidectomy with neck dissection.</p>

Regenerative medicine for end-stage fibrosis and tissue loss in the upper aerodigestive tract: a twenty-first century review

2021 ◽  
pp. 1-13
Author(s):  
F R Green ◽  
N M Shubber ◽  
F S Koumpa ◽  
N J I Hamilton
Keyword(s):  
Salivary Gland ◽  
Regenerative Medicine ◽  
Vocal Fold ◽  
Aerodigestive Tract ◽  
First Century ◽  
Tissue Loss ◽  
Cochrane Library ◽  
Upper Aerodigestive Tract ◽  
Twenty First Century ◽  
End Stage

Abstract Objective This review assesses regenerative medicine of the upper aerodigestive tract during the first two decades of the twenty-first century, focusing on end-stage fibrosis and tissue loss in the upper airways, salivary system, oropharynx and tongue. Method PubMed, Embase, Google Scholar, Cochrane Library, Medline and clinicaltrials.org were searched from 2000 to 2019. The keywords used were: bioengineering, regenerative medicine, tissue engineering, cell therapy, regenerative surgery, upper aerodigestive tract, pharynx, oropharynx, larynx, trachea, vocal cord, tongue and salivary glands. Original studies were subcategorised by anatomical region. Original human reports were further analysed. Articles on periodontology, ear, nose and maxillofacial disorders, and cancer immunotherapy were excluded. Results Of 716 relevant publications, 471 were original studies. There were 18 human studies included, within which 8 reported airway replacements, 5 concerned vocal fold regeneration and 3 concerned salivary gland regeneration. Techniques included cell transplantation, injection of biofactors, bioscaffolding and bioengineered laryngeal structures. Conclusion Moderate experimental success was identified in the restoration of upper airway, vocal fold and salivary gland function. This review suggests that a shift in regenerative medicine research focus is required toward pathology with a higher disease burden.

Case of labial sclerosing polycystic adenoma with ductal carcinoma in situ (DCIS)

2021 ◽  
Vol 14 (8) ◽  
pp. e243736
Author(s):  
Soumya Makarla ◽  
Radhika M Bavle ◽  
Reshma Venugopal ◽  
Sudhakara Muniswamappa
Keyword(s):  
Salivary Gland ◽  
Ductal Carcinoma ◽  
Minor Salivary Gland ◽  
Histopathological Diagnosis ◽  
Epithelial Proliferation ◽  
Upper Lip ◽  
Salivary Gland Tumours ◽  
Pleomorphic Adenomas ◽  
Rare Lesion

Minor salivary gland tumours are enigmatic in their behaviour and presentations. Histopathological diagnosis of these tumours encompasses a large spectrum. Conventionally, small nodular tumours of the upper lip or the labial mucosa are generally adenomas, frequently pleomorphic adenomas. Here, we describe a case of a solitary nodular tumour, occurring in the upper labial mucosa, diagnosed as sclerosing polycystic adenoma (SPA) with intraductal epithelial proliferation of high grade. This is a rare lesion, which has entered into the category of salivary gland tumours recently in the 2017 WHO categorisation. We report a case of paucicystic SPA with intraductal epithelial proliferations in the labial minor salivary gland of a 56-year-old woman, which might be the first report of a case occurring in the upper labial mucosa.

scholarly journals Cytohistopathological Study of Salivary Gland Lesions in Bundelkhand Region, Uttar Pradesh, India

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Anita Omhare ◽  
Sanjeev Kumar Singh ◽  
Jitendra Singh Nigam ◽  
Ankit Sharma
Keyword(s):  
Salivary Gland ◽  
Low Cost ◽  
Uttar Pradesh ◽  
Diagnostic Technique ◽  
High Specificity ◽  
Turnaround Time ◽  
Malignant Tumours ◽  
Female Ratio ◽  
Specificity And Sensitivity ◽  
Benign Tumours

Background. FNAC is a useful method for evaluating suspicious salivary glands lesions due to its low cost, minimum morbidity, rapid turnaround time, high specificity, and sensitivity. Aim. To know the frequency of the salivary gland lesions and cytohistological correlation in the Jhansi region, Uttar Pradesh, India. Material and Methods. In present study 124 cases were included and cytohistological correlation was made in 86 cases only. FNA was performed by using a 23/24-gauge needle without local anaesthesia. Air dried and 95% ethyl alcohol fixed wet smears were stained with Giemsa stain and Papanicolaou stain, respectively. Paraffin embedded tissue sections were stained with Haematoxylin and Eosin. Results. Parotid gland was the most commonly involved salivary gland. The commonest age group was 20 to 29 years, 30 to 39 years, and 60 to 69 years for nonneoplastic lesions, benign tumours, and malignant tumours, respectively. The overall male to female ratio was 1.17 : 1. The diagnostic accuracy of FNAC was 100%, 93.3%, and 88.2% for nonneoplastic lesions, benign tumours, and malignant tumours, respectively. Conclusion. The high accuracy, sensitivity, and specificity of FNAC confirm that preoperative cytology is a useful, quick, reliable diagnostic technique for rapid diagnosis and suitable for developing countries.

External beam radiotherapy for the treatment of feline salivary gland carcinoma: six new cases and a review of the literature

2018 ◽  
Vol 21 (2) ◽  
pp. 186-194
Author(s):  
Laura Blackwood ◽  
Aaron Harper ◽  
James Elliott ◽  
Irina Gramer
Keyword(s):  
Radiation Therapy ◽  
Salivary Gland ◽  
Postoperative Radiotherapy ◽  
External Beam Radiotherapy ◽  
Primary Tumour ◽  
Case Series ◽  
Salivary Gland Carcinoma ◽  
Malignant Tumours ◽  
Salivary Gland Tumours ◽  
Gland Carcinoma

Case series summary Salivary gland carcinoma is uncommon in cats. We report the outcome of radiation therapy in six cases (four salivary gland adenocarcinomas, one tubulopapillary adenocarcinoma, one carcinoma). Five were treated after surgical excision of the primary tumour, but four had gross disease (primary or metastatic) at the time of starting radiotherapy. Exact progression-free interval from the start of radiotherapy in the two cats where this was known was 120 and 144 days, respectively. One cat was signed off at 766 days with no evidence of recurrence. Another cat was in remission at 202 days (when last seen by the referring practice) but subsequently developed recurrence (date uncertain). Survival time was known for three cats (55 days, 258 days and 570 days from initiation of radiotherapy, respectively). In two cases, locoregional progressive disease (PD) was confirmed, and the other presumed as the cause of death. Two cats, known to have developed PD, were alive at the time of writing (at 206 and 549 days, respectively). No cat died as a result of distant metastatic disease. Relevance and novel information There is a paucity of information on the treatment of salivary gland tumours. In humans, as in cats, there is no optimised standard of care for malignant tumours. It is accepted that, for surgical candidates (even with large tumours), surgery and radiotherapy is superior to radiotherapy alone. However, the benefits of postoperative radiotherapy compared with surgery alone are only clear in patients with high-risk tumours (ie, those with large and invasive primary tumours, close or incomplete margins, high histopathological grade, histological evidence of neural or vascular invasion, or positive lymph nodes). This population is analogous to the population reported here, and likely to most cats presented in practice. Thus, radiation therapy may help improve locoregional control and survival in cats.

Palatal pleomorphic adenoma in a child

1995 ◽  
Vol 109 (4) ◽  
pp. 343-345 ◽  
Author(s):  
A. Noghreyan ◽  
A. Gatot ◽  
E. Maor ◽  
D. M. Fliss
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Hard Palate ◽  
Minor Salivary Gland ◽  
Salivary Gland Tumours ◽  
A Minor ◽  
Benign Salivary Gland Tumours

AbstractBenign salivary gland tumours in childhood are rare. We present a case of a pleomorphic adenoma arising in a minor salivary gland within the hard palate, review the literature and discuss the diagnostic and therapeutic features of the condition.

scholarly journals Review of Salivary Gland Neoplasms

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Victor Shing Howe To ◽  
Jimmy Yu Wai Chan ◽  
Raymond K. Y. Tsang ◽  
William I. Wei
Keyword(s):  
Salivary Gland ◽  
Regional Lymph Node ◽  
Postoperative Radiotherapy ◽  
Surgical Excision ◽  
Needle Aspiration ◽  
Low Grade ◽  
Malignant Tumours ◽  
Parotid Glands ◽  
Salivary Gland Tumours ◽  
Mri Scans

Salivary gland tumours most often present as painless enlarging masses. Most are located in the parotid glands and most are benign. The principal hurdle in their management lies in the difficulty in distinguishing benign from malignant tumours. Investigations such as fine needle aspiration cytology and MRI scans provide some useful information, but most cases will require surgical excision as a means of coming to a definitive diagnosis. Benign tumours and early low-grade malignancies can be adequately treated with surgery alone, while more advanced and high-grade tumours with regional lymph node metastasis will require postoperative radiotherapy. The role of chemotherapy remains largely palliative. This paper highlights some of the more important aspects in the management of salivary gland tumours.

scholarly journals Rare Occurrence of Lip Spindle Cell Lipoma

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Sandra Girgis ◽  
Leo Cheng
Keyword(s):  
Salivary Gland ◽  
Spindle Cell ◽  
Minor Salivary Gland ◽  
Surgical Excision ◽  
Spindle Cell Lipoma ◽  
Lower Lip ◽  
Salivary Gland Tumours ◽  
Minor Salivary Gland Tumour ◽  
A Minor ◽  
Slow Growing

Spindle cell lipoma (SCL) is a rare distinct variant of lipoma, which presents as a painless, circumscribed, slow-growing, superficial lesion on the lip and can mimic a minor salivary gland tumour. We present a slow growing lower lip lesion and its management.Case Report. A 38-year-old female gave an eight-year history of a slow-growing mass on her lower lip with intermittent change in size. She presented with a submucosal nodule and thin overlying mucosa adjacent to the vermilion border. Surgical excision was carried as the diagnostic and therapeutic approach.Conclusion. Lip SCL is rare, and surgical excision is advocated in order to exclude underlying pathology and minor salivary gland tumours.

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