Pleomorphic adenoma of dorsum of the nose: a rare occurrence

<p class="abstract">Pleomorphic adenoma are common benign salivary gland tumours, which are found in majority in major salivary glands such as parotids and submandibular glands. However, Pleomorphic adenoma to originate from dorsum of the nose is a rare entity. In rare cases, it can be found in unusual sites such as upper aero digestive tracts, palate and lacrimal glands. Complete surgical resection is the treatment of choice. Though, the evolution to malignancy and recurrence is not usually encountered, still a long-term follow-up is recommended. Here, we report a 53 year old female , complained of swelling in the left side of dorsum of nose for 10 years with a feeling of heaviness over the left side of face and difficulty in vision on the side of swelling due to the enlarged size of the swelling which gave a feeling of vision disruption , also had a prior history of incision and drainage 4 years ,done elsewhere. On clinical examination, nodular mass was palpated on left side dorsum of nose which was freely mobile, and Skin over the swelling had blackish pigmentation. Anterior rhinoscopy revealed no abnormalities. Complete surgical excision via a lateral rhinotomy incision was performed. Cytological and histological evaluation revealed the presence of pleomorphic adenoma. We observed a decent cosmetic outcome with no evidence of recurrence.</p>

A Palatal Myoepithelioma

This case report demonstrates the management of a myoepithelioma in the minor salivary glands of the palate. Myoepitheliomas are rare, benign, salivary gland tumours which usually affect the parotid glands. The rare neoplasms only account for 1–1.5% of all salivary gland neoplasms. This case shows a minimal approach to treating this rare tumour found in a rare site. CPD/Clinical Relevance: This case demonstrates the potential for rapid epithelial recovery within the oral cavity.

A Review of Selected Factors of Salivary Gland Tumour Formation and Malignant Transformation

Salivary gland tumours represent about 6% of head and neck neoplasms and about 0.5% of all malignancies in humans. Tumour growth and malignant transformation are complex processes involving various actions of molecules. Furthermore, some malignant salivary gland tumours are deemed to be caused by dedifferentiation or malignant transformation of benign tumours. The mechanisms of this transformation depend on a variety of different elements, such as cell cycle regulators, oncogenes, proteins, angiogenesis factors, and adipocytokines. The authors used PubMed, Medline, and Google websites to find and review the most significant papers related to malignant transformation in benign salivary gland tumours.

Papillary mucous cystadenoma of parotid gland

<p>Cystadenomas are rare benign salivary gland tumours characterised by prominent epithelium-lined papillary projections into the cystic spaces. Cystadenoma accounts for 2% of all salivary gland tumors, occurring most commonly in major salivary glands. Histopathologically there are two variants, papillary and mucinous variant. However very few cases are being reported in literature. We report a case of papillary cystadenoma occuring in parotid gland in a 28 year old male patient. Clinically, it presents as a soft, fluctuant, sessile and non-tender swelling measuring about 4×3.5 cm in diameter. Excisional biopsy was performed. The histopathological features were characteristic of papillary cystadenoma. This article highlights its clinical and histopathological features along with review of literature. </p>

Palatal pleomorphic adenoma in a child

Benign salivary gland tumours in childhood are rare. We present a case of a pleomorphic adenoma arising in a minor salivary gland within the hard palate, review the literature and discuss the diagnostic and therapeutic features of the condition.